Professor Pamela McCombe

Professor

UQ Centre for Clinical Research
Faculty of Medicine
pamela.mccombe@uq.edu.au
+61 7 334 66017

Overview

Neurologist

Dr McCombe graduated in Medicine from UQ and completed a Science degree for medical students. She then trained as a neurologist in Sydney, at Prince Henry and Prince of Wales Hospitals. She obtained a PhD from the University of Sydney. She obtained experience in Neurophysiology in Cleveland and then returned to UQ as a post-doctoral fellow. She worked for some years as a research fellow in Neuroimmunology and was an NHMRc SRF. Later she resumed clinical practice as a neurologist, and contimued her research as an NHMRC Practitioner Fellow. She is currentlyProfessor and Head of the Royal Brisbane Clinical school in the School of Medicine and Co-head of the Brain and Mental Health Theme at the UQ Centre for Clinical Research.

Research Interests

  • Biomarkers and heterogeneity in ALS
    One of the challenges of ALS is understanding disease heterogeneity. Our work studies the variability of patients by detailed clinical, laboratory and genetic studies, and by identifying biomarkers that are associated with disease. We use a range of techniques including neurophysiology, MRI, metabolic studies, genetic studies, immune markers and biochemical studies including proteomics. We are using this information to analyse whether patients can be assigned into subgroups and to correlated with survival.
  • Inflammatory neuropathy studies
    This is an ongoing study of the immunological basis and genetic basis of acute and chronic inflammatory neuropathy
  • Pregnancy and MS
    This study is exploring the short and long term effects of pregnancy in multiple sclerosis. This includes the clinical effects of pregnancy and the effects on gene expression and methylation
  • Immunology of stroke
    This study involves documenting the immune responses after human stroke and determining the significance of these responses.
  • Neuromuscular disease
    This work is based at the Neuromuscular clinic at Royal Brisbane and Women's Hospital, and involves correlation of genotype and phenotype of inherited neuromuscular disease

Qualifications

  • FRACP
  • PhD, The University of Sydney
  • BSc, The University of Queensland
  • MBBS, The University of Queensland

Publications

  • Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian-Guo, Varghese, Leila ... Silke, John (2020). A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature Communications, 11 (1) 3150, 3150. doi: 10.1038/s41467-020-16819-z

  • Oh, Jiwon, Achiron, Anat, Celius, Elisabeth G., Chambers, Christina, Derwenskus, Joy, Devonshire, Virginia, Hellwig, Kerstin, Hutton, George J., McCombe, Pamela, Moore, Marie, Rog, David, Schneider, Jean-Raphael, Simm, Renata Faria, Sousa, Livia, Vincent, Stephen G., Chung, Luke, Daizadeh, Nadia, Mitchell, Colin and Compston, D. Alastair S. (2020). Pregnancy outcomes and postpartum relapse rates in women with RRMS treated with alemtuzumab in the phase 2 and 3 clinical development program over 16 years. Multiple Sclerosis and Related Disorders, 43 102146, 102146. doi: 10.1016/j.msard.2020.102146

  • Kunchok, Amy, Lechner-Scott, Jeannette, Granella, Franco, Trojano, Maria, Alroughani, Raed, Sola, Patrizia, Ferraro, Diana, Lugaresi, Alessandra, Onofrj, Marco, Ozakbas, Serkan, Izquierdo, Guillermo, Grammond, Pierre, Luis Sanchez-Menoyo, Jose, Van Wijmeersch, Bart, Boz, Cavit, Pucci, Eugenio, McCombe, Pamela, Grand'Maison, Francois, Spitaleri, Daniele, Vucic, Steve, Hupperts, Raymond, Jokubaitis, Vilija, Sormani, Maria Pia, Butzkueven, Helmut and Kalincik, Tomas (2020). Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score. Multiple Sclerosis Journal, 1352458520936823. doi: 10.1177/1352458520936823

View all Publications

Publications

Book

  • Pender, Michael P. and McCombe, Pamela A. (2009). Autoimmune neurological disease. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/cbo9780511526916

Book Chapter

  • McCombe, Pamela A. and Greer, Judith M. (2019). Sexual dimorphism in the immune system. The autoimmune diseases. (pp. 419-428) edited by Noel R. Rose and Ian R. Mackay. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-812102-3.00024-5

  • Ngo, Shyuan T., Steyn, Frederik J., McCombe, Pamela A. and Borges, Karin (2015). High Caloric diets for amyotrophic lateral sclerosis. Bioactive nutraceuticals and dietary supplements in neurological and brain disease: prevention and therapy. (pp. 355-361) edited by Ronald Ross Watson and Victor R. Preedy. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-411462-3.00036-9

  • McCombe, Pamela A. and Greer, Judith M. (2014). Sexual dimorphism in the immune system. The Autoimmune Diseases. (pp. 319-328) edited by Ian R. Mackay and Noel R. Rose. San Diego, United States: Academic Press. doi: 10.1016/B978-0-12-384929-8.00024-1

Journal Article

Conference Publication

  • Pelletier, D., Arnold, D. L., Bass, A. D., Boyko, A. N., Broadley, S., Comi, G., McCombe, P., Montalban, X., Pozzilli, C., Rovira, A., Selmaj, K. W., Singer, B. A., Vermersch, P., Chung, L., Poole, E. and Wray, S. (2020). Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-up. Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, West Palm Beach, FL, United States, 27-29 February 2020. London, United Kingdom: Sage Publications.

  • Sharmin, S., Lefort, M., Andersen, J., Horakova, D., Havrdova, E. K., Alroughani, R., Izquierdo, G., Eichau, S., Ozakbas, S., Butzkueven, H., Patti, F., Onofrj, M., Lugaresi, A., Terzi, M., Grammond, P., Grand'Maison, F., Yamout, B., Prat, A., Girard, M., Duquette, P., Boz, C., Trojano, M., McCombe, P., Slee, M., Lechner-Scott, J., Turkoglu, R., Sola, P., Ferraro, D., Granella, F. ... Kalincik, T. (2019). Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis. 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, Sep 11-13, 2019. LONDON: SAGE PUBLICATIONS LTD.

