The University of Queensland

Oral drug delivery for modified release formulations

Edmund S. Kostewicz, Maria Vertzoni, Heather A. E. Benson and Michael S. Roberts eds. (2022). Oral drug delivery for modified release formulations. Hoboken, NJ, United States: John Wiley and Sons Inc.. doi: 10.1002/9781119772729

Drug delivery approaches: perspectives from pharmacokinetics and pharmacodynamics

Berner, Bret, Gordi, Toufigh, Benson, Heather A. E. and Roberts, Michael S. (2021). Drug delivery approaches: perspectives from pharmacokinetics and pharmacodynamics. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119772767

Fundamentals of Drug Delivery

Benson, Heather A. E., Roberts, Michael S., Williams, Adrian C. and Liang, Xiaowen eds. (2021). Fundamentals of Drug Delivery. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/9781119769644

Dermal absorption and toxicity assessment: Second edition

Roberts, Michael S. and Walters, Kenneth A. (2007). Dermal absorption and toxicity assessment: Second edition. CRC Press.

Dermatologic, cosmeceutic, and cosmetic development: Therapeutic and novel approaches

Walters, Kenneth A. and Roberts, Michael S. (2007). Dermatologic, cosmeceutic, and cosmetic development: Therapeutic and novel approaches. CRC Press.

Final report on the evaluation of the Quality Care Pharmacy Program

Chapman, John, Roberts, Michael and Stokes, Julie (2005). Final report on the evaluation of the Quality Care Pharmacy Program. Canberra A.C.T., Australia: Pharmacy Guild of Australia.

Challenges and innovations of controlled drug delivery

Benson, Heather A.E. and Roberts, Michael S. (2022). Challenges and innovations of controlled drug delivery. Fundamentals of Drug Delivery. (pp. 3-14) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119769644.ch1

Theranostic nanoparticles for imaging and targeted drug delivery to the liver

Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12

Revealing interaction of dyes and nanomaterials by multiphoton imaging

Holmes, Amy, Thorling, Camilla, Liu, Xin, Liang, Xiaowen, Wang, Haolu, Breunig, Hans G., König, Karsten, Studier, Hauke and Roberts, Michael S. (2018). Revealing interaction of dyes and nanomaterials by multiphoton imaging. Multiphoton microscopy and fluorescence lifetime imaging: applications in biology and medicine. (pp. 345-368) edited by Karsten König. Berlin, Germany: Walter de Gruyter. doi: 10.1515/9783110429985-020

Efficacy, safety and targets in topical and transdermal active and excipient delivery

Mohammed, Yousuf H., Moghimi, Hamid R., Yousef, Shereen A., Chandrasekaran, Navin C., Bibi, Césa R., Sukumar, Sinduja C., Grice, Jeffrey E., Sakran, Wedad and Roberts, Michael S. (2017). Efficacy, safety and targets in topical and transdermal active and excipient delivery. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 369-391) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer . doi: 10.1007/978-3-662-53270-6_23

Hepatic metabolism in liver health and disease

Liu, X., Wang, H., Liang, X. and Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. Liver Pathophysiology: Therapies and Antioxidants. (pp. 391-400) edited by Pablo Muriel. Cambridge, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-804274-8.00030-8

Non-formulation parameters that affect penetrant-skin-vehicle interactions and percutaneous absorption

Grice, Jeffrey E., Moghimi, Hamid R., Ryan, Elizabeth, Zhang, Qian, Haridass, Isha, Mohammed, Yousuf and Roberts, Michael S. (2017). Non-formulation parameters that affect penetrant-skin-vehicle interactions and percutaneous absorption. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 45-75) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer . doi: 10.1007/978-3-662-53270-6_4

Related topic: Safety evaluation of nanomaterials

Liang, Xiaowen, Wang, Haolu, Liu, Xin, Grice, Jeffrey, Xu, Zhi Ping and Roberts, Michael S. (2017). Related topic: Safety evaluation of nanomaterials. Skin permeation and disposition of therapeutic and cosmeceutical compounds. (pp. 313-322) edited by Kenji Sugibayashi. Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-56526-0_28

Selection of topically applied chemical candidates: transdermal drug delivery systems

Pastore, Michael N. and Roberts, Michael S. (2017). Selection of topically applied chemical candidates: transdermal drug delivery systems. Skin permeation and disposition of therapeutic and cosmeceutical compounds. (pp. 251-262) edited by Kenji Sugibayashi. Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-56526-0_21

Skin penetration

Machado, A. C. H. R., Lopes, P. S., Raffier, C. P., Haridass, I. N., Roberts, M., Grice, J. and Leite-Silva, V. R. (2017). Skin penetration. Cosmetic Science and Technology: Theoretical Principles and Applications. (pp. 741-755) edited by KAZUTAMI SAKAMOTO, ROBERT Y. LOCHHEAD, HOWARD I. MAIBACH and YUJI YAMASHITA. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-802005-0.00046-X

The influence of emollients on dermal and transdermal drug delivery

Leite-Silva, V. R., Grice, Jeffrey E., Mohammed, Yousuf, Moghimi, Hamid R. and Roberts, Michael S. (2017). The influence of emollients on dermal and transdermal drug delivery. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 77-93) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer. doi: 10.1007/978-3-662-53270-6_5

Formulation effects on topical nanoparticle penetration

Benson, H. A. E., Mohammed, Y., Grice, J. E. and Roberts, M. S. (2016). Formulation effects on topical nanoparticle penetration. Nanoscience in dermatology. (pp. 115-126) edited by Michael R. Hamblin, Pinar Avci and Tarl W. Prow. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-802926-8.00009-4

Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver

Thorling, Camilla A., Holmes, Amy, Studier, Hauke, Liu, David, Liang, Xiaowen and Roberts, Michael S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. (pp. 107-123) edited by Stefan G. Stanciu. Rijeka, Croatia: InTech. doi: 10.5772/63452

Formulation effects in percutaneous absorption

Kuswahyuning, Rina, Grice, Jeffrey E., Moghimi, Hamid R. and Roberts, Michael S. (2015). Formulation effects in percutaneous absorption. Percutaneous penetration enhancers chemical methods in penetration enhancement : drug manipulation strategies and vehicle effects. (pp. 109-134) edited by Nina Dragicevic and Howard I. Maibach. Berlin / Heidelberg, Germany: Springer. doi: 10.1007/978-3-662-45013-0_9

Fluorescence lifetime imaging for diagnostic and therapeutic intravital microscopy

Sanchez, Washington Y., Song, Zhen, Becker, Wolfgang, Koenig, Karsten and Roberts, Michael S. (2014). Fluorescence lifetime imaging for diagnostic and therapeutic intravital microscopy. Advances in intravital microscopy: from basic to clinical research. (pp. 371-418) edited by Roberto Weigert. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-017-9361-2_16

Mathematical models for topical and transdermal drug products

Anissimov, Yuri G. and Roberts, Michael S. (2014). Mathematical models for topical and transdermal drug products. Topical drug bioavailability, bioequivalence, and penetration. (pp. 249-298) edited by Vinod P. Shah, Howard I. Maibach and John Jenner. New York, NY, United States: Springer. doi: 10.1007/978-1-4939-1289-6_15

Electrical and physical methods of skin penetration enhancement

Grice, Jeffrey E., Prow, Tarl W., Kendall, Mark A. F. and Roberts, Michael S. (2012). Electrical and physical methods of skin penetration enhancement. Topical and transdermal drug delivery: Principles and practice. (pp. 43-65) edited by Heather A. E. Benson and Adam C. Watkinson. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781118140505.ch3

Changes in skin immunity with age and disease

Geusens, Barbara, Mollet, Ilse, Anderson, Chris D., Terras, Sarah, Roberts, Michael S. and Lambert, Jo (2011). Changes in skin immunity with age and disease. Innate immune system of skin and oral mucosa: properties and impact in pharmaceutics, cosmetics, and personal care products. (pp. 217-258) edited by Nava Dayan and Philip W. Wertz. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781118025338.ch11

Introduction to dermatokinetics

Wu, Ya-Ting, Anissimov, Yuri G. and Roberts, Michael S. (2011). Introduction to dermatokinetics. Dermatokinetics of therapeutic agents. (pp. 1-23) edited by S. Narasimha Murthy. Boca Raton, FL, United States: CRC Press.

Chemical structure-skin transport relationships

Grice, Jeffrey E., Zhang, Qian and Roberts, Michael S. (2010). Chemical structure-skin transport relationships. Toxicology of the skin. (pp. 55-68) edited by Nancy A. Monteiro-Riviere. New York , NY, U.S.A.: Informa Healthcare USA. doi: 10.3109/9781420079180

Cutaneous metabolism and active transport in transdermal drug delivery

Dancik, Yuri, Thompson, Camilla, Krishnan, Gayathri and Roberts, Michael S. (2010). Cutaneous metabolism and active transport in transdermal drug delivery. Toxicology of the skin. (pp. 69-82) edited by Nancy A. Monteiro-Riviere, A. Wallace Hayes, John A. Thomas and Donald E. Gardner. New York , NY, U.S.A.: Informa Healthcare USA.

Optimizing drug dosing in the ICU

Kruger, P., Liu, X. and Roberts, M. S. (2009). Optimizing drug dosing in the ICU. Optimizing Drug Dosing in the ICU. (pp. 859-869) edited by Vincent, JL. Berlin, Germany: Springer. doi: 10.1007/978-3-540-92276-6

Beyond stratum corneum

Dancik, Yuri, Jepps, Owen G. and Roberts, Michael S. (2008). Beyond stratum corneum. Dermal absorption and toxicity assessment. (pp. 209-250) edited by Michael S. Roberts and Kenneth A. Walters. New York, USA: Informa Healthcare.

Drugs for Pain and Inflammation

Whitehouse, M., Sarkar, M. and Roberts, M.S. (2008). Drugs for Pain and Inflammation. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 215-241) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.

Human Skin Morphology and Dermal Absorption

Roberts, M.S. and Walters, K.A. (2008). Human Skin Morphology and Dermal Absorption. Dermal Absorption and Toxicity Assessment. (pp. 1-16) edited by Roberts, M.S. and Walters, K.A.. USA: Informa Healthcare.

Iontophoresis

Kanikkannan, N., Bonner, M., Singh, J. and Roberts, M.S. (2008). Iontophoresis. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 517-535) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.

Physiologically based pharmacokinetics and pharmacodynamics of skin

Dancik, Y., Jepps, O. and Roberts, M. S. (2008). Physiologically based pharmacokinetics and pharmacodynamics of skin. Dermal Absorption and Toxicity Assessment. (pp. 179-207) edited by Michael S. Roberts and Kenneth A. Walters. USA: Informa Healthcare.

Regulating modified-release drug delivery technologies in Australia

Bartholomaeus, Andrew, Rolls, Carolyn and Roberts, Michael S. (2008). Regulating modified-release drug delivery technologies in Australia. Modified-Release Drug Delivery Technology, Second Edition. (pp. 473-485) CRC Press.

Regulatory aspects in modified-release drug delivery

Roberts, Michael S., Bartholomaeus, Andrew, Wade, George, Ghani, Sultan and Marroum, Patrick J. (2008). Regulatory aspects in modified-release drug delivery. Modified-Release Drug Delivery Technology, Second Edition. (pp. 357-383) CRC Press.

Skin Hydration - A Key Determinant in Topical Absorption

Roberts, M.S., Bouwstra, J., Pirot, F. and Falson, F. (2008). Skin Hydration - A Key Determinant in Topical Absorption. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 115-128) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.

Skin Structure, Pharmaceuticals, Cosmetics, and the Efficacy of Topically Applied Agents

Roberts, M.S. and Walters, K.A. (2008). Skin Structure, Pharmaceuticals, Cosmetics, and the Efficacy of Topically Applied Agents. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 1-10) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.

Solvent and Vehicle Effects on the Skin

Roberts, M.S., Gierden, A., Riviere, Jim E and Monteiro-Riviere, Nancy. A (2008). Solvent and Vehicle Effects on the Skin. Dermal Absorption and Toxicity Assessment. (pp. 433-447) edited by Roberts, M.S. and Walters, K.A.. USA: Informa Healthcare.

Drugs for pain and inflammation

Whitehouse, Michael W., Sarkar, Mantu and Roberts, Michael S. (2007). Drugs for pain and inflammation. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 215-242) CRC Press.

Iontophoresis

Kanikkannan, Narayanasamy, Bonner, Michael, Singh, Jagdish and Roberts, Michael S. (2007). Iontophoresis. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 517-536) CRC Press.

