Dr Trung Ngo

Librarian

Learning and Research Services (University of Queensland Library)

Honorary Fellow

The University of Queensland Diamantina Institute
Faculty of Medicine
trung.ngo@uq.edu.au
+61 7 344 37976

Overview

I completed a PhD in Neuroscience (2009) with eminent Australian neurobiologist Jack Pettigrew (FRS). My research employed caloric vestibular stimulation (CVS) — a simple, non-invasive (unihemispheric) brain stimulation technique — to demonstrate evidence for a novel neural mechanism of visual rivalry: the interhemispheric switch (IHS) model.

I was awarded an NHMRC postdoctoral clinical research fellowship to continue investigating rivalry mechanisms and abnormalities in psychiatric groups. From 2010–2015 I was project coordinator and technology lead for this work at Monash Alfred Psychiatry Research Centre. My fellowship studies also examined CVS as a potential therapeutic intervention in persistent (chronic) pain disorders.

I am continuing this body of work with the following research projects:

[A] Validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).

[B] Effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric and neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) | #PrecisionPainMedicine

[C] Development of autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology and sleep medicine | #PrecisionSleepMedicine

[D] Phylogenetics and evolution of bistable switching — from bacterial chemotaxis and fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight) | #PrecisionSwitchMedicine

Research Interests

  • Minimal phenotyping: Perceptual and cognitive testing
    Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
  • Vestibulocortical stimulation: Applications and mechanisms
    Clinical applications of non-invasive repeated vestibulocortical stimulation (#rVCS) — and the genetics and neuroimaging of its therapeutic response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').
  • Biomedical device & software development
    Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibulocortical stimulation.
  • Phylogenetics & evolution of bistable switching and the vestibular system
    Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine
  • Scientometrics and research outcome measures
    Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using machine learning (A.I.) and large-scale data analysis algorithms.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Science with Honours Class Honours, The University of Queensland
  • Bachelor of Arts, The University of Queensland

Publications

View all Publications

Available Projects

  • The following research projects are open to keen and interested individuals from a wide range of background disciplines/professional experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics and statistics, biological/life sciences, medicine and allied health, information technology, psychology:

    Minimal phenotyping: Perceptual and cognitive testing

    • Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    Vestibulocortical stimulation (VCS): Applications and mechanisms

    • Clinical applications of non-invasive repeated vestibulocortical stimulation (rVCS) — and the genetics and neuroimaging of its therapeutic response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').

    Biomedical device & software development

    • Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibulocortical stimulation.

    Phylogenetics & evolution of bistable switching and the vestibular system

    • Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine

    Scientometrics and research outcome measures

    • Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using machine learning (A.I.) and large-scale data analysis algorithms.

View all Available Projects

Publications

Featured Publications

Book Chapter

  • Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 211-252) Amsterdam, The Netherlands: John Benjamins Publishing Company. doi:10.1075/aicr.90.09ngo

  • Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 77-108) Amsterdam, The Netherlands: John Benjamins Publishing Company. doi:10.1075/aicr.90.04wad

Journal Article

Conference Publication

Other Outputs

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • The following research projects are open to keen and interested individuals from a wide range of background disciplines/professional experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics and statistics, biological/life sciences, medicine and allied health, information technology, psychology:

    Minimal phenotyping: Perceptual and cognitive testing

    • Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    Vestibulocortical stimulation (VCS): Applications and mechanisms

    • Clinical applications of non-invasive repeated vestibulocortical stimulation (rVCS) — and the genetics and neuroimaging of its therapeutic response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').

    Biomedical device & software development

    • Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibulocortical stimulation.

    Phylogenetics & evolution of bistable switching and the vestibular system

    • Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine

    Scientometrics and research outcome measures

    • Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using machine learning (A.I.) and large-scale data analysis algorithms.