The University of Queensland

Therapeutic perspectives in Type-1 Diabetes

Singh, Prachi, Kokil, Ganesh R., Tupally, Karnaker R., Poddar, Kingshuk, Tan, Aaron, Venkatesan, Venky, Parekh, Harendra S. and Pastorin, Giorgia (2016). Therapeutic perspectives in Type-1 Diabetes. Singapore: Springer. doi: 10.1007/978-981-10-0602-9

Introduction to diabetes and type 1 diabetes

Singh, Prachi, Kokil, Ganesh R., Tupally, Karnaker R., Poddar, Kingshuk, Tan, Aaron, Venkatesan, Venky, Parekh, Harendra S. and Pastorin, Giorgia (2016). Introduction to diabetes and type 1 diabetes. Therapeutic perspectives in type-1 diabetes. (pp. 1-6) edited by Prachi Singh, Ganesh R. Kokil, Karnaker R. Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh and Giorgia Pastorin. Singapore, Singapore: Springer. doi: 10.1007/978-981-10-0602-9_1

Peptide dendrimers in delivery of bioactive molecules to skin

Manikkath, J., Hegde, A. R., Parekh, H. S. and Mutalik, S. (2016). Peptide dendrimers in delivery of bioactive molecules to skin. Nanoscience in dermatology. (pp. 89-97) edited by Michael R. Hamblin, Pinar Avci and Tarl W. Prow. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-802926-8.00007-0

Dendrimers

Tupally, Karnaker R., Kokil, Ganesh K., Thakur, Sachin S., Singh, Prachi and Parekh, Harendra S. (2015). Dendrimers. Controlled release systems: advances in nanobottles and active nanoparticles. (pp. 259-286) edited by Alexander van Herk, Jacqueline Forcada and Giorgia Pastorin. Boca Raton, FL, United States: Taylor & Francis. doi: 10.1201/b19860-15

Solubilization of poorly-soluble drugs: cyclodextrin-based formulations

Thakur, Sachin S., Parekh, Harendra S., Schwable, Carl H., Gan, Yong and Ouyang, Defang (2015). Solubilization of poorly-soluble drugs: cyclodextrin-based formulations. Computational pharmaceutics: application of molecular modeling in drug delivery. (pp. 31-51) edited by Defang Ouyang and Sean C. Smith. Chichester, United Kingdom: John Wiley & Sons.

A new dawn for the use of traditional Chinese medicine in cancer therapy

Parekh, Harendra S., Liu, Gang and Wei, Ming Q. (2014). A new dawn for the use of traditional Chinese medicine in cancer therapy. Recent advances in plant-based, traditional, and natural medicines. (pp. 131-150) edited by Subramayam Vemulpad and Joanne Jamie. Oakville, ON, Canada: Apple Academic Press.

Fluorescent nucleic acid probes in living cells

Seefeld, Anne, Kokil, Ganesh R., Tupally, Karnaker R., Parekh, Harendra S. and Herten, Dirk-Peter (2013). Fluorescent nucleic acid probes in living cells. DNA and RNA nanobiotechnologies in medicine: diagnosis and treatment of diseases. (pp. 291-328) edited by Volker A. Erdmann and Jan Barciszewski. Berlin, Germany: Springer. doi: 10.1007/978-3-642-36853-0_12

An evidence-based perspective of herbal remedies for cancer patients

Parekh, Harendra S. and Jing, Jing (2011). An evidence-based perspective of herbal remedies for cancer patients. Evidence-based Anticancer Materia Medica. (pp. 399-422) B.V.: Springer.

An evidence-based perspective of herbal remedies for cancer patients.

Parekh, Harendra S. and Jing, Jing (2011). An evidence-based perspective of herbal remedies for cancer patients.. Evidence-based anticancer herbal medicine. (pp. 399-422) edited by William C.S. Cho. New York, U.S.A.: Springer Verlag.

An introduction to dendrimers-versatile drug/gene delivery vectors

Parekh, H. S (2011). An introduction to dendrimers-versatile drug/gene delivery vectors. Nanotechnology in health care. (pp. 355-367) edited by P.D. Gupta and N. Udupa. Nataniyon Ka Rasta, Jaipur: S.P. Publications.

Dendrimers as carriers for the effective delivery of drugs and genes

Shah, Neha, Ouyang, Defang, Mutalik, Srinivas and Parekh, Harendra (2011). Dendrimers as carriers for the effective delivery of drugs and genes. Nanotechnology in health care. (pp. 367-391) edited by P.D. Gupta and N. Udupa. Jaipur, India: S.P. Publications.