Physiologically based pharmacokinetics and pharmacodynamics of skin

Dancik, Yuri, Jepps, Owen G. and Roberts, Michael S. (2007). Physiologically based pharmacokinetics and pharmacodynamics of skin. Dermal Absorption and Toxicity Assessment, Second Edition. (pp. 179-208) CRC Press.

Skin hydration-a key determinant in topical absorption

Roberts, Michael S., Bouwstra, Joke, Pirot, Fabrice and Falson, Françoise (2007). Skin hydration-a key determinant in topical absorption. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 115-124) CRC Press.

Skin structure, pharmaceuticals, cosmetics, and the efficacy of topically applied agents

Walters, Kenneth A. and Roberts, Michael S. (2007). Skin structure, pharmaceuticals, cosmetics, and the efficacy of topically applied agents. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 1-11) CRC Press.

Solvent and vehicle effects on the skin

Roberts, Michael S., Gierden, Audrey, Riviere, Jim E. and Monteiro-Riviere, Nancy A. (2007). Solvent and vehicle effects on the skin. Dermal Absorption and Toxicity Assessment, Second Edition. (pp. 433-448) CRC Press.

Dermal blood flow, lymphatics, and binding as determinants of topical absorption, clearance and distribution

Cross, Sheree and Roberts, Michael (2006). Dermal blood flow, lymphatics, and binding as determinants of topical absorption, clearance and distribution. Dermal Absorption Models in Toxicology and Pharmacology. (pp. 251-281) edited by Jim Edmond Riviere. Boca Raton Florida, USA: Taylor & Francis.

Mathematical models in peercutaneous absorption

Roberts, M. S. and Anissimov, Y. (2005). Mathematical models in peercutaneous absorption. Percutaneous Absorption. (pp. 1-44) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.

Percutaneous absorption of sunscreens

Walters, K. and Roberts, M. S. (2005). Percutaneous absorption of sunscreens. Percutaneous Absorption. (pp. 681-700) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.

The skin reservoir for topically applied solutes

Cross, S.E., Anissimov, Y. and Roberts, M. S. (2005). The skin reservoir for topically applied solutes. Percutaneous Absorption. (pp. 213-234) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.

Pharmacokinetics and metabolism of the salicylates

Graham, G. G., Roberts, Michael S., Day, R. O. and Rainsford, K. D. (2004). Pharmacokinetics and metabolism of the salicylates. Aspirin and related drugs. (pp. 97-155) edited by K.D. Rainsford. London, U.K.: Taylor & Francis.

Skin transport

Roberts, Michael S., Elizabeth Cross, Sheree and Pellett, Mark A. (2002). Skin transport. Dermatological and Transdermal Formulations. (pp. 89-196) edited by Kenneth A. Walters.. New York, United States: CRC Press.

The structure and function of skin

Walters, Kenneth A. and Roberts, Michael S. (2002). The structure and function of skin. Dermatological and Transdermal Formulations. (pp. 1-40) edited by Kenneth A. Walters. New York, United States: CRC Press.

Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS

Qiang, Shuping, Mohamed, Fahim, Mackenzie, Lorraine and Roberts, Michael S. (2023). Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS. Talanta, 254 124115, 1-12. doi: 10.1016/j.talanta.2022.124115

Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning

Alinaghi, Azadeh, Zhang, Qian, Williams, Desmond B., Mackenzie, Lorraine and Roberts, Michael S. (2023). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal of Pharmaceutics, 630 122424, 1-10. doi: 10.1016/j.ijpharm.2022.122424

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120

Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing

Liu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095

Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model

Arora, Sumit, Clarke, James, Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffery E., Roberts, Michael S., Jamei, Masoud and Polak, Sebastian (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19 (9), 3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229

Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum

Amarah, A. A., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics, 623 121902, 1-10. doi: 10.1016/j.ijpharm.2022.121902

Advances and future perspectives in epithelial drug delivery

Mohammed, Yousuf, Holmes, Amy, Kwok, Philip Chi Lip, Kumeria, Tushar, Namjoshi, Sarika, Imran, Mohammad, Matteucci, Lana, Ali, Masood, Tai, Waiting, Benson, Heather A.E. and Roberts, Michael S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186 114293, 1-38. doi: 10.1016/j.addr.2022.114293

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242

Multi-modal imaging to assess the follicular delivery of zinc pyrithione

Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076

Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients

Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x

In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics

Rowland, Malcolm, Roberts, Michael S. and Pang, K Sandy (2022). In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics. Drug metabolism and disposition: the biological fate of chemicals, 50 (2), 187-190. doi: 10.1124/dmd.121.000637

Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo

Jung, Nathalie, Namjoshi, Sarika, Mohammed, Yousuf, Grice, Jeffrey E., Benson, Heather A. E., Raney, Sam G., Roberts, Michael S. and Windbergs, Maike (2022). Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo. Pharmaceutical Research, 39 (5), 935-948. doi: 10.1007/s11095-022-03245-7

Predicting viable skin concentration: modelling the subpapillary plexus

Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2022). Predicting viable skin concentration: modelling the subpapillary plexus. Pharmaceutical Research, 39 (4), 783-793. doi: 10.1007/s11095-022-03215-z

Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens

Khabir, Zahra, Holmes, Amy M., Lai, Yi-Jen, Liang, Liuen, Deva, Anand, Polikarpov, Michael A., Roberts, Michael S. and Zvyagin, Andrei V. (2021). Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens. International Journal of Molecular Sciences, 22 (22) 12372, 12372. doi: 10.3390/ijms222212372

Topical drug delivery: history, percutaneous absorption, and product development

Roberts, Michael S., Cheruvu, Hanumanth S., Mangion, Sean E., Alinaghi, Azadeh, Benson, Heather A.E., Mohammed, Yousuf, Holmes, Amy, van der Hoek, John, Pastore, Michael and Grice, Jeffrey E. (2021). Topical drug delivery: history, percutaneous absorption, and product development. Advanced Drug Delivery Reviews, 177 113929, 113929. doi: 10.1016/j.addr.2021.113929

Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling

Al-Qurain, Aymen A., Williams, Desmond B., Mackenzie, Lorraine, Roberts, Michael S. and Wiese, Michael D. (2021). Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling. Journal of Pharmaceutical and Biomedical Analysis, 203 114171, 1-8. doi: 10.1016/j.jpba.2021.114171

Targeted delivery of zinc pyrithione to skin epithelia

Mangion, Sean E., Holmes, Amy M. and Roberts, Michael S. (2021). Targeted delivery of zinc pyrithione to skin epithelia. International Journal of Molecular Sciences, 22 (18) 9730. doi: 10.3390/ijms22189730

Viscoelastic and deformation characteristics of structurally different commercial topical systems

Dabbaghi, Maryam, Namjoshi, Sarika, Panchal, Bhavesh, Grice, Jeffrey E., Prakash, Sangeeta, Roberts, Michael Stephen and Mohammed, Yousuf (2021). Viscoelastic and deformation characteristics of structurally different commercial topical systems. Pharmaceutics, 13 (9) 1351. doi: 10.3390/pharmaceutics13091351

Liver organoid as a 3D in vitro model for drug validation and toxicity assessment

Brooks, Anastasia, Liang, Xiaowen, Zhang, Yonglong, Zhao, Chun-Xia, Roberts, Michael S., Wang, Haolu, Zhang, Lei and Crawford, Darrell H.G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169 105608, 105608. doi: 10.1016/j.phrs.2021.105608

Artificial cells for the treatment of liver diseases

Zou, Da, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S. and Zhao, Chun-Xia (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114. doi: 10.1016/j.actbio.2021.06.012

Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models

Liu, Xin, Anissimov, Yuri G., Grice, Jeffrey E., Cheruvu, Hanumanth Srikanth, Ghosh, Priyanka, Raney, Sam G., Maibach, Howard and Roberts, Michael S. (2021). Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models. Journal of Controlled Release, 334, 37-51. doi: 10.1016/j.jconrel.2021.04.010

Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study

Buckley, Nicholas A., Fahim, Mohamed, Raubenheimer, Jacques, Gawarammana, Indika B., Eddleston, Michael, Roberts, Michael S. and Dawson, Andrew H. (2021). Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study. The Lancet Global Health, 9 (6), e854-e862. doi: 10.1016/S2214-109X(21)00086-3

Efficacy and safety of statins in ethnic differences: A lesson for application in Indigenous Australian patient care

Gebremichael, Lemlem G., Suppiah, Vijayaprakash, Wiese, Michael D., Mackenzie, Lorraine, Phillips, Craig, Williams, Desmond B. and Roberts, Michael S. (2021). Efficacy and safety of statins in ethnic differences: A lesson for application in Indigenous Australian patient care. Pharmacogenomics, 22 (9), 553-571. doi: 10.2217/pgs-2020-0152

Acute phenthoate self-poisoning: a prospective case series

Rambabu, Lekaashree, Mohamed, Fahim, Dhanarisi, Jeevan, Gawarammana, Indika, Raubenheimer, Jacques, Mackenzie, Lorraine, Roberts, Michael S., Buckley, Nicholas and Eddleston, Michael (2021). Acute phenthoate self-poisoning: a prospective case series. Clinical Toxicology, 60 (2), 1-7. doi: 10.1080/15563650.2021.1917596

Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients

Al-Qurain, Aymen A., Upton, Richard, Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick T., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2021). Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients. European Journal of Clinical Pharmacology, 77 (9), 1357-1368. doi: 10.1007/s00228-021-03126-9

Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia

Al-Qurain, Aymen Ali, Gebremichael, Lemlem G., Khan, Mohammed S., Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick, Roberts, Michael S. and Wiese, Michael D. (2021). Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia. International Journal of Clinical Pharmacy, 43 (2), 365-374. doi: 10.1007/s11096-020-01191-1

Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test

Abd, Eman, Gomes, Juliana, Sales, Caroline Cianga, Yousef, Shereen, Forouz, Farzaneh, Telaprolu, Krishna Chaitanya, Roberts, Michael S., Grice, Jeffrey E., Lopes, Patricia Santos, Leite‐Silva, Vânia R. and Newton, Andréo‐Filho (2021). Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test. International Journal of Cosmetic Science, 43 (1) ics.12659, 1-10. doi: 10.1111/ics.12659

Measurement of Hansen Solubility Parameters of third-degree burn eschar

Hosseini, Maryam, Roberts, Michael S., Aboofazeli, Reza and Moghimi, Hamid R. (2021). Measurement of Hansen Solubility Parameters of third-degree burn eschar. Burns, 48 (4), 860-871. doi: 10.1016/j.burns.2021.07.017

Modeling drug transport within the viable skin - a review

Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2021). Modeling drug transport within the viable skin - a review. Expert Opinion on Drug Metabolism and Toxicology, 17 (1), 105-119. doi: 10.1080/17425255.2020.1832081

Using in vivo multiphoton fluorescence lifetime imaging to unravel disease-specific changes in the liver redox state

Barkauskas, Deborah S., Medley, Gregory, Liang, Xiaowen, Mohammed, Yousuf H., Thorling, Camilla A., Wang, Haolu and Roberts, Michael S. (2020). Using in vivo multiphoton fluorescence lifetime imaging to unravel disease-specific changes in the liver redox state. Methods and Applications in Fluorescence, 8 (3) 034003, 034003. doi: 10.1088/2050-6120/ab93de

Penetration of Zinc into Human Skin after Topical Application of Nano Zinc Oxide Used in Commercial Sunscreen Formulations

Holmes, Amy M., Kempson, Ivan, Turnbull, Tyron, Paterson, David and Roberts, Michael S. (2020). Penetration of Zinc into Human Skin after Topical Application of Nano Zinc Oxide Used in Commercial Sunscreen Formulations. ACS Applied Bio Materials, 3 (6), 3640-3647. doi: 10.1021/acsabm.0c00280

Measurement of hansen solubility parameters of human stratum corneum

Ezati, Negin, Roberts, Michael Stephen, Zhang, Qian and Moghimi, Hamid Reza (2020). Measurement of hansen solubility parameters of human stratum corneum. Iranian Journal of Pharmaceutical Research, 19 (3), 572-578. doi: 10.22037/ijpr.2019.112435.13755

Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose

Liu, Xin, Yousef, Shereen, Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose. European Journal of Pharmaceutics and Biopharmaceutics, 149, 30-44. doi: 10.1016/j.ejpb.2020.01.018

Quality by design: development of the quality target product profile (QTPP) for semisolid topical products

