Journal Article: Patient-level meta-analysis of low-dose hydrocortisone in adults with septic shock
Pirracchio, Romain, Annane, Djillali, Waschka, Andre K., Lamontagne, François, Arabi, Yaseen M., Bollaert, Pierre-Edouard, Billot, Laurent, Du, Bin, Briegel, Josef, Cohen, Jeremy, Finfer, Simon, Gordon, Anthony, Hammond, Naomi, Hyvernat, Herve, Keh, Didier, Li, Yi, Liu, Ling, Meduri, Gianfranco Umberto, Mirea, Liliana, Myburgh, John A., Sprung, Charles L., Tilouche, Neijla, Tongyoo, Surat, Venkatesh, Balasubramanian, Zheng, Ruiqiang and Delaney, Anthony (2023). Patient-level meta-analysis of low-dose hydrocortisone in adults with septic shock. NEJM Evidence, 2 (6), 1-12. doi: 10.1056/evidoa2300034
Journal Article: The need for an Australasian burns critical care standardised data collection tool
Holley, Anthony, Droder, Brett, Reade, Michael, Lipman, Jeffrey, Pilcher, David, Litton, Edward, Karamujic, Nermin, Laupland, Kevin, Vallmuur, Kirsten, Delaney, Anthony and Cohen, Jeremy (2021). The need for an Australasian burns critical care standardised data collection tool. Critical Care and Resuscitation, 23 (4), 361-363. doi: 10.51893/2021.4.POV
Journal Article: Long-term costs and cost-effectiveness of adjunctive corticosteroids for patients with septic shock in New Zealand
Thompson, Kelly J., Young, Paul J., Venkatesh, Balasubramanian, Cohen, Jeremy, Finfer, Simon R., Grattan, Sarah, Hammond, Naomi E., Jan, Stephen, Li, Qiang, Di Tanna, Gian Luca, McArthur, Colin, Myburgh, John, Rajbhandari, Dorrilyn and Taylor, Colman B. (2021). Long-term costs and cost-effectiveness of adjunctive corticosteroids for patients with septic shock in New Zealand. Australian Critical Care, 35 (3), 241-250. doi: 10.1016/j.aucc.2021.05.006
Vascular responsiveness in septic shock (NHMRC Project Grant led by UNSW)
(2019–2022) University of New South Wales
(2018–2023) Intensive Care Foundation
Enhancing host defence mechanisms in severe bacterial infections
(2018–2020) NHMRC Project Grant
Bacteria-induced WNT responses and their role in infection-associated inflammation
(2023) Doctor Philosophy
(2021) Doctor Philosophy
Critical care management of burns patients
Doctor Philosophy
Venkatesh, Bala and Cohen, Jeremy (2016). Adrenal insufficiency. Surgical intensive care medicine. (pp. 507-515) edited by John M. O’Donnell and Flávio E. Nácul. Cham, Switzerland: Springer . doi: 10.1007/978-3-319-19668-8_37
Glutamine supplementation in multiple trauma of critical care
Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy and Banks, Merrilyn (2015). Glutamine supplementation in multiple trauma of critical care. Diet and nutrition in critical care. (pp. 203-218) edited by Rajkumar Rajendram, Victor R. Preedy and Vinood B. Patel. New York, NY, United States: Springer New York. doi: 10.1007/978-1-4614-7836-2_141
Glutamine supplementation in multiple trauma patients
Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy and Banks, Merrilyn (2015). Glutamine supplementation in multiple trauma patients. Glutamine in Clinical Nutrition. (pp. 181-194) edited by Rajkumar Rajendram, Victor R. Preedy and Vinood B. Patel. New York, United States: Springer. doi: 10.1007/978-1-4939-1932-1_14
Pathophysiology and management of hypo- and hyperadrenalism
Cohen, Jeremy and Venkatesh, Balasubramanian (2012). Pathophysiology and management of hypo- and hyperadrenalism. The Oxford textbook of critical care. (pp. 28-34) edited by A. J. Webb, M. J. Shapiro, M. Singer and P. M. Suter. Oxford, United Kingdom: Oxford University Press.
Venkatesh, Bala and Cohen, Jeremy (2010). Adrenal Insufficiency. Surgical intensive care medicine. (pp. 399-406) New York: Springer. doi: 10.1007/978-0-387-77893-8_36
Adrenocortical insufficiency in critical illness
Venkatesh, B. and Cohen, J. (2008). Adrenocortical insufficiency in critical illness. Oh's Intensive Care Manual. (pp. 647-652) edited by Bersten, A. D. and Soni, N.. United States of America: Elsevier Limited.
Cortisol metabolism in inflammation and sepsis
Venkatesh, B. and Cohen, J. (2008). Cortisol metabolism in inflammation and sepsis. Yearbook of Intensive Care and Emergency Medicine 2008. (pp. 514-518) edited by J.-L. Vincent. Heidelberg: Springer - Verlag.