Ameliorative anticancer effect of dendrimeric peptide modified liposomes of letrozole: In vitro and in vivo performance evaluations

Hegde, Aswathi R., Paul, Milan, Kumbham, Soniya, Roy, Amrita Arup, Ahmad, Sheikh F., Parekh, Harendra, Biswas, Swati and Mutalik, Srinivas (2023). Ameliorative anticancer effect of dendrimeric peptide modified liposomes of letrozole: In vitro and in vivo performance evaluations. International Journal of Pharmaceutics, 648 123582, 123582. doi: 10.1016/j.ijpharm.2023.123582

Anti-CD4 antibody and dendrimeric peptide based targeted nano-liposomal dual drug formulation for the treatment of HIV infection

Mutalik, Sadhana P., Gaikwad, Shraddha Y., Fernandes, Gasper, More, Ashwini, Kulkarni, Sanjay, Fayaz, Shaik Mohammad Abdul, Tupally, Karnaker, Parekh, Harendra S., Kulkarni, Smita, Mukherjee, Anupam and Mutalik, Srinivas (2023). Anti-CD4 antibody and dendrimeric peptide based targeted nano-liposomal dual drug formulation for the treatment of HIV infection. Life Sciences, 334 122226, 122226. doi: 10.1016/j.lfs.2023.122226

Opportunities for Bioactive Glass in Gastrointestinal Conditions: A Review of Production Methodologies, Morphology, Composition, and Performance

Harrop, Angus C. F., Tupally, Karnaker R., Pandey, Preeti and Parekh, Harendra S. (2023). Opportunities for Bioactive Glass in Gastrointestinal Conditions: A Review of Production Methodologies, Morphology, Composition, and Performance. Molecular Pharmaceutics. doi: 10.1021/acs.molpharmaceut.3c00188

Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis

Bakshi, Shrishty, Pandey, Preeti, Mohammed, Yousuf, Wang, Joanna, Sailor, Michael J., Popat, Amirali, Parekh, Harendra S. and Kumeria, Tushar (2023). Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis. Journal of Controlled Release, 363, 452-463. doi: 10.1016/j.jconrel.2023.09.045

Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy

Lohman, Rink-Jan, Reddy Tupally, Karnaker, Kandale, Ajit, Cabot, Peter J. and Parekh, Harendra S. (2023). Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy. Frontiers in Pharmacology, 14 1150313, 1-16. doi: 10.3389/fphar.2023.1150313

A systematic review of ultrasound-mediated drug delivery to the eye and critical insights to facilitate a timely path to the clinic

Rad, Isaac J., Chapman, Luke, Tupally, Karnaker Reddy, Veidt, Martin, Al-Sadiq, Hussain, Sullivan, Robert and Parekh, Harendra S (2023). A systematic review of ultrasound-mediated drug delivery to the eye and critical insights to facilitate a timely path to the clinic. Theranostics, 13 (11), 3582-3638. doi: 10.7150/thno.82884

Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy

Lohman, Rink-Jan, Tupally, Karnaker Reddy, Kandale, Ajit, Cabot, Peter J. and Parekh, Harendra S. (2022). Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy. British Journal of Pharmacology, 180 (1), 129-129. doi: 10.1111/bph.15862

Fabrication and Characterization of Clozapine Nanoemulsion Sol–Gel for Intranasal Administration

Tan, Madeleine S. A., Pandey, Preeti, Lohman, Rink-Jan, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2022). Fabrication and Characterization of Clozapine Nanoemulsion Sol–Gel for Intranasal Administration. Molecular Pharmaceutics, 19 (11), 4055-4066. doi: 10.1021/acs.molpharmaceut.2c00513

Application of sol–gels for treatment of gynaecological conditions—physiological perspectives and emerging concepts in intravaginal drug delivery

Thapa, Ritu, Gurung, Shila, Parat, Marie-Odile, Parekh, Harendra S. and Pandey, Preeti (2022). Application of sol–gels for treatment of gynaecological conditions—physiological perspectives and emerging concepts in intravaginal drug delivery. Gels, 8 (2) 99, 99. doi: 10.3390/gels8020099

Clozapine-encapsulated binary mixed micelles in thermosensitive sol–gels for intranasal administration

Tan, Madeleine S. A., Pandey, Preeti, Falconer, James R., Siskind, Dan J., Balmanno, Alexandra and Parekh, Harendra S. (2022). Clozapine-encapsulated binary mixed micelles in thermosensitive sol–gels for intranasal administration. Gels, 8 (1) 38, 38. doi: 10.3390/gels8010038

Fractional factorial design study for the extraction of cannabinoids from CBD-dominant cannabis flowers by supercritical carbon dioxide

Qamar, Sadia, Torres, Yady J. M., Parekh, Harendra S. and Falconer, James Robert (2022). Fractional factorial design study for the extraction of cannabinoids from CBD-dominant cannabis flowers by supercritical carbon dioxide. Processes, 10 (1) 93. doi: 10.3390/pr10010093

