The University of Queensland

Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo

Lim, Ye-Wheen, Lo, Harriet P., Hall, Thomas E. and Parton, Robert G. (2020). Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo. Caveolae: methods and protocols. (pp. 175-187) edited by Cedric M. Blouin. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0732-9_16

Cell surface plasticity in response to shape change in the whole organism

Hall, Thomas E., Ariotti, Nicholas, Lo, Harriet P., Rae, James, Ferguson, Charles, Martel, Nick, Lim, Ye-Wheen, Giacomotto, Jean and Parton, Robert G. (2023). Cell surface plasticity in response to shape change in the whole organism. Current Biology, 33 (19), 4276-4284.e4. doi: 10.1016/j.cub.2023.08.068

Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2

Wu, Yeping, Lim, Ye-Wheen, Stroud, David A., Martel, Nick, Hall, Thomas E., Lo, Harriet P., Ferguson, Charles, Ryan, Michael T., McMahon, Kerrie-Ann and Parton, Robert G. (2023). Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2. Developmental Cell, 58 (5), 376-397.e4. doi: 10.1016/j.devcel.2023.02.004

Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle

Lamboley, Cedric R., Pearce, Luke, Seng, Crystal, Meizoso-Huesca, Aldo, Singh, Daniel P., Frankish, Barnaby P., Kaura, Vikas, Lo, Harriet P., Ferguson, Charles, Allen, Paul D., Hopkins, Philip M., Parton, Robert G., Murphy, Robyn M., van der Poel, Chris, Barclay, Christopher J. and Launikonis, Bradley S. (2021). Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle. Science Advances, 7 (44) eabi7166, 1-15. doi: 10.1126/sciadv.abi7166

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle

Lo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065

Proximity dependent biotin labelling in zebrafish for proteome and interactome profiling

Xiong, Zherui, Lo, Harriet P., McMahon, Kerrie-Ann, Parton, Robert G. and Hall, Thomas E. (2021). Proximity dependent biotin labelling in zebrafish for proteome and interactome profiling. Bio-protocol, 11 (19) e4178, e4178. doi: 10.21769/BIOPROTOC.4178

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

McMahon, Kerrie-Ann, Stroud, David A., Gambin, Yann, Tillu, Vikas, Bastiani, Michele, Sierecki, Emma, Polinkovsky, Mark E., Hall, Thomas E., Gomez, Guillermo A., Wu, Yeping, Parat, Marie-Odile, Martel, Nick, Lo, Harriet P., Khanna, Kum Kum, Alexandrov, Kirill, Daly, Roger, Yap, Alpha, Ryan, Michael T. and Parton, Robert G. (2021). Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response. eLife, 10 e61407, 1-35. doi: 10.7554/elife.61407

In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish

Xiong, Zherui, Lo, Harriet P., McMahon, Kerrie-Ann, Martel, Nick, Jones, Alun, Hill, Michelle M., Parton, Robert G. and Hall, Thomas E. (2021). In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish. eLife, 10 e64631, 1-21. doi: 10.7554/elife.64631

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117

In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation

Hall, Thomas E., Martel, Nick, Ariotti, Nicholas, Xiong, Zherui, Lo, Harriet P., Ferguson, Charles, Rae, James, Lim, Ye-Wheen and Parton, Robert G. (2020). In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation. Nature Communications, 11 (1) 3711, 3711. doi: 10.1038/s41467-020-17486-w

A variable undecad repeat domain in cavin1 regulates caveola formation and stability

Tillu, Vikas A., Lim, Ye-Wheen, Kovtun, Oleksiy, Mureev, Sergey, Ferguson, Charles, Bastiani, Michele, McMahon, Kerrie-Ann, Lo, Harriet P., Hall, Thomas E., Alexandrov, Kirill, Collins, Brett M. and Parton, Robert G. (2018). A variable undecad repeat domain in cavin1 regulates caveola formation and stability. EMBO Reports, 19 (9) e45775. doi: 10.15252/embr.201845775

Caveolae protect notochord cells against catastrophic mechanical failure during development

Lim, Ye-Wheen, Lo, Harriet P., Ferguson, Charles, Martel, Nick, Giacomotto, Jean, Gomez, Guillermo A., Yap, Alpha S., Hall, Thomas E. and Parton, Robert G. (2017). Caveolae protect notochord cells against catastrophic mechanical failure during development. Current Biology, 27 (13), 1968-1981.e7. doi: 10.1016/j.cub.2017.05.067

A plasmid library of full-length zebrafish rab proteins forcell biology

Hall, Thomas E., Martel, Nick, Lo, Harriet P., Xiong, Zherui and Parton, Robert G. (2017). A plasmid library of full-length zebrafish rab proteins forcell biology. Cellular Logistics, 7 (1), 1-5. doi: 10.1080/21592799.2017.1301151

Mechanoprotection by skeletal muscle caveolae

Lo, Harriet P., Hall, Thomas E. and Parton, Robert G. (2016). Mechanoprotection by skeletal muscle caveolae. BioArchitecture, 6 (1), 22-27. doi: 10.1080/19490992.2015.1131891

