The University of Queensland

Neuroinflammation in Huntington’s

Lee, John D., Lo, Martin W., Fung, Jenny N. T. and Woodruff, Trent M. (2022). Neuroinflammation in Huntington’s. Neurodegenerative Diseases Biomarkers. (pp. 215-233) edited by Philip V. Peplow, Bridget Martinez and Thomas A. Gennarelli. New York, NY, United States: Springer US. doi: 10.1007/978-1-0716-1712-0_9

Genetic biomarkers for endometriosis

Lee, Sang Hong, Sapkota, Yadav, Fung, Jenny and Montgomery, Grant W. (2017). Genetic biomarkers for endometriosis. Biomarkers for Endometriosis: State of the Art. (pp. 83-93) edited by Thomas D'Hooghe. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-59856-7_5

Endometrial cancer: diagnosis, treatment and prevention

Fung, Jenny N.T. and Chen, Chen (2012). Endometrial cancer: diagnosis, treatment and prevention. Horizons in cancer research. Volume 49. (pp. 1-32) edited by Hiroto S. Watanabe. Hauppauge, NY, USA: Nova Publishers.

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Rahmioglu, Nilufer, Mortlock, Sally, Ghiasi, Marzieh, Møller, Peter L., Stefansdottir, Lilja, Galarneau, Geneviève, Turman, Constance, Danning, Rebecca, Law, Matthew H., Sapkota, Yadav, Christofidou, Paraskevi, Skarp, Sini, Giri, Ayush, Banasik, Karina, Krassowski, Michal, Lepamets, Maarja, Marciniak, Błażej, Nõukas, Margit, Perro, Danielle, Sliz, Eeva, Sobalska-Kwapis, Marta, Thorleifsson, Gudmar, Topbas-Selcuki, Nura F., Vitonis, Allison, Westergaard, David, Arnadottir, Ragnheidur, Burgdorf, Kristoffer S., Campbell, Archie, Cheuk, Cecilia S. K. ... The 23andMe Research Team (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics, 55 (3), 423-436. doi: 10.1038/s41588-023-01323-z

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2022). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 1-16. doi: 10.1038/s41380-022-01831-0

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174

Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism

McDonald, Tanya S., Kumar, Vinod, Fung, Jenny N., Woodruff, Trent M. and Lee, John D. (2021). Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism. The FASEB Journal, 35 (7) e21707, e21707. doi: 10.1096/fj.202002450r

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

Holdsworth-Carson, Sarah J., Churchill, Molly, Donoghue, Jacqueline F., Mortlock, Sally, Fung, Jenny N., Sloggett, Clare, Chung, Jessica, Cann, Leonie, Teh, Wan Tinn, Campbell, Katie-Rose, Luwor, Rodney, Healey, Martin, Montgomery, Grant, Girling, Jane E. and Rogers, Peter A. W. (2021). Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis. Molecular Human Reproduction, 27 (3) gaab010. doi: 10.1093/molehr/gaab010

An immunoregulatory role for complement receptors in murine models of breast cancer

Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002

Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium

Marla, S., Mortlock, S., Houshdaran, S., Fung, J., McKinnon, B., Holdsworth-Carson, S. J., Girling, J. E., Rogers, P. A. W., Giudice, L. C. and Montgomery, G. W. (2021). Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium. Molecular Human Reproduction, 27 (1) gaaa082. doi: 10.1093/molehr/gaaa082

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis

Lee, John D., McDonald, Tanya S., Fung, Jenny N. T. and Woodruff, Trent M. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9

Tissue specific regulation of transcription in endometrium and association with disease

Mortlock, Sally, Kendarsari, Raden I., Fung, Jenny N., Gibson, Greg, Yang, Fei, Restuadi, Restuadi, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Lukowski, Samuel W., Healey, Martin, Qi, Ting, Rogers, Peter A. W., Yang, Jian, McKinnon, Brett and Montgomery, Grant W. (2020). Tissue specific regulation of transcription in endometrium and association with disease. Human Reproduction, 35 (2), 377-393. doi: 10.1093/humrep/dez279

Obesity does not alter endometrial gene expression in women with endometriosis

Holdsworth-Carson, Sarah J, Chung, Jessica, Sloggett, Clare, Mortlock, Sally, Fung, Jenny N., Montgomery, Grant W., Dior, Uri P., Healey, Martin, Rogers, Peter A.W. and Girling, Jane E. (2020). Obesity does not alter endometrial gene expression in women with endometriosis. Reproductive BioMedicine Online, 41 (1), 113-118. doi: 10.1016/j.rbmo.2020.03.015

Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

Mortlock, Sally, Restuadi, Restuadi, Levien, Rupert, Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Zhu, Zhihong, Qi, Ting, Wu, Yang, Lukowski, Samuel W., Rogers, Peter A. W., Yang, Jian, McRae, Allan F., Fung, Jenny N. and Montgomery, Grant W. (2019). Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clinical Epigenetics, 11 (1) 49, 49. doi: 10.1186/s13148-019-0648-7

Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes

Holdsworth-Carson, S. J., Colgrave, E. M., Donoghue, J. F., Fung, J. N., Churchill, M. L., Mortlock, S., Paiva, P., Healey, M., Montgomery, G. W., Girling, J. E. and Rogers, P. A. W. (2019). Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes. MHR: Basic science of reproductive medicine, 25 (4), 194-205. doi: 10.1093/molehr/gaz006

Complex genetics of female fertility

Gajbhiye, Rahul, Fung, Jenny N. and Montgomery, Grant W. (2018). Complex genetics of female fertility. npj Genomic Medicine, 3 (1) 29, 29. doi: 10.1038/s41525-018-0068-1

Identification of nine new susceptibility loci for endometrial cancer

O’Mara, Tracy A., Glubb, Dylan M., Amant, Frederic, Annibali, Daniela, Ashton, Katie, Attia, John, Auer, Paul L., Beckmann, Matthias W., Black, Amanda, Bolla, Manjeet K., Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Buchanan, Daniel D., Burwinkel, Barbara, Chang-Claude, Jenny, Chanock, Stephen J., Chen, Chu, Chen, Maxine M., Cheng, Timothy H. T., Clarke, Christine L., Clendenning, Mark, Cook, Linda S., Couch, Fergus J., Cox, Angela, Crous-Bous, Marta, Czene, Kamila, Day, Felix, Dennis, Joe ... Thompson, Deborah J. (2018). Identification of nine new susceptibility loci for endometrial cancer. Nature Communications, 9 (1) 3166, 3166. doi: 10.1038/s41467-018-05427-7

Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome

Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W. and Montgomery, Grant W (2018). Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports, 8 (1) 11424, 11424. doi: 10.1038/s41598-018-29462-y

Genetics of endometriosis: state of the art on genetic risk factors for endometriosis

Fung, Jenny N. and Montgomery, Grant W. (2018). Genetics of endometriosis: state of the art on genetic risk factors for endometriosis. Best Practice & Research: Clinical Obstetrics & Gynaecology, 50, 61-71. doi: 10.1016/j.bpobgyn.2018.01.012

The association of sonographic evidence of adenomyosis with severe endometriosis and gene expression in eutopic endometrium

Dior, Uri P., Nisbet, Debbie, Fung, Jenny N., Foster, Grant, Healey, Martin, Montgomery, Grant W., Rogers, Peter A.W., Holdsworth-Carson, Sarah J. and Girling, Jane E. (2018). The association of sonographic evidence of adenomyosis with severe endometriosis and gene expression in eutopic endometrium. Journal of Minimally Invasive Gynecology, 26 (5), 941-948. doi: 10.1016/j.jmig.2018.09.780

Genetic risk factors for endometriosis

Fung, Jenny N., Sapkota, Yadav, Nyholt, Dale R. and Montgomery, Grant W. (2017). Genetic risk factors for endometriosis. Journal of Endometriosis and Pelvic Pain Disorders, 9 (2), 69-76. doi: 10.5301/je.5000273

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Lee, John D., Kumar, Vinod, Fung, Jenny N. T., Ruitenberg, Marc J., Noakes, Peter G. and Woodruff, Trent M. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730

The genetic regulation of transcription in human endometrial tissue

Fung, Jenny N., Girling, Jane E., Lukowski, Samuel W., Sapkota, Yadav, Wallace, Leanne, Holdsworth-Carson, Sarah J., Henders, Anjali K., Healey, Martin, Rogers, Peter A. W., Powell, Joseph E. and Montgomery, Grant W. (2017). The genetic regulation of transcription in human endometrial tissue. Human Reproduction, 32 (4), 893-904. doi: 10.1093/humrep/dex006

Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339

Powell, Joseph E., Fung, Jenny N., Shakhbazov, Konstantin, Sapkota, Yadav, Cloonan, Nicole, Hemani, Gibran, Hillman, Kristine M., Kaufmann, Susanne, Luong, Hien T., Bowdler, Lisa, Painter, Jodie N., Holdsworth-Carson, Sarah J., Visscher, Peter M., Dinger, Marcel E., Healey, Martin, Nyholt, Dale R., French, Juliet D., Edwards, Stacey L., Rogers, Peter A. W. and Montgomery, Grant W. (2016). Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339. Human Molecular Genetics, 25 (22), 5046-5058. doi: 10.1093/hmg/ddw320

Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide

Seim, Inge, Jeffery, Penny L., Thomas, Patrick B., Walpole, Carina M., Maugham, Michelle, Fung, Jenny N. T., Yap, Pei-Yi, O'Keeffe, Angela J., Lai, John, Whiteside, Eliza J., Herington, Adrian C. and Chopin, Lisa K. (2016). Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide. Endocrine, 52 (3), 609-617. doi: 10.1007/s12020-015-0848-7

Endometrial vezatin and its association with endometriosis risk

Holdsworth-Carson, Sarah J., Fung, Jenny N., Luong, Hien T. T., Sapkota, Yadav, Bowdler, Lisa M., Wallace, Leanne, Teh, Wan Tinn, Powell, Joseph E., Girling, Jane E., Healey, Martin, Montgomery, Grant W. and Rogers, Peter A. W. (2016). Endometrial vezatin and its association with endometriosis risk. Human Reproduction, 31 (5), 999-1013. doi: 10.1093/humrep/dew047