Multi-physics study of acoustofluidic delivery agents' clustering behavior

AlSadiq, Hussain, Tupally, Karnaker Reddy, Vogel, Robert, Parekh, Harendra S. and Veidt, Martin (2022). Multi-physics study of acoustofluidic delivery agents' clustering behavior. Physics in Medicine and Biology, 67 (1) 015002, 015002. doi: 10.1088/1361-6560/ac4666

Effects of ethanol on the supercritical carbon dioxide extraction of cannabinoids from near equimolar (THC and CBD balanced) cannabis flower

Qamar, Sadia, Torres, Yady J. M., Parekh, Harendra S. and Falconer, James Robert (2021). Effects of ethanol on the supercritical carbon dioxide extraction of cannabinoids from near equimolar (THC and CBD balanced) cannabis flower. Separations, 8 (9) 154, 154. doi: 10.3390/separations8090154

Impact of different emollient esters on body emulsions: sensory, physicochemical, and biometrological characterization

Fabbron-Appas, Catherine Tolomei, Pandey, Preeti, Parekh, Harendra S., Sales, Caroline Cianga, Duque, Marcelo Dutra, Andreo-Filho, Newton, Lopes, Patricia Santos, de Noronha, Regina Lucia F. and Leite-Silva, Vania Rodrigues (2021). Impact of different emollient esters on body emulsions: sensory, physicochemical, and biometrological characterization. Journal of Sensory Studies, 36 (4) e12660. doi: 10.1111/joss.12660

Development and optimization of supercritical fluid extraction setup leading to quantification of 11 cannabinoids derived from medicinal cannabis

Qamar, Sadia, Manrique, Yady J., Parekh, Harendra S. and Falconer, James R. (2021). Development and optimization of supercritical fluid extraction setup leading to quantification of 11 cannabinoids derived from medicinal cannabis. Biology, 10 (6) 481, 1-20. doi: 10.3390/biology10060481

Extraction of medicinal cannabinoids through supercritical carbon dioxide technologies: a review

Qamar, Sadia, Torres, Yady J.M., Parekh, Harendra S. and Falconer, James Robert (2021). Extraction of medicinal cannabinoids through supercritical carbon dioxide technologies: a review. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1167 122581, 1-10. doi: 10.1016/j.jchromb.2021.122581

A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions

Tan, Madeleine S. A., Honarparvar, Faraz, Falconer, James R., Parekh, Harendra S., Pandey, Preeti and Siskind, Dan J. (2021). A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions. Psychopharmacology, 238 (3), 615-637. doi: 10.1007/s00213-020-05746-y

Shell properties and concentration stability of acoustofluidic delivery agents

Alsadiq, Hussain, Tupally, Karnaker, Vogel, Robert, Kokil, Ganesh, Parekh, Harendra S. and Veidt, Martin (2021). Shell properties and concentration stability of acoustofluidic delivery agents. Physical and Engineering Sciences in Medicine, 44 (1), 79-91. doi: 10.1007/s13246-020-00954-4

Evaluation of microalgae and cyanobacteria as potential sources of antimicrobial compounds

Alsenani, Faisal, Tupally, Karnaker R., Chua, Elvis T., Eltanahy, Eladl, Alsufyani, Hamed, Parekh, Harendra S. and Schenk, Peer M. (2020). Evaluation of microalgae and cyanobacteria as potential sources of antimicrobial compounds. Saudi Pharmaceutical Journal, 28 (12), 1834-1841. doi: 10.1016/j.jsps.2020.11.010

Surface-engineered nanoliposomes with lipidated and non-lipidated peptide-dendrimeric scaffold for efficient transdermal delivery of a therapeutic agent: Development, characterization, toxicological and preclinical performance analyses

Manikkath, Jyothsna, Parekh, Harendra S. and Mutalik, Srinivas (2020). Surface-engineered nanoliposomes with lipidated and non-lipidated peptide-dendrimeric scaffold for efficient transdermal delivery of a therapeutic agent: Development, characterization, toxicological and preclinical performance analyses. European Journal of Pharmaceutics and Biopharmaceutics, 156, 97-113. doi: 10.1016/j.ejpb.2020.09.001

Nose-to-brain delivery of antipsychotics using nanotechnology: a review

Tan, Madeleine S. A., Parekh, Harendra S., Pandey, Preeti, Siskind, Dan J. and Falconer, James R. (2020). Nose-to-brain delivery of antipsychotics using nanotechnology: a review. Expert Opinion on Drug Delivery, 17 (6) 17425247.2020.1762563, 839-853. doi: 10.1080/17425247.2020.1762563

