Dr Stefan Blum

Academic Title-Senior Lecturer

Princess Alexandra Hospital Southside Clinical Unit
Faculty of Medicine

Overview

Stefan is a Staff Specialist in Neurology at the Princess Alexandra Hospital (PAH) and the Mater Centre for Neuroscience, as well as an honourary staff specialist in Neurology at the Royal Brisbane Hospital (RBWH). He finished his training as neurologist in 2012.

He runs dedicated multiple sclerosis (MS) clinics at the PAH and Mater Hospital, leading in modern MS therapies. Moreover, he has been at the forefront of advancing the field of neuroimmunology in Queensland, with establishment of dedicated neuroimmunology outpatient clinics at the RBWH and PAH, combining expertise from neurologists and immunologists in the care of this very complex group of disorders.

In addition to his busy, full-time clinical workload, Stefan has been involved as PI or CI in a range of clinical trials in the fields of MS, botulinum toxin, CIDP and Pompe’s disease. Additionally, he has performed and is involved in ongoing research projects of neuroimmunological disorders such as neuromyelitis optica, myasthenia gravis and autoimmune limbic encephalitis. He has been a member of the New Horizons study to assess prevalence of anti-neuronal antibodies in patients with new onset psychosis.

Prior to this, Stefan finished a PhD in the field of ‘Immunogenetics of Guillain-Barre Syndrome and Chronic inflammatory polyneuropathy’ at the University of Queensland in 2014. He also completed a doctoral thesis at the University of Heidelberg, Germany in 2002 in the field of T cell immunology. During this time, he has developed solid skills in bench-side immunological research.

Currently, he is neurological lead in a diverse group of clinicians and scientists investigating the role of antineuronal antibodies in neurological and psychiatric disease. He supervises a PhD student in the field of advanced imaging in autoimmune encephalitis. He is currently building up a laboratory to test antineuronal antibodies using live cell assays.

Research Interests

  • Neuronal cell surface antibodies in neurological and psychiatric disease
  • Social cognition in Multiple Sclerosis
  • The role of low dose Rituximab in autoimmune neurological disease

Research Impacts

Stefan has been medical advisor and organiser of conferences of the national myasthenia gravis association. He is neurological advisor of the state-wide blood product services regarding use of immunoglobulins in neuroimmunological disorders. He is involved in the organisation of the International Society of Neuroimmunology Conference in Brisbane 2018. He is secretary of Neuroimmunology Australia, a national group of clinicians and researchers in the field of neuroimmunology. He was lead clinician in the development of referral guidelines for state-wide referral guidelines to Queensland Health Neurology services (CPC). He has been involved for many years in the education of medical student and young doctors, winning several teaching awards.

Publications

  • Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian-Guo, Varghese, Leila ... Silke, John (2020). A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature Communications, 11 (1) 3150, 3150. doi: 10.1038/s41467-020-16819-z

  • Khalilidehkordi, Elham, Clarke, Laura, Arnett, Simon, Bukhari, Wajih, Jimenez Sanchez, Sofia, O'Gorman, Cullen, Sun, Jing, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brown, Matthew, Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon ... Broadley, Simon A. (2020). Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation. Frontiers in Neurology, 11 537, 537. doi: 10.3389/fneur.2020.00537

  • Warren, Nicola, Flavell, Joshua, O'Gorman, Cullen, Swayne, Andrew, Blum, Stefan, Kisely, Steve and Siskind, Dan (2020). Screening for anti-NMDAR encephalitis in psychiatry. Journal of Psychiatric Research, 125, 28-32. doi: 10.1016/j.jpsychires.2020.03.007

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Supervision

  • Doctor Philosophy

  • Doctor Philosophy

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Publications

Journal Article

Conference Publication

Other Outputs

PhD and MPhil Supervision

Current Supervision