  • Comi, G., Arnold, D. L., Boyko, A. N., Hartung, H. -P., Havrdova, E. K., Inshasi, J. S., McCombe, P., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S. and Van Wijmeersch, B. (2019). Alemtuzumab improves clinical and MRI outcomes, including slowing of brain volume loss, in RRMS patients over 8 years: CARE-MS I follow-up (TOPAZ Study). 5th Congress of the European-Academy-of-Neurology (EAN), Oslo Norway, Jun 29-Jul 02, 2019. HOBOKEN: WILEY.

  • Sprenger, T., Lebrun-Frenay, C., Vermersch, P., Park, M. S., Chinchilla, D., McCombe, P., Lincoln, J., Bergsland, N., Dwyer, M., Kappos, L., Cavalier, S., Roesch, N., Guce, M., Poole, E. and Zivadinov, R. (2019). Investigating the effect of teriflunomide on diffuse cortical grey matter volume loss in the phase 3 TOPIC study. 5th Congress of the European-Academy-of-Neurology (EAN), Oslo Norway, Jun 29-Jul 02, 2019. HOBOKEN: WILEY.

  • Kunchok, Amy, Malpas, Charles, Nytrova, Petra, Havrdova, Eva, Alroughani, Raed, Terzi, Murat, Yamout, Bassem, Hor, Jyh Yung, Karabudak, Rana, Boz, Cavit, Ozakbas, Serkan, Olascoaga Urtaza, Francisco Javier, Simo, Magdolna, Granella, Franco, Patti, Francesco, McCombe, Pamela, Csepany, Tunde, Singhal, Bhim, Bergamaschi, Roberto, Fragoso, Yara, Al-Harbi, Talal, Turkoglu, Recai, Lechner-Scott, Jeannette, Laureys, Guy, Oreja-Guevara, Celia, Pucci, Eugenio, Sola, Patrizia, Ferraro, Diana, Altintas, Ayse ... Kalincik, Tomas (2019). Clinical determinants and therapeutic modifiers of relapse and disability outcomes in neuromyelitis optica spectrum disorder. 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia Pa, May 04-10, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

  • Pelletier, Daniel, Arnold, Douglas L., Boyko, Alexey N., Comi, Giancarlo, Hartung, Hans-Peter, Havrdova, Eva Kubala, Inshasi, Jihad Said, McCombe, Pamela, Nakamura, Kunio, Oreja-Guevara, Celia, Pozzilli, Carlo, Selmaj, Krzysztof W., Scott, Thomas F., Chung, Luke, Daizadeh, Nadia, Afsar, Salman and Van Wijmeersch, Bart (2019). Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study). 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia Pa, May 04-10, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

  • Sprenger, Till, Lebrun-Frenay, Christine, Vermersch, Patrick, Park, Min Su, Chinchilla, Dennis, McCombe, Pamela, Lincoln, John, Kappos, Ludwig, Bergsland, Niels, Dwyer, Michael, Cavalier, Steven, Roesch, Nora, Somera-Molina, Kathleen, Poole, Elizabeth and Zivadinov, Robert (2019). Investigating the Effect of Teriflunomide on Brain Volume Loss in the Phase 3 TOPIC Study. 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia Pa, May 04-10, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

  • McCombe, P., Comi, G., Arnold, D. L., Boyko, A. N., Hartung, H-P., Havrdova, E. K., Inshasi, J. S., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S. and Van Wijmeersch, B. (2019). Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study). Congress of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Sydney, NSW Australia, 2018. London, United Kingdom: Sage.

  • Montalban, X., Arnold, D. L., Boyko, A. N., Comi, G., Hartung, H.-P., Havrdova, E. K., Inshasi, J. S., McCombe, P., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Scott, T. F., Vieira Alves Leon, S., Chung, L., Daizadeh, N., Afsar, S. and Selmaj, K. W. (2019). Alemtuzumab maintains efficacy on clinical and MRI disease activity outcomes, including slowing of brain volume loss, over 9 years in RRMS patients: CARE-MS I follow-up (TOPAZ study). 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

  • Lechner-Scott, Jeannette, Maltby, Vicky, Lyndon, Amanda, Monif, Mastura, Kilpatrick, Trevor, Butzkueven, Helmut, Taylor, Bruce, McCombe, Pamela, Hodgkinson, Suzanne, Fabis-Pedrini, Marzena, Kermode, Allan, Barnett, Michael and Kalincik, Tomas (2019). Cladribine: a multicentre long-term efficacy biomarker australian study (CLOBAS). Annual Scientific Meeting of the Australian and New Zealand Association of Neurologists (ANZAN), Sydney, Australia, May 21-24, 2019. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2019-anzan.119

  • Celius, E. G., Achiron, A., Compston, D. A. S., Derwenskus, J., Devonshire, V., Hellwig, K., Hutton, G. J., McCombe, P., Moore, M., Oh, J., Simm, R. F., Sousa, L., Vincent, S. G., Chung, L., Daizadeh, N., Mitchell, C. and Rog, D. (2019). Postpartum relapse after first on-study pregnancy in RRMS patients treated with alemtuzumab in the phase 2 and 3 clinical development program over 8 years. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

  • McCombe, P., Vukusic, S., Coyle, P. K., Jurgensen, S., Truffinet, P., Benamor, M., Poole, E., Chavin, J. and Chambers, C. (2019). Pregnancy Outcomes in Patients with MS Treated with Teriflunomide: Clinical Study and Postmarketing Data. Congress of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Sydney, NSW Australia, 2018. London, United Kingdom: Sage.