Cell membrane penetration without pore formation: chameleonic properties of dendrimers in response to hydrophobic and hydrophilic environments

de Luca, Sergio, Seal, Prasenjit, Parekh, Harendra S., Tupally, Karnaker R. and Smith, Sean C. (2020). Cell membrane penetration without pore formation: chameleonic properties of dendrimers in response to hydrophobic and hydrophilic environments. Advanced Theory and Simulations, 3 (7) 1900152, 1900152. doi: 10.1002/adts.201900152

Nuts, cereals, seeds and legumes proteins derived emulsifiers as a source of plant protein beverages: a review

Qamar, Sadia, Manrique, Yady J., Parekh, Harendra and Falconer, James Robert (2019). Nuts, cereals, seeds and legumes proteins derived emulsifiers as a source of plant protein beverages: a review. Critical Reviews in Food Science and Nutrition, 60 (16), 1-21. doi: 10.1080/10408398.2019.1657062

Toxicity evaluation and nasal mucosal tissue deposition of dexamethasone-infused mucoadhesive in situ nasal gelling systems

Pandey, Preeti, Pandey, Saurabh, Cabot, Peter J., Wallwork, Benjamin, Panizza, Benedict J. and Parekh, Harendra S. (2019). Toxicity evaluation and nasal mucosal tissue deposition of dexamethasone-infused mucoadhesive in situ nasal gelling systems. Saudi Pharmaceutical Journal, 27 (7), 914-919. doi: 10.1016/j.jsps.2019.06.005

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D. and Parekh, Harendra S. (2019). Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 136, 102-107. doi: 10.1016/j.ejpb.2019.01.014

Development of a hybrid peptide dendrimer micellar carrier system and its application in the reformulation of a hydrophobic therapeutic agent derived from traditional Chinese medicine

Jing, Jing, Tupally, Karnaker R., Kokil, Ganesh R., Qu, Zhi, Chen, Sibao and Parekh, Harendra S. (2019). Development of a hybrid peptide dendrimer micellar carrier system and its application in the reformulation of a hydrophobic therapeutic agent derived from traditional Chinese medicine. RSC Advances, 9 (5), 2458-2463. doi: 10.1039/c8ra09606f

Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery

Kokil, Ganesh R., Veedu, Rakesh N., Le, Bao Tri, Ramm, Grant A. and Parekh, Harendra S. (2018). Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports, 8 (1) 4832, 4832. doi: 10.1038/s41598-018-22902-9

Development and Evaluation of Lipid Nanoparticles Containing Natural Botanical Oil for Sun Protection: Characterization and in vitro and in vivo Human Skin Permeation and Toxicity

Andréo-Filho, Newton, Bim, Antonio Vinicius Kosiski, Kaneko, Telma Mary, Kitice, Nidia Ayumi, Haridass, Isha N., Abd, Eman, Santos Lopes, Patricia, Thakur, Sachin S., Parekh, Harendra S., Roberts, Michael S., Grice, Jeffrey E., Benson, Heather A.E. and Leite-Silva, Vânia Rodrigues (2018). Development and Evaluation of Lipid Nanoparticles Containing Natural Botanical Oil for Sun Protection: Characterization and in vitro and in vivo Human Skin Permeation and Toxicity. Skin Pharmacology and Physiology, 31 (1), 1-9. doi: 10.1159/000481691

High-Resolution Single Particle Zeta Potential Characterisation of Biological Nanoparticles using Tunable Resistive Pulse Sensing

Vogel, Robert, Pal, Anoop K, Jambhrunkar, Siddharth, Patel, Pragnesh, Thakur, Sachin S, Reátegui, Eduardo, Parekh, Harendra S, Saá, Paula, Stassinopoulos, Adonis and Broom, Murray F (2017). High-Resolution Single Particle Zeta Potential Characterisation of Biological Nanoparticles using Tunable Resistive Pulse Sensing. Scientific reports, 7 (1) 17479, 17479. doi: 10.1038/s41598-017-14981-x

Skin delivery of EGCG and silibinin: potential of peptide dendrimers for enhanced skin permeation and deposition

Shetty, Pallavi Krishna, Manikkath, Jyothsna, Tupally, Karnaker, Kokil, Ganesh, Hegde, Aswathi R., Raut, Sushil Y., Parekh, Harendra S. and Mutalik, Srinivas (2017). Skin delivery of EGCG and silibinin: potential of peptide dendrimers for enhanced skin permeation and deposition. AAPS PharmSciTech, 18 (6), 2346-2357. doi: 10.1208/s12249-017-0718-0

Peptide dendrimer-conjugates of ketoprofen: synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery

Hegde, Aswathi R., Rewatkar, Prarthana V., Manikkath, Jyothsna, Tupally, Karnaker, Parekh, Harendra S. and Mutalik, Srinivas (2017). Peptide dendrimer-conjugates of ketoprofen: synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery. European Journal of Pharmaceutical Sciences, 102, 237-249. doi: 10.1016/j.ejps.2017.03.009

Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina

Thakur, Sachin S., Ward, Micheal S., Popat, Amirali, Flemming, Nicole B., Parat, Marie-Odile, Barnett, Nigel L. and Parekh, Harendra S. (2017). Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina. Plos One, 12 (5) e0178305, e0178305. doi: 10.1371/journal.pone.0178305

Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen

Manikkath, Jyothsna, Hegde, Aswathi R., Kalthur, Guruprasad, Parekh, Harendra S. and Mutalik, Srinivas (2017). Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen. International Journal of Pharmaceutics, 521 (1-2), 110-119. doi: 10.1016/j.ijpharm.2017.02.002

Formulation, functional evaluation and ex vivo performance of thermoresponsive soluble gels - a platform for therapeutic delivery to mucosal sinus tissue

Pandey, Preeti, Cabot, Peter J., Wallwork, Benjamin, Panizza, Benedict J. and Parekh, Harendra S. (2017). Formulation, functional evaluation and ex vivo performance of thermoresponsive soluble gels - a platform for therapeutic delivery to mucosal sinus tissue. European Journal of Pharmaceutical Sciences, 96, 499-507. doi: 10.1016/j.ejps.2016.10.017

Dynamical interactions of 5-fluorouracil drug with dendritic peptide vectors: the impact of dendrimer generation, charge, counterions, and structured water

De Luca, Sergio, Seal, Prasenjit, Ouyang, Defang, Parekh, Harendra S., Kannam, Sridhar Kumar and Smith, Sean C. (2016). Dynamical interactions of 5-fluorouracil drug with dendritic peptide vectors: the impact of dendrimer generation, charge, counterions, and structured water. Journal of Physical Chemistry B, 120 (25), 5732-5743. doi: 10.1021/acs.jpcb.6b00533

Express in vitro plasmid transfection achieved with 16+ asymmetric peptide dendrimers

Rewatkar, Prartana V., Sester, David P., Parekh, Harendra S. and Parat, Marie-Odile (2016). Express in vitro plasmid transfection achieved with 16+ asymmetric peptide dendrimers. ACS Biomaterials Science and Engineering, 2 (3), 438-445. doi: 10.1021/acsbiomaterials.6b00033

Molecular determinants of the cellular entry of asymmetric peptide dendrimers and role of caveolae

Rewatkar, Prartana V., Parekh, Harendra S. and Parat, Marie-Odile (2016). Molecular determinants of the cellular entry of asymmetric peptide dendrimers and role of caveolae. PLoS One, 11 (1) e0147491, e0147491.1-e0147491.15. doi: 10.1371/journal.pone.0147491

Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach

Soo, Ernest, Thakur, Sachin, Qu, Zhi, Jambhrunkar, Siddharth, Parekh, Harebdra S. and Popat, Amirali (2016). Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach. Journal of Colloid and Interface Science, 462, 368-374. doi: 10.1016/j.jcis.2015.10.022

Are caveolae a cellular entry route for non-viral therapeutic delivery systems?

Rewatkar, Prarthana V., Parton, Robert G., Parekh, Harendra S. and Parat, Marie-Odile (2015). Are caveolae a cellular entry route for non-viral therapeutic delivery systems?. Advanced Drug Delivery Reviews, 91, 92-108. doi: 10.1016/j.addr.2015.01.003

Particle size- and number-dependent delivery to cells by layered double hydroxide nanoparticles

Dong, Haiyan, Parekh, Harendra S. and Xu, Zhi Ping (2015). Particle size- and number-dependent delivery to cells by layered double hydroxide nanoparticles. Journal of Colloid And Interface Science, 437 (1), 10-16. doi: 10.1016/j.jcis.2014.09.010

Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics

Kokil, Ganesh R., Veedu, Rakesh N., Ramm, Grant A., Prins, Johannes B. and Parekh, Harendra S. (2015). Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics. Chemical Reviews, 115 (11), 4719-4743. doi: 10.1021/cr5002832

Biliary excretion of glycyrrhetinic acid: glucuronide-conjugate determination following a pharmacokinetic study of rat bile

Lu, Yang, Jing, Jing, Ren, Weichao, Zhu, Jing, Qiu, Zhixia, Li, Ning, Li, Xiaonan, Zhao, Di, Parekh, Harendra S. and Chen, Xijing (2014). Biliary excretion of glycyrrhetinic acid: glucuronide-conjugate determination following a pharmacokinetic study of rat bile. Phytotherapy Research, 28 (12), 1887-1889. doi: 10.1002/ptr.5170