Independent replication and meta-analysis for endometriosis risk loci

Sapkota, Yadav, Fassbender, Amelie, Bowdler, Lisa, Fung, Jenny N., Peterse, Danielle, O, Dorien, Montgomery, Grant W., Nyholt, Dale R. and D'Hooghe, Thomas M. (2015). Independent replication and meta-analysis for endometriosis risk loci. Twin Research and Human Genetics, 18 (5), 518-525. doi: 10.1017/thg.2015.61

Functional evaluation of genetic variants associated with endometriosis near GREB1

Fung, Jenny N., Holdsworth-Carson, Sarah J., Sapkota, Yadav, Zhao, Zhen Zhen, Jones, Lincoln, Girling, Jane E., Paiva, Premila, Healey, Martin, Nyholt, Dale R., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Functional evaluation of genetic variants associated with endometriosis near GREB1. Human Reproduction, 30 (5), 1263-1275. doi: 10.1093/humrep/dev051

Identifying the biological basis of GWAS hits for endometriosis

Fung, Jenny N., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Identifying the biological basis of GWAS hits for endometriosis. Biology of Reproduction, 92 (4) 87. doi: 10.1095/biolreprod.114.126458

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines

Whiteside, Eliza J., Seim, Inge, Pauli, Jana P., O'Keeffe, Angela J., Thomas, Patrick B., Carter, Shea L., Walpole, Carina M., Fung, Jenny N. T., Josh, Peter, Herington, Adrian C. and Chopin, Lisa K. (2013). Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines. International Journal of Oncology, 43 (2), 566-574. doi: 10.3892/ijo.2013.1969

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin

Seim, Inge, Jeffery, Penny L., de Amorim, Laura, Walpole, Carina M., Fung, Jenny, Whiteside, Eliza J., Lourie, Rohan, Herington, Adrian C. and Chopin, Lisa K. (2013). Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin. Reproductive Biology and Endocrinology, 11 (1) 70, 70.1-70.9. doi: 10.1186/1477-7827-11-70

Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo

Fung, Jenny N. T., Jeffery, Penny L., Lee, John D., Seim, Inge, Roche, Deborah, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2013). Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 305 (2), E305-E313. doi: 10.1152/ajpendo.00156.2013

Expression and in vitro functions of the ghrelin axis in endometrial cancer

Fung, Jenny N. T., Seim, Inge, Wang, Dengfeng, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2010). Expression and in vitro functions of the ghrelin axis in endometrial cancer. Hormone and Cancer, 1 (5), 245-255. doi: 10.1007/s12672-010-0047-1

TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway

Wang, Dengfeng, Fung, Jenny Nga Ting Fung, Tuo, Ya, Hu, Lina and Chen, Chen (2010). TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway. Cancer Letters, 294 (1), 91-100. doi: 10.1016/j.canlet.2010.01.027

Expression and Cellular Localization of Endometriosis Risk Gene Long Intergenic Non-Coding RNA 339 (LINC00339)

Holdsworth-Carson, Sarah J., Girling, Jane, Cann, Leonie, Healey, Martin, Fung, Jenny N., Montgomery, Grant and Rogers, Peter (2019). Expression and Cellular Localization of Endometriosis Risk Gene Long Intergenic Non-Coding RNA 339 (LINC00339). 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA United States: Sage.

Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes

Holdsworth-Carson, Sarah J., Donoghue, Jacqueline, Colgrave, Eliza, Fung, Jenny N., Churchill, Molly, Healey, Martin, Montgomery, Grant, Girling, Jane and Rogers, Peter (2019). Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.

Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium

Mortlock, Sally, Fung, Jenny N., Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Lukowski, Samuel W., McKinnon, Brett D., Yang, Jian, McRae, Allan, Rogers, Peter A. W. and Montgomery, Grant W. (2019). Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.

Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis

Holdsworth-Carson, Sarah J., Chung, Jessica, Healey, Martin, Fung, Jenny N., Montgomery, Grant, Rogers, Peter and Girling, Jane (2019). Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019 . Thousand Oaks, CA, United States: Sage.

Dynamic changes in gene regulation in human endometrium

Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Healey, Martin, Rogers, Peter A. W. and Montgomery, Grant W. (2018). Dynamic changes in gene regulation in human endometrium. 65th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), San Diego CA, United States, 6-10 March 2018. Thousand Oaks, CA United States: Sage Publications.

Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.

Montgomery, Grant W., Fung, Jenny N., Holdsworth-Carson, Sarah J., Girling, Jane E., Franch, Juliet D., Edwards, Stacey L., Powell, Joseph E. and Rogers, Peter A. W. (2017). Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.

Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.

Rogers, Peter A. W., Holdsworth-Carson, Sarah J., Fung, Jenny N., Colgrave, Eliza M., Paiva, Premila, Girling, Jane E. and Montgomery, Grant W. (2017). Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.

Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo

Fung, Nga Ting Jenny (2012). Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo. PhD Thesis, School of Biomedical Sciences, The University of Queensland.