Cohen, Jeremy and Lipman, Jeffrey (2008). Use and abuse of antibiotics. Anaesthesia science. (pp. 128-136) edited by Nigel R. Webster and Helen F. Galley. Malden, MA, United States: Blackwell Publishing . doi: 10.1002/9780470755297.ch10
Plasma cortisol: Time to look deeeper?
Cohen, J., Prins, J. and Venkatesh, B. (2007). Plasma cortisol: Time to look deeeper?. 2007 Yearbook of Intensive Care and Emergency Medicine. (pp. 106-112) edited by J. L. Vincent. Berlin; Heidelberg, Germany: Springer-Verlag. doi: 10.1007/978-0-387-49518-7_11
Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy
Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-159) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin & Heidelberg, Germany; New York, USA: Springer - Verlag.
Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy
Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-158) Berlin, Germany: Springer. doi: 10.1007/978-3-540-34406-3_13
Cohen, Jeremy and Lipman, Jeffrey (2006). Use and Abuse of antibiotics. Anesthesia science. (pp. 128-139) edited by Nigel R. Webster and Helen F. Galley. Malden, Mass.: Blackwell Pub.
Patient-level meta-analysis of low-dose hydrocortisone in adults with septic shock
Pirracchio, Romain, Annane, Djillali, Waschka, Andre K., Lamontagne, François, Arabi, Yaseen M., Bollaert, Pierre-Edouard, Billot, Laurent, Du, Bin, Briegel, Josef, Cohen, Jeremy, Finfer, Simon, Gordon, Anthony, Hammond, Naomi, Hyvernat, Herve, Keh, Didier, Li, Yi, Liu, Ling, Meduri, Gianfranco Umberto, Mirea, Liliana, Myburgh, John A., Sprung, Charles L., Tilouche, Neijla, Tongyoo, Surat, Venkatesh, Balasubramanian, Zheng, Ruiqiang and Delaney, Anthony (2023). Patient-level meta-analysis of low-dose hydrocortisone in adults with septic shock. NEJM Evidence, 2 (6), 1-12. doi: 10.1056/evidoa2300034
The need for an Australasian burns critical care standardised data collection tool
Holley, Anthony, Droder, Brett, Reade, Michael, Lipman, Jeffrey, Pilcher, David, Litton, Edward, Karamujic, Nermin, Laupland, Kevin, Vallmuur, Kirsten, Delaney, Anthony and Cohen, Jeremy (2021). The need for an Australasian burns critical care standardised data collection tool. Critical Care and Resuscitation, 23 (4), 361-363. doi: 10.51893/2021.4.POV
Thompson, Kelly J., Young, Paul J., Venkatesh, Balasubramanian, Cohen, Jeremy, Finfer, Simon R., Grattan, Sarah, Hammond, Naomi E., Jan, Stephen, Li, Qiang, Di Tanna, Gian Luca, McArthur, Colin, Myburgh, John, Rajbhandari, Dorrilyn and Taylor, Colman B. (2021). Long-term costs and cost-effectiveness of adjunctive corticosteroids for patients with septic shock in New Zealand. Australian Critical Care, 35 (3), 241-250. doi: 10.1016/j.aucc.2021.05.006
Cohen, Jeremy, Blumenthal, Antje, Cuellar-Partida, Gabriel, Evans, David M., Finfer, Simon, Li, Qiang, Ljungberg, Johanna, Myburgh, John, Peach, Elizabeth, Powell, Joseph, Rajbhandari, Dorrilyn, Rhodes, Andrew, Senabouth, Anne and Venkatesh, Balasubramanian (2021). The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock. Intensive Care Medicine, 47 (9), 974-983. doi: 10.1007/s00134-021-06464-5
Hammond, Naomi E., Kumar, Ashwani, Vijayaraghavan, Bharath Kumar Tirupakuzhi, Arabi, Yaseen M., Cohen, Jeremy, Di Tanna, Gian Luca, Grattan, Sarah, van Heerden, Vernon, Joynt, Gavin, Machado, Flavia R., Perner, Anders, Rhodes, Andrew, Yeh, Tony and Venkatesh, Balasubramanian (2021). Clinician preferences for prescription of corticosteroids in patients with septic shock: an international survey. Critical Care and Resuscitation, 23 (2), 234-238. doi: 10.51893/2021.2.s1
