Dr Trung Ngo

Honorary Senior Fellow

RECOVER Injury Research Centre
Faculty of Health and Behavioural Sciences

Overview

I completed a PhD in Neuroscience with Jack Pettigrew (FRS) at Vision, Touch & Hearing Research Centre followed by an NHMRC Clinical Research Fellowship at Alfred Health & Monash University.

Back in QLD I'm continuing a transdisciplinary research & innovation program to Bring Discoveries of the Brain to Life!

I'm currently focused on developing novel Biopharma Dx Tx Rx & Medical Technologies for enhancing human capabilities in performance, recovery & resilience with the following projects:

[1] Precision Pain Medicine — the largest genetic study of persistent (chronic) pain in Australia, in collaboration with QIMR Berghofer & Monash University, aims to identify pharmacogenomics causal pathways for the design of personalised therapeutics & effective early intervention approaches (e.g., screening, education, prevention).

[2] Brain Switcha — A digital transdiagnostic biomarker and cloud-based large-scale population phenotyping & analytics platform to improve early intervention strategies in sleep & mental health conditions (esp. at-risk youth cohorts) and recruitment screening for Defence forces.

[3] VCS — vestibulocortical stimulation: A simple, inexpensive, non-invasive & non-pharmacologic neurotherapeutic treatment technique for fibromyalgia (with US colleagues) and other centralised pain syndromes, sleep apnoea, dementia & mental health conditions (e.g., depression, PTSD, bipolar disorder).

I also have >5 years professional services experience in high-quality research metrics, engagement & impact analyses that successfully delivered several major strategic priorities to a wide client base: individual researchers, research groups, professional networks/associations, academic leaders/managers (e.g., Centre/School/Institute reviews & Annual Reports) through to senior executive business missions for national/international strategic partnerships. The service includes: research performance profiling & formal reports for grant applications/academic promotions; mapping capabilities, gaps & collaborations (e.g., clinical, corporate & government) across different research disciplines (e.g., patent/policy citations; external stakeholder engagement); ranking of funding applicants (e.g., ARC schemes); Government evaluations (e.g., ERA and Engagement & Impact assessments); workforce development (e.g., recruitment for senior leadership positions); and bibliometric benchmarks for University rankings.

In particular, I enjoy meeting & bringing people together with a shared vision & commitment to building diverse strategic partnerships that deliver meaningful solutions for society.

Research Interests

  • VCS — VestibuloCortical Stimulation: Applications & mechanisms
    — effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine — clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics'
  • Minimal phenotyping: Perceptual & cognitive biomarkers
    — validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts). — multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
  • Phylogenetics & evolution of bistable switching and VCS network
    — from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight) — investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine
  • MedTech & Biotech platform development
    — autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine — portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS.
  • Scientometrics of research benefits
    — developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Science with Honours Class Honours, The University of Queensland
  • Bachelor of Arts, The University of Queensland

Publications

View all Publications

Available Projects

  • The following research projects are open to enthusiastic & driven individuals from a wide range of background disciplines/industry experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics & statistics, biological/life sciences, medicine & allied health, information technology, psychology:

    Minimal phenotyping: Perceptual & cognitive biomarkers

    • validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).
    • multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    VCS — VestibuloCortical Stimulation: Applications & mechanisms

    • effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine
    • clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics'

    MedTech & Biotech platform development

    • autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine
    • portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS.

    Phylogenetics & evolution of bistable switching and VCS network

    • from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight)
    • investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine

    Scientometrics of research benefits

    • developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.

View all Available Projects

Publications

Featured Publications

Book Chapter

  • Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 211-252) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.09ngo

  • Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 77-108) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.04wad

Journal Article

Conference Publication

Other Outputs

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • The following research projects are open to enthusiastic & driven individuals from a wide range of background disciplines/industry experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics & statistics, biological/life sciences, medicine & allied health, information technology, psychology:

    Minimal phenotyping: Perceptual & cognitive biomarkers

    • validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).
    • multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    VCS — VestibuloCortical Stimulation: Applications & mechanisms

    • effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine
    • clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics'

    MedTech & Biotech platform development

    • autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine
    • portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS.

    Phylogenetics & evolution of bistable switching and VCS network

    • from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight)
    • investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine

    Scientometrics of research benefits

    • developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.