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Munc18 controls exocytosis. This research will be important for understanding how neurons… The basis for movement of molecules between cellular organelles essential for cell homeostasis.… Applications of isothermal titration calorimetry in pure and applied research—survey of the literature from 2010… UQ's Institute for Molecular Bioscience. He was a lead investigator in the seminal structural… and recommends areas for future research to advance practically useful algorithms for protein science.…
Brett Collins is an NHMRC Career Development Fellow and head of the Molecular Trafficking Lab at UQ's Institute for Molecular Bioscience. He was a lead investigator in the seminal structural studies of AP2, the protein adaptor molecule central to clathrin-mediated endocytosis, and has since defined …
Trafficking is essential for normal cellular function and is perturbed in many different diseases, notably Alzheimer’s and other neurological disorders, pathogen invasion, cancer and inflammation. A/Prof Collins is probing the fundamental mechanisms of membrane transport, through the application o …
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generate important new knowledge, train future scientific leaders in cutting edge research and promote Australian science internationally.… -cadherin interacts with the Arp2/3 complex to mark sites for actin assembly within cells. We are now… An interview with Alpha Yap, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia… NHMRC Research Fellowship (SRF B)… the group leader for Cadherin cell adhesion molecules, Epithelial morphogenesis & Cell locomotion research at the IMB.… learnt about this problem and identify open questions for future research.…
My group studies the role of cadherin cell adhesion molecules in morphogenesis and tumor development. E-cadherin is a key mediator of cell-cell recognition. It participates in tissue patterning and its dysfunction contributes to tumor progression and invasion.
Associate Professor Yap is the group l …
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danger responses for future basic research and commercial applications, and fundamental understanding of how animals flourish in a dangerous world.… Questions and Controversies in innate immune research: What is the physiological role of NLRP3?… , medical, materials science, and agricultural applications… publication list; (2) studies report for undergraduate and honours degree(s); and (3) a letter of motivation outlining your research interests.… Inflammation and Disease Research at the Institute for Molecular Bioscience (IMB), University of… The NIH-funded center for autophagy research named Autophagy, Inflammation, and Metabolism (AIM…
Professor Kate Schroder heads the Inflammasome Laboratory and is Director of the Centre for Inflammation and Disease Research at the Institute for Molecular Bioscience (IMB), University of Queensland, as an NHMRC Leadership Fellow. Kate’s graduate studies defined novel macrophage activation mechan …
Our research focuses on understanding how immune cells launch healthy inflammation to fight infection and unhealthy inflammation to promote disease. By understanding exactly how the body fights infection, we can help identify new drug targets or vaccines to combat infectious disease, which causes 13 …
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30/07/08-01/10/08 JAPAN RIKEN Brain Science Institute… mechanism provides a novel strategy for the treatment of epileptic seizures. (C) 2001 Elsevier Science Ltd. All rights reserved.…
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the control of inflammation. This research has profound implications for the therapeutic inhibition of PI3Ks in new receptor pathways.… accompanies many chronic diseases. Our research investigates the roles of TLR signalling regulators… Wellcome Senior Research Fellowship in Medical Science in Australia. Regulation of vesicle trafficking and secretion in epithelial cells… , inclusive and supportive culture for research and celebrate the many diverse and wonderful successes of Stow lab alumni.… roles in vesicle budding and vesicle trafficking can be proposed for these actin-based motors. (C) 1998 Elsevier Science B.V. All rights reserved.…
Professor Jennifer Stow is a molecular cell biologist, an NHMRC Leadership Fellow and head of the Protein Trafficking and Inflammation research laboratory in The University of Queensland’s Institute of Molecular Bioscience (IMB). Her previous leadership appointments include as Division Head and De …
Understanding how cells and molecules within our bodies function is essential for understanding and addressing diseases and other factors that affect our biology, such as genetics, environment, drugs and bugs. Cells contain remarkably complex pathways for trafficking, or moving proteins around, and …
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