The University of Queensland

Evolution of the Mating-Type Locus: The Basidiomycetes

Fraser, J., Hsueh, Y., Findley, K. and Heitman, J. (2007). Evolution of the Mating-Type Locus: The Basidiomycetes. Sex in Fungi: Molecular Determination and Evolutionary Implications. (pp. 19-34) edited by Heitman, J., Kronstad, J., Taylor, J. and Casselton, L.. Washington, DC: ASM Press. doi: 10.1037/11499-002

Sex, MAT, and the Evolution of Fungal Virulence

Fraser, James A. and Heitman, Joseph (2006). Sex, MAT, and the Evolution of Fungal Virulence. Sex, MAT, and the Evolution of Fungal Virulence. (pp. 13-33) edited by Heitman, J, Filler, SG, Edwards, JE and Mitchell, AP. WASHINGTON: AMER SOC MICROBIOLOGY.

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

Wizrah, Maha S. I., Chua, Sheena M. H., Luo, Zhenyao, Manik, Mohammad K., Pan, Mengqi, Whyte, Jessica M. L., Robertson, Avril A. B., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2022). AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. Journal of Biological Chemistry, 298 (10) 102453, 102453. doi: 10.1016/j.jbc.2022.102453

Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence

Fernandes, Kenya E., Fraser, James A. and Carter, Dee A. (2022). Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence. mBio, 13 (2). doi: 10.1128/mbio.00283-22

Identification and characterisation of sPEPs in Cryptococcus neoformans

Erpf, Paige E., Chua, Sheena M.H., Phung, Toan K., Kerr, Edward D., Rothnagel, Joseph A., Schulz, Benjamin L. and Fraser, James A. (2022). Identification and characterisation of sPEPs in Cryptococcus neoformans. Fungal Genetics and Biology, 160 103688, 103688. doi: 10.1016/j.fgb.2022.103688

Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads

Low, Y. S., Garcia, M. D., Lonhienne, T., Fraser, J. A., Schenk, G. and Guddat, L. W. (2021). Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads. Scientific Reports, 11 (1) 21055. doi: 10.1038/s41598-021-00349-9

Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets

Chua, Sheena M. H., Wizrah, Maha S. I., Luo, Zhenyao, Lim, Bryan Y. J., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2021). Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. Journal of Biological Chemistry, 297 (4) 101091. doi: 10.1016/j.jbc.2021.101091

Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens

Chua, Sheena M. H. and Fraser, James A. (2020). Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens. Immunology and Cell Biology, 98 (10), 819-831. doi: 10.1111/imcb.12389

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

Agnew-Francis, Kylie A., Tang, Yu Cheng, Lin, Xin, Low, Yu Shang, Wun, Shun Jie, Kuo, Andy, Elias, S. M. A. Sayeed Ibn, Lonhienne, Thierry G., Condon, Nicholas, Pimentel, Bruna Natalia Alves da Silva, Vergani, Carlos, Smith, Maree T., Fraser, James A., Williams, Craig M. and Guddat, Luke W (2020). Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris. ACS infectious diseases, 6 (11) acsinfecdis.0c00229, 2901-2912. doi: 10.1021/acsinfecdis.0c00229

Structures of fungal and plant acetohydroxyacid synthases

Lonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3

Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans

Spencer, Garrick W.K., Chua, Sheena M.H., Erpf, Paige E., Wizrah, Maha S.I., Dyba, Taylor G., Condon, Nicholas D. and Fraser, James A. (2020). Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans. Fungal Genetics and Biology, 138 103365, 103365. doi: 10.1016/j.fgb.2020.103365

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

Tan, Yuen Ping, Savchenko, Andrei I., Agnew-Francis, Kylie A., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A. and Williams, Craig M. (2020). Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone. Journal of Natural Products, 83 (5) acs.jnatprod.9b01039, 1473-1479. doi: 10.1021/acs.jnatprod.9b01039

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

Tan, Yuen Ping, Agnew‐Francis, Kylie A., Hofmann, Julian, Savchenko, Andrei I., Lafontaine, Scott R., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A., Shellhammer, Thomas H. and Williams, Craig M. (2020). Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents. Chemistry: A European Journal, 26 (7) chem.201904420, 1653-1660. doi: 10.1002/chem.201904420

Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans

So, Yee-Seul, Maeng, Shinae, Yang, Dong-Hoon, Kim, Hyelim, Lee, Kyung-Tae, Yu, Seong-Ryong, Tenor, Jennifer L., Giri, Vinay K., Toffaletti, Dena L., Arras, Samantha, Fraser, James A., Perfect, John R. and Bahn, Yong-Sun (2019). Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans. mSphere, 4 (6) e00785, e00785-19. doi: 10.1128/mSphere.00785-19

amdS as a dominant recyclable marker in Cryptococcus neoformans

Erpf, Paige E., Stephenson, Christina J. and Fraser, James A. (2019). amdS as a dominant recyclable marker in Cryptococcus neoformans. Fungal Genetics and Biology, 131 103241, 103241. doi: 10.1016/j.fgb.2019.103241

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B. and Schroder, Kate (2019). MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition. Nature Chemical Biology, 15 (6), 556-559. doi: 10.1038/s41589-019-0277-7

Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection

Chitty, Jessica L., Edwards, David J., Robertson, Avril A. B., Butler, Mark S., Duley, John A., Cooper, Matthew A. and Fraser, James A. (2019). Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection. Mycopathologia, 184 (2), 273-281. doi: 10.1007/s11046-018-0315-0

Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections

Garcia, Mario D., Chua, Sheena M. H., Low, Yu-Shang, Lee, Yu-Ting, Agnew-Francis, Kylie, Wang, Jian-Guo, Nouwens, Amanda, Lonhienne, Thierry, Williams, Craig M., Fraser, James A. and Guddat, Luke W. (2018). Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proceedings of the National Academy of Sciences of the United States of America, 115 (41), E9649-E9658. doi: 10.1073/pnas.1809422115

Cell Wall and Whole Cell Proteomes Define Flocculation and Fermentation Behavior of Yeast

Kerr, Edward, McDiarmid, Duin, Fraser, James and Schulz, Benjamin (2018). Cell Wall and Whole Cell Proteomes Define Flocculation and Fermentation Behavior of Yeast. Fermentation, 4 (3) 80, 80. doi: 10.3390/fermentation4030080

Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles

Kummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A. and Robertson, Avril A.B. (2018). Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. Bioorganic and Medicinal Chemistry, 26 (20), 5408-5419. doi: 10.1016/j.bmc.2018.09.004

Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

Hommel, Benjamin, Mukaremera, Liliane, Cordero, Radames J. B., Coelho, Carolina, Desjardins, Christopher A., Sturny-Leclère, Aude, Janbon, Guilhem, Perfect, John R., Fraser, James A., Casadevall, Arturo, Cuomo, Christina A., Dromer, Françoise, Nielsen, Kirsten and Alanio, Alexandre (2018). Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators. PLoS Pathogens, 14 (5) e1006982, e1006982. doi: 10.1371/journal.ppat.1006982

The beer and biofuels laboratory: a report on implementing and supporting a large, interdisciplinary, yeast-focused course-based undergraduate research experience

Pedwell, Rhianna K., Fraser, James A., Wang, Jack T. H., Clegg, Jack K., Chartres, Jy D. and Rowland, Susan L. (2018). The beer and biofuels laboratory: a report on implementing and supporting a large, interdisciplinary, yeast-focused course-based undergraduate research experience. Biochemistry and Molecular Biology Education , 46 (3), 213-222. doi: 10.1002/bmb.21111

The long history of the diverse roles of short ORFs: sPEPs in fungi

Erpf, Paige E. and Fraser, James A. (2018). The long history of the diverse roles of short ORFs: sPEPs in fungi. Proteomics, 18 (10) 1700219, e1700219. doi: 10.1002/pmic.201700219

High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism

Lonhienne, Thierry, Garcia, Mario D., Noble, Chris, Harmer, Jeffrey, Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism. Chemistryselect, 2 (36), 11981-11988. doi: 10.1002/slct.201702128

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic

Arras, Samantha D. M., Ormerod, Kate L., Erpf, Paige E., Espinosa, Monica I., Carpenter, Alex C., Blundell, Ross D., Stowasser, Samantha R., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic. Scientific Reports, 7 (1) 17918, 1-14. doi: 10.1038/s41598-017-18106-2

Antimicrobial octapeptin C4 analogues active against Cryptococcus species

Chitty, Jessica L., Butler, Mark S., Suboh, Azzah, Edwards, David J., Cooper, Matthew A., Fraser, James A. and Robertson, Avril A. B. (2017). Antimicrobial octapeptin C4 analogues active against Cryptococcus species. Antimicrobial agents and chemotherapy, 62 (2) e00986-17, 1-10. doi: 10.1128/AAC.00986-17