Cohen, Jeremy, Delaney, Anthony, Anstey, James, Anstey, Matthew, Barge, Deborah, Bellomo, Rinaldo, Bhardwa, Vishnu, Brinkerhoff, Gail, Board, Jasmin, Campain, Anna, Cooper, D James, Di Tanna, Gian Luca, Finnis, Mark, Fitzgerald, Emily, Flower, Oliver, Healey, Paul, Hunt, Anna, Lawrence, Cassie, Merthens, Jan, Newby, Lynette, Pearson, David, Raith, Eamon, Robertson, Yvonne, Schweikert, Sacha, Starr, Therese, Tallott, Mandy, van der Poll, Andrew, Young, Paul and Udy, Andrew (2021). Dysnatremia and 6-month functional outcomes in critically ill patients with aneurysmal subarachnoid hemorrhage: a prospective cohort study. Critical Care Explorations, 3 (6), e0445. doi: 10.1097/cce.0000000000000445
Dhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj and Roberts, Jason A. (2021). Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study. International Journal of Antimicrobial Agents, 57 (2) 106232, 106232. doi: 10.1016/j.ijantimicag.2020.106232
Sex differences in response to adjunctive corticosteroid treatment for patients with septic shock
Thompson, Kelly, Venkatesh, Balasubramanian, Hammond, Naomi, Taylor, Colman, Finfer, Simon, Bompoint, Severine, Carcel, Cheryl, Cohen, Jeremy, Jan, Stephen, Myburgh, John, Peters, Sanne A. E. and Rajbhandari, Dorrilyn (2021). Sex differences in response to adjunctive corticosteroid treatment for patients with septic shock. Intensive Care Medicine, 47 (2), 246-248. doi: 10.1007/s00134-020-06325-7
Annane, Djillali, Pirracchio, Romain, Billot, Laurent, Waschka, Andre, Chevret, Sylvie, Cohen, Jeremy, Finfer, Simon, Gordon, Anthony, Hammond, Naomi, Myburgh, John, Venkatesh, Balasubramanian, Delaney, Anthony and ULYSSES IPDMA Collaborators (2020). Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data. BMJ Open, 10 (12) e040931, e040931. doi: 10.1136/bmjopen-2020-040931
Ingelfinger imperative: when speed of release risks quality of research
Fanning, Jonathon P., Cohen, Jeremy and Venkatesh, Balasubramanian (2020). Ingelfinger imperative: when speed of release risks quality of research. Internal Medicine Journal, 50 (12), 1595-1596. doi: 10.1111/imj.15047
Udy, Andrew, The PROMOTE-SAH Investigators and Cohen, Jeremy (2020). Six-month mortality and functional outcomes in aneurysmal sub-arachnoid haemorrhage patients admitted to intensive care units in Australia and New Zealand: A prospective cohort study. Journal of Clinical Neuroscience, 80, 92-99. doi: 10.1016/j.jocn.2020.07.049
Cohen, Jeremy, Bellomo, Rinaldo, Billot, Laurent, Burrell, Louise M., Evans, David M., Finfer, Simon, Hammond, Naomi E., Li, Qiang, Liu, David, McArthur, Colin, McWhinney, Brett, Moore, John, Myburgh, John, Peake, Sandra, Pretorius, Carel, Rajbhandari, Dorrilyn, Rhodes, Andrew, Saxena, Manoj, Ungerer, Jacobus P. J., Young, Morag J. and Venkatesh, Balasubramanian (2020). Plasma cortisol, aldosterone, and ascorbic acid concentrations in patients with septic shock do not predict treatment effect of hydrocortisone on mortality. A nested cohort study. American Journal of Respiratory and Critical Care Medicine, 202 (5), 700-707. doi: 10.1164/rccm.202002-0281OC
The cost-effectiveness of adjunctive corticosteroids for patients with septic shock
Thompson, Kelly J., Taylor, Colman B., Venkatesh, Balasubramanian, Cohen, Jeremy, Hammond, Naomi E., Jan, Stephen, Li, Qiang, Myburgh, John, Rajbhandari, Dorrilyn, Saxena, Manoj, Kumar, Ashwani, Finfer, Simon R. and The ADRENAL Management Committee and Investigators and the ANZICS Clinical Trials Group (2020). The cost-effectiveness of adjunctive corticosteroids for patients with septic shock. Critical Care and Resuscitation, 22 (3), 191-199.
