Dr Patrick Harris

NHMRC Early Career Fellow

UQ Centre for Clinical Research
Faculty of Medicine
+61 7 334 65476


Dr Patrick Harris is an Infectious Disease Physician, Medical Microbiologist and NHMRC Early Career Fellow at The University of Queensland Centre for Clinical Research (UQCCR).

Dr. Harris obtained a BSc in Psychology and Anthropology from Durham University, prior to acquiring his medical degree from University College London Medical School. Following postgraduate training in the UK, he worked as a clinical lecturer at the College of Medicine in Malawi, before completing specialist training in infectious diseases and microbiology in Australia. For his final year of training he was a Senior Visiting Fellow in Infectious Disease at the National University Hospital in Singapore. He completed his PhD in 2018 under the supervision of Prof. David Paterson, with a focus on multi-drug resistant Gram-negative bacteria.

Research Interests

  • Clinical trials
    Assessing the clinical impact of novel antibiotic treatment strategies for bloodstream infections
  • Antibiotic resistance
    Resistance in gram-negative pathogens such as E. coli, Klebsiella and Enterobacter

Research Impacts

He has published more than 50 peer-reviewed articles, many as first author, including recent publications in JAMA, the Lancet, Lancet Infectious Diseases and Clinical Infectious Diseases. Since 2013 has been coordinating the MERINO trial: an international multicentre study to compare carbapenem-sparing treatment options for ESBL and AmpC-producing species. This has been the first large RCT to specifically address this question, using a protocol developed and endorsed by the Australasian Society for Infectious Diseases Clinical Research Network (ASID-CRN). https://clinicaltrials.gov/ct2/show/NCT02176122.

Other currently active research projects include:

  1. Pilot Randomised controlled trial of meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to AmpC-producing Enterobacter, Citrobacter, Serratia, Providencia and Morganella (MERINO-2 trial). https://clinicaltrials.gov/ct2/show/NCT02437045
  2. Queensland Genomic Health Alliance (QGHA) Clinical Demonstration Project: Whole genome sequencing to track, treat and prevent nosocomial infections. https://www.qgha.org/project-demonstration-projects/
  3. Using whole-genome sequencing to characterise carbapenem-resistant Enterobacteriaceae from QLD (the CREATE-Q Study), in collaboration with Pathology Queensland and A/Prof Scott Beatson (https://beatsonlab.com)
  4. Susceptibility of Burkholderia pseudomallei to a novel siderophore cephalosporin (cefiderocol)
  5. Assessing the effects of antibiotics on the human gut microbiome of patients admitted to the ICU (with Dr Sanmarie Schelbusch)
  6. Whole-genome sequencing of ESBL-producing E. coli and Klebsiella spp. bloodstream isolates (MERINO Trial), in collaboration with A/Prof Scott Beatson (https://beatsonlab.com)


  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Medicine/Surgery, University of London


View all Publications


  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision


Book Chapter

  • Bennett, Harrison Y., Harris, Patrick N., Holmes, Michael, Grummet, Jeremy and Roberts, Matthew (2018). Prostate biopsy related infection – risk factors, prevention strategies and management approaches. Urogenital infections and inflammations. (pp. 1-30) edited by T.E. Bjerklund Johansen, F. M.E. Wagenlehner, Y.-H. Cho, T. Matsumoto, J. N. Krieger, D. Shoskes and K. Naber. Berlin, Germany: GMS Publishing House. doi: 10.5680/lhuii000040

  • Peleg, A. Y. and Harris, P. (2017). Meropenem / Meropenem-vaborbactam. Kucers' the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. (pp. 697-722) edited by Lindsay Grayson. Boca Raton, FL United States: Taylor & Francis. doi: 10.1201/9781315152110

Journal Article

Conference Publication

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Note for students: Dr Patrick Harris is not currently available to take on new students.

Current Supervision