Enhanced cellular delivery and biocompatibility of a small layered double hydroxide–liposome composite system

Dong, Haiyan, Parekh, Harendra S. and Xu, Zhi Ping (2014). Enhanced cellular delivery and biocompatibility of a small layered double hydroxide–liposome composite system. Pharmaceutics, 6 (4), 584-598. doi: 10.3390/pharmaceutics6040584

Engineering small MgAl-layered double hydroxide nanoparticles for enhanced gene delivery

Dong, Haiyan, Chen, Min, Rahman, Shafiur, Parekh, Harendra S., Cooper, Helen M. and Xu, Zhi Ping (2014). Engineering small MgAl-layered double hydroxide nanoparticles for enhanced gene delivery. Applied Clay Science, 100 (C), 66-75. doi: 10.1016/j.clay.2014.04.028

Intravitreal drug delivery in retinal disease: are we out of our depth?

Thakur, Sachin S., Barnett, Nigel L., Donaldson, Mark J. and Parekh, Harendra S. (2014). Intravitreal drug delivery in retinal disease: are we out of our depth?. Expert Opinion on Drug Delivery, 11 (10), 1575-1590. doi: 10.1517/17425247.2014.927864

Asymmetric peptide dendrimers are effective linkers for antibody-mediated delivery of diverse payloads to B cells in vitro and in vivo

Shah, Neha D., Parekh, Harendra S. and Steptoe, Raymond J. (2014). Asymmetric peptide dendrimers are effective linkers for antibody-mediated delivery of diverse payloads to B cells in vitro and in vivo. Pharmaceutical Research, 31 (11), 3150-3160. doi: 10.1007/s11095-014-1408-1

Enhancement in deposition and permeation of 5-fluorouracil through human epidermis assisted by peptide dendrimers.

Mutalik, Srinivas, Shetty, Pallavi K., Kumar, Aravind, Kalra, Rohit and Parekh, Harendra S. (2014). Enhancement in deposition and permeation of 5-fluorouracil through human epidermis assisted by peptide dendrimers.. Drug Delivery, 21 (1), 44-54. doi: 10.3109/10717544.2013.845861

The application of quantitative NMR for the facile, rapid and reliable determination of clindamycin phosphate in a conventional tablet formulation

Liang, Xianrui, Du, Liping, Su, Feng, Parekh, Harendra S. and Sua, Weike (2014). The application of quantitative NMR for the facile, rapid and reliable determination of clindamycin phosphate in a conventional tablet formulation. Magnetic Resonance in Chemistry, Early View (4), 1-5. doi: 10.1002/mrc.4048

Contributions of intestine and plasma to the presystemic bioconversion of Vicagrel, an acetate of clopidogrel

Qiu, Zhixia, Li, Ning, Song, Ling, Lu, Yang, Jing, Jing, Parekha, Harendra S., Gao, Wenchao, Tian, Fengjie, Wang, Xin, Ren, Shuangxia and Chen, Xijing (2013). Contributions of intestine and plasma to the presystemic bioconversion of Vicagrel, an acetate of clopidogrel. Pharmaceutical Research, 31 (1), 238-251. doi: 10.1007/s11095-013-1158-5

Rapid identification of primary constituents in parotoid gland secretions of the Australian cane toad using HPLC/MS-Q-TOF

Jing, Jing, Ren, Wei C., Li, Chun, Bose, Utpal, Parekh, Harendra S. and Wei, Ming Q. (2013). Rapid identification of primary constituents in parotoid gland secretions of the Australian cane toad using HPLC/MS-Q-TOF. Biomedical Chromatography, 27 (6), 685-687. doi: 10.1002/bmc.2858

Advances in analytical technologies to evaluate the quality of traditional Chinese medicines

Jing, Jing, Ren, Weichao, Chen, Si Bao, Wei, Ming and Parekh, Harendra S. (2013). Advances in analytical technologies to evaluate the quality of traditional Chinese medicines. Trends in Analytical Chemistry, 44, 39-45. doi: 10.1016/j.trac.2012.11.006

Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis

Mutalik, S., Parekh, H. S., Anissimov, Y. G., Grice, J. E. and Roberts, M. S. (2013). Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis. Skin Pharmacology and Physiology, 26 (3), 127-138. doi: 10.1159/000348469

Native and β-cyclodextrin-enclosed curcumin: entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer

Rahman, Shafiur, Cao, Siyu, Steadman, Kathryn J., Wei, Ming and Parekh, Harendra S. (2012). Native and β-cyclodextrin-enclosed curcumin: entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer. Drug Delivery, 19 (7), 346-353. doi: 10.3109/10717544.2012.721143

Sonophoresis-mediated permeation and retention of peptide dendrimers across human epidermis