Namjoshi, Sarika, Dabbaghi, Maryam, Roberts, Michael S., Grice, Jeffrey E. and Mohammed, Yousuf (2020). Quality by design: development of the quality target product profile (QTPP) for semisolid topical products. Pharmaceutics, 12 (3) 287, 287. doi: 10.3390/pharmaceutics12030287

Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients

Al-Qurain, Aymen Ali, Gebremichael, Lemlem G., Khan, Muhammad Suleman, Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick, Roberts, Michael S. and Wiese, Michael D. (2020). Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients. Drugs and Aging, 37 (4), 291-300. doi: 10.1007/s40266-019-00742-0

Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma

Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun-Xia, Crawford, Darrell H. G., Roberts, Michael S. and Liang, Xiaowen (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147 (6) ijc.32899, 1519-1527. doi: 10.1002/ijc.32899

Novel nanocarriers for targeted topical skin delivery of the antioxidant resveratrol

Nastiti, Christofori M. R. R., Ponto, Thellie, Mohammed, Yousuf, Roberts, Michael S. and Benson, Heather A. E. (2020). Novel nanocarriers for targeted topical skin delivery of the antioxidant resveratrol. Pharmaceutics, 12 (2) 108, 108. doi: 10.3390/pharmaceutics12020108

Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis

Holmes, Amy M., Mackenzie, Lorraine and Roberts, Michael S. (2020). Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis. Nanotoxicology, 14 (2), 263-274. doi: 10.1080/17435390.2019.1692382

Noninvasive in vivo human multiphoton microscopy: a key method in proving nanoparticulate zinc oxide sunscreen safety

Mohammed, Yousuf, Barkauskas, Deborah, Holmes, Amy, Grice, Jeffrey and Roberts, Michael (2020). Noninvasive in vivo human multiphoton microscopy: a key method in proving nanoparticulate zinc oxide sunscreen safety. Journal of Biomedical Optics, 25 (1) 014509, 014509-014509. doi: 10.1117/1.JBO.25.1.014509

Bathing does not facilitate human skin penetration or adverse cellular effects of nanoparticulate zinc oxide sunscreens after topical application

Mohammed, Yousuf H., Haridass, Isha N., Grice, Jeffrey E., Benson, Heather A.E. and Roberts, Michael S. (2020). Bathing does not facilitate human skin penetration or adverse cellular effects of nanoparticulate zinc oxide sunscreens after topical application. Journal of Investigative Dermatology, 140 (8), 1656-1659. doi: 10.1016/j.jid.2019.12.024

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900

Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent

Isoardi, K. Z., Page, C. B., Roberts, M. S. and Isbister, G. K. (2020). Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent. Clinical Toxicology, 59 (1), 1-4. doi: 10.1080/15563650.2020.1757103

Modeling percutaneous absorption for successful drug discovery and development

Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Modeling percutaneous absorption for successful drug discovery and development. Expert Opinion on Drug Discovery, 15 (10), 1-18. doi: 10.1080/17460441.2020.1781085

Mechanistic evaluation of enhanced curcumin delivery through human skin in vitro from optimised nanoemulsion formulations fabricated with different penetration enhancers

Yousef, Shereen A., Mohammed, Yousuf H., Namjoshi, Sarika, Grice, Jeffrey E., Benson, Heather A. E., Sakran, Wedad and Roberts, Michael S. (2019). Mechanistic evaluation of enhanced curcumin delivery through human skin in vitro from optimised nanoemulsion formulations fabricated with different penetration enhancers. Pharmaceutics, 11 (12) 639, 639. doi: 10.3390/pharmaceutics11120639

Targeted topical delivery of retinoids in the management of acne vulgaris: Current formulations and novel delivery systems

Latter, Gemma, Grice, Jeffrey E., Mohammed, Yousuf, Roberts, Michael S. and Benson, Heather A. E. (2019). Targeted topical delivery of retinoids in the management of acne vulgaris: Current formulations and novel delivery systems. Pharmaceutics, 11 (10) 490, 490. doi: 10.3390/pharmaceutics11100490

Cellular metabolism and pore lifetime of human skin following microprojection array mediation

Haridass, Isha N., Wei, Jonathan C. J., Mohammed, Yousuf H., Crichton, Michael L., Anderson, Christopher D., Henricson, Joakim, Sanchez, Washington Y., Meliga, Stefano C., Grice, Jeffrey E., Benson, Heather A. E., Kendall, Mark A. F. and Roberts, Michael S. (2019). Cellular metabolism and pore lifetime of human skin following microprojection array mediation. Journal of Controlled Release, 306, 59-68. doi: 10.1016/j.jconrel.2019.05.024

Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster

Rainsford, K. D., Roberts, Michael S., Nencioni, Alessandro and Jones, Clarence (2019). Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster. Current Medical Research and Opinion, 35 (6), 989-1002. doi: 10.1080/03007995.2018.1551194

Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application

Nastiti, Christofori M.R.R., Mohammed, Yousuf, Telaprolu, Krishna C., Liang, Xiaowen, Grice, Jeffrey E., Roberts, Michael S. and Benson, Heather A.E. (2019). Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application. Skin Pharmacology and Physiology, 32 (4), 1-10. doi: 10.1159/000499435

Permeation mechanism of caffeine and naproxen through in vitro human epidermis: Effect of vehicles and penetration enhancers

Abd, Eman, Benson, Heather A.E., Mohammed, Yousuf H., Roberts, Michael S. and Grice, Jeffrey E. (2019). Permeation mechanism of caffeine and naproxen through in vitro human epidermis: Effect of vehicles and penetration enhancers. Skin Pharmacology and Physiology, 32 (3), 132-141. doi: 10.1159/000497225

Optical characterisation of zinc pyrithione

Sandiford, Lydia , Holmes, Amy M. , Mangion, Sean E. , Mohammed, Yousuf H. , Zvyagin, Andrei V. and Roberts, Michael S. (2019). Optical characterisation of zinc pyrithione. Photochemistry and Photobiology, 95 (5) php.13100, 1142-1150. doi: 10.1111/php.13100

Stimulus-responsive antibiotic releasing systems for the treatment of wound infections

Schultz, Hayley B., Vasani, Roshan B., Holmes, Amy M., Roberts, Michael S. and Voelcker, Nicolas H. (2019). Stimulus-responsive antibiotic releasing systems for the treatment of wound infections. ACS Applied Bio Materials, 2 (2), 704-716. doi: 10.1021/acsabm.8b00577

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers

Mohammed, Yousuf H., Holmes, Amy, Haridass, Isha N., Sanchez, Washington Y., Studier, Hauke, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2019). Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers. Journal of Investigative Dermatology, 139 (2), 308-315. doi: 10.1016/j.jid.2018.08.024

Topical and transdermal drug delivery: from simple potions to smart technologies

Benson, Heather A. E., Grice, Jeffrey E., Mohammed, Yousuf, Namjoshi, Sarika and Roberts, Michael S. (2019). Topical and transdermal drug delivery: from simple potions to smart technologies. Current Drug Delivery, 16 (5), 444-460. doi: 10.2174/1567201816666190201143457

Designer artificial membrane binding proteins to direct stem cells to the myocardium

Xiao, Wenjin, Green, Thomas I. P., Liang, Xiaowen, Delint, Rosalia Cuahtecontzi, Perry, Guillaume, Roberts, Michael S., Le Vay, Kristian, Back, Catherine R., Ascione, Raimomdo, Wang, Haolu, Race, Paul R. and Perriman, Adam W. (2019). Designer artificial membrane binding proteins to direct stem cells to the myocardium. Chemical Science, 10 (32), 7610-7618. doi: 10.1039/c9sc02650a

Impact of age on risk of lymph node positivity in patients with colon cancer

Wang, Haolu, Lu, Hao, Yang, Haotian, Zhang, Xianwen, Thompson, Erik W., Roberts, Michael S., Hu, Zhigian, Liang, Xiaowen and Li, Xinxing (2019). Impact of age on risk of lymph node positivity in patients with colon cancer. Journal of Cancer, 10 (9), 2102-2108. doi: 10.7150/jca.28377

ZnO:SBA-15 Nanocomposites for potential use in sunscreen: Preparation, properties, human skin penetration and toxicity

Vieira, Camila O., Grice, Jeffrey E., Roberts, Michael S., Haridass, Isha N., Duque, Marcelo Dutra, Lopes, Patrícia S., Leite-Silva, Vânia R. and Martins, Tereza S. (2019). ZnO:SBA-15 Nanocomposites for potential use in sunscreen: Preparation, properties, human skin penetration and toxicity. Skin Pharmacology and Physiology, 32 (1), 32-42. doi: 10.1159/000491758

Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays

Wei, Jonathan C. J., Haridass, Isha N., Crichton, Michael L., Mohammed, Yousuf H., Meliga, Stefano C., Sanchez, Washington Y., Grice, Jeffrey E., Benson, Heather A. E., Roberts, Michael S. and Kendall, Mark A. F. (2018). Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays. Scientific Reports, 8 (1) 17759, 1-15. doi: 10.1038/s41598-018-36009-8

Anionic long-circulating quantum dots for long-term intravital vascular imaging

Wang, Haolu, Yang, Haotian, Xu, Zhi Ping, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018). Anionic long-circulating quantum dots for long-term intravital vascular imaging. Pharmaceutics, 10 (4) 244, 244. doi: 10.3390/pharmaceutics10040244

The antioxidant activity of recombinant rat hepatic fatty acid binding protein t94a variant

Le, Tyson, Gong, Yuewen, Wang, Guqi, Davies, Neal M., Lillico, Ryan, Lakowski, Ted, Roberts, Michael S. and Burczynski, Frank J (2018). The antioxidant activity of recombinant rat hepatic fatty acid binding protein t94a variant. Journal of Pharmacy and Pharmaceutical Sciences, 21 (1S), 309s-324s. doi: 10.18433/jpps30246

The role of cellular reactive oxygen species in cancer chemotherapy

Yang, Haotian, Villani, Rehan M., Wang, Haolu, Simpson, Matthew J., Roberts, Michael S., Tang, Min and Liang, Xiaowen (2018). The role of cellular reactive oxygen species in cancer chemotherapy. Journal of Experimental and Clinical Cancer Research, 37 (1) 266, 266. doi: 10.1186/s13046-018-0909-x

Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers

Yamada, Miko, Tayeb, Hossam, Wang, Hequn, Dang, Nhung, Mohammed, Yousuf H., Osseiran, Sam, Belt, Paul J., Roberts, Michael S., Evans, Conor L., Sainsbury, Frank and Prow, Tarl W. (2018). Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers. Journal of Controlled Release, 288, 264-276. doi: 10.1016/j.jconrel.2018.09.012

Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography

Alahakoon, Chanika, Dassanayake, Tharaka L., Gawarammana, Indika B., Sedgwick, E. Michael, Weerasinghe, Vajira S., Abdalla, Ahmed, Roberts, Michael S. and Buckley, Nicholas A. (2018). Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography. PLoS ONE, 13 (9) e0203596, e0203596. doi: 10.1371/journal.pone.0203596

Compartmental modeling of skin transport

Amarah, A. A., Petlin, D. G., Grice, J. E., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2018). Compartmental modeling of skin transport. European Journal of Pharmaceutics and Biopharmaceutics, 130, 336-344. doi: 10.1016/j.ejpb.2018.07.015

Follicular penetration of caffeine from topically applied nanoemulsion formulations containing penetration enhancers: in vitro human skin studies

Abd, Eman, Benson, Heather A. E., Roberts, Michael S. and Grice, Jeffrey E. (2018). Follicular penetration of caffeine from topically applied nanoemulsion formulations containing penetration enhancers: in vitro human skin studies. Skin Pharmacology and Physiology, 31 (5), 252-260. doi: 10.1159/000489857

Removing physiological motion from intravital and clinical functional imaging data

Warren, Sean C., Nobis, Max, Magenau, Astrid, Mohammed, Yousuf H., Herrmann, David, Moran, Imogen, Vennin, Claire, Conway, James R. W., Mélénec, Pauline, Cox, Thomas R., Wang, Yingxiao, Morton, Jennifer P., Welch, Heidi C. E., Strathdee, Douglas, Anderson, Kurt I., Phan, Tri Giang, Roberts, Michael S. and Timpson, Paul (2018). Removing physiological motion from intravital and clinical functional imaging data. eLife, 7 e35800. doi: 10.7554/eLife.35800

Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial

Morley, Kirsten C., Baillie, Andrew, Fraser, Isabel, Furneaux-Bate, Ainsley, Dore, Glenys, Roberts, Michael, Abdalla, Ahmed, Nghi Phung, and Haber, Paul S. (2018). Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial. British Journal of Psychiatry, 212 (6), 362-369. doi: 10.1192/bjp.2018.13

Alternative methods to animal studies for the evaluation of topical/transdermal drug delivery systems

Garcia, Maria Teresa Junqueira, Vasconcelos, Fabia Leal Lopes, Raffier, Chloe Patricia, Roberts, Michael Stephen, Grice, Jeffrey Ernest, Benson, Heather Ann Elizabeth and Leite-Silva, Vania Rodrigues (2018). Alternative methods to animal studies for the evaluation of topical/transdermal drug delivery systems. Current Topics in Medicinal Chemistry, 18 (4), 287-299. doi: 10.2174/1568026618666180412153214

Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin

Holmes, Amy M., Kempson, Ivan, Turnbull, Tyron, Paterson, David and Roberts, Michael S. (2018). Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin. Toxicology and Applied Pharmacology, 343, 40-47. doi: 10.1016/j.taap.2018.02.012

"Massive" metformin overdose

Chiew, Angela L., Wright, Daniel F. B., Dobos, Nicola M., McArdle, Kylie, Mostafa, Ahmed A., Newth, Annemarie, Roberts, Michael S. and Isbister, Geoffrey K. (2018). "Massive" metformin overdose. British Journal of Clinical Pharmacology, 84 (12), 2923-2927. doi: 10.1111/bcp.13582

Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057

Using a simple equation to predict the microporation-enhanced transdermal drug flux

Rzhevskiy, Alexey S., Telaprolu, Krishna, Mohammed, Yousuf H., Grice, Jeffrey E., Roberts, Michael S. and Anissimov, Yuri G. (2018). Using a simple equation to predict the microporation-enhanced transdermal drug flux. European Journal of Pharmaceutics and Biopharmaceutics, 127, 12-18. doi: 10.1016/j.ejpb.2018.01.019

Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination

Chan, Betty S. H., Chiew, Angela L., Grainger, Sarah, Page, Colin B., Gault, Alan, Mostafa, Ahmed, Roberts, Michael S., Buckley, Nicholas A. and Isbister, Geoffrey K. (2018). Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination. Clinical Toxicology, 56 (9), 1-3. doi: 10.1080/15563650.2018.1433299

Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

Abd, Eman, Benson, Heather A. E., Roberts, Michael S. and Grice, Jeffrey E. (2018). Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting. Pharmaceutics, 10 (1) 19, 1-12. doi: 10.3390/pharmaceutics10010019

Development and Evaluation of Lipid Nanoparticles Containing Natural Botanical Oil for Sun Protection: Characterization and in vitro and in vivo Human Skin Permeation and Toxicity

Andréo-Filho, Newton, Bim, Antonio Vinicius Kosiski, Kaneko, Telma Mary, Kitice, Nidia Ayumi, Haridass, Isha N., Abd, Eman, Santos Lopes, Patricia, Thakur, Sachin S., Parekh, Harendra S., Roberts, Michael S., Grice, Jeffrey E., Benson, Heather A.E. and Leite-Silva, Vânia Rodrigues (2018). Development and Evaluation of Lipid Nanoparticles Containing Natural Botanical Oil for Sun Protection: Characterization and in vitro and in vivo Human Skin Permeation and Toxicity. Skin Pharmacology and Physiology, 31 (1), 1-9. doi: 10.1159/000481691

Indocyanine green-incorporating nanoparticles for cancer theranostics

Wang, Haolu, Li, Xinxing, Tse, Brian Wan-Chi, Yang, Haotian, Thorling, Camilla A., Liu, Yuxin, Touraud, Margaux, Chouane, Jean Batiste, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018). Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, 8 (5), 1227-1242. doi: 10.7150/thno.22872

Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice

Jin, Wang, Liang, Xiaowen, Brooks, Anastasia, Futrega, Kathryn, Liu, Xin, Doran, Michael R., Simpson, Matthew J., Roberts, Michael S. and Wang, Haolu (2018). Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice. PeerJ, 2018 (12) e6072, e6072. doi: 10.7717/peerj.6072

Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’

Chiew, Angela L., Wright, Daniel F. B., Roberts, Michael S. and Isbister, Geoffrey K. (2018). Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’. British Journal of Clinical Pharmacology, 84 (12), 2940-2941. doi: 10.1111/bcp.13747

Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells

Brooks, Anastasia, Futrega, Kathryn, Liang, Xiaowen, Hu, Xiaoling, Liu, Xin, Crawford, Darrell H. G., Doran, Michael R., Roberts, Michael S. and Wang, Haolu (2017). Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Translational Medicine, 7 (1), 78-86. doi: 10.1002/sctm.17-0209

Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells

Wang, Haolu, Thorling, Camilla A., Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells. Current Protocols in Stem Cell Biology, 43 (1), 1-17. doi: 10.1002/cpsc.39

Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome

Chan, Betty S., Becker, Therese, Chiew, Angela L., Abdalla, Ahmed M., Robertson, Tom A., Liu, Xin, Roberts, Michael S. and Buckley, Nicholas A. (2017). Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome. Journal of Medical Toxicology, 14 (1), 100-103. doi: 10.1007/s13181-017-0637-1

Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia

Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17

2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion

Chiew, Angela L., Page, Colin B., Clancy, David, Mostafa, Ahmed, Roberts, Michael S. and Isbister, Geoffrey K. (2017). 2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion. Clinical Toxicology, 56 (5), 377-380. doi: 10.1080/15563650.2017.1385790

An audit of medicines information quality in electronically generated discharge summaries – evidence to meet the Australian national safety and quality health service standards

Gilbert, Alice V., Patel, Bhavini K., Roberts, Michael S., Williams, Desmond B., Crofton, Jackie H., Morris, Nicola M., Wallace, Joanna and Gilbert, Andrew L. (2017). An audit of medicines information quality in electronically generated discharge summaries – evidence to meet the Australian national safety and quality health service standards. Journal of Pharmacy Practice and Research, 47 (5), 355-364. doi: 10.1002/jppr.1256

Topical nano and microemulsions for skin delivery

Nastiti, Christofori M. R. R., Ponto, Thellie, Abd, Eman, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2017). Topical nano and microemulsions for skin delivery. Pharmaceutics, 9 (4) 37, 1-25. doi: 10.3390/pharmaceutics9040037

Pramipexole Overdose Associated with Visual Hallucinations, Agitation and Myoclonus

Cardon-Dunbar, Adeline, Robertson, Tom, Roberts, Michael S. and Isbister, Geoffrey K. (2017). Pramipexole Overdose Associated with Visual Hallucinations, Agitation and Myoclonus. Journal of Medical Toxicology, 13 (4), 343-346. doi: 10.1007/s13181-017-0615-7

Multiphoton imaging for assessing renal disposition in acute kidney injury

Liu, Xin, Liang, Xiaowen, Wang, Haolu, Roberts, Darren M. and Roberts, Michael S. (2017). Multiphoton imaging for assessing renal disposition in acute kidney injury. SPIE Biophotonics Australasia, 10013. doi: 10.1117/12.2242964

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374, 45374. doi: 10.1038/srep45374

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Topical and cutaneous delivery using nanosystems

Roberts, M. S., Mohammed, Y., Pastore, M. N., Namjoshi, S., Yousef, S., Alinaghi, A., Haridass, I. N., Abd, E., Leite-Silva, V. R., Benson, H. A. E. and Grice, J. E. (2017). Topical and cutaneous delivery using nanosystems. Journal of Controlled Release, 247, 86-105. doi: 10.1016/j.jconrel.2016.12.022

Warfarin poisoning with delayed rebound toxicity

Berling, Ingrid, Mostafa, Ahmed, Grice, Jeffrey E., Roberts, Michael S. and Isbister, Geoffrey K. (2017). Warfarin poisoning with delayed rebound toxicity. Journal of Emergency Medicine, 52 (2), 194-196. doi: 10.1016/j.jemermed.2016.05.068

Non-invasive metabolic imaging of melanoma progression

Pastore, Michael N., Studier, Hauke, Bonder, Claudine S. and Roberts, Michael S. (2017). Non-invasive metabolic imaging of melanoma progression. Experimental Dermatology, 26 (7), 607-614. doi: 10.1111/exd.13274

Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16

Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations

Jayaweera, Dushan, Islam, Shawkat, Gunja, Naren, Cowie, Chris, Broska, James, Poojara, Latesh, Roberts, Michael S. and Isbister, Geoffrey K. (2016). Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations. Clinical Toxicology, 55 (2), 1-4. doi: 10.1080/15563650.2016.1249795

Skin models for the testing of transdermal drugs

Abd, Eman, Yousef , Shereen A., Pastore, Michael N., Telaprolu, Krishna, Mohammed, Yousuf H., Namjoshi, Sarika, Grice, Jeffrey E. and Roberts, Michael S. (2016). Skin models for the testing of transdermal drugs. Clinical Pharmacology: Advances and Applications, 8, 163-176. doi: 10.2147/CPAA.S64788

Varying the morphology of silver nanoparticles results in differential toxicity against micro-organisms, HaCaT keratinocytes and affects skin deposition

Holmes, Amy M., Lim, Julian, Studier, Hauke and Roberts, Michael S. (2016). Varying the morphology of silver nanoparticles results in differential toxicity against micro-organisms, HaCaT keratinocytes and affects skin deposition. Nanotoxicology, 10 (10), 1-12. doi: 10.1080/17435390.2016.1236993

Mechanistic evaluation of hydration effects on the human epidermal permeation of salicylate esters

Yousef, Shereen, Mohammed, Yousuf, Namjoshi, Sarika, Grice, Jeffrey, Sakran, Wedad and Roberts, Michael (2016). Mechanistic evaluation of hydration effects on the human epidermal permeation of salicylate esters. AAPS Journal, 19 (1), 1-11. doi: 10.1208/s12248-016-9984-0

Estimating maximal in vitro skin permeation flux from studies using non-sink receptor phase conditions

Yousef, Shereen, Liu, Xin, Mostafa, Ahmed, Mohammed, Yousuf, Grice, Jeffrey E., Anissimov, Yuri G., Sakran, Wedad and Roberts, Michael S. (2016). Estimating maximal in vitro skin permeation flux from studies using non-sink receptor phase conditions. Pharmaceutical Research, 33 (9), 2180-2194. doi: 10.1007/s11095-016-1955-8

High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka – implications for global suicide prevention

Lamb, Thomas, Selvarajah, Liza R., Mohamed, Fahim, Jayamanne, Shaluka, Gawarammana, Indika, Mostafa, Ahmed, Buckley, Nicholas A., Roberts, Michael S. and Eddleston, Michael (2016). High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka – implications for global suicide prevention. Clinical Toxicology, 54 (8), 624-631. doi: 10.1080/15563650.2016.1187735

Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4577-4584. doi: 10.1128/AAC.00531-16

Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment

Leite-Silva, V. R., Sanchez, W. Y., Studier, H., Liu, D. C., Mohammed, Y. H., Holmes, A. M., Ryan, E. M., Haridass, I. N., Chandrasekaran, N. C., Becker, W., Grice, J. E., Benson, H. A. E. and Roberts, M. S. (2016). Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment. European Journal of Pharmaceutics and Biopharmaceutics, 104 (4), 140-147. doi: 10.1016/j.ejpb.2016.04.022

Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy

Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2016). Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of Biophotonics, 10 (1), 46-60. doi: 10.1002/jbio.201600083

Permeation of topically applied magnesium ions through human skin is facilitated by hair follicles

Chandrasekaran, Navin Chandrakanth, Sanchez, Washington Y., Mohammed, Yousuf H., Grice, Jeffrey E., Roberts, Michael S. and Barnard, Ross T. (2016). Permeation of topically applied magnesium ions through human skin is facilitated by hair follicles. Magnesium Research, 29 (2), 35-42. doi: 10.1684/mrh.2016.0402

Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles

Leite-Silva, Vania R., Liu, David C., Sanchez, Washington Y., Studier, Hauke, Mohammed, Yousuf H., Holmes, Amy, Becker, Wolfgang, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2016). Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles. Nanomedicine, 11 (10), 1193-1205. doi: 10.2217/nnm-2016-0010

SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells

Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 (1) 22293, e22293.1-e22293.12. doi: 10.1038/srep22293

Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations

Holmes, Amy M., Song, Zhen, Moghimi, Hamid R. and Roberts, Michael S. (2016). Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations. ACS Nano, 10 (2), 1810-1819. doi: 10.1021/acsnano.5b04148

Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles

Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 (2), 939-945. doi: 10.1021/acs.nanolett.5b03854

Cardiovascular toxicity with levetiracetam overdose

Page, Colin B., Mostafa, Ahmed, Saiao, Ana, Grice, Jeffrey E., Roberts, Michael S. and Isbister, Geoffrey K. (2016). Cardiovascular toxicity with levetiracetam overdose. Clinical Toxicology, 54 (2), 152-154. doi: 10.3109/15563650.2015.1115054

In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15

Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney

Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016). Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 (1), 387-395. doi: 10.1021/acsnano.5b05066

Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen

Abd, Eman, Namjoshi, Sarika, Mohammed, Yousuf H., Roberts, Michael S. and Grice, Jeffrey E. (2016). Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen. Journal of Pharmaceutical Sciences, 105 (1), 212-220. doi: 10.1002/jps.24699

Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock

Isbister, Geoffrey K., Ang, Karyn, Gorman, Kieron, Cooper, Joyce, Mostafa, Ahmed and Roberts, Michael S. (2016). Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock. Clinical Toxicology, 54 (9), 881-885. doi: 10.1080/15563650.2016.1209768

A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations

Abd, Eman, Roberts, Michael S. and Grice, Jeffrey E. (2015). A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations. Skin Pharmacology and Physiology, 29 (1), 24-30. doi: 10.1159/000441040

Optimization of dosing regimens and dosing in special populations

Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 (10), 886-893. doi: 10.1016/j.cmi.2015.05.002

Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies

Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 (9), 5463-5469. doi: 10.1128/AAC.00389-15

Acute behavioural disturbance associated with phenibut purchased via an internet supplier

Downes, Michael A., Berling, Ingrid L., Mostafa, Ahmed, Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Acute behavioural disturbance associated with phenibut purchased via an internet supplier. Clinical Toxicology, 53 (7), 636-638. doi: 10.3109/15563650.2015.1059945

The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose

Michael, Adam P., Mostafa, Ahmed, Cooper, Joyce M., Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose. Clinical Toxicology, 53 (7), 633-635. doi: 10.3109/15563650.2015.1054504

Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017

2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death

Berling, Ingrid, Buckley, Nicholas A., Mostafa, Ahmed, Downes, Michael A., Grice, Jeffrey, Medley, Gregory, Roberts, Michael S. and Isbister, Geoffrey K. (2015). 2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death. Clinical Toxicology, 53 (5), 486-488. doi: 10.3109/15563650.2015.1030025

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 (8) dkv123, 2369-2375. doi: 10.1093/jac/dkv123

Transdermal patches: History, development and pharmacology

Pastore, Michael N, Kalia, Yogeshvar N, Horstmann, Michael and Roberts, Michael S (2015). Transdermal patches: History, development and pharmacology. British Journal of Pharmacology, 172 (9), 2179-2209. doi: 10.1111/bph.13059

Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury

Arab, Hossein-Ali, Walker, Neal I., Cheung, Kee, Hickman, Peter E., Potter, Jolia M., Kadkhodaee, Mehri and Roberts, Michael S. (2015). Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury. Journal of Investigative Surgery, 28 (2), 77-85. doi: 10.3109/08941939.2014.971205

Using deconvolution to understand the mechanism for variable plasma concentration-time profiles after intramuscular injection

Mahmood, Adnan H., Liu, Xin, Grice, Jeffrey E., Medley, Gregory A. and Roberts, Michael S. (2015). Using deconvolution to understand the mechanism for variable plasma concentration-time profiles after intramuscular injection. International Journal of Pharmaceutics, 481 (1-2), 71-78. doi: 10.1016/j.ijpharm.2015.01.046

A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics

Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8

Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging

Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780

Diagnostic imaging and therapeutic application of nanoparticles targeting the liver

Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 (6), 939-958. doi: 10.1039/C4TB01611D

Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y

Feasibility of a Patient-Centered Deprescribing Process to Reduce Inappropriate Use of Proton Pump Inhibitors

Reeve E., Andrews J.M., Wiese M.D., Hendrix I., Roberts M.S. and Shakib S. (2015). Feasibility of a Patient-Centered Deprescribing Process to Reduce Inappropriate Use of Proton Pump Inhibitors. Annals of Pharmacotherapy, 49 (1), 29-38. doi: 10.1177/1060028014558290

Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition

Thorling C.A., Jin L., Weiss M., Crawford D., Liu X., Burczynski F.J., Liu D., Wang H. and Roberts M.S. (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug Metabolism and Disposition, 43 (1), 154-162. doi: 10.1124/dmd.114.060848

Isoniazid poisoning: Pharmacokinetics and effect of hemodialysis in a massive ingestion

Skinner, Kirsty, Saiao, Ana, Mostafa, Ahmed, Soderstrom, Jessamine, Medley, Gregory, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Isoniazid poisoning: Pharmacokinetics and effect of hemodialysis in a massive ingestion. Hemodialysis International, 19 (4), E37-E40. doi: 10.1111/hdi.12293

Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology

Gordon, Sarah, Daneshian, Mardas, Bouwstra, Joke, Caloni, Francesca, Constant, Samuel, Davies, Donna E., Dandekar, Gudrun, Guzman, Carlos A., Fabian, Eric, Haltner, Eleonore, Hartung, Thomas, Hasiwa, Nina, Hayden, Patrick, Kandarova, Helena, Khare, Sangeeta, Krug, Harald F., Kneuer, Carsten, Leist, Marcel, Lian, Guoping, Marx, Uwe, Metzger, Marco, Ott, Katharina, Prieto, Pilar, Roberts, Michael S., Roggen, Erwin L., Tralau, Tewes, van den Braak, Claudia, Walles, Heike and Lehr, Claus-Michael (2015). Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology. Altex-Alternatives to Animal Experimentation, 32 (4), 327-378. doi: 10.14573/altex.1510051

Microprojection arrays to immunise at mucosal surfaces

McNeilly, Celia L., Crichton, Michael L., Primiero, Clare A., Frazer, Ian H., Roberts, Michael S. and Kendall, Mark A. F. (2014). Microprojection arrays to immunise at mucosal surfaces. Journal of Controlled Release, 196, 252-260. doi: 10.1016/j.jconrel.2014.09.028

Using skin for drug delivery and diagnosis in the critically ill

Liu, Xin, Kruger, Peter, Maibach, Howard, Colditz, Paul B. and Roberts, Michael S. (2014). Using skin for drug delivery and diagnosis in the critically ill. Advanced Drug Delivery Reviews, 77, 40-49. doi: 10.1016/j.addr.2014.10.004

The benefits and harms of deprescribing

Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2014). The benefits and harms of deprescribing. Medical Journal of Australia, 201 (7), 386-389. doi: 10.5694/mja13.00200

Prediction of paraquat exposure and toxicity in clinically ill poisoned patients: a model based approach

Wunnapuk, Klintean, Mohammed, Fahim, Gawarammana, Indika, Liu, Xin, Verbeeck, Roger K., Buckley, Nicholas A., Roberts, Michael S. and Musuamba, Flora T. (2014). Prediction of paraquat exposure and toxicity in clinically ill poisoned patients: a model based approach. British Journal of Clinical Pharmacology, 78 (4), 855-866. doi: 10.1111/bcp.12389

Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process

Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2014). Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process. British Journal of Clinical Pharmacology, 78 (4), 738-747. doi: 10.1111/bcp.12386

Multiphoton microscopy in defining liver function

Thorling, Camilla A., Crawford, Darrell, Burczynski, Frank J., Liu, Xin, Liau, Ian and Roberts, Michael S. (2014). Multiphoton microscopy in defining liver function. Journal of Biomedical Optics, 19 (9) 090901, 90901-090901. doi: 10.1117/1.JBO.19.9.090901

Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin

Mohammed, Yousuf H., Yamada, Miko, Lin, Lynlee L., Grice, Jeffrey E., Roberts, Michael S., Raphael, Anthony P., Benson, Heather A. E. and Prow, Tarl W. (2014). Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin. PLoS One, 9 (7) e101956, e101956.1-e101956.9. doi: 10.1371/journal.pone.0101956

Effects of magnesium deficiency - More than skin deep

Chandrasekaran, Navin Chandrakanth, Weir, Christopher, Alfraji, Sumaya, Grice, Jeff, Roberts, Michael S. and Barnard, Ross T. (2014). Effects of magnesium deficiency - More than skin deep. Experimental Biology and Medicine, 239 (10), 1280-1291. doi: 10.1177/1535370214537745

Concentration dependency in nicotine skin penetration flux from aqueous solutions reflects vehicle induced changes in nicotine stratum corneum retention

Kuswahyuning, Rina and Roberts, Michael S. (2014). Concentration dependency in nicotine skin penetration flux from aqueous solutions reflects vehicle induced changes in nicotine stratum corneum retention. Pharmaceutical Research, 31 (6), 1501-1511. doi: 10.1007/s11095-013-1256-4

Iontophoretic skin permeation of peptides: an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters

Krishnan, Gayathri, Roberts, Michael S., Grice, Jeffrey, Anissimov, Yuri G., Moghimi, Hamid R. and Benson, Heather A. E. (2014). Iontophoretic skin permeation of peptides: an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters. Drug Delivery and Translational Research, 4 (3), 222-232. doi: 10.1007/s13346-013-0181-8

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523

Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats

Thorling, Camilla A., Roberts, Michael S., Liu, Xin, Fletcher, Linda M., Crawford, Darrell and Burczynski, Frank J. (2014). Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats. Journal of Pharmacy and Pharmaceutical Sciences, 17 (1), 121-135. doi: 10.18433/J33C7B

Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance

Wunnapuk, Klintean, Liu, Xin, Gobe, Glenda C., Endre, Zoltan H., Peake, Philip W., Grice, Jeffrey E., Roberts, Michael S. and Buckley, Nicholas A. (2014). Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance. Toxicology Letters, 225 (3), 467-478. doi: 10.1016/j.toxlet.2014.01.018

Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers

Wunnapuk, Klintean, Gobe, Glenda, Endre, Zoltan, Peake, Philip, Grice, Jeffrey E., Roberts, Michael S., Buckley, Nicholas A. and Liu, Xin (2014). Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers. Toxicology Letters, 225 (1), 192-200. doi: 10.1016/j.toxlet.2013.12.009

Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy

Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 (6), 3533-3537. doi: 10.1128/AAC.02340-14

Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells

Liang X., Grice J.E., Zhu Y., Liu D., Sanchez W.Y., Li Z., Crawford D.H.G., Le Couteur D.G., Cogger V.C., Liu X., Xu Z.P. and Roberts M.S. (2014). Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells. Small, 11 (14), 1711-1720. doi: 10.1002/smll.201402698

Patient barriers to and enablers of deprescribing: a systematic review

Reeve, Emily, To, Josephine, Hendrix, Ivanka, Shakib, Sepehr, Roberts, Michael S. and Wiese, Michael D. (2013). Patient barriers to and enablers of deprescribing: a systematic review. Drugs and Aging, 30 (10), 793-807. doi: 10.1007/s40266-013-0106-8

Penetration of Nanoparticles into Human Skin

Liang, Xiao Wen, Xu, Zhi Ping, Grice, Jeffrey, Zvyagin, Andrei V., Roberts, Michael S. and Liu, Xin (2013). Penetration of Nanoparticles into Human Skin. Current Pharmaceutical Design, 19 (35), 6353-6366. doi: 10.2174/1381612811319350011

Renal biomarkers predict nephrotoxicity after paraquat

Wunnapuk, Klintean, Liu, Xin, Peake, Philip, Gobe, Glenda, Endre, Zoltan, Grice, Jeffrey E., Roberts, Michael S. and Buckley, Nicholas A. (2013). Renal biomarkers predict nephrotoxicity after paraquat. Toxicology Letters, 222 (3), 280-288. doi: 10.1016/j.toxlet.2013.08.003

People's attitudes, beliefs, and experiences regarding polypharmacy and willingness to deprescribe

Reeve, Emily, Wiese, Michael D., Hendrix, Ivanka, Roberts, Michael S. and Shakib, Sepeh (2013). People's attitudes, beliefs, and experiences regarding polypharmacy and willingness to deprescribe. Journal of the American Geriatrics Society, 61 (9), 1508-1514. doi: 10.1111/jgs.12418

Functional characterization of hepatic transporters using intravital microscopy

Weiss, Michael, Liu, Xin, Thorling, Camilla A. and Roberts, Michael S. (2013). Functional characterization of hepatic transporters using intravital microscopy. European Journal of Pharmaceutical Sciences, 49 (5), 845-849. doi: 10.1016/j.ejps.2013.06.006