The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

Lo, Harriet P., Nixon, Susan Jane, Hall, Thomas Edward, Cowling, Belinda Simone, Ferguson, Charles, Morgan, Garry Patrick, Schieber, Nicole Louise, Fernandez-Rojo, Manuel Alejandro, Bastiani, Michele, Floetenmeyer, Matthias, Martel, Nick, Laporte, Jocelyn, Pilch, Paul F. and Parton, Robert (2015). The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. The Journal of Experimental Medicine, 212 (10), 833-849. doi: 10.1084/jem.21210oia80

The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

Lo, Harriet P., Nixon, Susan J., Hall, Thomas E., Cowling, Belinda S., Ferguson, Charles, Morgan, Garry P., Schieber, Nicole L., Fernandez-Rojo, Manuel A., Bastiani, Michele, Floetenmeyer, Matthias, Martel, Nick, Laporte, Jocelyn, Pilch, Paul F. and Parton, Robert G. (2015). The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. Journal of Cell Biology, 210 (5), 833-849. doi: 10.1083/jcb.201501046

MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line

Faggi, Fiorella, Codenotti, Silvia, Poliani, Pietro Luigi, Cominelli, Manuela, Chiarelli, Nicola, Colombi, Marina, Vezzoli, Marika, Monti, Eugenio, Bono, Federica, Tulipano, Giovanni, Fiorentini, Chiara, Zanola, Alessandra, Lo, Harriet P., Parton, Robert G., Keller, Charles and Fanzani, Alessandro (2015). MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. PLoS One, 10 (6) e0130287, e0130287-e0130287. doi: 10.1371/journal.pone.0130287

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis

Chaudhary, Natasha, Gomez, Guillermo A., Howes, Mark T., Lo, Harriet P., McMahon, Kerrie-Ann, Rae, James A., Schieber, Nicole L., Hill, Michelle M., Gaus, Katharina, Yap, Alpha S. and Parton, Robert G. (2014). Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis. PLoS Biology, 12 (4) e1001832, e1001832.1-e1001832.20. doi: 10.1371/journal.pbio.1001832

Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling

Fernández Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013). Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 (2), 238-247. doi: 10.1016/j.celrep.2013.06.017

Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers

Jayasinghe, Isuru D., Lo, Harriet P., Morgan, Garry P., Baddeley, David, Parton, Robert G., Soeller, Christian and Launikonis, Bradley S. (2013). Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers. Biophysical Journal, 104 (11), L19-L21. doi: 10.1016/j.bpj.2013.04.029

Flexible and general synthesis of functionalized phosphoisoprenoids for the study of prenylation in vivo and in vitro

Das, Debapratim, Tnimov, Zakir, Nguyen, Uyen T. T., Thimmaiah, Govindaraju, Lo, Harriet, Abankwa, Daniel, Wu, Yaowen, Goody, Roger S., Waldmann, Herbert and Alexandrov, Kirill (2012). Flexible and general synthesis of functionalized phosphoisoprenoids for the study of prenylation in vivo and in vitro. ChemBioChem, 13 (5), 674-683. doi: 10.1002/cbic.201100733

High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids

Rae, James, Fontaine, Frank, Salim, Angela A., Lo, Harriet P., Capon, Robert J., Parton, Robert G. and Martin, Sally (2011). High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids. PLoS One, 6 (8) e22868, e22868.1-e22868.13. doi: 10.1371/journal.pone.0022868

Mosaic caveolin-3 expression in acquired rippling muscle disease without evidence of myasthenia gravis or acetylcholine receptor autoantibodies

Lo, Harriet P., Bertini, Enrico, Mirabella, Massimiliano, Domazetovska, Ana, Dale, Russell C., Petrini, Stefania, D'Amico, Adele, Valente, Enza Maria, Barresi, Rita, Roberts, Marl, Tozzi, Giulia, Tasca, Giorgio, Cooper, Sandra T., Straub, Volker and North, Kathryn N. (2011). Mosaic caveolin-3 expression in acquired rippling muscle disease without evidence of myasthenia gravis or acetylcholine receptor autoantibodies. Neuromuscular Disorders, 21 (3), 194-203. doi: 10.1016/j.nmd.2010.11.015

Reduced plasma membrane expression of dysferlin mutants is attributed to accelerated endocytosis via a syntaxin-4-associated pathway

Evesson, Frances J., Peat, Rachel A., Lek, Angela, Brilot, Fabienne, Lo, Harriet P., Dale, Russell C., Parton, Robert G., North, Kathryn N. and Cooper, Sandra T. (2010). Reduced plasma membrane expression of dysferlin mutants is attributed to accelerated endocytosis via a syntaxin-4-associated pathway. Journal of Biological Chemistry, 285 (37), 28529-28539. doi: 10.1074/jbc.M110.111120