  • Comi, G., Arnold, D. L., Boyko, A. N., Hartung, H. -P., Havrdova, E. K., Inshasi, J. S., McCombe, P., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S., Nakamura, K. and Van Wijmeersch, B. (2018). Alemtuzumab improves clinical and MRI disease activity outcomes, including slowing of brain volume loss, in RRMS patients over 8 years: CARE-MS I follow-up (TOPAZ study). 34th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Berlin Germany, Oct 10-12, 2018. LONDON: SAGE PUBLICATIONS LTD.

  • Spelman, T., Harvrdova, E. K., Horakova, D., Izquierdo, G., Kalincik, T., Lugaresi, A., Onofrj, M., Duquette, P., Girard, M., Prat, A., Grammond, P., Grand'Maison, F., Granella, F., Lechner-Scott, J., Sola, P., Ferrero, D., Sa, M. J., Terzi, M., Ozakbas, S., Van Pesch, V., Van Wijmeersch, B., Boz, C., Karabudak, R., Cartechini, E., McCombe, P. and Butzkueven, H. (2018). Comparative effectiveness of switching to natalizumab or fingolimod after relapse on first-line relapsing-remitting multiple sclerosis therapy: propensity score matching analysis from the MSBase registry. 34th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Berlin Germany, Oct 10-12, 2018. LONDON: SAGE PUBLICATIONS LTD.

  • Husin, H., Wallace, J., Malpas, C., Sharmin, S., Horakova, D., Havrdova, E. Kubala, Izquierdo, G., Eichau, S., Prat, A., Girard, M., Duquette, P., Trojano, M., Grammond, P., Lugaresi, A., Onofrj, M., Ozakbas, S., Butzkueven, H., Sola, P., Ferraro, D., Alroughani, R., Grand'Maison, F., Terzi, M., Lechner-Scott, J., Boz, C., Hupperts, R., Shaygannejad, V., Bergamaschi, R., Pucci, E., Van Pesch, V. ... Kalincik, T. (2018). Determinants of MS re-activation after discontinuing therapies. 34th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Berlin Germany, Oct 10-12, 2018. LONDON: SAGE PUBLICATIONS LTD.

  • Kister, Ilya, Bacon, Tamar, Shaygannejad, Vahid, Havrdova, Eva, Alroughani, Raed, Terzi, Murat, Altintas, Ayse, Hor, Jyh Yung, Al-Harbi, Talal, Boz, Cavit, Bergamaschi, Roberto, Ozakbas, Serkan, Ferraro, Diana, Fragoso, Yara, Laureys, Guy, Soysal, Aysun, Majdinassab, Nastaran, Onofrj, Marco, Pucci, Eugenio, Vucic, Ostoja (Steve), Slee, Mark, Lechner-Scott, Jeannette, Rojas, Juan Ignacio, Burgos, Marcos, Castillo Trivino, Tamara, Reid, Allyson, Rimler, Zoe, McCombe, Pamela, Granella, Franco ... Butzkueven, Helmut (2018). Presentation of Neuromyelitis Optica (NMO) in patients from different racial groups: analysis of the global NMOBase Registry. 70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los Angeles Ca, Apr 21-27, 2018. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

  • Van Wijmeersch, B., Vermersch, P., Boyko, A., de Seze, J., Hartung, H. -P., Havrdova, E. Kubala, Inshasi, J. Said, McCombe, P., Montalban, X., Pozzili, C., Melanson, M., Daizadeh, N., Rodriguez, C. and Selmaj, K. (2018). Alemtuzumab provides durable clinical efficacy in patients with active rrms in the absence of continuous treatment: 7-Year follow-up of CARE-MS I (TOPAZ Study). 4th Congress of the European Academy of Neurology (EAN), Lisbon, Portugal, 16-19 June 2018. Chichester, West Sussex, United Kingdom: Wiley-Blackwell.

  • Vermersch, Patrick, Coles, Alasdair J., Boyko, Alexey N., De Seze, Jerome, Hartung, Hans-Peter, Havrdova, Eva, Inshasi, Jihad Said, McCombe, Pamela, Montalban, Xavier, Pozzilli, Carlo, Selmaj, Krzysztof W., Margolin, David H., Melanson, Maria, Daizadeh, Nadia, Rodriguez, Claudio E. and Van Wijmeersch, Bart (2018). Durable Clinical Efficacy of Alemtuzumab in Patients With Active RRMS in the Absence of Continuous Treatment: 7-Year Follow-up of CARE-MS I Patients (TOPAZ Study). 70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los Angeles, CA, United States, Apr 21-27, 2018. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

  • Steingo, Brian, Oreja-Guevara, Celia, Alroughani, Raed, Brassat, David, Boyko, Alexey N., McCombe, Pamela, Van Wijmeersch, Bart, Margolin, David H., Melanson, Maria, Daizadeh, Nadia, Rodriguez, Claudio E. and Vermersch, Patrick (2018). Durable Efficacy and Safety With Alemtuzumab in CARE-MS I Patients Switching From SC IFNB-1a: 5-Year Follow-up (TOPAZ Study). 70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los Angeles, CA, United States, Apr 21-27, 2018. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

  • McCombe, Pamela, Boyko, Alexey N., DeSeze, Jerome, Hartung, Hans-Peter, Havrdova, Eva, Inshasi, Jihad Said, Montalban, Xavier, Pozzilli, Carlo, Selmaj, Krzysztof W., Vermersch, Patrick, Melanson, Maria, Daizadeh, Nadia, Rodriguez, Claudio E. and Van Wijmeersch, Bart (2018). Durable clinical efficacy of alemtuzumab in patients with active rrms in the absence of continuous treatment: 7-year follow-up of CARE-MS I patients (Topaz Study). Annual Scientific Meeting of the Australian-and-New Zealand-Association-of-Neurologists (ANZAN), Darwin Australia, May 29 - June 1 2018. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2018-ANZAN.43

  • Inshasi, Jihad Said, Boyko, Alexey N., De Seze, Jerome, Hartung, Hans-Peter, Havrdova, Eva, McCombe, Pamela, Montalban, Xavier, Pozzilli, Carlo, Vermersch, Patrick and Margolin, David H. (2018). Durable improvements in clinical outcomes with alemtuzumab in patients with active relapsing-remitting multiple sclerosis in the absence of continuous treatment: 7-year follow-up of CARE-MS I patients (TOPAZ study). 3rd Congress of Middle East North Africa Committee for Research and Treatment in Multiple Sclerosis (MENACTRIMS), Dubai, UAE, 24-25 November 2017 . London, United Kingdom : Sage Publications.