A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome

Upadhya, Rajendra, Lam, Woei C., Maybruck, Brian T., Donlin, Maureen J., Chang, Andrew L., Kayode, Sarah, Ormerod, Kate L., Fraser, James A., Doering, Tamara L. and Lodge, Jennifer K. (2017). A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. Fungal Genetics and Biology : FG & B, 108, 13-25. doi: 10.1016/j.fgb.2017.08.008

Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design

Chitty, Jessica L., Blake, Kirsten L., Blundell, Ross D., Koh, Y. Q. Andre E., Thompson, Merinda, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kappler, Ulrike, Williams, Simon J., Kobe, Bostjan and Fraser, James A. (2017). Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. Journal of Biological Chemistry, 292 (28), 11829-11839. doi: 10.1074/jbc.M117.787994

Importance of resolving fungal nomenclature: the case of multiple pathogenic species in the Cryptococcus genus

Hagen, Ferry, Lumbsch, H. Thorsten, Arsenijevic, Valentina Arsic, Badali, Hamid, Bertout, Sebastien, Billmyre, R. Blake, Rosa Bragulat, M., Javier Cabanes, F., Carbia, Mauricio, Chakrabarti, Arunaloke, Chaturvedi, Sudha, Chaturvedi, Vishnu, Chen, Min, Chowdhary, Anuradha, Colom, Maria-Francisca, Cornely, Oliver A., Crous, Pedro W., Cuetara, Maria S., Diaz, Mara R., Espinel-Ingroff, Ana, Fakhim, Hamed, Falk, Rama, Fang, Wenjie, Herkert, Patricia F., Ferrer Rodriguez, Consuelo, Fraser, James A., Gene, Josepa, Guarro, Josep, Idnurm, Alexander ... Boekhoutiii, Teun (2017). Importance of resolving fungal nomenclature: the case of multiple pathogenic species in the Cryptococcus genus. Msphere, 2 (4) e00238-17. doi: 10.1128/mSphere.00238-17

Purine acquisition and synthesis by human fungal pathogens

Chitty, Jessica L. and Fraser, James A. (2017). Purine acquisition and synthesis by human fungal pathogens. Microorganisms, 5 (2) 33, 33.1-33.16. doi: 10.3390/microorganisms5020033

Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans

Arras, Samantha D. M., Chitty, Jessica L., Wizrah, Maha S. I., Erpf, Paige E., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans. Scientific Reports, 7 (1) 46567, 46567.1-46567.14. doi: 10.1038/srep46567

GMP synthase is required for virulence factor production and infection by cryptococcus neoformans

Chitty, Jessica L., Tatzenko, Tayla L. , Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2017). GMP synthase is required for virulence factor production and infection by cryptococcus neoformans. Journal of Biological Chemistry, 292 (7), 3049-3059. doi: 10.1074/jbc.M116.767533

The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements

Lonhienne, Thierry, Garcia, Mario D., Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements. PLoS One, 12 (2) e0171443, e0171443.1-e0171443.13. doi: 10.1371/journal.pone.0171443

Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]

Borneman, A. R., Forgan, A.H., Kolouchova, R., Fraser, J. A. and Schmidt, S.A. (2017). Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]. G3: Genes, Genomes, Genetics, 7 (1), 319-319. doi: 10.1534/g3.116.036038

Targeted genome editing via CRISPR in the pathogen Cryptococcus neoformans

Arras, Samantha D. M., Chua, Sheena M. H., Wizrah, Maha S. I., Faint, Joshua A., Yap, Amy S. and Fraser, James A. (2016). Targeted genome editing via CRISPR in the pathogen Cryptococcus neoformans. PloS One, 11 (10) e0164322, e0164322. doi: 10.1371/journal.pone.0164322

Chemical inhibitors of non-homologous end joining increase targeted construct integration in Cryptococcus neoformans

Arras, Samantha D. M. and Fraser, James A. (2016). Chemical inhibitors of non-homologous end joining increase targeted construct integration in Cryptococcus neoformans. PLoS One, 11 (9) e0163049, e0163049. doi: 10.1371/journal.pone.0163049

Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans

Blundell, Ross D., Williams, Simon J., Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Ericsson, Daniel J., Tibrewal, Nidhi, Rohr, Jurgen, Koh, Y. Q. Andre, Kappler, Ulrike, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kobe, Bostjan and Fraser, James A. (2016). Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans. ACS Infectious Diseases, 2 (9), 651-663. doi: 10.1021/acsinfecdis.6b00121

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F

Beattie, Karren D., Ellwood, Nicola, Kumar, Rohitesh, Yang, Xinzhou, Healy, Peter C., Choomuenwai, Vanida, Quinn, Ronald J., Elliott, Alysha G., Huang, Johnny X., Chitty, Jessica L., Fraser, James A., Cooper, Matthew A. and Davis, Rohan A. (2016). Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F. Phytochemistry, 124, 79-85. doi: 10.1016/j.phytochem.2015.12.014

Whole genome comparison reveals high levels of inbreeding and strain redundancy across the spectrum of commercial wine strains of Saccharomyces cerevisiae

Borneman, Anthony R., Forgan, Angus H., Kolouchova, Radka, Fraser, James A. and Schmidt, Simon A. (2016). Whole genome comparison reveals high levels of inbreeding and strain redundancy across the spectrum of commercial wine strains of Saccharomyces cerevisiae. G3: Genes, Genomes, Genetics, 6 (4), 957-971. doi: 10.1534/g3.115.025692

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase. Angewandte Chemie, 128 (13), 4319-4323. doi: 10.1002/ange.201511985

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie - International Edition, 55 (13), 4247-4251. doi: 10.1002/anie.201511985

Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

Gerstein, Aleeza C., Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L., Fraser, James A, Berman, Judith and Nielsen, Kirsten (2015). Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation. mBio, 6 (5) e01340-15, e01340-15. doi: 10.1128/mBio.01340-15

Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients

Ormerod, Kate L., George, Narelle M., Fraser, James A., Wainwright, Claire and Hugenholtz, Philip (2015). Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients. PeerJ, 3 (9) e1223, e1223.1-e1223.27. doi: 10.7717/peerj.1223

Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum

Rees, Karlee A., Bermudez, Cindy, Edwards, David J., Elliott, Alysha G., Ripen, Jovita E., Seta, Cynthia, Huang, Johnny X., Cooper, Matthew A., Fraser, James A., Yeo, Tiong C. and Butler, Mark S. (2015). Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum. Journal of Natural Products, 78 (8), 2141-2144. doi: 10.1021/acs.jnatprod.5b00410

Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane

Taniguti, Lucas M., Schaker, Patricia D. C., Benevenuto, Juliana, Peters, Leila P., Carvalho, Giselle, Palhares, Alessandra, Quecine, Maria C., Nunes, Filipe R. S., Kmit, Maria C. P., Wai, Alvan, Hausner, Georg, Aitken, Karen S., Berkman, Paul J., Fraser, James A., Moolhuijzen, Paula M., Coutinho, Luiz L., Creste, Silvana, Vieira, Maria L. C., Kitajima, João P. and Monteiro-Vitorello, Claudia B. (2015). Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane. PLoS One, 10 (6) e0129318, e0129318. doi: 10.1371/journal.pone.0129318

Rethinking the targets for antifungal development

Chitty, Jessica L. and Fraser, James A. (2015). Rethinking the targets for antifungal development. Microbiology Australia, 36 (2), 88-89. doi: 10.1071/MA15028

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.

Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Schulz, Benjamin L. and Fraser, James A. (2015). A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.. PLoS One, 10 (4) e0122916, e0122916-e0122916. doi: 10.1371/journal.pone.0122916

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

Kwon-Chung, Kyung J., Fraser, James A., Doering, Tamara L., Wang, Zhuo A., Janbon, Guilhem, Idnurm, Alexander and Bahn, Yong-Sun (2014). Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis. Cold Spring Harbor Perspectives in Medicine, 4 (7), a019760.1-a019760.27. doi: 10.1101/cshperspect.a019760