Mineralocorticoid dysfunction during critical illness: a review of the evidence
Nethathe, Gladness Dakalo, Cohen, Jeremy, Lipman, Jeffrey, Anderson, Ronald and Feldman, Charles (2020). Mineralocorticoid dysfunction during critical illness: a review of the evidence. Anesthesiology, 133 (2), 439-457. doi: 10.1097/ALN.0000000000003365
Septic shock: a genomewide association study and polygenic risk score analysis
D'Urso, Shannon, Rajbhandari, Dorrilyn, Peach, Elizabeth, De Guzman, Erika, Li, Qiang, Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Ligthart, Symen, Brown, Matthew A., Powell, Joseph, McArthur, Colin, Rhodes, Andrew, Meyer, Jason, Finfer, Simon, Myburgh, John, Blumenthal, Antje, Cohen, Jeremy, Venkatesh, Balasubramanian, Cuellar-Partida, Gabriel and Evans, David M. (2020). Septic shock: a genomewide association study and polygenic risk score analysis. Twin Research and Human Genetics, 23 (4), 204-213. doi: 10.1017/thg.2020.60
Hammond, Naomi E., Finfer, Simon R., Li, Qiang, Taylor, Colman, Cohen, Jeremy, Arabi, Yaseen, Bellomo, Rinaldo, Billot, Laurent, Harward, Meg, Joyce, Christopher, McArthur, Colin, Myburgh, John, Perner, Anders, Rajbhandari, Dorrilyn, Rhodes, Andrew, Thompson, Kelly, Webb, Steve and Venkatesh, Balasubramanian (2020). Health-related quality of life in survivors of septic shock: 6-month follow-up from the ADRENAL trial. Intensive Care Medicine, 46 (9), 1696-1706. doi: 10.1007/s00134-020-06169-1
Lee, J., Eley, V. A., Wyssusek, K. H., Kimble, R. M. N., Way, M., Coonan, E., Cohen, J., Rowell, J. and van Zundert, A. A. (2020). Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy labouring women: a prospective observational study. BJOG, 127 (7), 820-827. doi: 10.1111/1471-0528.16094
Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey and Cohen, Jeremy (2020). There is no fire without smoke! Pathophysiology and treatment of inhalational injury in burns: a narrative review. Anaesthesia and Intensive Care, 48 (2), 0310057X2091328-122. doi: 10.1177/0310057x20913282
Holley, Anthony, Cohen, Jeremy, Reade, Michael, Laupland, Kevin B. and Lipman, Jeffrey (2020). New guidelines for the management of severe thermal burns in the acute phase in adults and children: Is it time for a global surviving burn injury campaign (SBIC)?. Anaesthesia Critical Care and Pain Medicine, 39 (2), 195-196. doi: 10.1016/j.accpm.2020.03.009
Lee, Julie, Eley, Victoria A., Wyssusek, Kerstin H., Kimble, Rebecca M.N., Way, Mandy, Cohen, Jeremy and van Zundert, André A. (2020). The influence of obesity on coagulation in healthy term pregnancy as assessed by rotational thromboelastometry. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 (5) ajo.13141, 714-719. doi: 10.1111/ajo.13141
Lee, J., Wyssusek, K. H., Kimble, R. M.N., Way, M., van Zundert, A. A., Cohen, J., Rowell, J. and Eley, V. A. (2020). Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy pregnant Australian women: a comparison of labouring and non-labouring women at term. International Journal of Obstetric Anesthesia, 41, 7-13. doi: 10.1016/j.ijoa.2019.10.003
Venkatesh, Balasubramanian, Finfer, Simon, Cohen, Jeremy, Rajbhandari, Dorrilyn, Arabi, Yaseen, Bellomo, Rinaldo, Billot, Laurent, Glass, Parisa, Joyce, Christopher, Li, Qiang, McArthur, Colin, Perner, Anders, Rhodes, Andrew, Thompson, Kelly, Webb, Steve and Myburgh, John (2019). Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria A Post Hoc Analysis of the ADRENAL Trial. Anesthesiology, 131 (6), 1292-1300. doi: 10.1097/ALN.0000000000002955
Survey of critical care practice in Australian and New Zealand burn referral centres
Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey, Delaney, Anthony, Udy, Andrew, Lee, Richard, Litton, Edward, Cheung, Winston, Turner, Andrew, Garside, Tessa, Macken, Lewis, Reddi, Benjamin, Kol, Mark, Kazemi, Alex, Shah, Asim, Townsend, Shane and Cohen, Jeremy (2019). Survey of critical care practice in Australian and New Zealand burn referral centres. Critical Care and Resuscitation, 21 (4), 303-304.
