The University of Queensland

Metal-peptide complexes to study neurodegenerative diseases

Mital, Mariusz, Sęk, Jakub P. and Ziora, Zyta M. (2020). Metal-peptide complexes to study neurodegenerative diseases. Peptide synthesis: methods and protocols. (pp. 323-336) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_22

Peptidomimetic synthesis: drug discovery for Alzheimer's disease

Hamada, Yoshio and Ziora, Zyta M. (2020). Peptidomimetic synthesis: drug discovery for Alzheimer's disease. Peptide synthesis: methods and protocols. (pp. 215-223) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_14

Solid-phase synthesis of octapeptin lipopeptides

Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Solid-phase synthesis of octapeptin lipopeptides. Peptide synthesis: methods and protocols. (pp. 199-213) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_13

Medicinal chemistry of a-hydroxy-b-amino acids

Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2011). Medicinal chemistry of a-hydroxy-b-amino acids. Amino Acids, Peptides and Proteins in Organic Chemistry: Volume 4 - Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. (pp. 189-234) edited by Andrew B. Hughes. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527631827.ch6

β-Caryophyllene-Loaded Microemulsion-Based Topical Hydrogel: A Promising Carrier to Enhance the Analgesic and Anti-Inflammatory Outcomes

Alharthi, Sitah, Ziora, Zyta Maria, Mustafa, Gulam, Chaubey, Pramila, El Kirdasy, Ahmed Farag and Alotaibi, Ghallab (2023). β-Caryophyllene-Loaded Microemulsion-Based Topical Hydrogel: A Promising Carrier to Enhance the Analgesic and Anti-Inflammatory Outcomes. Gels, 9 (8) 634, 634. doi: 10.3390/gels9080634

A supramolecular self-assembly of peptide-derived compounds via 1,5-disubstituted tetrazole-based supramolecular synthons: An experimental and computational study

Bojarska, Joanna, Breza, Martin, Remko, Milan, Yuan, Ye, Ziora, Zyta M., Chai, Tsun-Thai, Madura, Izabela D., Kaczmarek, Krzysztof, Blaskovich, Mark A.T. and Wolf, Wojciech M. (2023). A supramolecular self-assembly of peptide-derived compounds via 1,5-disubstituted tetrazole-based supramolecular synthons: An experimental and computational study. Journal of Molecular Structure, 1288 135732, 135732. doi: 10.1016/j.molstruc.2023.135732

Photocatalytic Degradation of Methylparaben Using Green Nanosilver Supported on Reduced Graphene Oxide

Khan, Sadaf Aiman, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A. T. (2023). Photocatalytic Degradation of Methylparaben Using Green Nanosilver Supported on Reduced Graphene Oxide. Industrial & Engineering Chemistry Research, 62 (17), 6646-6659. doi: 10.1021/acs.iecr.3c00146

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114

Bioactive peptide discovery from edible insects for potential applications in human health and agriculture

Quah, Yixian, Tong, Shi-Ruo, Bojarska, Joanna, Giller, Katrin, Tan, Sheri-Ann, Ziora, Zyta Maria, Esatbeyoglu, Tuba and Chai, Tsun-Thai (2023). Bioactive peptide discovery from edible insects for potential applications in human health and agriculture. Molecules, 28 (3) 1233, 1-23. doi: 10.3390/molecules28031233

Antioxidant and antibacterial activity of four tannins isolated from different sources and their effect on the shelf-life extension of vacuum-packed minced meat

Nguyen, Chau Ngoc Minh, Nirmal, Nilesh Prakash, Sultanbawa, Yasmina and Ziora, Zyta M. (2023). Antioxidant and antibacterial activity of four tannins isolated from different sources and their effect on the shelf-life extension of vacuum-packed minced meat. Foods, 12 (2) 354, 1-16. doi: 10.3390/foods12020354

Leveraging the potential of silver nanoparticles-based materials towards sustainable water treatment