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

Janbon, Guilhem, Ormerod, Kate L., Paulet, Damien, Byrnes III, Edmond J., Yadav, Vikas, Chatterjee, Gautam, Mullapudi, Nandita, Hon, Chung-Chau, Billmyre, R. Blake, Brunel, François, Bahn, Yong-Sun, Chen, Weidong, Chen, Yuan, Chow, Eve W. L., Coppée, Jean-Yves, Floyd-Averette, Anna, Gaillardin, Claude, Gerik, Kimberly J., Goldberg, Jonathan, Gonzalez-Hilarion, Sara, Gujja, Sharvari, Hamlin, Joyce L., Hsueh, Yen-Ping, Ianiri, Giuseppe, Jones, Steven, Kodira, Chinnappa D., Kozubowski, Lukasz, Lam, Woei, Marra, Marco ... Dietrich, Fred S. (2014). Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genetics, 10 (4) e1004261, e1004261.1-e1004261.26. doi: 10.1371/journal.pgen.1004261

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA

Hunter, Cameron C., Siebert, Kendra S., Downes, Damien J., Wong, Koon Ho, Kreutzberger, Sara D., Fraser, James A., Clarke, David F., Hynes, Michael J., Davis, Meryl A. and Todd, Richard B. (2014). Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA. Eukaryotic Cell, 13 (4), 527-538. doi: 10.1128/EC.00040-14

Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans

Ormerod, Kate L. and Fraser, James A. (2013). Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans. PLoS Pathogens, 9 (12) e1003764, 1-4. doi: 10.1371/journal.ppat.1003764

Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans

Blundell, Ross D., Williams, Simon J., Morrow, Carl A., Ericsson, Daniel J., Kobe, Bostjan and Fraser, James A. (2013). Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (Pt. 9), 1033-1036. doi: 10.1107/S1744309113021921

Secondary metabolites of the sponge-derived fungus Acremonium persicinum

Suciati, Fraser, James A., Lambert, Lynette K., Pierens, Gregory K., Bernhardt, Paul V. and Garson, Mary J. (2013). Secondary metabolites of the sponge-derived fungus Acremonium persicinum. Journal of Natural Products, 76 (8), 1432-1440. doi: 10.1021/np4002114

Nitrogen regulation of virulence in clinically prevalent fungal pathogens

Lee, I. Russel, Morrow, Carl A. and Fraser, James A. (2013). Nitrogen regulation of virulence in clinically prevalent fungal pathogens. FEMS Microbiology Letters, 345 (2), 77-84. doi: 10.1111/1574-6968.12181

Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?

Morrow, Carl A. and Fraser, James A. (2013). Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?. MBio, 4 (4) e00408-13, e00408-13.1-e00408-13.3. doi: 10.1128/mBio.00408-13

Reactive oxygen species homeostasis and virulence of the fungal pathogen Cryptococcus neoformans requires an intact proline catabolism pathway

Lee, I. Russel, Lui, Edmund Y. L., Chow, Eve W. L., Arras, Samantha D. M., Morrow, Carl A. and Fraser, James A. (2013). Reactive oxygen species homeostasis and virulence of the fungal pathogen Cryptococcus neoformans requires an intact proline catabolism pathway. Genetics, 194 (2), 421-U199. doi: 10.1534/genetics.113.150326

Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformans

Lee, I. Russel, Yang, Liting, Sebetso, Gaseene, Allen, Rebecca, Doan, Thi H. N., Blundell, Ross, Lui, Edmund Y. L., Morrow, Carl A. and Fraser, James A. (2013). Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformans. PLoS ONE, 8 (5) e64292, e64292.1-e64292.13. doi: 10.1371/journal.pone.0064292

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

Ormerod, Kate L., Morrow, Carl A., Chow, Eve W. L., Lee, I. Russel, Arras, Samantha D. M., Schirra, Horst Joachim, Cox, Gary M., Fries, Bettina C. and Fraser, James A. (2013). Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence. G3: Genes, Genomes, Genetics, 3 (4), 675-686. doi: 10.1534/g3.113.005660

Ploidy variation as an adaptive mechanism in human pathogenic fungi

Morrow, Carl A. and Fraser, James A. (2013). Ploidy variation as an adaptive mechanism in human pathogenic fungi. Seminars in Cell and Developmental Biology, 24 (4), 339-346. doi: 10.1016/j.semcdb.2013.01.008

Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase

Lee, Yu-Ting, Cui, Chang-Jun, Chow, Eve W. L., Pue, Nason, Lonhienne, Thierry, Wang, Jian-Guo, Fraser, James A. and Guddat, Luke W. (2013). Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. Journal of Medicinal Chemistry, 56 (1), 210-219. doi: 10.1021/jm301501k