Venkatesh, Balasubramanian and Cohen, Jeremy (2019). The authors reply. Critical Care Medicine, 47 (12), e1035-e1036. doi: 10.1097/CCM.0000000000004014
Venkatesh, Balasubramanian and Cohen, Jeremy (2019). Why the Adjunctive Corticosteroid Treatment in Critically Ill Patients With Septic Shock (ADRENAL) Trial Did Not Show a Difference in Mortality. Critical Care Medicine, 47 (12), 1785-1788. doi: 10.1097/CCM.0000000000003834
Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752
Lee, J., Eley, V. A., Wyssusek, K. H., Coonan, E., Way, M., Cohen, J., Rowell, J. and van Zundert, A. A. (2019). Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy women undergoing elective caesarean delivery: A prospective observational study in Australia. International Journal of Obstetric Anesthesia, 38, 10-18. doi: 10.1016/j.ijoa.2019.01.008
Steroids and Sepsis: the Debate Continues
Ramanan, Mahesh, Cohen, Jeremy and Venkatesh, Balasubramanian (2019). Steroids and Sepsis: the Debate Continues. International Anesthesiology Clinics, 57 (2), 17-30. doi: 10.1097/AIA.0000000000000220
Adjunctive corticosteroid treatment in septic shock
Cohen, Jeremy and Venkatesh, Balasubramanian (2019). Adjunctive corticosteroid treatment in septic shock. Anesthesiology, 131 (2), 410-419. doi: 10.1097/ALN.0000000000002604
Hydrocortisone in Vasodilatory Shock
Venkatesh, Balasubramanian and Cohen, Jeremy (2019). Hydrocortisone in Vasodilatory Shock. Critical Care Clinics, 35 (2), 263-275. doi: 10.1016/j.ccc.2018.11.005
Less is more: catecholamine-sparing strategies in septic shock
Venkatesh, Balasubramanian, Khanna, Ashish K. and Cohen, Jeremy (2019). Less is more: catecholamine-sparing strategies in septic shock. Intensive Care Medicine, 45 (12), 1810-1812. doi: 10.1007/s00134-019-05770-3
Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7
Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003
Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006
Rygård, Sofie Louise, Butler, Ethan, Granholm, Anders, Møller, Morten Hylander, Cohen, Jeremy, Finfer, Simon, Perner, Anders, Myburgh, John, Venkatesh, Balasubramanian and Delaney, Anthony (2018). Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis. Intensive Care Medicine, 44 (7), 1003-1016. doi: 10.1007/s00134-018-5197-6
Long-term outcomes of the ADRENAL trial
Venkatesh, Balasubramanian, Finfer, Simon, Myburgh, John, Cohen, Jeremy and Billot, Laurent (2018). Long-term outcomes of the ADRENAL trial. The New England Journal of Medicine, 378 (18), 1744-1745. doi: 10.1056/NEJMc1803563
Adjunctive glucocorticoid therapy in patients with septic shock
Venkatesh, Balasubramanian, Finfer, Simon, Cohen, Jeremy, Rajbhandari, Dorrilyn, Arabi, Yaseen, Bellomo, Rinaldo, Billot, Laurent, Correa, Maryam, Glass, Parisa, Harward, Meg, Joyce, Christopher, Li, Qiang, McArthur, Colin, Perner, Anders, Rhodes, Andrew, Thompson, Kelly, Webb, Steve, Myburgh, John and ADRENAL Trial Investigators and the Australian–New Zealand Intensive Care Society Clinical Trials Group (2018). Adjunctive glucocorticoid therapy in patients with septic shock. The New England journal of medicine, 378 (9), 797-808. doi: 10.1056/NEJMoa1705835
Gatica-Andrades, Marcela, Vagenas, Dimitrios, Kling, Jessica, Nguyen, Tam T. K., Benham, Helen, Thomas, Ranjeny, Korner, Heinrich, Venkatesh, Bala, Cohen, Jeremy and Blumenthal, Antje (2017). WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice. Blood Advances, 1 (16), 1274-1286. doi: 10.1182/bloodadvances.2017006163
Udy, Andrew A., Schweikert, Sacha, Anstey, James, Anstey, Matthew, Cohen, Jeremy, Flower, Oliver, Saxby, Edward, van der Poll, Andrew and Delaney, Anthony (2017). Critical care management of aneurysmal subarachnoid haemorrhage in Australia and New Zealand: what are we doing, and where to from here?. Critical Care and Resuscitation, 19 (2), 103-109.
Billot, Laurent, Venkatesh, Balasubramanian, Myburgh, John, Finfer, Simon, Cohen, Jeremy, Webb, Steve, McArthur, Colin, Joyce, Christopher, Bellomo, Rinaldo, Rhodes, Andrew, Perner, Anders, Arabi, Yaseen, Rajbhandari, Dorrilyn, Glass, Parisa, Thompson, Kelly, Correa, Maryam and Harward, Meg (2017). Statistical analysis plan for the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock (ADRENAL) trial. Critical Care and Resuscitation, 19 (2), 183-191.
Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
Winearls, James, Wullschleger, Martin, Wake, Elizabeth, Hurn, Catherine, Furyk, Jeremy, Ryan, Glenn, Trout, Melita, Walsham, James, Holley, Anthony, Cohen, Jeremy, Shuttleworth, Megan, Dyer, Wayne, Keijzers, Gerben, Fraser, John F., Presneill, Jeffrey and Campbell, Don (2017). Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial. Trials, 18 (1) 241, 241. doi: 10.1186/s13063-017-1980-x
Udy, Andrew A., Vladic, Chelsey, Saxby, Edward Robert, Cohen, Jeremy, Delaney, Anthony, Flower, Oliver, Anstey, Matthew, Bellomo, Rinaldo, Cooper, David James and Pilcher, David V. (2017). Subarachnoid hemorrhage patients admitted to intensive care in Australia and New Zealand: a multicenter cohort analysis of in-hospital mortality over 15 years. Critical Care Medicine, 45 (2), e135-e145. doi: 10.1097/CCM.0000000000002059
Rotational thromboelastometry (ROTEM®) in obstetrics
Lee, Julie, Wyssusek, Kerstin, Cohen, Jeremy and van Zundert, Andre (2017). Rotational thromboelastometry (ROTEM®) in obstetrics. Australasian Anaesthesia Blue Book, 95-103.
Fundamentals of aerosol therapy in critical care
Dhanani, Jayesh, Fraser, John F., Chan, Hak-Kim, Rello, Jordi, Cohen, Jeremy and Roberts, Jason A. (2016). Fundamentals of aerosol therapy in critical care. Critical Care, 20 (1) 269, 269. doi: 10.1186/s13054-016-1448-5
Cohen, Jeremy, Pretorius, Carel J., Ungerer, Jacobus P. J., Cardinal, John, Blumenthal, Antje, Presneill, Jeff, Gatica-Andrades, Marcela, Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Dunlop, Rachel, Starr, Therese and Venkatesh, Bala (2016). Glucocorticoid sensitivity is highly variable in critically ill patients with septic shock and is associated with disease severity. Critical Care Medicine, 44 (6), 1034-1041. doi: 10.1097/CCM.0000000000001633
Ridgeon, Elliott, Bellomo, Rinaldo, Myburgh, John, Saxena, Manoj, Weatherall, Mark, Jahan, Rahi, Arawwawala, Dilshan, Bell, Stephanie, Butt, Warwick, Camsooksai, Julie, Carle, Coralie, Cheng, Andrew, Cirstea, Emanuel, Cohen, Jeremy, Cranshaw, Julius, Delaney, Anthony, Eastwood, Glenn, Eliott, Suzanne, Franke, Uwe, Gantner, Dashiell, Green, Cameron, Howard-Griffin, Richard, Inskip, Deborah, Litton, Edward, MacIsaac, Christopher, McCairn, Amanda, Mahambrey, Tushar, Moondi, Parvez, Newby, Lynette ... Young, Paul (2016). Validation of a classification system for causes of death in critical care: an assessment of inter-rater reliability. Critical Care and Resuscitation, 18 (1), 50-54.
Conway, Paul, Pretorius, Carel J, Ungerer, Jacobus P. J., Lassig-Smith, Melissa, Stuart, Janine, Jarrett, Paul, Starr, Therese, Dunlop, Rachael, Venkatesh, Bala and Cohen, Jeremy (2015). Cortisol responses at baseline and after corticotropin in acute aneurysmal subarachnoid haemorrhage: a prospective study. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 17 (1), 37-42.
Venkatesh, Balasubramanian and Cohen, Jeremy (2015). The utility of the corticotropin test to diagnose adrenal insufficiency in critical illness: An update. Clinical Endocrinology, 83 (3), 289-297. doi: 10.1111/cen.12702
Ten false beliefs about cortisol in critically ill patients
Venkatesh, Balasubramanian, Cohen, Jeremy and Cooper, Mark (2015). Ten false beliefs about cortisol in critically ill patients. Intensive Care Medicine, 41 (10), 1817-1819. doi: 10.1007/s00134-014-3635-7
Venkatesh, Balasubramanian, Imeson, Lee, Kruger, Peter, Cohen, Jeremy, Jones, Mark and Bellomo, Rinaldo (2014). Elevated plasma free cortisol concentrations and ratios are associated with increased mortality even in the presence of statin therapy in patients with severe sepsis. Critical Care Medicine, 43 (3), 630-635. doi: 10.1097/CCM.0000000000000750
Venkatesh, Bala, Myburgh, John, Finfer, Simon, Webb, Steve A. R., Cohen, Jeremy, Bellomo, Rinaldo, McArthur, Colin, Joyce, Christopher J., Rajbhandari, Dorrilyn, Glass, Parisa, Harward, Meg and The ANZICS CTG investigators (2013). The ADRENAL study protocol: ADjunctive corticosteroid tREatment iN criticAlly ilL patients with septic shock. Critical Care and Resuscitation, 15 (2), 83-88.
Cohen, Jeremy, Venkatesh, Bala and Tan, Terrence (2013). Comparison of the diagnostic accuracy of measured and calculated free cortisol in acutely ill patients using the Coolens equation. Critical Care and Resuscitation, 15 (1), 39-41.
Semark, Andrew J., Venkatesh, Karthik, McWhinney, Brett C., Pretorius, Carel, Roberts, Jason A., Cohen, Jeremy and Venkatesh, Bala (2013). The compatibility of a low concentration of hydrocortisone sodium succinate with selected drugs during a simulated Y-site administration. Critical Care and Resuscitation, 15 (1), 63-66.