Khan, Sadaf Aiman, Jain, Marut, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A. T., Shetti, Nagaraj P. and Aminabhavi, Tejraj M. (2022). Leveraging the potential of silver nanoparticles-based materials towards sustainable water treatment. Journal of Environmental Management, 319 115675, 115675. doi: 10.1016/j.jenvman.2022.115675

Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea

Wahid, Muqeet, Saqib, Fatima, Qamar, Muhammad and Ziora, Zyta M. (2022). Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea. Journal of Ethnopharmacology, 295 115314, 115314. doi: 10.1016/j.jep.2022.115314

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

New Advances in Short Peptides: Looking Forward

Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Feehan, Jack, Kaczmarek, Krzysztof, Matsoukas, John M., Paredes Lopez, Octavio, Saviano, Michele, Skwarczynski, Mariusz, Smith-Carpenter, Jillian, Venanzi, Mariano, Wolf, Wojciech M., Zielenkiewicz, Piotr and Ziora, Zyta M. (2022). New Advances in Short Peptides: Looking Forward. Molecules, 27 (11) 3635, 3635. doi: 10.3390/molecules27113635

Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking

Somashekar, M. N., Chetana, P. R., Chethan, B. S., Rajegowda, H. R., Cooper, M. A., Ziora, Z. M., Lokanath, N. K., Ganapathy, P.S. Sujan and Srinatha, B. S. (2022). Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking. Journal of Molecular Structure, 1255 132429, 132429. doi: 10.1016/j.molstruc.2022.132429

Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides

Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986

Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies

Jain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030

Syzygium cumini (L.) Skeels extracts; in vivo anti-nociceptive, anti-inflammatory, acute and subacute toxicity assessment

Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Ali, Sajed, Nazir, Yasir, Murtaza, Shahid, Abbas, Malik Waseem and Ziora, Zyta M. (2022). Syzygium cumini (L.) Skeels extracts; in vivo anti-nociceptive, anti-inflammatory, acute and subacute toxicity assessment. Journal of Ethnopharmacology, 287 114919, 114919. doi: 10.1016/j.jep.2021.114919

Antiinflammatory and anticancer properties of Grewia asiatica crude extracts and fractions: a bioassay-guided approach

Qamar, Muhammad, Akhtar, Saeed, Barnard, Ross T., Sestili, Piero, Ziora, Zyta M., Lazarte, Claudia E. and Ismail, Tariq (2022). Antiinflammatory and anticancer properties of Grewia asiatica crude extracts and fractions: a bioassay-guided approach. BioMed Research International, 2022 2277417, 1-14. doi: 10.1155/2022/2277417

Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents

Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412

Insights into recent advances of chitosan-based adsorbents for sustainable removal of heavy metals and anions

Omer, Ahmed M., Dey, Rana, Eltaweil, Abdelazeem S., Abd El-Monaem, Eman M. and Ziora, Zyta M. (2022). Insights into recent advances of chitosan-based adsorbents for sustainable removal of heavy metals and anions. Arabian Journal of Chemistry, 15 (2) 103543, 103543. doi: 10.1016/j.arabjc.2021.103543

Phytochemical profile, biological properties, and food applications of the medicinal plant Syzygium cumini

Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Abbas, Malik Waseem, Mubarak, Mohammad S., Yuan, Ye, Barnard, Ross T., Ziora, Zyta M. and Esatbeyoglu, Tuba (2022). Phytochemical profile, biological properties, and food applications of the medicinal plant Syzygium cumini. Foods, 11 (3) 378, 378. doi: 10.3390/foods11030378

The chemical composition and health-promoting effects of the Grewia species—a systematic review and meta-analysis

Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Barnard, Ross T., Esatbeyoglu, Tuba and Ziora, Zyta M. (2021). The chemical composition and health-promoting effects of the Grewia species—a systematic review and meta-analysis. Nutrients, 13 (12) 4565, 4565. doi: 10.3390/nu13124565

Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition

Alharthi, Sitah, Ziora, Zyta Maria and Moyle, Peter Michael (2021). Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition. Bioorganic and Medicinal Chemistry, 52 116527, 116527. doi: 10.1016/j.bmc.2021.116527

Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment

Jain, Marut, Khan, Sadaf Aiman, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment. Science of The Total Environment, 793 148583, 1-19. doi: 10.1016/j.scitotenv.2021.148583

Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold

Bojarska, Joanna, Mieczkowski, Adam, Ziora, Zyta, Skwarczynski, Mariusz, Toth, Istvan, Shalash, Ahmed O., Parang, Keykavous, El-Mowafi, Shaima A., Mohammed, Eman H. M., Elnagdy, Sherif, AlKhazindar, Maha and Wolf, Wojciech M. (2021). Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold. Biomolecules, 11 (10) 1515, 1515. doi: 10.3390/biom11101515

Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections

Alharthi, Sitah, Ebrahim Alavi, Seyed, Michael Moyle, Peter and Maria Ziora, Zyta (2021). Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections. Drug Discovery Today, 26 (9), 2164-2172. doi: 10.1016/j.drudis.2021.03.019

Formulation and antibacterial activity evaluation of quaternized aminochitosan membrane for wound dressing applications

Omer, Ahmed M., Tamer, Tamer M., Khalifa, Randa E., Eltaweil, Abdelazeem S., Agwa, Mona M., Sabra, Sally, Abd-Elmonem, Mahmoud S., Mohy-Eldin, Mohamed S. and Ziora, Zyta M. (2021). Formulation and antibacterial activity evaluation of quaternized aminochitosan membrane for wound dressing applications. Polymers, 13 (15) 2428, 1-20. doi: 10.3390/polym13152428

ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections

Naseri, Mahdi, Ziora, Zyta M., Simon, George P. and Batchelor, Warren (2021). ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections. Reviews in Medical Virology, 32 (2) e2263, 1-17. doi: 10.1002/rmv.2263

Bio-potency and molecular docking studies of isolated compounds from Grewia optiva J.R. Drumm. ex Burret

Ul Bari, Wasim, Ur Rehman, Najeeb, Khan, Ajmal, Ahsan Halim, Sobia, Yuan, Ye, Blaskovich, Mark A.T., Ziora, Zyta M., Zahoor, Muhammad, Naz, Sumaira, Ullah, Riaz, Alotaibi, Amal and Al-Harrasi, Ahmed (2021). Bio-potency and molecular docking studies of isolated compounds from Grewia optiva J.R. Drumm. ex Burret. Molecules, 26 (7) 2019, 2019. doi: 10.3390/molecules26072019

Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow eelease of curcumin

Omer, Ahmed M., Ziora, Zyta M., Tamer, Tamer M., Khalifa, Randa E., Hassan, Mohamed A., Mohy-Eldin, Mohamed S. and Blaskovich, Mark A. T. (2021). Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow eelease of curcumin. Molecules, 26 (2) 449, 1-14. doi: 10.3390/molecules26020449

Current perspective of innovative strategies for bioremediation of organic pollutants from wastewater

Jain, Marut, Khan, Sadaf Aiman, Sharma, Komal, Jadhao, Prashant Ram, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Current perspective of innovative strategies for bioremediation of organic pollutants from wastewater. Bioresource Technology, 344 (Pt B) 126305, 126305. doi: 10.1016/j.biortech.2021.126305

Syzygium cumini(L.),Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties

Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Yuan, Ye, Ahmad, Naveed, Tawab, Abdul, Ismail, Amir, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark.A.T. and Ziora, Zyta M. (2021). Syzygium cumini(L.),Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties. Journal of Ethnopharmacology, 271 113805, 1-12. doi: 10.1016/j.jep.2021.113805

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies

Nazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722

Non-antibiotic antimicrobial agents to combat biofilm-forming bacteria

Cao, Yuxue, Naseri, Mahdi, He, Yan, Xu, Chun, Walsh, Laurence J. and Ziora, Zyta M. (2019). Non-antibiotic antimicrobial agents to combat biofilm-forming bacteria. Journal of Global Antimicrobial Resistance, 21, 445-451. doi: 10.1016/j.jgar.2019.11.012

