You searched for: cancer
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Primarily endometrial cancer… Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer… Identifying the regulatory targets of common endometrial cancer risk variants… We and our international Endometrial Cancer Association Consortium collaborators have identified… Gynaecological cancer genetics… -enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research… Excessive exposure to estrogen is a well-established risk factor for endometrial cancer (EC…
After completing his BSc and MSc (Hons) at the University of Canterbury (NZ), Dylan worked for five years as a Research Scientist at Antisoma Research Limited (London, UK), developing antibody-enzyme fusion proteins for cancer therapy. He returned to New Zealand to carry out his PhD research into an …
Large numbers of germline genetic variants have been found to associate with disease. A major roadblock in our understanding of how genetics contribute to disease has been a lack of knowledge of the molecular effects of variants. Thus, the aim of my research program is to use genetic analyses to ass …
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Using published datasets, and tissue donated by Brisbane breast cancer patients, we're trying to… Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R… Development of new theranostic agents for metastatic breast cancer surveillance and treatment… Molecular validation of autofluorescence and narrow band imaging of oral cancer resection margins… Most of the time, treatments for early breast cancer successfully prevent metastatic spread, but… Biomarkers of triple-negative breast cancer progression and response to therapy… cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research… BRCA1 is a breast cancer susceptibility gene that is down-regulated in the majority of cases of…
Dr Jodi Saunus is a senior fellow who specialises in translational research on metastatic breast cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research in 2022 to help facilitate patient-focused research at the interface of biomedical R&D and clinical pra …
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Melanoma is the fourth most common cancer with >11,000 Australians diagnosed each year resulting… transcriptome, methylation) as well as Spatial Profiling to greater understand the early hallmarks of pre-skin cancer development.… Single nucleotide polymorphisms in obesity-related genes and the risk of esophageal cancers… Laser capture microdissection to empower cancer discoveries, improve diagnosis, treatment and outcomes in amyloidosis patients… development a Genomics Atlas of pre-skin cancer lesions. If you are interested to hear… Genomics Atlas of pre-skin cancer lesions… biomarkers for melanoma progression and the development a Genomics Atlas of pre-skin cancer… Epigenetic gene inactivation of tumour suppressor genes underlies several human cancers. The…
Dr Mitchell Stark is a molecular biologist and Group Leader/Senior Research Fellow from the Dermatology Research Centre (DRC) based at the Frazer Institute. His group has extensive experience in microRNA biology and biomarker discovery, next-generation sequencing, bioinformatics, and functional anal …
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Development of novel therapeutics for melanoma and non-melanoma cancer… Hypoxia-induced stress responses in cancer and cancer stem cells… Skin Cancer… ) promotes stress and death of the organism. However, cancer cells have evolved adaptive mechanisms to…
Researcher Biography
Dr Snehlata Kumari is the head of skin inflammation and immunity laboratory at the Frazer Institute, the University of Queensland in Brisbane, Australia. She is a board member of the Australasian Society for Dermatology Research (ASDR).
After PhD and post-doctoral training in …
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extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer… Hypoxia increases the exosome release from ovarian cancer cells and promotes the epithelial-mesenchymal transition of target cells… Extracellular vesicles and ovarian cancer… UniQuest-INOVIQ Umbrella Research and Option Agreement: Exosome based ovarian cancer screening… realistic that a clinically useful antenatal screening test can be developed. Unlike diseases such as cancer… Assays for clinically relevant complications (including ovarian cancers, and obstetrical syndromes… Pancreatic cancer is the fourth most common cause of death due to cancer in the world. It is known…
I am Professor, NHMRC Investigator Fellow (EL2) and group leader (Exosome Biology Laboratory) at UQ Centre for Clinical Research. I am nationally and internationally (>20 invitations to international meetings in the last 5 years) acknowledged key opinion leader on Extracellular Vesicle (rated 3th w …
My research program focused on obstetrics and gynaecology, and it has investigated the release of extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer progression, and their utility as a biomarker for a wide range of pregnancy complications, and ovarian cancer. …
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Role of the growth hormone–IGF-1 axis in cancer… Hardy Brothers Scholarship for Research in Blood Cancer at the UQ Diamantina Institute… Journal Cancers and Human Cell. He was previously a committee member of Australian Early-Mid Career… transformation and cancer can occur in response to autocrine activation of the receptor. Advances in…
Dr Andrew Brooks is the Group Leader of the Cytokine Receptor Signalling Group at the University of Queensland Diamantina Institute (UQ DI) within the Translational Research Institute. Andrew completed his Honours research on Flaviviruses in 1996 at the Department of Microbiology and Immunology at J …
Quality of Research Outputs
In the last 10 years I have published in journals including Science, Nature Cell Biology, Blood, Oncogene, J Immunol, and Nature Reviews. I have over 1000 citations (Web of Knowledge or over 1500 Google Scholar) with an h-index of 16 (Web of Knowledge) or 19 (Google Scho …
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Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles… . The procedure was done to treat ulcerative pancolitis complicated by colon cancer. She had a well…
Associate Professor Jakob Begun is the IBD Group leader in the Immunity, Infection, and Inflammation Program at Mater Research University of Queensalnd, and has a basic and translational laboratory at the Translational Research Institute in Brisbane. He is an Associate Professor in the University of …
Inflammatory bowel disease(IBD) is a complex disease with genetic and environmental triggers. The microbiota is one of the biggest environmental contributors and interest in its impact on human health and disease is a growing. Studies in IBD have led the way in identifying disease associated microbi …
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Local doxorubicin delivery via 3D‐printed porous scaffolds reduces systemic cytotoxicity and breast cancer recurrence in mice… projects on cancer and bone tissue engineering. Dr Shafiee has developed innovative tissue engineered… The concept of using macroscale porous scaffolds as local drug reservoirs to prevent cancer…
Dr Abbas Shafiee is a tissue engineering & regenerative medicine scientist interested in translational cell-based and tissue engineering strategies to treat human diseases.
Dr Shafiee completed his PhD in Professor Kiarash Khosrotehrani’s laboratory on stem cell biology. His research career durin …
My research program has been devoted to understanding human tissue development to develop advanced technologies for tissue regeneration.
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