Dismissal of the utility of free cortisol measurement is premature
Cohen, Jeremy, Pretorius, Carel and Venkatesh, Bala (2012). Dismissal of the utility of free cortisol measurement is premature. Intensive Care Medicine, 38 (4), 718-718. doi: 10.1007/s00134-012-2505-4
Cohen, Jeremy, Lassig Smith, Melissa, Deans, Renae V., Pretorius, Carel J., Ungerer, Jacobus P. J., Tan, Terrence, Jones, Mark and Venkatesh, Bala (2012). Serial changes in plasma total cortisol, plasma free cortisol and tissue cortisol activity in patients with septic shock: An observational study. Shock, 37 (1), 28-33. doi: 10.1097/SHK.0b013e318239b809
Adrenocortical (dys)function in septic shock – A sick eudrenal state
Venkatesh, Balasubramanian and Cohen, Jeremy (2011). Adrenocortical (dys)function in septic shock – A sick eudrenal state. Best Practice and Research Clinical Endocrinology and Metabolism, 25 (5), 719-733. doi: 10.1016/j.beem.2011.04.007
Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy, Banks, Merrilyn, Dulhunty, Joel, Roberts, Jason A. and Lipman, Jeffrey (2011). Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial. BMJ Open, 1 (2) e000334, 1-8. doi: 10.1136/bmjopen-2011-000334
Tan, Terrence, Chang, Linus, Woodward, Aidan, McWhinney, Brett, Galligan, John, Macdonald, Graeme A., Cohen, Jeremy and Venkatesh, Bala (2010). Characterising adrenal function using directly measured plasma free cortisol in stable severe liver disease. Journal of Hepatology, 53 (5), 841-848. doi: 10.1016/j.jhep.2010.05.020
Cohen, J and Venkatesh, B (2010). Relative adrenal insufficiency in the intensive care population; background and critical appraisal of the evidence. Anaesthesia and Intensive Care, 38 (3), 425-436. doi: 10.1177/0310057x1003800304
When an effect is unclear, questioning its proposed mechanism is appropriate
Cohen, Jeremy and Venkatesh, Balasubramanian (2010). When an effect is unclear, questioning its proposed mechanism is appropriate. Critical Care and Resuscitation, 12 (1), 68-68. doi: 10.1016/S1441-2772(23)01362-5
Assessment of Tissue Cortisol Activity
Cohen, Jeremy and Venkatesh, Bala (2009). Assessment of Tissue Cortisol Activity. Critical Care and Resuscitation, 11 (4), 287-289.
Sick adrenal or sick euadrenal?
Venkatesh, Bala and Cohen, Jeremy (2009). Sick adrenal or sick euadrenal?. Critical Care and Resuscitation, 11 (4), 301-304.
Changes in serum adiponectin concentrations in critical illness: a preliminary investigation
Venkatesh, Bala, Hickman, Ingrid, Nisbet, Janelle, Cohen, Jeremy and Prins, John (2009). Changes in serum adiponectin concentrations in critical illness: a preliminary investigation. Critical Care, 13 (4) R105, R105.1-R105.5. doi: 10.1186/cc7941
Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation
Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6), xx-xx. doi: 10.1186/cc8184
Foot, Carole, Host, Daniel, Campher, Dylan, Tomczak, Lucas, Ziegenfuss, Marc, Cohen, Jeremy and Nunnink, Leo (2008). Moulage in high-fidelity simulation-A chest wall burn escharotomy model for visual realism and as an educational tool. Simulation in Healthcare, 3 (3; Fall), 183-185. doi: 10.1097/SIH.0b013e318184260f
Evidence of altered cortisol metabolism in critically ill patients: a prospective study
Venkatesh, Bala, Cohen, Jeremy, Hickman, Ingrid, Nisbet, Janelle, Thomas, Peter, Ward, Gregory, Hall, Jonathan and Prins, John (2007). Evidence of altered cortisol metabolism in critically ill patients: a prospective study. Intensive Care Medicine, 33 (10), 1746-1753. doi: 10.1007/s00134-007-0727-7
Relative adrenal insufficiency in sepsis:match point or deuce?
Venkatesh, B., Prins, J., Torpy, D., Chapman, M., Joyce, C., Cooper, D. J., Cohen, J., Hickman, I., Jones, D. and Higgins, A. (2006). Relative adrenal insufficiency in sepsis:match point or deuce?. Critical Care and Resuscitation, 8 (4), 376-380.
Still looking for the cause of fever?
Cohen, J. (2006). Still looking for the cause of fever?. Critical Care & Resuscitation, 8 (2), 155-156.
Cohen, Jeremy, Ward, Gregory, Prins, Johannes, Jones, Mark and Venkatesh, Bala (2006). Variability of cortisol assays can confound the diagnosis of adrenal insufficiency in the critically ill population. Intensive Care Medicine, 32 (11), 1901-1905. doi: 10.1007/s00134-006-0389-x
Assessment of adrenocortical function in the critically ill
Cohen, Jeremy and Venkatesh, Balasubramanian (2005). Assessment of adrenocortical function in the critically ill. Clinical Intensive Care, 16 (2), 89-95. doi: 10.1080/09563070500078319
Cohen, J., Venkatesh, B., Galligan, J. and Thomas, P. (2004). Salivary cortisol concentration in the intensive care population: correlation with plasma cortisol values. Anaesthesia and Intensive Care, 32 (6), 843-845.