Tyrosinase inhibitors as potential antibacterial agents

Yuan, Ye, Jin, Wanli, Nazir, Yasir, Fercher, Christian, Thomas Blaskovich, Mark A., Cooper, Matthew A., Barnard, Ross T. and Ziora, Zyta M. (2019). Tyrosinase inhibitors as potential antibacterial agents. European Journal of Medicinal Chemistry, 187 111892, 111892. doi: 10.1016/j.ejmech.2019.111892

Quinolone antibiotics

Pham, Thu D. M., Ziora, Zyta M. and Blaskovich, Mark A. T. (2019). Quinolone antibiotics. MedChemComm, 10 (10), 1719-1739. doi: 10.1039/c9md00120d

Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017)

Sim, Wilson, Barnard, Ross, Blaskovich, M.A.T. and Ziora, Zyta (2018). Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017). Antibiotics, 7 (4) 93, 93. doi: 10.3390/antibiotics7040093

Silver bullets: a new lustre on an old antimicrobial agent

Möhler, Jasper S., Sim, Wilson, Blaskovich, Mark A. T., Cooper, Matthew A. and Ziora, Zyta M. (2018). Silver bullets: a new lustre on an old antimicrobial agent. Biotechnology Advances, 36 (5), 1391-1411. doi: 10.1016/j.biotechadv.2018.05.004

Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites

Naseri-Nosar, Mahdi and Ziora, Zyta Maria (2018). Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites. Carbohydrate Polymers, 189, 379-398. doi: 10.1016/j.carbpol.2018.02.003

Biological applications of Ru(II) polypyridyl complexes

Mital, Mariusz and Ziora, Zyta (2018). Biological applications of Ru(II) polypyridyl complexes. Coordination Chemistry Reviews, 375, 434-458. doi: 10.1016/j.ccr.2018.02.013

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies

Möhler, Jasper S., Kolmar, Theresa, Synnatschke, Kevin, Hergert, Marcel, Wilson, Liam A., Ramu, Soumya, Elliott, Alysha G., Blaskovich, Mark A.T., Sidjabat, Hanna E., Paterson, David L., Schenk, Gerhard, Cooper, Matthew A. and Ziora, Zyta M. (2017). Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies. Journal of Inorganic Biochemistry, 167, 134-141. doi: 10.1016/j.jinorgbio.2016.11.028

Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation

Azmi, Fazren, Elliott, Alysha G., Marasini, Nirmal, Ramu, Soumya, Ziora, Zyta, Kavanagh, Angela M., Blaskovich, Mark A. T., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2016). Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation. Bioorganic and Medicinal Chemistry, 24 (10), 2235-2241. doi: 10.1016/j.bmc.2016.03.053

Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials

Hang, Zhou, Cooper, Matthew A. and Ziora, Zyta M. (2016). Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials. Biochemical Compounds, 4. doi: 10.7243/2052-9341-4-2

Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine

McRae, Jacqui M., Ziora, Zyta M., Kassara, Stella, Cooper, Matthew A. and Smith, Paul A. (2015). Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine. Journal of Agricultural and Food Chemistry, 63 (17), 4345-4352. doi: 10.1021/acs.jafc.5b00758

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f

Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses

Simerska, Pavla, Suksamran, Tittaya, Ziora, Zyta Maria, Rivera, Fabian de Labastida, Engwerda, Christian and Toth, Istvan (2014). Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses. Vaccine, 32 (37), 4743-4750. doi: 10.1016/j.vaccine.2014.06.049

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267

Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system

Simerska, Pavla, Ziora, Zyta Maria, Fagan, Vincent, Goodwin, Daryn, Edrous, Farrah and Toth, Istvan (2013). Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system. Drug Delivery and Translational Research, Online First (3), 1-10. doi: 10.1007/s13346-013-0173-8

Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer

Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2013). Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules, 14 (8), 2798-2806. doi: 10.1021/bm400626w

pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform

Skwarczynski, Mariusz, Kowapradit, Jariya, Ziora, Zyta Maria and Toth, Istvan (2013). pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform. Biochemical Compounds, 1. doi: 10.7243/2052-9341-1-2

Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes

Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Ziora, Zyta M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2012). Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes. Journal of Medicinal Chemistry, 55 (19), 8515-8523. doi: 10.1021/jm301074n

Lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448

ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids

Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2012). ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids. ChemInform, 43 (25), no-no. doi: 10.1002/chin.201225259

Lipopeptides for the fragment-based pharmaceutics design

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2012). Lipopeptides for the fragment-based pharmaceutics design. International Journal of Organic Chemistry, 2 (01), 75-81. doi: 10.4236/ijoc.2012.21013

Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2011). Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery. Carbohydrate Research, 346 (12), 1439-1444. doi: 10.1016/j.carres.2011.03.019

Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers

Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Ziora, Zyta M., Monteiro, Michael J. and Toth, Istvan (2011). Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers. Biomacromolecules, 12 (4), 1339-1348. doi: 10.1021/bm200116z

Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein

Skwarczynski, Mariusz, Ahmad Fuaad, Abdullah A. H., Rustanti, Lina, Ziora, Zyta M., Aqil, Mohammed, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2011). Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein. Drug Delivery Letters, 1 (1), 2-8. doi: 10.2174/2210304X11101010002

ChemInform Abstract: Reactions of N-Phthalylamino Acid Chlorides with Trialkyl Phosphites

Ziora, Zyta, Maly, Alina, Lejczak, Barbara, Kafarski, Pawel, Holband, Jolanta and Wojcik, Grazyna (2010). ChemInform Abstract: Reactions of N-Phthalylamino Acid Chlorides with Trialkyl Phosphites. ChemInform, 31 (28), 1-1. doi: 10.1002/chin.200028203

Tetrapeptides, as small-sized peptidic inhibitors; Synthesis and their inhibitory activity against BACE1

Kakizawa, Taeko, Hidaka, Koushi, Hamada, Daisuke, Yamaguchi, Ryoji, Uemura, Tsuyoshi, Kitamura, Hitomi, Tagad, Harichandra D., Hamada, Takashi, Ziora, Zyta, Hamada, Yoshio, Kimura, Tooru and Kiso, Yoshiaki (2010). Tetrapeptides, as small-sized peptidic inhibitors; Synthesis and their inhibitory activity against BACE1. Journal of Peptide Science, 16 (6), 257-262. doi: 10.1002/psc.1238

In vitro and in vivo evaluation of positively charged liposaccharide derivatives as oral absorption enhancers for the delivery of anionic drugs

Bergeon, Julie A., Ziora, Zyta M., Abdelrahim, Adel S., Pernevi, Niklas, Moss, Anne R. and Toth, Istvan (2010). In vitro and in vivo evaluation of positively charged liposaccharide derivatives as oral absorption enhancers for the delivery of anionic drugs. Journal of Pharmaceutical Sciences, 99 (5), 2333-2342. doi: 10.1002/jps.21999

Thymine, adenine and lipoamino acid based gene delivery systems

Skwarczynski, Mariusz, Ziora, Zyta M., Coles, Daniel J., Lin, I-Chun and Toth, Istvan (2010). Thymine, adenine and lipoamino acid based gene delivery systems. Chemical Communications, 46 (18), 3140-3142. doi: 10.1039/b924371b

Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery

Abdelrahim, Adel. S., Ziora, Zyta M., Bergeon, Julie A., Moss, Anne R. and Toth, Istvan (2009). Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery. Tetrahedron, 65 (45), 9436-9442. doi: 10.1016/j.tet.2009.08.072

Amidoalkylation of Phosphorus Trichloride with Acetamide and Alkyl Oxocycloalkanecarboxylates