  • Oreja-Guevara, C., Alroughani, R., Brassat, D., Boyko, A. N., McCombe, P., Steingo, B., Van Wijmeersch, B., Margolin, D. H., Daizadeh, N., Rodriguez, C. E. and Vermersch, P. (2017). Alemtuzumab demonstrated durable efficacy and safety in CARE-MS I patients switching from SC IFNB-1a: 5-year follow-up after alemtuzumab (TOPAZ study). 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

  • Coles, A. J., Boyko, A. N., De Seze, J., Hartung, H-P., Havrdova, E., Inshasi, J. S., McCombe, P., Montalban, X., Pozzilli, C., Selmaj, K. W., Vermersch, P., Margolin, D. H., Daizadeh, N., Rodriguez, C. E. and Van Wijmeersch, B. (2017). Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study). 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

  • Kalincik, T., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Lechner-Scott, J., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Solaro, C., Grand'Maison, F., Hupperts, R., Prevost, J., Sola, P., Ferraro, D., Terzi, M., Butler, E., Slee, M., Kermode, A., Fabis-Pedrini, M., McCombe, P., Barnett, M., Shaw, C., Hodgkinson, S. and Butzkueven, H. (2017). Cladribine versus fingolimod, natalizumab and interferon beta for multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

  • Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

  • Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of faecal microbe diversity between motor neurone disease (MND) and control participants. Annual Scientific Meeting of the Australian and New Zealand Association of Neurologists (ANZAN), Gold Coast Australia, May 9-12, 2017. London, United Kingdom: BMJ Publishing. doi: 10.1136/jnnp-2017-316074.81

  • Kalincik, T., Spelman, T., Jokubaitis, V., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Grammond, P., Alroughani, R., Lechner-Scott, J., Prevost, J., Terzi, M., Grand'Maison, F., Boz, C., Trojano, M., Van Wijmeersch, B., Pucci, E., Granella, F., Turkoglu, R., Sola, P., Ferraro, D., McCombe, P., Solaro, C., Van Pesch, V., Ozakbas, S., Slee, M. ... Butzkueven, H. (2017). Effectiveness of fingolimod, dimethyl fumarate and teriflunomide in relapsing-remitting multiple sclerosis: a comparative longitudinal study. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

  • Xu, Zhouwei, Lee, Aven, Henderson, Robert and McCombe, Pamela (2017). Gelsolin, clusterin and Cd5L are the potential plasma biomarkers of amyotrophic lateral sclerosis with and without cognitive impairment. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.34

  • Ioannides, Zara A., Ngo, Shyuan T., Henderson, Robert D., McCombe, Pamela A. and Steyn, Frederik J. (2017). Hypermetabolism in Motor Neurone Disease Is Associated with a Greater Functional Decline But Not Weight Loss. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.18

  • Spelman, T., Schulz, M., Arora, B., Chung, E., Juneja, P., Walker, R., Verhaeghe, S., Butzkueven, H., Hodgkinson, S., Lechner-Scott, J., McCombe, P., Slee, M., Butler, E., Barnett, M., Skibina, O., Vucic, S., Macdonell, R., Shuey, N., Taylor, B. and Broadley, S. (2017). Persistence to fingolimod compared with other disease modifying therapies in the Australian real-world setting using the MS base registry. 7th Joint European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)-Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications.

  • Jokubaitis, V. G., Havrdova, E., Horakova, D., Izquierdo, G., Kalincik, T., van der Walt, A., Nguyen, A. -L., Terzi, M., Alroughani, R., Duquette, P., Girard, M., Prat, A., Boz, C., Sola, P., Lugaresi, A., Lechner-Scott, J., Barnett, M., Grand'Maison, F., Grammond, P., Ramo, C., Turkoglu, R., McCombe, P., Hupperts, R., Bolanos, R. Fernandez, Pucci, E., Trojano, M., Granella, F., Spitaleri, D., Van Pesch, V. ... Butzkueven, H. (2017). Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

  • Jokubaitis, Vilija, Ai-Lan Nguyen,, Kalincik, Tomas, van der Walt, Anneke, Lechner-Scott, Jeannette, Barnett, Michael, McCombe, Pamela, Vucic, Steve, Hodgkinson, Suzanne, Slee, Mark, Skibina, Olga, Shaw, Cameron and Butzkueven, Helmut (2017). Pregnancy incidence, therapy exposure and post-partum relapse risk: a 12-year retrospective multicentre analysis. Progress in MS Research Conference, Sydney, Australia, 11-13 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517734699

  • Rog, D., Oh, J., Chambers, C., Hellwig, K., McCombe, P., Otero, S., Margolin, D. H., Daizadeh, N. and Compston, D. A. S. (2017). Pregnancy outcomes in patients with RRMS treated with alemtuzumab from the clinical development program. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

  • Fambiatos, A., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Izquierdo, G., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Alroughani, R., Terzi, M., Hupperts, R., Boz, C., Lechner-Scott, J., Pucci, E., Bergamaschi, R., Van Pesch, V., Ozakbas, S., Granella, F., Ramo, C., Turkoglu, R., Iuliano, G., Spitaleri, D. ... Kalincik, T. (2017). Risk of secondary progressive multiple sclerosis: a longitudinal study. 7th Joint European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)-Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications.