Finfer, S. R. and Cohen, J. (2001). Severe traumatic brain injury. Resuscitation, 48 (1), 77-90. doi: 10.1016/S0300-9572(00)00321-X
Lee, Julie, Eley, Victoria, Wyssusek, Kerstin, Cohen, Jeremy, Rowell, John, Way, Mandy and van Zundert, Andre (2018). Rotational thromboelastometry (ROTEM®) in obstetrics: baseline parameters in uncomplicated and complicated pregnancies. a prospective observational study on elective Caesarean section patients. ANZCA Annual Scientific Meeting, Sydney, NSW, Australia, 7-11 May 2018. North Sydney, NSW, Australia: Sage Publications.
Lee, Julie, Eley, Victoria, Wyssusek, Kerstin, Cohen, Jeremy, Rowell, John, Kimble, Rebecca, Way, Mandy and van Zundert, Andre (2018). Rotational thromboelastometry (ROTEM®) in obstetrics: baseline parameters in uncomplicated and complicated pregnancies. a prospective observational study on parturients. ANZCA Annual Scientific Meeting, Sydney, NSW, Australia, 7-11 May 2018. North Sydney, NSW, Australia: Sage Publications.
Robinson, Katherine, Krishnan, Anand, Venkatesh, Karthik, Jones, Mark, Tocquer, Emeline, Bruneau, Diane, Grice, Jeff, Cohen, Jeremy, Prins, John and Venkatesh, Bala (2017). The temporal profile of adiponectin in healthy human subjects: a comparison with additional inflammatory and endocrine markers. Endocrine Society of Australia Annual Scientific Meeting 2016, Gold Coast, QLD, Australia, 21-24 August 2016. Hoboken, NJ, United States: Wiley-Blackwell.
Interstitium: The next diagnostic and therapeutic platform in critical illness
Venkatesh, Bala, Morgan, Thomas J. and Cohen, Jeremy (2010). Interstitium: The next diagnostic and therapeutic platform in critical illness. ISICEM 2010: 30th International Symposium on Intensive Care and Emergency Medicine, Bruxelles, Belgium, 9-12 March 2010. Baltimore, MD, U.S.A.: Lippincott Williams & Wilkins. doi: 10.1097/CCM.0b013e3181f24406
Tan, Tch, Chang, LPW, Mullins, B, Cohen, J, Venkatesh, B and Macdonald, GA (2009). The prevalence of adrenal insufficiency in patients with advanced liver disease using plasma free cortisol. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney , Australia, 21-24 October 2009. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.
Measurement of Adrenal Function in Critical Illness: The Role of Tissue Glucocorticoid Activity
Jeremy Cohen (2011). Measurement of Adrenal Function in Critical Illness: The Role of Tissue Glucocorticoid Activity. PhD Thesis, School of Medicine, The University of Queensland.
Vascular responsiveness in septic shock (NHMRC Project Grant led by UNSW)
(2019–2022) University of New South Wales
(2018–2023) Intensive Care Foundation
Enhancing host defence mechanisms in severe bacterial infections
(2018–2020) NHMRC Project Grant
(2017) University of New South Wales
(2016–2017) Royal Brisbane and Women's Hospital
Towards biomarkers for patient stratification in sepsis
(2016–2017) TRI Spore Grants
Gene expression profiling in critically ill patients with septic shock: The ADRENAL-GEPS Study
(2015–2018) NHMRC Project Grant
A biomarker for sepsis to thwart antibiotic overuse in the intensive care unit
(2015–2016) Royal Brisbane and Women's Hospital
Are burns survivors at increased risk of cardiovascular disease?
(2013–2015) Royal Brisbane and Women's Hospital
IMPACT: Improving Psychological health And decreasing Cardiovascular risk in patienTs post burns
(2012–2013) Royal Brisbane and Women's Hospital
(2011–2015) University of Sydney
(2011–2014) Royal Brisbane & Women's Hospital Research Foundation
Tissue cortisol activity in critical illness
(2008–2011)
(2006–2010) Australian & New Zealand College of Anaesthetists
The Metabolic Syndrome in Critical Illness
(2006) Australian & New Zealand College of Anaesthetists
Critical care management of burns patients
Doctor Philosophy — Associate Advisor
Other advisors:
Bacteria-induced WNT responses and their role in infection-associated inflammation
(2023) Doctor Philosophy — Associate Advisor
Other advisors:
(2021) Doctor Philosophy — Associate Advisor
Study of the disposition of nebulized tobramycin
(2019) Doctor Philosophy — Associate Advisor
Other advisors:
(2013) Doctor Philosophy — Associate Advisor