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

Bastiani, M, Liu, L, Hill, M. M., Jedrychowski, M. P., Nixon, S. J., Lo, H. P., Abankwa, D, Luetterforst, R, Fernandez-Rojo, M, Breen, M. R., Gygi, S. P., Vinten, J, Walser, P. J., North, K. N., Hancock, J. F., Pilch, P. F. and Parton, R. G. (2009). MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. The Journal of Cell Biology, 185 (7), 1259-1273. doi: 10.1083/jcb.200903053

A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos

Nixon, S. J., Webb, R. I., Floetenmeyer, M., Schieber, N., Lo, H. P. and Parton, R.G. (2009). A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos. Traffic, 10 (2), 131-136. doi: 10.1111/j.1600-0854.2008.00859.x

Muscular dystrophy associated with α-dystroglycan deficiency in Sphynx and Devon Rex cats

Martin, Paul T., Shelton, G. Diane, Dickinson, Peter J., Sturges, Beverly K., Xua, Rui, LeCouteur, Richard A., Guo, Ling T., Grahn, Robert A., Lo, Harriet P., Northe, Kathryn N., Malik, Richard, Engvallg, Eva and Lyons, Leslie A. (2008). Muscular dystrophy associated with α-dystroglycan deficiency in Sphynx and Devon Rex cats. Neuromuscular Disorders, 18 (12), 942-952. doi: 10.1016/j.nmd.2008.08.002

Changes in skeletal muscle expression of AQP1 and AQP4 in dystrophinopathy and dysferlinopathy patients

Au, Carol G., Butler, Tanya L., Egan, Jonathan R., Cooper, Sandra T., Lo, Harriet P., Compton, Alison G., North, Kathryn N. and Winlaw, David S. (2008). Changes in skeletal muscle expression of AQP1 and AQP4 in dystrophinopathy and dysferlinopathy patients. Acta Neuropathologica, 116 (3), 235-246. doi: 10.1007/s00401-008-0369-z

Limb–girdle muscular dystrophy: Diagnostic evaluation, frequency and clues to pathogenesis

Lo, Harriet P., Cooper, Sandra T., Evesson, Frances J., Seto, Jane T., Chiotis, Maria, Tay, Valerie, Compton, Alison G., Cairns, Anita G., Corbett, Alistair, MacArthur, Daniel G., Yang, Nan, Reardon, Katrina and North, Kathryn N. (2008). Limb–girdle muscular dystrophy: Diagnostic evaluation, frequency and clues to pathogenesis. Neuromuscular Disorders, 18 (1), 34-44. doi: 10.1016/j.nmd.2007.08.009

Dystrophinopathy carrier determination and detection of protein deficiencies in muscular dystrophy using lentiviral MyoD-forced myogenesis

Cooper, Sandra T., Kizana, Eddy, Yates, Jonathon D., Lo, Harriet P., Yang, Nan, Wu, Zhan H., Alexander, Ian E. and North, Kathryn N. (2007). Dystrophinopathy carrier determination and detection of protein deficiencies in muscular dystrophy using lentiviral MyoD-forced myogenesis. Neuromuscular Disorders, 17 (4), 276-284. doi: 10.1016/j.nmd.2006.12.010

Rippling muscle disease

Roberts, Helene L., Day, Bruce, Lo, Harriet, McLean, Catriona and North, Kathryn (2006). Rippling muscle disease. Journal of Clinical Neuroscience, 13 (5), 576-578. doi: 10.1016/j.jocn.2005.06.015

Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3

Hernandez-Deviez, D. J., Martin, S., Laval, S. H., Lo, H. P., Cooper, S. T., North, K. N., Bushby, K. and Parton, RG (2006). Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3. Human Molecular Genetics, 15 (1), 129-142. doi: 10.1093/hmg/ddi434

Expression of Aquaporin 1 in Human Cardiac and Skeletal Muscle

Au, Carol G., Cooper , Sandra T., Lo, Harriet P., Compton, Alison G., Yang, Nan, Wintour, E. Marelyn, North, Kathryn N. and Winlaw, David S. (2004). Expression of Aquaporin 1 in Human Cardiac and Skeletal Muscle. Journal of Molecular and Cellular Cardiology, 36 (5), 655-666. doi: 10.1016/j.yjmcc.2004.01.009

Single Section Western Blot: Improving the Molecular Diagnosis of the Muscular Dystrophies.

Cooper, Sandra T., Lo, Harriet P. and North, Kathryn N. (2003). Single Section Western Blot: Improving the Molecular Diagnosis of the Muscular Dystrophies.. Neurology, 61 (1), 93-97. doi: 10.1212/01.WNL.0000069460.53438.38

Diffusion weighted imaging of zebrafish embryos using dedicated radio frequency coils

Ariens, Miriam, Ullmann, Jeremy, Kurniawan, Nyoman, Lo, Harriet, Reutens, David and Vegh, Viktor (2012). Diffusion weighted imaging of zebrafish embryos using dedicated radio frequency coils. 20th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Melbourme, VIC, Australia, 5-11 May 2012.