Associate Professor Ingrid Winkler

Honorary Associate Professor

Mater Research Institute-UQ
Faculty of Medicine

Overview

Associate Professor Ingrid Winkler is a Senior Research Fellow and head of the Stem Cells and Cancer group at Mater Research, Brisbane, Australia.

Ingrid Winkler’s research focuses on understanding how micro-environments protect and instruct Stem Cells. Her innovative research has already led to several discoveries, such as a novel strategy to protect normal Haematopoietic Stem Cells from chemotherapy or radiation damage. Research which may lead to a novel strategy to i. Potentially alleviate the life-threatening side-effects of cancer therapies, and ii. New ways to sensitise cancer cells to standard cancer therapy.

Over the course of her career, Dr Winkler has produced 49 peer-reviewed articles, including a recent landmark study in Nature Medicine 2012, describing a key component of the bone marrow vascular niche (E-selectin) in regulating Haematopoietic Stem Cell self-renewal and chemo-sensitivity and last year her research was recognized to be among ‘Ten of the Best Research Projects’in Australia by the National Health & Medical Research Council.

Research Impacts

Over the course of her career, Dr Winkler has produced 49 peer-reviewed articles, including a recent landmark study in Nature Medicine 2012, describing a key component of the bone marrow vascular niche (E-selectin) in regulating Haematopoietic Stem Cell self-renewal and chemo-sensitivity and last year her research was recognized to be among ‘Ten of the Best Research Projects’in Australia by the National Health & Medical Research Council.

Publications

  • Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018) Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 7: 735-749. doi:10.1182/blood-2018-01-829663

  • Levesque, Jean-Pierre, Jacobsen, Rebecca N. and Winkler, Ingrid G. (2017). The role of mesenchymal stem cells in hematopoiesis. In Kerry Atkinson (Ed.), The biology and therapeutic application of mesenchymal cells (pp. 467-480) Hoboken, NJ, United States: John Wiley and Sons. doi:10.1002/9781118907474.ch32

  • Tay, Joshua, Levesque, Jean‑Pierre and Winkler, Ingrid G. (2016) Cellular players of hematopoietic stem cell mobilization in the bone marrow niche. International Journal of Hematology, 105 2: 1-12. doi:10.1007/s12185-016-2162-4

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Supervision

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Publications

Book Chapter

Journal Article

Conference Publication

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

Completed Supervision