  • Xu, Zhouwei, Alruwaili, Ashwag, Henderson, Robert and McCombe, Pamela (2017). Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: Frequency of abnormality and effect on survival. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.29

  • Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Prat, A., Girard, M., Hupperts, R., Van Pesch, V., Ferraro, D., Alroughani, R., Bergamaschi, R., Pucci, E., Iuliano, G., Lechner-Scott, J., Spelman, T., Jokubaitis, V., Ramo-Tello, C., Spitaleri, D., Granella, F., Solaro, C., Ampapa, R., Deri, N., McCombe, P., Petersen, T., Van Wijmeersch, B., Prevost, J., Sanchez-Menoyo, J. L. ... Robsertson, N. (2017). The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731283

  • Ioannides, Zara A., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2017). The risk of overestimating fatness in motor neurone disease: longitudinal assessments of body composition. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.35

  • Brown, J. W. L., Lugaresi, A., Horakova, D., Havrdova, E., Jokubaitis, V., Lechner-Scott, J., Trojano, M., Min, M., Shaw, C., Shuey, N., Slee, M., Mccombe, P., Van Pesch, V., Van Wijmeersch, B., Prevost, J., Moore, F., Prat, A., Girard, M., Duquette, P., Ayrignac, X., Sempere, A. Perez, Sanchez-Menoyo, J. L., Ramo-Tello, C., Csepany, T., Hutchinson, M., De Luca, G., Bergamaschi, R., Granella, F., Curti, E. ... Kalincik, T. (2017). The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517733228

  • Merkel, Bernd, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, McCombe, Pamela, Slee, Mark, Vucic, Steve, Skibina, Olga, Barnett, Michael, Hodgkinson, Suzanne, Butzkueven, Helmut and Kalincik, Tomas (2017). Timing of High-Efficacy Disease Modifying Therapies for Relapsing-Remitting Multiple Sclerosis. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.16

  • Merkel, B., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Sola, P., Ferraro, D., Grammond, P., Hupperts, R., Bergamaschi, R., Alroughani, R., Boz, C., Terzi, M., Pucci, E., Van Pesch, V., Grand'Maison, F., Fernandez-Bolanos, R., Lechner-Scott, J., Spitaleri, D., Shaygannejad, V., Iuliano, G., Granella, F., Solaro, C. ... Kalincik, T. (2017). Timing of high-efficacy disease modifying therapies for relapsing-remitting multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731283

  • McCombe, P. A., Hartung, H-P, Havrdova, E., Selmaj, K. W., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • McCombe, P., Achiron, A., Chambers, C., Fox, E. J., Otero, S., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • Coles, A. J., Boyko, A. N., Cohen, J. A., De Seze, J., Fox, E. J., Havrdova, E., Hartung, H. -P., Inshasi, J. S., McCombe, P., Selmaj, K. W., Vermersch, P., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Montalban, X. (2016). Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Kalincik, T., Lizak, N., Jokubaitis, V., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M., Parratt, J., Butzkueven, H. and Hodgkinson, S. (2016). Australian cladribine experience. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Kalincik, T., Brown, J. W., Robertson, N., Willis, M., Scolding, N., Pearson, O., Ziemssen, T., Hutchinson, M., McGuigan, C., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Alroughani, R., Pucci, E., Sola, P., Hupperts, R., Lechner-Scott, J., Fernandez Bolanos, R., Terzi, M., Van Pesch, V., Rozsa, C. ... Coles, A. (2016). Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Oreja-Guevara, C., Alroughani, R., Brassat, D., Boyko, A. N., McCombe, P., Steingo, B., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Vermersch, P. (2016). Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up). 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Kalincik, T., Sobisek, L., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Girard, M., Prat, A., Duquette, P., Grammond, P., Sola, P., Hupperts, R., Grand'Maison, F., Pucci, E., Boz, C., Alroughani, R., Van Pesch, V., Lechner-Scott, J., Terzi, M., Bergamaschi, R., Iuliano, G., Granella, F., Spitaleri, D., Shaygannejad, V., Oreja-Guevara, C., Slee, M. ... Butzkueven, H. (2016). Individual response to disease modifying therapies: a global observational cohort study. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Rog, David, Chambers, Christina, McCombe, Pamela, Otero, Susana, Hellwig, Kerstin, Margolin, David, Thangavelu, Karthinathan and Oh, Jiwon (2016). Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms. Annual Meeting of the Association-of-British-Neurologists (ABN), Brighton, England, May 17-19, 2016. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2016-315106.155

  • Jokubaitis, V. G., Kalincik, T., Lorscheider, J., Spelman, T., Horakova, D., Duquette, P., Girard, M., Prat, A., Izquierdo, G., Grammond, P., Pucci, E., Grand'Maison, F., Granella, F., Sola, P., Bergamaschi, R., Iuliano, G., Spitaleri, D., Hodgkinson, S., Olascoaga, J., Verheul, F., McCombe, P., Rozsa, C., Lechner-Scott, J., Terzi, M., Hughes, S., Saladino, M. -L., Lugaresi, A., Trojano, M. and Butzkueven, H. (2016). Pregnancy protects against long-term disability accrual in relapsing-remitting MS. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

  • Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, McCombe, Pam, Vucic, Steve, Barnett, Michael, Butzkueven, Helmut and Kalincik, Tomas (2015). Defining secondary progressive multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne Australia, Oct 29-30, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • Jokubaitis, V. G., Spelman, T., Kalincik, T., Travaglini, D., Paolicelli, D., Duquette, P., Girard, M., Prat, A., Havrdova, E., Horakova, D., Izquierdo, G., Grammond, P., Pucci, E., Grand'Maison, F., Bergamaschi, R., Granella, F., Van Pesch, V., Hupperts, R., Iuliano, G., Spitaleri, D., Sola, P., Boz, C., Fernandez-Bolanos, R., Petersen, T., Verheul, F., Olascoaga, J., McCombe, P., Rozsa, C., Lechner-Scott, J. ... Trojano, M. (2015). 10-year progression predictors after first treatment initiation in a relapsing-remitting MS cohort. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • Lorscheider, J., Buzzard, K., Jokubaitis, V., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Girard, M., Duquette, P., Prat, A., Lugaresi, A., Grand'Maison, F., Grammond, P., Hupperts, R., Alroughani, R., Sola, P., Boz, C., Terzi, M., Pucci, E., Lechner-Scott, J., Bergamaschi, R., Oreja-Guevara, C., Iuliano, G., Van Pesch, V., Bolanos, R. Fernandez, Granella, F., Rio, M. E., Ramo, C. ... Kalincik, T. (2015). Defining secondary progressive multiple sclerosis. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • Stewart, T., Jokubaitis, V., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Girard, M., Duquette, P., Prat, A., Lugaresi, A., Grammond, P., Grand'Maison, F., Sola, P., Hupperts, R., Petersen, T., Pucci, E., Bergamaschi, R., Boz, C., Oreja-Guevara, C., Lechner-Scott, J., Alroughani, R., Ramo, C., Van Pesch, V., Fernandez-Bolanos, R., Iuliano, G., Rio, M. E., Granella, F., Slee, M. ... Kalincik, T. (2015). Effect of relapse phenotype on the accumulation of disability in relapsing-remitting multiple sclerosis. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

  • Achiron, A., Chambers, C., Fox, E. J., Mc Combe, P., Otero, S., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2015). Pregnancy outcomes in patients with active RRMS who received alemtuzumab in the clinical development program. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015.

  • Kalincik, Tomas, Stewart, Tamasine, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, Slee, Mark, Hodgkinson, Suzanne, McCombe, Pamela, Barnett, Michael, Vucic, Steve, Shuey, Neil, Shaw, Cameron and Butzkueven, Helmut (2015). Contribution of various relapse phenotypes to disability in multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne, Australia, Oct 29-30, 2015. London, United Kingdom: Sage Publications. doi: 10.1177/1352458515616527

  • Jokubaitis, Vilija, Spelman, Tim, Kalincik, Tomask, Lorscheider, Johannes, McCombe, Pamela, Lechner-Scott, Jeannette, Hodgkinson, Suzanne and Butzkueven, Helmut (2015). First-line injectable therapy and pregnancy protect against long-term disability accrual in patients with relapse-onset multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne, Australia, Oct 29-30, 2015. London, United Kingdom: Sage Publications. doi: 10.1177/1352458515616527

  • Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188

  • McCombe, P., Achiron, A., Brinar, V., Margolin, D. H., Palmer, J., Oyuela, P. and Compston, D. A. S. (2015). Pregnancy outcomes in the alemtuzumab MS clinical development program. Pactrims Invited Lecture, Unknown, Unknown. London, United Kingdom: Sage Publications. doi: 10.1177/1352458514563659

  • Pow, D., Lee, A., Klinkradt, S., Balcar, V. and McCombe, P. (2015). The missing brain glutamate transporters: what we missed and how this changes our understanding of the excitable brain. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia Conference, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185

  • Sheikh, Nabeel, McCombe, Pamela and Blum, Stefan (2014). Cardiac effects of high-dose fingolimod ingestion. ANZAN Annual Scientific Meeting 2014, Adelaide, South Australia, Australia, May 2014. Elsevier. doi: 10.1016/j.jocn.2014.06.094

  • Yan, Jun, Greer, Judith, Mccombe, Pamela, Pender, Michael and Consortium, Anzgene (2014). Characterization of genetic variants in the NFKBIA promoter region in multiple sclerosis. 12th International Congress of Neuroimmunology (ISNI), Mainz, Germany, Nov 09-13, 2014. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.jneuroim.2014.08.141

  • Blum, Stefan, Csurhes, Peter, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2014). Killer immunoglobulin-like receptors and their HLA ligands in Guillain-Barré syndrome. ANZAN Annual Scientific Meeting 2014, Adelaide, South Australia, Australia, May 2014. Elsevier. doi: 10.1016/j.jocn.2014.06.032

  • Inglis, H., Greer, J. and McCombe, P. (2012). Gene expression in the spinal cord in MBP-EAE in pregnant and post-partum rats: implications for the effects of MS in pregnancy. 28th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis, Lyon France, Oct 10-13, 2012. LONDON: SAGE PUBLICATIONS LTD.

  • Inglis, H., Narayanan, R., Wallace, R., Greer, J. and McCombe, P. (2012). Changes in the gene expression and splicing in the CNS during pregnancy and post-partum in the rat. Progress in MS Research Conference 2011, Melbourne, VIC, Australia, 26-28 October 2011. London, United Kingdom: Sage Publications.

  • McCombe, Pamela, Liu, Jia, Yan, Jun and Greer, Judith (2012). Increased expression of the hypoxia related genes in peripheral blood cells of subjects with acute ischaemic stroke. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

  • Yan, J., Pender, M.P., Liu, J., McCombe, P.A., Greer, J.M. and ANZgene Consortium (2012). Investigation of gene mutations in the NFKBIA promoter region in patients with multiple sclerosis. Progress in MS Research Conference 2011, Melbourne, VIC, Australia, 26-28 October 2011. London, United Kingdom: Sage Publications.

  • McCombe, Pamela A., Baumann, Fusun, Henderson, Robert and Anthony, Pettitt (2011). Bayesian Statistical Motor Unit Number Estimation in the Assessment of ALS. 63rd Annual Meeting of the American-Academy-of-Neurology, Honolulu, HI, U.S.A., APR 09-16, 2011. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins.

  • McCombe, P, Ngo, S, Bellingham, M, Pettitt, A and Henderson, R (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd AAN Annual Meeting, Honolulu Hi, Apr 09-16, 2011.

