Journal Article: Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation
Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019) Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 19: 3775-3790. doi:10.1111/bph.14768
Journal Article: Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis
Yang, Yoon Mee, Noureddin, Mazen, Liu, Cheng, Ohashi, Koichiro, Kim, So Yeon, Ramnath, Divya, Powell, Elizabeth E., Sweet, Matthew J., Roh, Yoon Seok, Hsin, I-Fang, Deng, Nan, Liu, Zhenqiu, Liang, Jiurong, Mena, Edward, Shouhed, Daniel, Schwabe, Robert F., Jiang, Dianhua, Lu, Shelly C., Noble, Paul W. and Seki, Ekihiro (2019) Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine, 11 496: . doi:10.1126/scitranslmed.aat9284
Journal Article: Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps
Chen, Kaiwen W., Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D., von Pein, Jessica B., Broz, Petr, Sweet, Matthew J. and Schroder, Kate (2018) Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science Immunology, 3 26: eaar6676. doi:10.1126/sciimmunol.aar6676
Defining molecular links between immune cell metabolism and inflammation
(2020–2023) NHMRC IDEAS Grants
Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019) Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 19: 3775-3790. doi:10.1111/bph.14768
Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis
Yang, Yoon Mee, Noureddin, Mazen, Liu, Cheng, Ohashi, Koichiro, Kim, So Yeon, Ramnath, Divya, Powell, Elizabeth E., Sweet, Matthew J., Roh, Yoon Seok, Hsin, I-Fang, Deng, Nan, Liu, Zhenqiu, Liang, Jiurong, Mena, Edward, Shouhed, Daniel, Schwabe, Robert F., Jiang, Dianhua, Lu, Shelly C., Noble, Paul W. and Seki, Ekihiro (2019) Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine, 11 496: . doi:10.1126/scitranslmed.aat9284
Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps
Chen, Kaiwen W., Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D., von Pein, Jessica B., Broz, Petr, Sweet, Matthew J. and Schroder, Kate (2018) Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science Immunology, 3 26: eaar6676. doi:10.1126/sciimmunol.aar6676
Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018) Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 14: . doi:10.1172/jci.insight.120274
Ramnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018) RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. Journal of Hepatology, 68 S1: S401-S402. doi:10.1016/s0168-8278(18)31040-7
The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair
Ramnath, Divya, Powell, Elizabeth E., Scholz, Glen M. and Sweet, Matthew J. (2016) The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell and Developmental Biology, 61 22-30. doi:10.1016/j.semcdb.2016.08.014
TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes
Ramnath, Divya, Tunny, Kathryn, Hohenhaus, Daniel M., Pitts, Claire M., Bergot, Anne-Sophie, Hogarth, P. Mark, Hamilton, John A., Kapetanovic, Ronan, Sturm, Richard A., Scholz, Glen M. and Sweet, Matthew J. (2015) TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes. Immunology and Cell Biology, 93 9: 771-779. doi:10.1038/icb.2015.77
Kwa, Mei Qi, Nguyen, Thao, Huynh, Jennifer, Ramnath, Divya, De Nardo, Dominic, Lam, Pei Yeng, Reynolds, Eric C., Hamilton, John A., Sweet, Matthew J. and Scholz, Glen M. (2014) Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry, 289 28: 19758-19768. doi:10.1074/jbc.M114.584540
Ramnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. In: International Liver Congress (ILC), Paris, France, (S401-S402). 11-15 April, 2018. doi:10.1016/S0168-8278(18)31040-7
Role of IRF6 in epithelial cell-mediated host defence and inflammation
Ramnath, Divya (2014). Role of IRF6 in epithelial cell-mediated host defence and inflammation PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi:10.14264/uql.2017.483
Defining molecular links between immune cell metabolism and inflammation
(2020–2023) NHMRC IDEAS Grants