Ziora, Zyta and Kafarski, Pawel (2009). Amidoalkylation of Phosphorus Trichloride with Acetamide and Alkyl Oxocycloalkanecarboxylates. Phosphorus, Sulfur, and Silicon and the Related Elements, 184 (4), 1047-1053. doi: 10.1080/10426500902737356

Potent antimalarial activity of 2-aminopyridinium salts, amidines, and guanidines

Calas, Michele, Outtara, Mahama, Piquet, Giles, Ziora, Zyta, Bordat, Y., Ancelin, Marie L., Escale, Roger and Vial, Henri (2007). Potent antimalarial activity of 2-aminopyridinium salts, amidines, and guanidines. Journal of Medicinal Chemistry, 50 (25), 6307-6315. doi: 10.1021/jm0704752

Effect of unsaturated bonds in the sn-2 acyl chain of phosphatidylcholine on the membrane-damaging action of Clostridium perfringens alpha-toxin toward liposomes

Nagahama, Masahiro, Otsuka, Akiko, Oda, Masataka, Singh, Rajesh K., Ziora, Zyta M., Imagawa, Hiroshi, Nishizawa, Mugio and Sakurai, Jun (2007). Effect of unsaturated bonds in the sn-2 acyl chain of phosphatidylcholine on the membrane-damaging action of Clostridium perfringens alpha-toxin toward liposomes. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1768 (11), 2940-2945. doi: 10.1016/j.bbamem.2007.08.016

Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4(phenylthio)butyric acid

Ziora, Zyta, Kasai, Soko, Hidaka, Koushi, Nagamine, Ayaka, Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2007). Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4(phenylthio)butyric acid. Bioorganic and Medicinal Chemistry Letters, 17 (6), 1629-1633. doi: 10.1016/j.bmcl.2006.12.097

beta-Secretase inhibitors: Modification at the P-4 position and improvement of inhibitory activity in cultured cells

Hamada, Yoshio, Igawa, Naoto, Ikari, Hayato, Ziora, Zyta, Nguyen, Jeffrey-Tri, Yamani, Abdellah, Hidaka, Koushi, Kimura, Tooru, Saito, Kazuki, Hayashi, Yoshio, Ebina, Maiko, Ishiura, Shoichi and Kiso, Yoshiaki (2006). beta-Secretase inhibitors: Modification at the P-4 position and improvement of inhibitory activity in cultured cells. Bioorganic and Medicinal Chemistry Letters, 16 (16), 4354-4359. doi: 10.1016/j.bmcl.2006.05.046

Phenylthionorstatine as a transition-state mimic in BACE1 inhibitors

Ziora Zyta, Kasai Soko, Hidaka Koushi, Nagamine Ayaka, Kimura Tooru, Saito K., Hayashi Yoshio and Kiso Yoshiaki (2006). Phenylthionorstatine as a transition-state mimic in BACE1 inhibitors. Peptide Science, 2006, 237-238.

Small-sized BACE1 inhibitors

Zyta, Ziora, Tooru, KImura and Yoshiaki, Kiso (2006). Small-sized BACE1 inhibitors. Drugs of the Future, 31 (1), 53-63. doi: 10.1358/dof.2006.031.01.957326

Conformational polymorphism of diethyl 1-(phthalylglycyloxy)-2-phthalylaminoethenephosphonate

Holband, J, Wojcik, G, Ziora, Z and Kafarski, P (2001). Conformational polymorphism of diethyl 1-(phthalylglycyloxy)-2-phthalylaminoethenephosphonate. Journal of Molecular Structure, 595 (1-3), 167-174. doi: 10.1016/S0022-2860(01)00521-X

Synthesis and spectroscopic characterization of protected N-phosphonomethylglycine dipeptides

Ziora, Zyta, Kafarski, Pawel, Holband, Jolanta and Wojcik, Grazyna (2001). Synthesis and spectroscopic characterization of protected N-phosphonomethylglycine dipeptides. Journal of Peptide Science, 7 (9), 466-473. doi: 10.1002/psc.340

H-1 NMR studies of rotational isomerism in phosphonic analogues of aspartic acid

Jedrzejczyk, D, Ziora, Z and Kafarski, P (2000). H-1 NMR studies of rotational isomerism in phosphonic analogues of aspartic acid. Magnetic Resonance in Chemistry, 38 (5), 370-374. doi: 10.1002/1097-458x(200005)38:5<370::aid-mrc651>3.0.co;2-m

Reactions of N-phthalylamino acid chlorides with trialkyl phosphites

Ziora, Zyta, Maly, Alina, Lejczak, Barbara, Kafarski, Pawel, Holband, Jolanta and W�jcik, Gra?yna (2000). Reactions of N-phthalylamino acid chlorides with trialkyl phosphites. Heteroatom Chemistry, 11 (3), 232-239. doi: 10.1002/(sici)1098-1071(2000)11:3<232::aid-hc12>3.0.co;2-u

Synthesis of triethyl N-formyl-N-phosphonomethylglycinate and diethyl N-formyl-N- phosphonomethylglycine and studies of their rotational conformers by dynamic NMR

Ziora, Z, Cierpicki, T, Grembecka, J and Kafarski, P (1999). Synthesis of triethyl N-formyl-N-phosphonomethylglycinate and diethyl N-formyl-N- phosphonomethylglycine and studies of their rotational conformers by dynamic NMR. Journal of Chemical Research (2), 68-69A. doi: 10.1039/a806474a

Reaction of N-Phtalylamino Acid Chlorides with Trialkyl Phosphites

Ziora, Zyta, Maly, Alina, Lejczak, Barbara and Kafarski, Paweł (1999). Reaction of N-Phtalylamino Acid Chlorides with Trialkyl Phosphites. Phosphorus, Sulfur, and Silicon and the Related Elements, 147 (1), 145-145. doi: 10.1080/10426509908053553

Synthesis of therapeutic vaccine against cervical cancer

Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.

Nanoparticles-based peptide subunit vaccines against group A Streptococcus

Skwarczynski, M., Fuaad, A. A. H. A., Zaman, M., Jia, Z., Kowapradit, J., Rustanti, L., Ziora, Z. M., Monteiro, M. L. J., Batzloff, M. R., Goodc, M. F. and Toth, I. (2012). Nanoparticles-based peptide subunit vaccines against group A Streptococcus. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

New glycopeptidic antibiotics to combat multidrug resistant pathogens

Gong, Y., Muldoon, C. A., Premraj, R., Ziora, Z. M., Bradford, T. A., Cheng, M., Ramu, S., Huang, J. X., Kavanagh, A., Pelingon, R., Lee, J. C., Wong, K., Butler, M. S., Blaskovich, M. A. and Cooper, M. A. (2012). New glycopeptidic antibiotics to combat multidrug resistant pathogens. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2449

Modification of P4 position in beta-Secretase (BACE1) inhibitors containing phenylnorstatine

Ziora, Zyta, Shuto, Daisuke, Kasai, Soko, Liu, Ping, Hidaka, Koushi, Igawa, Nagai, Nagamine, Ayaka, Stochaj, Monika, Hamada, Takashi, Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2006). Modification of P4 position in beta-Secretase (BACE1) inhibitors containing phenylnorstatine. 42nd Japanese Peptide Symposium, Osaka, Japan, 27-29 October 2005. Osaka, Japan: Japanese Peptide Society.

A novel approach for the hydrophobic peptides synthesis and purification through O-N intramolecular acyl migration reaction

Sohma, Youhei, Sasaki, Masato, Ziora, Zyta, Takahashi, N., Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2004). A novel approach for the hydrophobic peptides synthesis and purification through O-N intramolecular acyl migration reaction. 18th American Peptide Symposium, Boston, MA, U.S.A., 19-23 July 2003. San Diego, CA, U.S.A.: American Peptide Society.