  • McCombe, Pamela, Ngo, Shuyan, Bellingham, Mark, Pettitt, Anthony and Henderson, Robert (2011). Comparison of Motor Units Number Estimation by Bayesian Statistical MUNE with Histological Counting of Motor Unit Numbers: Validation of the Method. 63rd Annual Meeting of the American-Academy-of-Neurology, Honolulu, HI, U.S.A., APR 09-16, 2011. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins.

  • Ngo, S. T., Bellingham, M. C., Pettitt, A. N., Ridall, P. G., Henderson, R. D. and McCombe, P. A. (2011). Comparison of motor unit number estimation by Bayesian statistical MUNE with histological counting of motor unit numbers. 22nd International ALS/MND Symposium, Sydney, Australia, 30 November - 2 December 2011.

  • Ngo, S. T., Baumann, F., Pettitt, A. N., Ridall, P. G., Henderson, R. D., McCombe, P. A. and Bellingham, M. C. (2011). Estimation of Motor Unit Loss in Amyotrophic Lateral Sclerosis (ALS). Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand, 31 January -3 February 2011.

  • Steyn, F.J., Ngo, S.T., Buckley, A.J., Leong, J.W., Veldhuis, J.D., McCombe, P.A., Chen, C. and Bellingham, M.C. (2011). Pulsatile Growth Hormone Secretion in the SOD1G93A Mouse Model of ALS. Endocrine Society of Australia Annual Scientific Meeting, Perth Convention and Exhibition Centre, Perth, Western Australia, 28-31 August.

  • Ngo, S. T., Steyn, F. J., Buckley, A. J., Leong, J. W., Veldhuis, J. D., Chen, C., McCombe, P. A. and Bellingham, M. C. (2011). Pulsatile growth hormone secretion in the SOD1G93A mouse model of ALS resembles growth hormone deficiency in ALS patients. 22nd International ALS/MND Symposium, Sydney, Australia, 30 November - 2 December 2011.

  • Ngo, S.T., Bellingham, M.C., Baumann, F., Pettitt, A.N., Ridall, P.G., Henderson, R.D. and McCombe, P.A. (2010). Bayesian Motor Unit Number Estimation in the SOD1G93A mouse. Forum of European Neuroscience, AMSTERDAM NETHERLANDS, 3/7/2010-7/7/2010.

  • Blum, Stefan, Wong, Richard, Gillis, David, Wilson, Bob, Prain, Kerryn and McCombe, Pamela (2010). Clinical characteristics of Aquaporin 4 auto-antibody positive patients – A case series. ANZAN Annual Scientific Meeting 2014, Adelaide, South Australia, Australia, May 2014. Elsevier. doi: 10.1016/j.jocn.2010.07.067

  • Kleinschmidt, Grant D., Henderson, Robert D. and McCombe, Pamela (2010). Clinical features of patients with demyelinating neuropathy associated with Anti-MAG antibody. ANZAN Annual Scientific Meeting 2010, -, 2010. Elsevier. doi: 10.1016/j.jocn.2010.07.081

  • Badve, Monica S., Yan, J., Hull, R., Henderson, Robert, O’Sullivan, John D., Read, Stephen J., Wong, Andrew A. and McCombe, Pamela (2010). Immune response in acute ischaemic stroke. ANZAN Annual Scientific Meeting 2010, -, 2010. Elsevier. doi: 10.1016/j.jocn.2010.07.064

  • Blum, Stefan, Robertson, Thomas, Klingberg, Sandra, Henderson, Robert and McCombe, Pamela (2010). Unusual clinical presentations associated with the A3243G mutation. ANZAN Annual Scientific Meeting 2010, -, 2010. Elsevier. doi: 10.1016/j.jocn.2010.07.066

  • Ridall, P. G., Pettitt, A. N., McCombe, P. A. and Henderson, R. D. (2009). Bayesian analysis of the stimulus-response curve. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00004-4

  • McCombe, P. A., Henderson, R. D., Ridall, P. G. and Pettitt, A. N. (2009). Biological basis for motor unit number estimation through Bayesian statistical analysis of the stimulus-response curve. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00003-2

  • Henderson, R. D., Ridall, P. G., Pettitt, A. N. and McCombe, P. A. (2009). Results of Bayesian statistical analysis in normal and ALS subjects. 2nd International Symposium on MUNE and QEMG, Utah, United States, 18-20 August 2006. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S1567-424X(08)00005-6

  • Yan, J., Greer, J. M., Cavanagh, H., Henderson, R., O'Sullivan, J., Read, S., Etherington, K. and McCombe, P. A. (2007). Increased population of activated T cells in patients after acute ischemic stroke. 37th Annual Scientific Meeting of the Australasian Society for Immunology, Sydney, Australia, 2-6 December 2007.

  • McCombe, P. A., Csurhes, P. A., Alizart, M. A. and Greer, J. M. (2005). HLA-DR2 is associated with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in females, but not males. 5th Annual Meeting of the Federation-of-Clinical-Immunology-Society, Boston, MA, U.S.A., 12-16 May 2005. Orlando, Florida: Academic Press.

  • McCombe, P. A., Sullivan, A. A. and Alizart, M. A. (2002). Antibodies to PMP-22 peptides in inflammatory neuropathy. 10th International Congress on Neuromuscular Diseases, Vancouver BC, Canada, 7-12 July 2002. AMSTERDAM: ELSEVIER SCIENCE BV.

  • Pender, M. P., Csurhes, P. A., Wolfe, N. P., Cameron, K. D., McCombe, P. A., Greer, J. M. and Good, M. F. (2002). Blood T-cell reactivity to gangliosides GM3 and GQ1b is increased in patients with primary progressive multiple sclerosis. 127th Annual Meeting of the American Neurological Association, New York City, NY, USA, October 12-16 2002. NEW YORK: WILEY-LISS.