Mutalik, Srinivas, Nayak, Usha Y., Kalra, Rohit, Kumar, Aravind, Kulkarni, Raghavendra V. and Parekh, Harendra (2012). Sonophoresis-mediated permeation and retention of peptide dendrimers across human epidermis. Skin Research and Technology, 18 (1), 101-107. doi: 10.1111/j.1600-0846.2011.00539.x

Development of an in-line HPLC fingerprint ion-trap mass spectrometric method for identification and quality control of Radix Scrophulariae

Jing, Jing, Chan, Chi-on, Xu, Lijia, Jin, Dengping, Cao, Xinwei, Mok, Daniel K. W., Parekh, H. S. and Chen, Sibao (2011). Development of an in-line HPLC fingerprint ion-trap mass spectrometric method for identification and quality control of Radix Scrophulariae. Journal of Pharmaceutical and Biomedical Analysis, 56 (4), 830-835. doi: 10.1016/j.jpba.2011.07.032

The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation

Ouyang, Defang, Zhang, Hong, Parekh, Harendra and Smith, Sean C. (2011). The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation. Biophysical Chemistry, 158 (2-3), 126-133. doi: 10.1016/j.bpc.2011.06.003

Low-generation asymmetric dendrimers exhibit minimal toxicity and effectively complex DNA

Shah, Neha, Steptoe, Raymond J. and Parekh, Harendra S. (2011). Low-generation asymmetric dendrimers exhibit minimal toxicity and effectively complex DNA. Journal of Peptide Science, 17 (6), 470-478. doi: 10.1002/psc.1347

Structure, dynamics, and energetics of siRNA-cationic vector complexation: A molecular dynamics study

Ouyang, D. F., Zhang, H., Herten, D. P., Parekh, H. S. and Smith, S. C. (2010). Structure, dynamics, and energetics of siRNA-cationic vector complexation: A molecular dynamics study. Journal of Physical Chemistry B, 114 (28), 9220-9230. doi: 10.1021/jp911906e

Structure and dynamics of multiple cationic vectors-siRNA complexation by all-atomic molecular dynamics simulations

Ouyang, Defang, Zhang, Hong, Parekh, Harendra S. and Smith, Sean C. (2010). Structure and dynamics of multiple cationic vectors-siRNA complexation by all-atomic molecular dynamics simulations. Journal of Physical Chemistry B, 114 (28), 9231-9237. doi: 10.1021/jp911913c

Dendrosome-based delivery of siRNA against E6 and E7 oncogenes in cervical cancer

Dutta, Tathagata, Burgess, Melinda, McMillan, Nigel A. J. and Parekh, Harendra S. (2010). Dendrosome-based delivery of siRNA against E6 and E7 oncogenes in cervical cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 6 (3), 463-470. doi: 10.1016/j.nano.2009.12.001

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039

Flexibility of short-strand RNA in aqueous solution as revealed by molecular dynamics simulation: Are A-RNA and A'-RNA distinct conformational structures?

Ouyang, Defang, Zhang, Hong, Herten, Dirk-Peter, Parekh, Harendra S. and Smith, Sean C (2009). Flexibility of short-strand RNA in aqueous solution as revealed by molecular dynamics simulation: Are A-RNA and A'-RNA distinct conformational structures?. Australian Journal of Chemistry, 62 (9), 1054-1061. doi: 10.1071/CH09090

A new dawn for the use of traditional Chinese medicine in cancer therapy

Parekh, Harendra S., Liu, Gang and Wei, Ming Q. (2009). A new dawn for the use of traditional Chinese medicine in cancer therapy. Molecular Cancer, 8 (1) 21, 21.1-21.8. doi: 10.1186/1476-4598-8-21

A combined approach of chemical enhancers and sonophoresis for the transdermal delivery of tizanidine hydrochloride

Mutalik, S., Parekh, H., Davies, N. M. and Udupa, Nayanabhirama (2009). A combined approach of chemical enhancers and sonophoresis for the transdermal delivery of tizanidine hydrochloride. Drug Delivery, 16 (2), 82-91. doi: 10.1080/10717540802605053

Reducible disulfide-based non-viral gene delivery systems

Ouyang, D., Shah, N., Zhang, H, Smith, S. C. and Parekh, H. S. (2009). Reducible disulfide-based non-viral gene delivery systems. Mini-Reviews in Medicinal Chemistry, 9 (10), 1242-1250. doi: 10.2174/138955709789055225

The advance of dendrimers - A versatile targeting platform for gene/drug delivery

Parekh, H. S. (2007). The advance of dendrimers - A versatile targeting platform for gene/drug delivery. Current Pharmaceutical Design, 13 (27), 2837-2850. doi: 10.2174/138161207781757024

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

Parekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029

A Dde-based carboxy linker for solid-phase synthesis

Chhabra, S. R., Parekh, H., Khan, A., Bycroft, B. and Kellam, B. (2001). A Dde-based carboxy linker for solid-phase synthesis. Tetrahedron Letters, 42 (11), 2189-2192. doi: 10.1016/S0040-4039(01)00101-0

Thermosensitive nanoemulsion-based Sol-Gel of Clozapine for nose-to-brain delivery

Tan, Madeleine S.A., Pandey, Preeti, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Thermosensitive nanoemulsion-based Sol-Gel of Clozapine for nose-to-brain delivery. Micro and Nanoparticles in Drug and Vaccine Delivery Symposium, Brisbane, QLD Australia, 3 December 2021.

Nanoemulsion-based sol-gel of Clozapine for nose-to-brain delivery

Tan, Madeleine S. A., Pandey, Preeti, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Nanoemulsion-based sol-gel of Clozapine for nose-to-brain delivery. Drug Delivery Australia Virtual Meeting: Advanced Materials in Drug Delivery, Online, 18 - 19 November 2021.

Shell properties of a new acoustofluidic delivery agent

AL-Sadiq, H. A., Tupally, K. R., Parekh, H S. and M Veidt, M. (2021). Shell properties of a new acoustofluidic delivery agent. EPSM 2020, Engineering and Physical Sciences in Medicine, Brisbane, QLD Australia, 28-29 October 2020. Dordrecht, Netherlands: Springer Netherlands.

Thermosensitive Micellar Hydrogels of Clozapine for Nose-to-Brain Delivery

Tan, Madeleine SA, Pandey, Preeti, Balmanno, Alexandra, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Thermosensitive Micellar Hydrogels of Clozapine for Nose-to-Brain Delivery. 2021 CRS Virtual Annual Meeting, Mount Laurel, NJ United States, 25-29 July 2021 .

Can monitoring clozapine and norclozapine levels reduce the occurrence of peripheral ADRs?

Tan, Madeleine S. A., Honarparvar, Faraz , Falconer, James R., Parekh, Harendra S., Pandey, Preeti and Siskind, Dan J. (2020). Can monitoring clozapine and norclozapine levels reduce the occurrence of peripheral ADRs?. ASCEPT-APSA Joint Virtual Scientific Meeting, Hamilton Central, QLD, Australia, 24-26 November 2020.

Therapeutic drug monitoring as a tool for clozapine therapy in minimising peripheral ADRs

Tan, Madeleine , Honarparvar, Faraz , Falconer, James , Parekh, Harendra , Pandey, Preeti and Siskind, Dan (2020). Therapeutic drug monitoring as a tool for clozapine therapy in minimising peripheral ADRs. Australian Society for Medical Research (ASMR) Queensland Post Graduate Students Virtual Scientific Symposium, Sydney, NSW Australia, 10-11 November 2020.

Development and optimization of clozapine-loaded PLGA nanoparticles for nose-to-brain delivery using supercritical fluid technology

Tan, Madeleine S. A. , Parekh, Harendra S., Pandey, Preeti , Siskind, Dan J. and Falconer, James R. (2020). Development and optimization of clozapine-loaded PLGA nanoparticles for nose-to-brain delivery using supercritical fluid technology. 7th FIP Pharmaceutical Sciences World Congress, The Hague, Netherlands, 4-6 October 2020.

Concentration stability of monolayer and bilayer lipid microbubbles–a precursor for new drug delivery applications

Alsadiq, H., Tupally, K. R., Kokil, G. R., Vogel, R., Parekh, H. S. and Veidt, M. (2019). Concentration stability of monolayer and bilayer lipid microbubbles–a precursor for new drug delivery applications. Drug Delivery Australia 2019 Conference, Brisbane, QLD Australia, 18-19 November 2019.

Influence of acoustofluidic parameters on velocity streaming of sonicated medical microbubbles

Alsadiq, Hussain, Reddy, Karnaker, Parekh, Harendra and Veidt, Martin (2018). Influence of acoustofluidic parameters on velocity streaming of sonicated medical microbubbles. AAS2018: Acoustics 2018: Hear to Listen, Adelaide, SA Australia, 6-9 November 2018. Adelaide, SA Australia: Australian Acoustical Society.

Development and validation of RP-HPLC method for quantification of peptide dendrimers in skin permeation experiments

Mutalik, Srinivas, Parekh, Harendra S., Hewavitharana, Amitha K., Shaw, P. Nick, Anissimov, Yuri G. and Roberts, Michael S. (2008). Development and validation of RP-HPLC method for quantification of peptide dendrimers in skin permeation experiments. Australian Pharmaceutical Science Association Conference 2008, Canberra, ACT Australia, 6-9 December 2008.