De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans

Morrow, Carl A., Valkov, Eugene, Stamp, Anna, Chow, Eve W. L., Lee, I. Russel, Wronski, Ania, Williams, Simon J., Hill, Justine M., Djordjevic, Julianne T., Kappler, Ulrke, Kobe, Bostjan and Fraser, James A. (2012). De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans. PLoS Pathogens, 8 (10) e1002957, e1002957. doi: 10.1371/journal.ppat.1002957

A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence

Morrow, Carl A., Lee, I. Russell, Chow, Eve W. L., Ormerod, Kate L., Goldinger, Anita, Byrnes III, Edmond J., Nielsen, Kirsten, Heitman, Joseph, Schirra, Horst Joachim and Fraser, James A. (2012). A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. mBio, 3 (2) e00310-11, e00310.1-e00310.11. doi: 10.1128/mBio.00310-11

Characterization of an Nmr homolog that modulates gata factor-mediated nitrogen metabolite repression in Cryptococcus neoformans

Lee, I. Russel, Lim, Jonathan W. C., Ormerod, Kate L., Morrow, Carl A. and Fraser, James A. (2012). Characterization of an Nmr homolog that modulates gata factor-mediated nitrogen metabolite repression in Cryptococcus neoformans. PLoS One, 7 (3) e32585, e32585.1-e32585.15. doi: 10.1371/journal.pone.0032585

Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus amylolentus and the Evolution of MAT in the Cryptococcus Species Complex

Findley, Keisha, Sun, Sheng, Fraser, James A., Hsueh, Yen-Ping, Averette, Anna Floyd, Li, Wenjun, Dietrich, Fred S. and Heitman, Joseph (2012). Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus amylolentus and the Evolution of MAT in the Cryptococcus Species Complex. PLoS Genetics, 8 (2) e1002528, e1002528-1-e1002528-19. doi: 10.1371/journal.pgen.1002528

Microevolution of Cryptococcus neoformans driven by massive tandem gene amplification

Chow, Eve W. L., Morrow, Carl A., Djordjevic, Julianne T., Wood, Ian A. and Fraser, James A. (2012). Microevolution of Cryptococcus neoformans driven by massive tandem gene amplification. Molecular Biology and Evolution, 29 (8), 1987-2000. doi: 10.1093/molbev/mss066

A diverse population of Cryptococcus gattii molecular type VGIII in Southern Californian HIV/AIDS patients

Byrnes, Edmond J., Li, Wenjun, Ren, Ping, Lewit, Yonathan, Voelz, Kerstin, Fraser, James A., Dietrich, Fred S., May, Robin C., Chatuverdi, Sudha, Chatuverdi, Vishnu and Heitman, Joseph (2011). A diverse population of Cryptococcus gattii molecular type VGIII in Southern Californian HIV/AIDS patients. PLoS Pathogens, 7 (9) e1002205, 134-1. doi: 10.1371/journal.ppat.1002205

Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus neoformans

Lee, I. Russel, Chow, Eve W. L., Morrow, Carl A., Djordjevic, Julianne T. and Fraser, James A. (2011). Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus neoformans. Genetics, 188 (2), 309-323. doi: 10.1534/genetics.111.128538

Genome Variation in Cryptococcus gattii, an Emerging Pathogen of Immunocompetent Hosts

D'Souza, C.A., Kronstad, J.W., Taylor, G., Warrne, R., Yuen, M., Hu, G., Jung, W.H., Sham, A., Kidd, S.E., Tangen, K., Lee, N., Zeilmaker, T., Sawkins, J., McVicker, G., Shah, S., Gnerre, S., Griggs, A., Zeng, Q., Bartlett, K., Li, W., Wang, X., Heitman, J., Stajich, J.E., Fraser, J.A., Meyer, W., Carter, D., Schein, J., Krzywinski, M., Kwon-Chung, K.J. ... Cuomo, C.A. (2011). Genome Variation in Cryptococcus gattii, an Emerging Pathogen of Immunocompetent Hosts. mBio, 2 (1) e00342-10, e00342-1-e00342-10. doi: 10.1128/mBio.00342-10

Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus

Morrow, CA, Stamp, A, Valkov, E, Kobe, B and Fraser, JA (2010). Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66 (9), 1104-1107. doi: 10.1107/S1744309110031659

Sexual reproduction and dimorphism in the pathogenic basidiomycetes

Morrow, Carl A. and Fraser, James A. (2009). Sexual reproduction and dimorphism in the pathogenic basidiomycetes. FEMS Yeast Research, 9 (2), 161-177. doi: 10.1111/j.1567-1364.2008.00475.x

Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans

Hsueh, Yen-Ping, Fraser, James A. and Heitman, Joseph (2008). Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans. Eukaryotic Cell, 7 (10), 1847-1855. doi: 10.1128/EC.00271-08

First contemporary case of human infection with Cryptococcus gattii in Puget Sound: Evidence for spread of the Vancouver Island outbreak

Upton, A., Fraser, J., Kidd, S., Bretz, C., Bartlett, K., Heitman, J. and Marr, K. (2007). First contemporary case of human infection with Cryptococcus gattii in Puget Sound: Evidence for spread of the Vancouver Island outbreak. Journal of Clinical Microbiology, 45 (9), 3086-3088. doi: 10.1128/JCM.00593-07

Evolution of the mating type locus: Insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii

Fraser, James A., Stajich, Jason E., Tarcha, Eric J., Cole, Garry T., Inglis, Diane O., Sil, Anita and Heitman, Joseph (2007). Evolution of the mating type locus: Insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii. Eukaryotic Cell, 6 (4), 622-629. doi: 10.1128/EC.00018-07

Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale

Fraser, J. A., Lim, S. M. C., Diezmann, S., Wenink, E. C., Arndt, C. G., Cox, G. M., Dietrich, F. S. and Heitman, J. (2006). Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. Fems Yeast Research, 6 (4), 620-624. doi: 10.1111/j.1567-1364.2006.00075.x

Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment

Kavanaugh, L. A., Fraser, J. A. and Dietrich, F. S. (2006). Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment. Molecular Biology And Evolution, 23 (10), 1879-1890. doi: 10.1093/molbev/msl070

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans

Loftus, B. J., Fung, E., Roncaglia, P., Rowley, D., Amedeo, P., Bruno, D., Vamathevan, J., Miranda, M., Anderson, I. J., Fraser, J. A., Allen, J. E., Bosdet, I. E., Brent, M. R., Chiu, R., Doering, T. L., Dontin, M. J., D'Souza, C. A., Fox, D. S., Grinberg, V., Fu, J. M., Fukushima, M., Haas, B. J., Huang, J. C., Janbon, G., Jones, S. J. M., Koo, H. L., Krzywinski, M. I., Kwon-Chung, J. K., Lengeler, K. B. and Maiti, R. (2005). The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science, 307 (5713), 1321-1324. doi: 10.1126/science.1103773

Chromosomal sex-determining regions in animals, plants and fungi

Fraser, J. A. and Heitman, J. (2005). Chromosomal sex-determining regions in animals, plants and fungi. Current Opinion In Genetics & Development, 15 (6), 645-651. doi: 10.1016/j.gde.2005.09.002

Chromosomal translocation and segmental duplication in Cryptococcus neoformans

Fraser, J. A., Huang, J. C., Pukkila-Worley, R., Alspaugh, J. A., Mitchell, T. G. and Heitman, J. (2005). Chromosomal translocation and segmental duplication in Cryptococcus neoformans. Eukaryotic Cell, 4 (2), 401-406. doi: 10.1128/EC.4.2.401-406.2005

Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity

Campbell, L. T., Fraser, J. A., Nichols, C. B., Dietrich, F. S., Dietrich and Heitman, J. (2005). Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. Eukaryotic Cell, 4 (8), 1410-1419. doi: 10.1128/EC.4.8.1410-1419.2005

Deciphering the model pathogenic fungus Cryptococcus neoformans

Idnurm, A., Bahn, Y. S., Nielsen, K., Lin, X. R., Fraser, J. A. and Heitman, J. (2005). Deciphering the model pathogenic fungus Cryptococcus neoformans. Nature Reviews Microbiology, 3 (10), 753-764. doi: 10.1038/nrmicro1245

Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export

Todd, R. B., Fraser, J. A., Wong, K. H., Davis, M. A. and Hynes, M. J. (2005). Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export. Eukaryotic Cell, 4 (10), 1646-1653. doi: 10.1128/EC.4.10.1646-1653.2005

Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak

Fraser, J. A., Giles, S. S., Wenink, E. C., Geunes-Boyer, S. G., Wright, J. R., Diezmann, S., Allen, A., Stajich, J. E., Dietrich, F. S., Perfect, J. R. and Heitman, J. (2005). Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature, 437 (7063), 1360-1364. doi: 10.1038/nature04220

Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms

Fraser, James A., Diezmann, Stephanie, Subaran, Ryan L., Allen, Andria, Lengeler, Klaus B., Dietrich, Fred S. and Heitman, Joseph (2004). Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. Plos Biology, 2 (12), 2243-2255. doi: 10.1371/journal.pbio.0020384

Evolution of fungal sex chromosomes

Fraser, J. A. and Heitman, J. (2004). Evolution of fungal sex chromosomes. Molecular Microbiology, 51 (2), 299-306. doi: 10.1046/j.1365-2958.2003.03874.x

PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans

Nichols, C. B., Fraser, J. A. and Heitman, J. (2004). PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans. Molecular Biology of The Cell, 15 (10), 4476-4489. doi: 10.1091/mbc.E04-05-0370

Fungal mating-type loci

Fraser, J. A. and Heitman, J. (2003). Fungal mating-type loci. Current Biology, 13 (20), R792-R795. doi: 10.1016/j.cub.2003.09.046

Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada

Fraser, James A., Subaran, Ryan L., Nichols, Connie B. and Heitman, Joseph (2003). Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada. Eukaryotic Cell, 2 (5), 1036-1045. doi: 10.1128/EC.2.5.1036-1045.2003

Mating-type locus of Cryptococcus neoformans: A step in the evolution of sex chromosomes

Lengeler, Klaus B., Fox, Deborah S., Fraser, James A., Allen, Andria, Forrester, Keri, Dietrich, Fred S. and Heitman, Joseph (2002). Mating-type locus of Cryptococcus neoformans: A step in the evolution of sex chromosomes. Eukaryotic Cell, 1 (5), 704-718. doi: 10.1128/EC.1.5.704-718.2002

A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance

Fraser, J. A., Davis, M. A. and Hynes, M. J. (2002). A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Applied And Environmental Microbiology, 68 (6), 2802-2808. doi: 10.1128/AEM.68.6.2802-2808.2002

Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans

Monahan, B. J., Fraser, J. A., Hynes, M. J. and Davis, M. A. (2002). Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans. Eukaryotic Cell, 1 (1), 85-94. doi: 10.1128/EC.1.1.85-94.2002

The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans

Fraser, J. A., Davis, M. A. and Hynes, M. J. (2002). The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans. Fungal Genetics And Biology, 35 (2), 135-146. doi: 10.1006/fgbi.2001.1307

The formamidase gene of Aspergillus nidulans: Regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene

Fraser, J. A., Davis, M. A. and Hynes, M. J. (2001). The formamidase gene of Aspergillus nidulans: Regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene. Genetics, 157 (1), 119-131.

Home visiting intervention for vulnerable families with newborns: Follow-up results of a randomized controlled trial

Fraser, J. A., Armstrong, K. L., Morris, J. P. and Dadds, M. R. (2000). Home visiting intervention for vulnerable families with newborns: Follow-up results of a randomized controlled trial. Child Abuse and Neglect, 24 (11), 1399-1429. doi: 10.1016/S0145-2134(00)00193-9

Enhancing the complementation process in Cryptococcus neoformans

Arras, S. D. M. and Fraser, J. A. (2014). Enhancing the complementation process in Cryptococcus neoformans. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

Purine biosynthetic enzymes as antifungal drug targets

Blundell, R. B., Arras, S. D. M., Williams, S. J. and Fraser, J. A. (2014). Purine biosynthetic enzymes as antifungal drug targets. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing

Ormerod, K. L., Byrnes, E. J., III, Wood, I. A., Lodge, J. K., Heitman, J. and Fraser, J. A. (2014). The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

Secondary metabolites from saltwater culture of the sponge-derived fungus Acremonium persicinum

Suciati, Fraser, James A. and Garson, Mary J. (2011). Secondary metabolites from saltwater culture of the sponge-derived fungus Acremonium persicinum. International Symposium on the Chemistry of Natural Products (27th, ISCNP, 2011) and the 7th International Conference on Biodiversity (7th, ICOB, 2011), South Bank, QLD, Australia, 10-15 July 2011.

The Cryptococcus neoformans mating-type locus: evolutionary insights from related species

Fraser, J (2006). The Cryptococcus neoformans mating-type locus: evolutionary insights from related species. 8th International Mycological Conference, Cairns, August, 2006.