  • McCombe, P. A., Morton, J. and Saines, N. (2002). Multifocal motor neuropathy: Improvement after autologous bone marrow transplantation. 10th International Congress on Neuromuscular Diseases, Vancouver Canada, 7-12 July 2002. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0022-510X(02)80013-2

  • McCombe, P. A., Sullivan, A. A., Alizart, M. A., Csurhes, P. A., Greer, J. M. and Pender, M. P. (2002). T cell responses to gangliosides in patients with inflammatory neuropathy. Xth International Congress on Neuromuscular Diseases, Vancouver, Canada, 07-12 Jul 2002. Amsterda, The Netherlands: Elseiver. doi: 10.1016/S0022-510X(02)80069-7

  • Pender, M. P., Csurhes, P. A., Greer, J. M., Mowat, P. D., Henderson, R. D., Cameron, K. D., McCombe, P. A. and Good, M. F. (1999). Fluctuations in the frequencies of circulating myelin-reactive T cells in healthy subjects and patients with multiple sclerosis. ECTRIMS/ACTRIMS'99, Basel, Switzerland, 15 - 18 Sept, 1999. Basingstoke, England: Stockton Press.

  • Sullivan, A., Csurhes, P. A., Alizart, M., Pender, M. P. and McCombe, P. A. (1999). The role of PMP-22 as an autoantigen in GBS and CIDP. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.

  • Cameron, K. D., Csurhes, P. A., Good, M. F., Greer, J. M., Henderson, R. D., McCombe, P. A., Mowat, P. D. and Pender, M. P. (1998). The frequency of circulating T cells reactive to PLP184-209 increases prior to MS relapse and development of new MR1 lesions. Fifth International Congress of the International Society of Neuroimmunology, Montreal, Canada, August 23-27, 1998. doi: 10.1016/S0165-5728(98)91636-8

  • McCombe, P. A., Nickson, I. and Pender, M. P. (1997). Cytokine mRNA expression in lymphocytes from the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis. -, -, -. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/j.1750-3639.1997.tb01051.x

  • McCombe, P. A., Harness, J., Cavanagh, A. C. and Morton, H. (1997). Early pregnancy factor and experimental autoimmune encephalomyelitis. American Neurological Association Annual Meeting, San Diego CA, United States, 28 September - 1 October 1997. Hoboken, NJ, United States: John Wiley & Sons.

  • Pender, M. P., White, C. A. and McCombe, P. A. (1996). Decreased expression of the apoptosis inhibitor Bcl-2 in T cells in the central nervous system in experimental autoimmune encephalomyelitis. American Neurological Association Annual Meeting, Miami FL, United States, 13-16 October 1996. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ana.410400326

  • Pender, M. P., Greer, J. M., Csurhes, P. A., Cameron, K. D., McCombe, P. A. and Good, M. F. (1996). T-cell reactivity to peptides of proteolipid protein and myelin basic protein in multiple sclerosis. 121st Annual Meeting of the American Neurological Association, Miami, FL, U.S.A., 13-16 October 1996. BOSTON: LITTLE BROWN CO. doi: 10.1002/ana.410400326

  • Cameron, K., Csurhes, P., Greer, J., McCombe, P. and Pender, M. (1995). Reactivity to myelin proteolipid protein in multiple sclerosis patients. The 9th International Congress of Immunology, San Francisco, California, USA, 23-29 July 1995. San Francisco, California, USA: American Association of Immunologists and the International Union of Immunological Societies.

  • McCombe, P. A., Dejersey, J. and Pender, M. P. (1993). Chronic relapsing experimental autoimmune encephalomyelitis: Studies of cells from the spinal cord. Joint Meeting of the Australasian Society for Immunology and Society for Leukocyte Biology, Sydney, NSW, Australia, 1-5 December 1993. Bethesda, MD, United States: Federation of American Societies for Experimental Biology.

  • Tabi, Z., McCombe, P. A. and Pender, M. P. (1993). Flow cytometric analysis of apoptotic T cells isolated from the central nervous system in experimental autoimmune encephalomyelitis. Joint Meeting of the Australasian Society for Immunology and Society for Leukocyte Biology, Sydney, NSW, Australia, 1-5 December 1993. Bethesda, MD, United States: Federation of American Societies for Experimental Biology.

  • McCombe, P. A., Csurhes, P. A., Houghten, R. A., Good, M. F. and Pender, M. P. (1993). Human T cell responses to myelin basic protein isoforms. International Congress on the Regulation of Leukocyte Production and Immune Function held at the Joint Meeting of the Australasian Society for Immunology and Society for Leukocyte Biology, Sydney, New South Wales, Australia, 1-5 December 1993. Bethesda, MD, United States: Federation of American Societies for Experimental Biology.

  • McCombe, P. A., Pollard, J. D. and McLeod, J. G. (1988). Absence of antimyelin antibodies and serum demyelinating factors in most CIDP patients. -, -, -. Richmond, VIC, Australia: Wiley-Blackwell.

  • Feeney, D. J., Pollard, J. D., Stewart, G. J., Clark, P., McCombe, P., Kirk, R. L. and McLeod, J. G. (1985). Immunogenetics of human demyelinating diseases. -, -, -. Ottawa, Canada: Canadian Medical Association.

  • McCombe, P. A., Clark, P., Pollard, J. D., Hammond, S. R. and McLeod, J. G. (1984). ALPHA-1 Antitrypsin Phenotypes in Guillain-Barre Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy, and Multiple Sclerosis. You have full text access to this content 109th Annual Meeting of the American Neurological Association, Baltimore MD, 7-10 October 1984. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ana.410160128

  • McCombe, P., Lavin, M. F., Campbell, B., Mansbridge, J. N. and Kidson, C. (1975). Repair of ultraviolet irradiation damage in mouse neuroblastoma cells: a model for post mitotic cell repair. Australian Biochemical Society Annual General Meeting, -, -. Kent Town, SA, Australia: Australian Society for Biochemistry and Molecular Biology.

Edited Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision