Professor Kristofer Thurecht

NHMRC Career Dev Fel & Group Ldr

Centre for Advanced Imaging

Affiliate PRF & Group Leader

Australian Institute for Bioengineering and Nanotechnology
k.thurecht@uq.edu.au
+61 7 334 60344

Overview

Associate Professor Kris Thurecht is a National Health and Medical Research Council (NHMRC) Career Development Fellow (step 2) with appointments at AIBN and UQ’s Centre for Advanced Imaging. Associate Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Associate Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on three patents. He is also CI on two major ARC Centres: The ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader.​ He is co-inventor on three patents.

Research Impacts

Research

Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, A/Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Publications

View all Publications

Supervision

View all Supervision

Publications

Book Chapter

  • Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2018). Hyperbranched polymers as nanocarriers. Encyclopedia of polymer science and technology. (pp. 1-27) edited by .Hoboken, NJ USA: John Wiley & Sons. doi:10.1002/0471440264.pst159.pub2

  • Fletcher, Nicholas and Thurecht, Kristofer (2016). Molecular imaging utilizing Aptamer-targeted probes. Aptamers Tools for Nanotherapy and Molecular Imaging. (pp. 287-318) edited by Rakesh N. Veedu.Boca Raton, United States: CRC Press.

  • Fletcher, Nicholas and Thurechta, Kristofer (2016). Molecular imaging utilizing aptamer-targeted probes. Aptamers: tools for nanotherapy and molecular imaging. (pp. 287-317) edited by Rakesh N. Veedu.New York, NY, United States: Pan Stanford Publishing. doi:10.4032/9789814669849

  • Barner-Kowollik, Christopher, Blinco, James P., Destarac, Mathias, Thurecht, Kristofer J. and Perrier, Sébastien (2012). Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications. Encyclopedia of radicals in chemistry, biology and materials. (pp. 1895-1929) edited by Chryssostomos Chatgilialoglu and Armido Studer.Chichester, West Sussex, U.K.: John Wiley & Sons. doi:10.1002/9781119953678.rad058

  • Peng, Hui, Thurecht, Kristofer, Hsu, Steven, Blakey, Idriss, Squires, Oliver, Kurniawan, Nyoman, Rose, Stephen and Whittaker, Andrew (2011). Effect of molecular architecture on the performance of (19)F NMR imaging agents. NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules. (pp. 459-472) edited by H. N. Cheng, Tetsuo Asakur and Alan D. English.Washington, DC, United States: American Chemical Society. doi:10.1021/bk-2011-1077.ch028

  • Thurecht, Kristofer James and Villarroya, Silvia (2010). Biocatalytic Polymerization in Exotic Solvents. Biocatalysis in Polymer Chemistry. (pp. 323-348) edited by Katja Loos.Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi:10.1002/9783527632534

Journal Article

Conference Publication

  • Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. In: San Antonio Breast Cancer Symposium, San Antonio, Texas, (). 4-8 December 2018. doi:10.1158/1538-7445.SABCS18-P1-19-02

  • Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Huston, Zachary H., Stewart, Chelsea, Sokolowski, Kamil, Jeet, Varinder, Wissmueller, Sandra, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C. and Russell, Pamela J. (2018). Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1). 19th Asia-Pacific Prostate Cancer Conference, Brisbane Australia, Aug 22-25, 2018. HOBOKEN :WILEY.

  • Offenhauser, Carolin, Carrington, Benjamin, Thurecht, Kris, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Lim, Yi Chieh, Akgul, Seckin, Li, Michelle, Stringer, Brett, Puttick, Simon, Fuchs, Adrian, Picard, Daniel, Ingram, Wendy, Hallahan, Andrew, Moore, Andrew, Johns, Terrance, Gottardo, Nicholas, Remke, Marc, Boyd, Andrew and Day, Bryan (2018). EPHA3 A NOVEL TUMOUR SPECIFIC THERAPEUTIC TARGET FOR MEDULLOBLASTOMA. 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), Denver Co, Jun 30-Jul 03, 2018. CARY :OXFORD UNIV PRESS INC.

  • Lilja, Andrew R., Strong, Campbell W., Bailey, Benjamin J., Thurecht, Kristofer J., Houston, Zachary H., Fletcher, Nicholas L. and McGhee, John B. (2018). Design-led 3D visualization of nanomedicines in virtual reality. 24th ACM Symposium on Virtual Reality Software and Technology (ACM VRST), Tokyo, Japan, Nov 28- Dec 01 2018. New York, NY, United States :Association for Computing Machinery. doi: 10.1145/3281505.3281572

  • Thurecht, Kristofer, Zhou, Yongmei, Fletcher, Nicholas and Houston, Zachary (2018). Development of polymer theranostics to probe the behaviour of nanomaterials in biology. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States :American Chemical Society.

  • Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States :American Chemical Society.

  • Song, Danzi, Cui, Jiwei, Ju, Yi, Sun, Huanli, Thurecht, Kristofer and Caruso, Frank (2017). Harnessing shape and bi-specific antibodies for improved cell-targeting efficiency of poly(ethylene glycol) capsules. 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, San Francisco, CA USA, 2-6 April 2017. Washington, DC USA :American Chemical Society.

  • Carrington, Benjamin, Al-Ejeh, Fares, Lim, Yi Chieh, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Fuchs, Adrian, Thurecht, Kristofer, Stringer, Brett, Boyd, Andrew and Day, Bryan (2016). EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma. 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale Az United States, Nov 17-20, 2016. Oxford United Kingdom :Oxford University Press.

  • Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May 2016. Lausanne, Switzerland :Frontiers Research Foundation. doi: 10.3389/conf.FBIOE.2016.01.02237

  • Sabanathan, Dhanusha, Gurney, Howard, Gillatt, David, Trifunovic, Marko, Magnussen, John, Poursoultan, Pirooz, Shon, Kevin H. O., Walsh, Bradley J., Mazure, Hubert, Velonas, Vicki, Thurecht, Kris, Quach Truong, Wissmueller, Sandra and Campbell, Douglas (2016). MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31 - September 3 2016. United Kingdom :Wiley-Blackwell.

  • Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31-September 3 2016. United Kingdom :Wiley-Blackwell.

  • Bennett, Thomas, Blakey, Idriss, Thurecht, Kristofer and Jack, Kevin (2015). Mapping the lyotropic phase behavior of diblock copolymer iongels. American Chemical Society Meeting, American Chemical Society.

  • Tse, Brian W-C, Fuchs, Adrian V., Huang, Steve S., Heston, Warren D. W., Yeh, Mei-Chun, Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2015). Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer. 2nd Prostate Cancer World Congress (PCWC), Cairns, Australia, 17-21 August 2015.

  • Zhang, Cheng , Wang, Kewei , Peng, Hui , Puttick, Simon , Thurecht, Kris and Whittaker, Andrew (2015). Polymeric MRI agents for disease detection: advances and challenges. 2015 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, United States, 15-20 December 2015.

  • Zhang, Cheng, Wang, Kewei, Thurecht, Kris, Puttick, Simon, Peng, Hui and Whittaker, Andrew (2015). Solution properties of EOGMA-containing macromolecules. 4th Federation of Asian Polymer Societies – International Polymer Congress, Kuala Lumpur, Malaysia, 5-8 October 2015. Weinheim, Germany :

  • Puttick, Simon, Stringer, Brett W., Day, Bryan W., Mardon, Karine, Cowin, Gary J., Fay, Michael, Thurecht, Kristofer J., Whittaker, Andrew K., Boyd, Andrew W. and Rose, Stephen (2014). EphA2 as a diagnostic imaging target in glioblastoma: A PET/MRI study. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States :American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-LB-12

  • Bennett, Thomas, Pei, Kevin, Cheng, Han-Hao, Thurecht, Kristofe J., Jack, Kevin S. and Blakey, Idriss (2014). Extending the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self assembly. Alternative Lithographic Technologies VI, San Jose, United States, 24-27 February 2014. Bellingham, WA, United States :SPIE. doi: 10.1117/12.2046296

  • Fuchs, Adrian V., Pearce, Amanda K., Tse, Brian W. C., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2014). Multimodal hyperbranched polymers for simultaneous imaging and drug delivery for targeted prostate cancer theranostics. ACS 2014: 247th American Chemical Society National Meeting & Exposition, Dallas, TX, USA, 16-20 March, 2014. Washington, DC, United States :American Chemical Society.

  • Dey, Priyanka, Olds, William, Blakey, Idriss, Thurecht, Kristofer J., Izake, Emad L. and Fredericks, Peter M. (2014). SERS-barcoded colloidal gold NP assemblies as imaging agents for use in biodiagnostics. Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry, San Francisco, CA United States, 1-2 February 2014. Bellingham, WA United States :SPIE. doi: 10.1117/12.2037159

  • Whittaker, Andrew K., Thurecht, Kristofer J., Blakey, Idriss and Peng, Hui (2013). Biologically-responsive polymeric F-19 MRI agents. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, 07-11 April 2013. Washington, DC United States :American Chemical Society.

  • Thurecht, Kristofer J., Whittaker, Andrew K., Russell, Pamela J. and Pearce, Amanda (2013). Hyperbranched polymers in theranostics: Development of advanced delivery probes for cancer therapy. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, 07-11 April 2013. Washington, DC United States :American Chemical Society.

  • Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., 22 -26 March 2009. Washington, DC United States :American Chemical Society.

  • Whittaker, Andrew K., Blakey, Idriss, Thurecht, Kristofer J., Squires, Oliver and Varcoe, Kylie (2008). High pressure NMR of polymeric materials. 235th American Chemical Society National Meeting, New Orleans, 6-10 April 2008 . Blacksburg, VA, United States :American Chemical Society.

  • Whittaker, AK, Blakey, I, Thurecht, KJ, Squires, O and Varcoe, K (2008). POLY 624-High pressure NMR of polymeric materials. 235th American-Chemical-Society National Meeting, New Orleans LA, APR 06-10, 2008. WASHINGTON :AMER CHEMICAL SOC.

  • Rintoul, L., Thurecht, K., Chen, L., Goh, K., Hill, D. J. T. and Whittaker, A. K. (2003). Application of Raman Spectroscopic Mapping for the Characterisation of High Performance Polymers. 5th Australian Conference on Vibrational Spectroscopy, Melbourne, 29 Sep - 2 Oct 2003. CSIRO.

  • Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Aspects of the radiation chemistry of poly(chlorotrifluoroethylene). 25th Australasian Polymer Symposium, Armidale, 10-13 February, 2002.

  • Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Radiation chemistry of poly(chlorotrifluoroethylene) for biomedical purposes. Qld Polymer Group Satellite Symposium, Brisbane, 6-8 February, 2002.

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision