Journal Article: SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice
Alhammad, Yousef M., Parthasarathy, Srivatsan, Ghimire, Roshan, Kerr, Catherine M., O’Connor, Joseph J., Pfannenstiel, Jessica J., Chanda, Debarati, Miller, Caden A., Baumlin, Nathalie, Salathe, Matthias, Unckless, Robert L., Zuñiga, Sonia, Enjuanes, Luis, More, Sunil, Channappanavar, Rudragouda and Fehr, Anthony R. (2023). SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Proceedings of the National Academy of Sciences, 120 (35) e2302083120, 1-11. doi: 10.1073/pnas.2302083120
Journal Article: Full-length genome of the equine influenza A virus subtype H3N8 from 2019 outbreak in Saudi Arabia
Alaql, Fanan A., Alhafufi, Ali N., Kasem, Samy, Alhammad, Yousef M. O., Albaqshi, Hassan, Alyousaf, Ameen, Alsubaie, Faisal M., Alghamdi, Ahmed N., Abdel-Moneim, Ahmed S. and Alharbi, Sulaiman A. (2022). Full-length genome of the equine influenza A virus subtype H3N8 from 2019 outbreak in Saudi Arabia. Animals, 12 (19) 2720, 1-13. doi: 10.3390/ani12192720
Journal Article: Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening
Roy, Anu, Alhammad, Yousef M., McDonald, Peter, Johnson, David K., Zhuo, Junlin, Wazir, Sarah, Ferraris, Dana, Lehtiö, Lari, Leung, Anthony K.L. and Fehr, Anthony R. (2022). Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening. Antiviral Research, 203 105344, 105344. doi: 10.1016/j.antiviral.2022.105344
Predicting and preparing for the unfolding evolution of SARS-CoV-2
Doctor Philosophy
Alhammad, Yousef M., Parthasarathy, Srivatsan, Ghimire, Roshan, Kerr, Catherine M., O’Connor, Joseph J., Pfannenstiel, Jessica J., Chanda, Debarati, Miller, Caden A., Baumlin, Nathalie, Salathe, Matthias, Unckless, Robert L., Zuñiga, Sonia, Enjuanes, Luis, More, Sunil, Channappanavar, Rudragouda and Fehr, Anthony R. (2023). SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Proceedings of the National Academy of Sciences, 120 (35) e2302083120, 1-11. doi: 10.1073/pnas.2302083120
Full-length genome of the equine influenza A virus subtype H3N8 from 2019 outbreak in Saudi Arabia
Alaql, Fanan A., Alhafufi, Ali N., Kasem, Samy, Alhammad, Yousef M. O., Albaqshi, Hassan, Alyousaf, Ameen, Alsubaie, Faisal M., Alghamdi, Ahmed N., Abdel-Moneim, Ahmed S. and Alharbi, Sulaiman A. (2022). Full-length genome of the equine influenza A virus subtype H3N8 from 2019 outbreak in Saudi Arabia. Animals, 12 (19) 2720, 1-13. doi: 10.3390/ani12192720
Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening
Roy, Anu, Alhammad, Yousef M., McDonald, Peter, Johnson, David K., Zhuo, Junlin, Wazir, Sarah, Ferraris, Dana, Lehtiö, Lari, Leung, Anthony K.L. and Fehr, Anthony R. (2022). Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening. Antiviral Research, 203 105344, 105344. doi: 10.1016/j.antiviral.2022.105344
Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R. and Brenner, Charles (2020). Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. Journal of Biological Chemistry, 295 (52), 17986-17996. doi: 10.1074/jbc.ra120.015138
The viral macrodomain counters host antiviral ADP-Ribosylation
Alhammad, Yousef M. O. and Fehr, Anthony R. (2020). The viral macrodomain counters host antiviral ADP-Ribosylation. Viruses, 12 (4) 384. doi: 10.3390/v12040384
Gu, Jun, Hardy, Joshua, Boo, Irene, Vietheer, Patricia, McCaffrey, Kathleen, Alhammad, Yousef, Chopra, Abha, Gaudieri, Silvana, Poumbourios, Pantelis, Coulibaly, Fasséli and Drummer, Heidi E. (2018). Escape of hepatitis C virus from epitope I neutralization increases sensitivity of other neutralization epitopes. Journal of Virology, 92 (9) e02066-17, 1-18. doi: 10.1128/jvi.02066-17
Alhammad, Yousef, Gu, Jun, Boo, Irene, Harrison, David, McCaffrey, Kathleen, Vietheer, Patricia T., Edwards, Stirling, Quinn, Charles, Coulibaly, Fásseli, Poumbourios, Pantelis and Drummer, Heidi E. (2015). Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region. Journal of Virology, 89 (24), 12245-12261. doi: 10.1128/jvi.02070-15
Alhammad, Yousef M. O., Maharajh, Sanvir, Butcher, Rebecca, Eden, John-Sebastian, White, Peter A., Poumbourios, Pantelis and Drummer, Heidi E (2015). Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection. PLOS ONE, 10 (5) ARTN e0126397, e0126397. doi: 10.1371/journal.pone.0126397
Predicting and preparing for the unfolding evolution of SARS-CoV-2
Doctor Philosophy — Associate Advisor
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