Feasibility of multiphoton microscopy-based quantification of antibiotic uptake into neutrophil granulocytes

Mahmood, Adnan, Grice, Jeffrey E., Roberts, Michael S. and Prow, Tarl W. (2013). Feasibility of multiphoton microscopy-based quantification of antibiotic uptake into neutrophil granulocytes. Journal of Biomedical Optics, 18 (7) 076003, 076003.1-076003.6. doi: 10.1117/1.JBO.18.7.076003

Background free imaging of upconversion nanoparticle distribution in human skin

Song, Zhen, Anissimov, Yuri G., Zhao, Jiangbo, Nechaev, Andrei V., Nadort, Annemarie, Jin, Dayong, Prow, Tarl W., Roberts, Michael S. and Zvyagin, Andrei V. (2013). Background free imaging of upconversion nanoparticle distribution in human skin. Journal of Biomedical Optics, 18 (6) 61215, 061215.1-061215.10. doi: 10.1117/1.JBO.18.6.061215

Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging

Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2013). Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging. Journal of Biomedical Optics, 18 (6) 69802, 61217.1-61217.12. doi: 10.1117/1.JBO.18.6.061217

The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo

Leite-Silva, Vania R., Le Lamer, Marina, Sanchez, Washington Y., Liu, David C., Sanchez, Washington H., Morrow, Isabel, Martin, Darren, Silva, Heron D. T., Prow, Tan L. W., Grice, Jeffrey E. and Roberts, Michael S. (2013). The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 84 (2), 297-308. doi: 10.1016/j.ejpb.2013.01.020

A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis

Kruger, Peter, Bailey, Michael, Bellomo, Rinaldo, Cooper, David James, Harward, Meg, Higgins, Alisa, Howe, Belinda, Jones, Darryl, Joyce, Chris, Kostner, Karam, McNeil, John, Nichol, Alistair, Roberts, Michael S., Syres, Gillian, Venkatesh, Bala and ANZ-STATInS Investigators–ANZICS Clinical Trials Group (2013). A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis. American Journal of Respiratory and Critical Care Medicine, 187 (7), 743-750. doi: 10.1164/rccm.201209-1718OC

The development of models for the evaluation of pulmonary drug disposition

Liu, Xin, Jin, Lu, Upham, John W. and Roberts, Michael S. (2013). The development of models for the evaluation of pulmonary drug disposition. Expert Opinion On Drug Metabolism & Toxicology, 9 (4), 487-505. doi: 10.1517/17425255.2013.754009

Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentation in vivo

Dancik, Yuri, Favre, Amandine, Loy, Chong Jin, Zvyagin, Andrei V. and Roberts, Michael S. (2013). Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentation in vivo. Journal of Biomedical Optics, 18 (2) 026022, 26022-026022. doi: 10.1117/1.JBO.18.2.026022

Development and validation of the patients' attitudes towards deprescribing (PATD) questionnaire

Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2013). Development and validation of the patients' attitudes towards deprescribing (PATD) questionnaire. International Journal of Clinical Pharmacy, 35 (1), 51-56. doi: 10.1007/s11096-012-9704-5

Enhanced sonophoretic delivery of 5-aminolevulinic acid: preliminary human ex vivo permeation data

Krishnan, Gayathri, Grice, Jeffrey E., Roberts, Michael S., Benson, Heather A. E. and Prow, Tarl W. (2013). Enhanced sonophoretic delivery of 5-aminolevulinic acid: preliminary human ex vivo permeation data. Skin Research and Technology, 19 (1), e283-e289. doi: 10.1111/j.1600-0846.2012.00640.x

Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes

Anissimov, Yuri G., Jepps, Owen G., Dancik, Yuri and Roberts, Michael S. (2013). Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes. Advanced Drug Delivery Reviews, 65 (2), 169-190. doi: 10.1016/j.addr.2012.04.009

Modeling the human skin barrier - towards a better understanding of dermal absorption

Jepps, Owen G., Dancik, Yuri, Anissimov, Yuri G. and Roberts, Michael S. (2013). Modeling the human skin barrier - towards a better understanding of dermal absorption. Advanced Drug Delivery Reviews, 65 (2), 152-168. doi: 10.1016/j.addr.2012.04.003

A comparison of hepatic ischemia/hypoxia-reperfusion injury models

Arab, Hossein-Ali, Cheung, Kee, Hickman, Peter E., Potter, Julia M., Walker, Neal I. and Roberts, Michael S. (2013). A comparison of hepatic ischemia/hypoxia-reperfusion injury models. Journal of Pharmacological and Toxicological Methods, 68 (3), 349-356. doi: 10.1016/j.vascn.2013.03.002

Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds

Zhang, Qian, Li, Peng, Liu, David and Roberts, Michael S. (2013). Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds. Pharmaceutical Research, 30 (1), 32-40. doi: 10.1007/s11095-012-0846-x

Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury

Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Roberts, Michael S. and Sanchez, Washington Y. (2013). Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury. Journal of Biomedical Optics, 18 (10) 101306, 1-12. doi: 10.1117/1.JBO.18.10.101306

Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis

Mutalik, S., Parekh, H. S., Anissimov, Y. G., Grice, J. E. and Roberts, M. S. (2013). Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis. Skin Pharmacology and Physiology, 26 (3), 127-138. doi: 10.1159/000348469

Solute-vehicle-skin interactions in percutaneous absorption: the principles and the people

Roberts, M. S. (2013). Solute-vehicle-skin interactions in percutaneous absorption: the principles and the people. Skin Pharmacology and Physiology, 26 (4-6), 356-370. doi: 10.1159/000353647

Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (vol 18, 061217, 2013)

Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2012). Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (vol 18, 061217, 2013). Journal of Biomedical Optics, 18 (6) 69802, 069802-069802. doi: 10.1117/1.JBO.18.6.069802

Providing community-based health practitioners with timely and accurate discharge medicines information

Gilbert, Alice V., Patel, Bhavini, Morrow, Melanie, Williams, Desmond, Roberts, Michael S. and Gilbert, Andrew L. (2012). Providing community-based health practitioners with timely and accurate discharge medicines information. BMC Health Services Research, 12 (1) 453, 453.1-453.7. doi: 10.1186/1472-6963-12-453

Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery

Wiechers, J. W., Watkinson, A. C., Cross, S. E. and Roberts, M. S. (2012). Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery. International Journal of Cosmetic Science, 34 (6), 525-535. doi: 10.1111/ics.12001

Erratum: Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (J. Biomed. Opt. (2013) 18 (061217))

Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2012). Erratum: Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (J. Biomed. Opt. (2013) 18 (061217)). Journal of Biomedical Optics, 17 (12) 129801 doi: 10.1117/1.JBO.17.12.129801

Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from Tracer Dilution Data Using a Fractal Model

Weiss, Michael, Li, Peng and Roberts, Michael S. (2012). Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from Tracer Dilution Data Using a Fractal Model. Microcirculation, 19 (8), 723-728. doi: 10.1111/j.1549-8719.2012.00208.x

Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum

Anissimov, Yuri G., Zhao, Xin, Roberts, Michael S. and Zvyagin, Andrei V. (2012). Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum. International Journal of Pharmaceutics, 435 (1), 93-97. doi: 10.1016/j.ijpharm.2012.01.055

Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na+/K+ ATPase digoxin binding

Li, Peng, Weiss, Michael and Roberts, Michael S. (2012). Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na+/K+ ATPase digoxin binding. European Journal of Pharmaceutical Sciences, 47 (2), 506-511. doi: 10.1016/j.ejps.2012.07.008

Delivery of drugs applied topically to the skin

Leite-Silva, Vania Rodrigues, de Almeida, Mariana Mandelli, Fradin, Aurelie, Grice, Jeffrey Ernest and Roberts, Michael Stephen (2012). Delivery of drugs applied topically to the skin. Expert Review of Dermatology, 7 (4), 383-397. doi: 10.1586/edm.12.32

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35

Evaluation of medication-related problems in medication reviews: a comparative perspective

Kaur, Sukhpreet, Roberts, Jason A. and Roberts, Michael S. (2012). Evaluation of medication-related problems in medication reviews: a comparative perspective. Annals of Pharmacotherapy, 46 (7-8), 972-982. doi: 10.1345/aph.1Q694

Intravital multiphoton imaging of rhodamine 123 in the rat liver after intravenous dosing

Liu, Xin, Thorling, Camilla A., Jin, Lu and Roberts, Michael S. (2012). Intravital multiphoton imaging of rhodamine 123 in the rat liver after intravenous dosing. IntraVital, 1 (1), 54-59. doi: 10.4161/intv.21450

Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage

Li, Peng, Robertson, Thomas A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G., Weiss, Michael and Roberts, Michael S. (2012). Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. Pharmaceutical Research, 29 (6), 1658-1669. doi: 10.1007/s11095-012-0690-z

beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 (6), 489-496. doi: 10.1111/j.1440-1681.2012.05715.x

The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis

Liu, Xin, Kruger, Peter S., Weiss, Michael and Roberts, Michael S. (2012). The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. British Journal of Clinical Pharmacology, 73 (5), 741-749. doi: 10.1111/j.1365-2125.2011.04149.x

Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study

Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553

Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application

Dancik, Yuri, Anissimov, Yuri G., Jepps, Owen G. and Roberts, Michael S. (2012). Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application. British Journal of Clinical Pharmacology, 73 (4), 564-578. doi: 10.1111/j.1365-2125.2011.04128.x

Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection

Mahmood, Adnan H., Medley, Gregory A., Grice, Jeffrey E., Liu, Xin and Roberts, Michael S. (2012). Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection. Journal of Pharmaceutical and Biomedical Analysis, 62, 220-223. doi: 10.1016/j.jpba.2012.01.007

Quantum dot penetration into viable human skin

Prow, Tarl W., Monteiro-Riviere, Nancy A., Inman, Alfred O., Grice, Jeffrey E., Chen, Xianfeng, Zhao, Xin, Sanchez, Washington H., Gierden, Audrey, Kendall, Mark A. F., Zvyagin, Andrei V., Erdmann, Detlev, Rivierer, Jim E. and Roberts, Michael S. (2012). Quantum dot penetration into viable human skin. Nanotoxicology, 6 (2), 173-185. doi: 10.3109/17435390.2011.569092

Continuation of Statin Therapy in patients with presumed infection

Kruger, Peter S., Joyce, Christopher J., Harward, Meg L., Jones, Mark A., Kostner, Karam M., Roberts, Michael S. and Venkatesh, Bala (2012). Continuation of Statin Therapy in patients with presumed infection. American Journal of Respiratory and Critical Care Medicine, 185 (4), 456-457. doi: 10.1164/ajrccm.185.4.456a

The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences

Liu, David C., Raphael, Anthony P., Sundh, Daniel, Grice, Jeffrey E., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2012). The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences. Journal of Nanomaterials, 2012 721706, 72176.1-72176.8. doi: 10.1155/2012/721706

Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013

Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport

Song, Zhen, Kelf, Timothy A., Sanchez, Washington H., Roberts, Michael S., Ricka, Jaro, Frenz, Martin and Zvyagin, Andrei V. (2011). Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport. Biomedical Optics Express, 2 (12), 3321-3333. doi: 10.1364/BOE.2.003321

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

Liu, Xin, Grice, Jeff E., Lademann, Juergen, Otberg, Nina, Trauer, Sindy, Patzelt, Alexa and Roberts, Michael S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British Journal of Clinical Pharmacology, 72 (5), 768-774. doi: 10.1111/j.1365-2125.2011.04022.x

Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats

Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Gobe, Glenda C. and Roberts, Michael S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of Biomedical Optics, 16 (11) 116011, 116011-1160118. doi: 10.1117/1.3647597

Pharmacokinetic evaluation of fluconazole in critically ill patients

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11

Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin

Lin, Lynlee L., Grice, Jeffrey E., Butler, Margaret K., Zvyagin, Andrei V., Becker, Wolfgang, Robertson, Thomas A., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2011). Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical Research, 28 (11), 2920-2930. doi: 10.1007/s11095-011-0515-5

Mathematical models of skin permeability: An overview

Mitragotri, Samir, Anissimov, Yuri G., Bunge, Annette L., Frasch, H. Frederick, Guy, Richard H., Hadgraft, Jonathan, Kasting, Gerald B., Lane, Majella E. and Roberts, Michael S. (2011). Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), 115-129. doi: 10.1016/j.ijpharm.2011.02.023

Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

Wunnapuk, Klintean, Medley, Gregory A., Liu, Xin, Grice, Jeffrey E., Jayasinghe, Sudheera, Gawarammana, Indika, Buckley, Nicholas A. and Roberts, Michael S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 879 (28), 3047-3052. doi: 10.1016/j.jchromb.2011.09.008

Modelling dermal drug distribution after topical application in human

Anissimov, Yuri G. and Roberts, Michael Stephen (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical Research, 28 (9), 2119-2129. doi: 10.1007/s11095-011-0437-2

Gold nanoparticle penetration and reduced metabolism in human skin by toluene

Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., Kraus, T., El-Khordagui, L. K., Soyer, H. P., Roberts, M. S., Schneider, M. and Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical Research, 28 (11), 2931-2944. doi: 10.1007/s11095-011-0561-z

Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin

Zhang, Qian, Li, Peng and Roberts, Michael S. (2011). Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin. Journal of Controlled Release, 154 (1), 50-57. doi: 10.1016/j.jconrel.2011.04.018

Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo

Thorling, Camilla A., Dancik, Yuri, Hupple, Clinton W., Medley, Gregory, Liu, Xin, Zvyagin, Andrei V., Robertson, Tom A., Burczynski, Frank J. and Roberts, Michael S. (2011). Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo. Journal of Biomedical Optics, 16 (8) 086013, 086013-1-086013-7. doi: 10.1117/1.3614473

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

Mostafa, Ahmed, Medley, Gregory, Roberts, Darren M., Mohamed, Mosaad Sayed, Elshanawani, Abdalla A., Roberts, Michael S. and Liu, Xin (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 879 (23), 2234-2238. doi: 10.1016/j.jchromb.2011.06.006

Toward a new age of cellular pharmacokinetics in drug discovery

Zhou, Fang, Zhang, Jingwei, Li, Peng, Niu, Fang, Wu, Xiaolan, Wang, Guangji and Roberts, Michael S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug Metabolism Reviews, 43 (3), 335-345. doi: 10.3109/03602532.2011.560607

Changes in antibiotic distribution due to pancreatitis

Fanning, Kent J., Robertson, Thomas A., Prins, Johannes B. and Roberts, Michael S. (2011). Changes in antibiotic distribution due to pancreatitis. Antimicrobial Agents and Chemotherapy, 55 (6), 3008-3011. doi: 10.1128/AAC.00416-10

Nanoparticles and microparticles for skin drug delivery

Prow, Tarl W., Grice, Jeffrey E., Lin, Lynlee L., Faye, Rokhaya, Butler, Margaret, Becker, Wolfgang, Wurm, Elisabeth M. T., Yoong, Corinne, Robertson, Thomas A., Soyer, H. Peter and Roberts, Michael S. (2011). Nanoparticles and microparticles for skin drug delivery. Advanced Drug Delivery Reviews, 63 (6), 470-491. doi: 10.1016/j.addr.2011.01.012

How to measure pharmacokinetics in critically ill patients?

Liu, Xin, Kruger, Peter S. and Roberts, Michael S. (2011). How to measure pharmacokinetics in critically ill patients?. Current Pharmaceutical Biotechnology, 12 (12), 2037-2043. doi: 10.2174/138920111798808239

Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research

König, Karsten, Raphael, Anthony P., Lin, Li, Grice, Jeffrey E., Soyer, H. Peter, Breunig, H. Georg, Roberts, Michael S. and Prow, Tarl W. (2011). Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research. Advanced Drug Delivery Reviews, 63 (4-5), 388-404. doi: 10.1016/j.addr.2011.03.002

Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning

Roberts, Roberts, Darren M., Wilks, Martin F., Roberts, Michael S., Swaminathan, Ramasamyiyer, Mohamed, Fahim, Dawson, Andrew H. and Buckley, Nick A. (2011). Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicology Letters, 202 (1), 69-74. doi: 10.1016/j.toxlet.2011.01.024

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

Li, Peng, Robertson, Thomas A., Thorling, Camilla A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug Metabolism and Disposition, 39 (4), 571-579. doi: 10.1124/dmd.110.036806

Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy

Roberts, Michael S., Dancik, Yuri, Prow, Tarl W., Thorling, Camilla A., Lin, Lynlee L., Grice, Jeffrey E., Robertson, Thomas A., Koenig, Karsten and Becker, Wolfgang (2011). Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (3), 469-488. doi: 10.1016/j.ejpb.2010.12.023

Continuation of statin therapy in patients with presumed infection: A randomized controlled trial

Kruger, Peter S., Harward, Meg L., Jones, Mark A., Joyce, Christopher J., Kostner, Karam M., Roberts, Michael S. and Venkateshm Bala (2011). Continuation of statin therapy in patients with presumed infection: A randomized controlled trial. American Journal of Respiraty and Critical Care Medicine, 183 (6), 774-781. doi: 10.1164/rccm.201006-0955OC

Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients

Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011). Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 (1) 3, 3.1-3.7. doi: 10.1186/1471-2253-11-3

Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution

Davies, Paul G., Venkatesh, Balasubramanian, Morgan, Thomas J., Presneill, Jeffrey J., Kruger, Peter S., Thomas, Bronwyn J., Roberts, Michael S. and Mundy, Julie (2011). Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution. Critical Care, 15 (1) R21, R21-1-R21-8. doi: 10.1186/cc9966

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1. pharmind: Die Pharmazeutische Industrie, 73 (1), 174-177.

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer. pharmind: Die Pharmazeutische Industrie, 73 (2), 376-382.

Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate

Roberts, Michael S., Liu, Xin, Zou, Yuhong, Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda and Crawford, Darrell H. G. (2011). Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate. American Journal of Physiology-gastrointestinal And Liver Physiology, 300 (1), G130-G136. doi: 10.1152/ajpgi.00162.2010

The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 (1) 5, 5.1-5.5. doi: 10.1186/1471-2253-11-5

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin

Geusens, Barbara, Van Gele, Mireille, Braat, Sien, De Smedt, Stefaan C., Stuart, Marc C. A., Prow, Tarl W., Sanchez, Washington, Roberts, Michael S., Sanders, Niek N. and Lambert, Jo (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin. Advanced Functional Materials, 20 (23), 4077-4090. doi: 10.1002/adfm.201000484

Drug structure-transport relationships

Roberts, MS (2010). Drug structure-transport relationships. Journal of Pharmacokinetics And Pharmacodynamics, 37 (6), 541-573. doi: 10.1007/s10928-010-9174-0

Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen)

Green, Bruce, Chandler, Stephen, MacDonald, Garth, Elliott, Geraldine and Roberts, Michael S. (2010). Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen). Journal of Clinical Pharmacology, 50 (12), 1406-1413. doi: 10.1177/0091270009359181

A special issue on skin nanotechnology

Perumal, Omathanu, Michniak-Kohn, Bozena, Touitou, Elka and Roberts, Michael S. (2010). A special issue on skin nanotechnology. Journal of Biomedical Nanotechnology, 6 (5), 405-407. doi: 10.1166/jbn.2010.1142

Are commercially available nanoparticles safe when applied to the skin?

Robertson, Thomas A., Sanchez, Washington Y. and Roberts, Michael S. (2010). Are commercially available nanoparticles safe when applied to the skin?. Journal of Biomedical Nanotechnology, 6 (5), 452-468. doi: 10.1166/jbn.2010.1145

Designing inorganic light-protective skin nanotechnology products

Popov, Alexey P., Zvyagin, Andrei V,, Lademann, Juergen, Roberts, Michael S., Sanchez, Washington, Priezzhev, Alexander V. and Myllyla, Risto (2010). Designing inorganic light-protective skin nanotechnology products. Journal of Biomedical Nanotechnology, 6 (5), 432-451. doi: 10.1166/jbn.2010.1144

Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing

Liu, Xin, Zou, Yuhong, Khlentzos, Alexander M., Yang, Yan, Nikolovski, Julijana, Weiss, Michael and Roberts, Michael S. (2010). Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing. Clinical and Experimental Pharmacology and Physiology, 37 (10), 1028-1033. doi: 10.1111/j.1440-1681.2010.05434.x

Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept

Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 (4), 332-339. doi: 10.1016/j.ijantimicag.2010.06.008

An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: Evidence for two functionally different uptake systems and saturable binding

Weiss, Michael, Li, Peng and Roberts, Michael S. (2010). An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: Evidence for two functionally different uptake systems and saturable binding. Pharmaceutical Research, 27 (9), 1999-2007. doi: 10.1007/s11095-010-0204-9

Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice

Prow, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331

Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy

Sanchez, Washington Y., Prow, Tarl W., Sanchez, Washington H., Grice, Jeffrey E. and Roberts, Michael S. (2010). Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy. Journal of Biomedical Optics, 15 (4) 046008, 046008-1-046008-11. doi: 10.1117/1.3466580

Tracing multiscale mechanisms of drug disposition in normal and diseased livers

Park, Sunwoo, Kim, Sean H. J., Ropella, Glen E. P., Roberts, Michael S. and Hunt, C. Anthony (2010). Tracing multiscale mechanisms of drug disposition in normal and diseased livers. Journal of Pharmacology and Experimental Therapeutics, 334 (1), 124-136. doi: 10.1124/jpet.110.168526

The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration

Grice, Jeffrey E., Cross, Sheree E., Brownlie, Craig and Roberts, Michael S. (2010). The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration. Journal of Pharmacy and Pharmacology, 62 (6), 750-755. doi: 10.1211/jpp.62.06.0011

Cardiac troponin may be released by ischemia alone, without necrosis

Hickman, Peter E., Potter, Julia M., Aroney, Con, Koerbin, Gus, Southcott, Emma, Wu, Alan H. B. and Roberts, Michael S. (2010). Cardiac troponin may be released by ischemia alone, without necrosis. Clinica Chimica Acta, 411 (5-6), 318-323. doi: 10.1016/j.cca.2009.12.009

Acute human self-poisoning with bispyribac-containing herbicide Nominee (R): a prospective observational study

Gawarammana, Indika Bandara, Roberts, Darren M., Mohamed, Fahim, Roberts, Michael S., Medley, Gregory, Jayamanne, Shaluka and Dawson, Andrew (2010). Acute human self-poisoning with bispyribac-containing herbicide Nominee (R): a prospective observational study. Clinical Toxicology, 48 (3), 198-202. doi: 10.3109/15563651003660000

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts

He, S., Liu, X., Yang, Y., Huang, W., Xu, S., Yang, S., Zhang, X. and Roberts, M. S. (2010). Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts. British Journal of Dermatology, 162 (3), 538-546. doi: 10.1111/j.1365-2133.2009.09511.x

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2

Liu, Xin, Yang, Yan, Zhang, Xiaoxiang, Xu, Shengxin, He, Shufang, Huang, Weijuan and Roberts, Michael S. (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2. Journal of Gastroenterology and Hepatology, 25 (2), 420-426. doi: 10.1111/j.1440-1746.2009.05981.x

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008

Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro

Grice, Jeffrey E., Ciotti, Susan, Weiner, Norman, Lockwood, Peter, Cross, Sheree E. and Roberts, Michael S. (2010). Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. Journal of Pharmaceutical Sciences, 99 (2), 712-718. doi: 10.1002/jps.21856

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model

Fernando, Germain J. P., Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Fairmaid, Emily J., Roberts, Michael S., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2010). Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One, 5 (4) e10266, e10266.1-e10266.11. doi: 10.1371/journal.pone.0010266

Skin abrasion: Transdermal delivery, cosmetic and immunological applications

Grice, J. E. and Roberts, M. S. (2010). Skin abrasion: Transdermal delivery, cosmetic and immunological applications. Transdermal, 2 (1), 11-16.

Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2009). Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets. European Journal of Pharmaceutics and Biopharmaceutics, 73 (3), 404-413. doi: 10.1016/j.ejpb.2009.06.012

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039

Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin

Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Jenkins, Derek W.K., Roberts, Michael S., Frazer, Ian H., Fernando, Germain J.P. and Kendall, Mark A.F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of Controlled Release, 139 (3), 212-220. doi: 10.1016/j.jconrel.2009.06.029

Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers

Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08

Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

Xia, C.H., Sun, J.G., Wang, G.J., Shang, L.L., Zhang, X.X., Zhang, R., Peng, Y., Wang, X.J., Hao, H.P., Xie, L. and Roberts, M.S. (2009). Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats. Planta Medica: natural products and medicinal plant research, 76 (3), 245-250. doi: 10.1055/s-0029-1186082

Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver

Fanning, Kent J., Anissimov, Yuri G. and Roberts, Michael S. (2009). Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver. Journal of Pharmaceutical Sciences, 98 (8), 2807-2821. doi: 10.1002/jps.21631

Skin solubility determines maximum transepidermal flux for similar size molecules

Zhang, Qian, Grice, Jeffrey E., Li, Peng, Jepps, Owen G., Wang, Guang-Ji and Roberts, Michael S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26 (8), 1974-1985. doi: 10.1007/s11095-009-9912-4

Liver transporters in hepatic drug disposition: An update

Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009). Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 (5), 482-498. doi: 10.2174/138920009788898037

Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity

Yan, J., Gong, Y. W., She, Y. M., Wang, G. Q., Roberts, M. S. and Burczynski, F. J. (2009). Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity. Journal of Lipid Research, 50 (12), 2445-2454. doi: 10.1194/jlr.M900177-JLR200

Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L.- A. and Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International Journal of Pharmaceutics, 382 (1-2), 192-197. doi: 10.1016/j.ijpharm.2009.08.028

Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide

Mohamed, Fahim, Gawarammana, Indika, Robertson, Thomas A., Roberts, Michael S., Palangasinghem, Chathura, Zawahir, Shukry, Jayamanne, Shaluka, Kandasamy, Jaganathan, Eddleston, Michael, Buckley, Nick A., Dawson, Andrew H and Roberts, Darren M. (2009). Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide. PLoS One, 4 (4) e5127, 1-5. doi: 10.1371/journal.pone.0005127

A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis

Kruger, Peter S., Freir, Noelle M., Venkatesh, Bala, Robertson, Thomas A, Roberts, Michael S. and Jones, Mark (2009). A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis. Intensive Care Medicine, 35 (4), 717-721. doi: 10.1007/s00134-008-1358-3

Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44

Cutaneous metabolism in transdermal drug delivery

Zhang, Qian, Grice, Jeffrey E., Wang, Guangji and Roberts, Michael S. (2009). Cutaneous metabolism in transdermal drug delivery. Current Drug Metabolism, 10 (3), 227-235. doi: 10.2174/138920009787846350

Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics

Anissimov, Y. and Roberts, M. S. (2009). Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics. Journal of Pharmaceutical Sciences, 98 (2), 772-781. doi: 10.1002/jps.21461

Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies

Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H, Siahi-Shadbad, M. R., Mojarrad, J. S., Robertson, T. and Roberts, MS (2009). Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies. AAPS PHARMSCITECH, 10 (2), 649-659. doi: 10.1208/s12249-009-9248-8

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

Park, Sunwoo, Ropella, Glen E. P., Kim, Sean H. J., Roberts, Michael S. and Hunt, C. Anthony (2009). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of Pharmacology and Experimental Therapeutics, 328 (1), 294-305. doi: 10.1124/jpet.108.142497

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M.S. (2009). Interventions that can reduce inappropriate prescribing in the elderly: A systematic review. Drugs & Ageing, 26 (12), 1013-1028. doi: 10.2165/11318890-000000000-00000

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6), xx-xx. doi: 10.1186/cc8184

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

Roberts, Michael S., Roberts, Matthew J., Robertson, Thomas A., Sanchez, Washington, Thorling, Camilla, Zou, Yuhong, Zhao, Xin, Becker, Wolfgang and Zvyagin, Andrei V. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1 (6), 478-493. doi: 10.1002/jbio.200810058

Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat

Xai, Chun-hua, Sun, Jian-guo, Hao, Hai-ping, Wang, Guang-ji, Yan, Bei, Gu, Sheng-hua, Zheng, Chao-nan, Shang, Li-li and Roberts, Michael S. (2008). Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat. Planta Medica, 74 (15), 1832-1836. doi: 10.1055/s-0028-1088339

Common skin conditions and disorders

Roberts, Michael S. (2008). Common skin conditions and disorders. Drug Discovery Today: Disease Mechanisms, 5 (2), 125-126. doi: 10.1016/j.ddmec.2008.09.008

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin

Weiss, Michael, Hung, Daniel Y., Poenicke, Klaus and Roberts, Michael S. (2008). Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. European Journal of Pharmaceutical Sciences, 34 (4-5), 345-350. doi: 10.1016/j.ejps.2008.05.007

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

Cross, Sheree E. and Roberts, Michael S. (2008). Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes. Journal of Pharmaceutical Sciences, 97 (8), 3442-3450. doi: 10.1002/jps.21253

Nanotechnology, cosmetics and the skin: Is there a health risk?

Nohynek, G. J., Dufour, E. K. and Roberts, M. S. (2008). Nanotechnology, cosmetics and the skin: Is there a health risk?. Skin Pharmacology & Physiology, 21 (3), 136-149. doi: 10.1159/000131078

Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver

Yan, Li, Ropella, Glen E. P., Park, Sunwoo, Roberts, Michael S. and Hunt, C. Anthony (2008). Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver. Pharmaceutical Research, 25 (5), 1023-1036. doi: 10.1007/s11095-007-9494-y

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013

Skin diseases

Roberts, Michael S. (2008). Skin diseases. Drug Discovery Today: Disease Mechanisms, 5 (1), e1-e2. doi: 10.1016/j.ddmec.2008.09.007

An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics

Winckle, G., Anissimov, Y. G., Cross, S. E., Wise, G. and Roberts, M. S. (2008). An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics. Pharmaceutical Research, 25 (1), 158-166. doi: 10.1007/s11095-007-9416-z

Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro

Cross, S. E., Russel, M., Southwell, I. and Roberts, M. S. (2008). Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro. European Journal of Pharmaceutics And Biopharmaceutics, 69 (1), 214-222. doi: 10.1016/j.ejpb.2007.10.002

Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo

Zvyagin, Andrei V., Zhao, Xin, Gierden, Audrey, Sanchez, Washington, Ross, Justin A. and Roberts, Michael. S. (2008). Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo. Journal of Biomedical Optics, 13 (6) 064031, 064031-1-064031-9. doi: 10.1117/1.3041492

Non-melanoma skin cancers

Ahmed, A. H., Soyer, H. P., Saunders, N., Boukamp, P. and Roberts, M. S. (2008). Non-melanoma skin cancers. Drug Discovery Today: Disease Mechanisms, 5 (1), e55-e62. doi: 10.1016/j.ddmec.2008.05.007

Potential therapeutic effects of a traditional Chinese formulation, BJ-Jn on liver fibrosis induced by carbon tetrachloride in rats

Zou, Y., Yang, Y., Li, J., Wu, Q., Li, W-P, Lu, J-T and Roberts, M.S. (2008). Potential therapeutic effects of a traditional Chinese formulation, BJ-Jn on liver fibrosis induced by carbon tetrachloride in rats. Journal Of Ethnopharmacology, 120 (3), 452-457. doi: 10.1016/j.jep.2008.09.023

Skin biology, xerosis, barrier repair and measurement

Rawlings, A. V., Matts, P. J., Anderson, C. D. and Roberts, M. S. (2008). Skin biology, xerosis, barrier repair and measurement. Drug Discovery Today: Disease Mechanisms, 5 (2), e127-e136. doi: 10.1016/j.ddmec.2008.03.001

Skin, drug and chemical reactions

Alenius, H., Roberts, D. W., Tokura, Y., Lauerma, A., Patlewicz, G. and Roberts, M. S. (2008). Skin, drug and chemical reactions. Drug Discovery Today: Disease Mechanisms, 5 (2), e211-e220. doi: 10.1016/j.ddmec.2008.06.001

The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement

Li, P., Wang, G-J., Li, J., Liu, X., Khlentzos, A. and Roberts, M. S. (2008). The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement. Current Drug Metabolism, 9 (1), 39-45. doi: 10.2174/138920008783331103

Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement

Dalley, Andrew J., Lipman, Jeffrey, Venkatesh, Bala, Rudds, Michael, Roberts, Michael S. and Cross, Sheree E. (2007). Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. Journal of Antimicrobial Chemotherapy, 60 (1), 166-169. doi: 10.1093/jac/dkm128

Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver

Arab, H. A., Cheung, K., Hickman, P. E., Potter, J. M., Kadkhodaee, M. and Roberts, M. S. (2007). Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver. Clinical And Experimental Pharmacology And Physiology, 34 (4), 332-338. doi: 10.1111/j.1440-1681.2007.04550.x

Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety

Nohynek, Gerhard J., Lademann, Jürgen, Ribaud, Christele and Roberts, Michael S. (2007). Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety. Critical Reviews In Toxicology, 37 (3), 251-277. doi: 10.1080/10408440601177780

Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas

Fanning, Kent John and Roberts, Michael S. (2007). Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas. Pharmaceutical Research, 24 (3), 512-520. doi: 10.1007/s11095-006-9167-2

Expression and antioxidant function of liver fatty acid binding protein in normal and bile-duct ligated rats

Wang, G. Q., Shen, H., Rajaraman, G., Roberts, M. S., Gong, Y. W., Jiang, P. and Burczynski, F. (2007). Expression and antioxidant function of liver fatty acid binding protein in normal and bile-duct ligated rats. European Journal of Pharmacology, 560 (1), 61-68. doi: 10.1016/j.ejphar.2007.01.015

Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized zinc oxide formulation

Cross, S. E., Innes, B., Roberts, M. S., Tsuzuki, T., Robertson, T. A. and McCormick, P. (2007). Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized zinc oxide formulation. Skin Pharmacology And Physiology, 20 (3), 148-154. doi: 10.1159/000098701

Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies

Atrux-Tallau, N., Pirot, F., Falson, F., Roberts, M. S. and Maibach, H. I. (2007). Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies. Archives of Dermatological Research, 299 (10), 507-511. doi: 10.1007/s00403-007-0789-y

Surfactant protein expression in human skin: Evidence and implications

Mo, Y.-K., Kankavi, O., Masci, P. P., Mellick, G. D., Whitehouse, M. W., Boyle, G. M., Parsons, P. G., Roberts, M. S. and Cross, S. E. (2007). Surfactant protein expression in human skin: Evidence and implications. Journal of Investigative Dermatology, 127 (2), 381-386. doi: 10.1038/sj.jid.5700561

The influence of the Pharmaceutical Benefits Scheme (PBS) on inappropriate prescribing in Australian nursing homes

King, M. A. and Roberts, M. S. (2007). The influence of the Pharmaceutical Benefits Scheme (PBS) on inappropriate prescribing in Australian nursing homes. Pharmacy World & Science, 29 (1), 39-42. doi: 10.1007/s11096-005-5618-9

Physiologically based synthetic models of hepatic disposition

Hunt, C. Anthony, Ropella, Glen E. P., Yan, Li, Hung, Daniel Y. and Roberts, Michael S. (2006). Physiologically based synthetic models of hepatic disposition. Journal of Pharmacokinetics and Pharmacodynamics, 33 (6), 737-772. doi: 10.1007/s10928-006-9031-3

Periodic electric field enhanced transport through membranes

Mollee, TR, Anissimov, YG and Roberts, MS (2006). Periodic electric field enhanced transport through membranes. Journal of Membrane Science, 278 (1-2), 290-300. doi: 10.1016/j.memsci.2004.10.049

Complementary medicines in Australian veterans. Reply

Stokes, J. A. and Roberts, M. S. (2006). Complementary medicines in Australian veterans. Reply. Journal of Pharmacy Practice and Research, 36 (1), 80-80.

Dialysis-assisted fiber optic spectroscopy for in situ biomedical sensing

Blazkiewicz, P., Blazkiewicz, K., Verhaege, A., Anissimov, Y. G., Roberts, M. S. and Zvyagin, A. V. (2006). Dialysis-assisted fiber optic spectroscopy for in situ biomedical sensing. Journal Of Biomedical Optics, 11 (1) 014033, 014033.1-014033.7. doi: 10.1117/1.2166086

Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation

Hung, Daniel Y., Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda, Crawford, Darrell H. G. and Roberts, Michael S. (2006). Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. American Journal of Physiology-gastrointestinal And Liver Physiology, 290 (2), G343-G351. doi: 10.1152/ajpgi.00155.2005

Medication management at home: medication risk factor prevalence and inter-relationships

Sorensen, L, Stokes, JA, Purdie, DM, Woodward, M and Roberts, MS (2006). Medication management at home: medication risk factor prevalence and inter-relationships. Journal of Clinical Pharmacy And Therapeutics, 31 (5), 485-491. doi: 10.1111/j.1365-2710.2006.00768.x

Percutaneous absorption of steroids: Determination of in vitro permeability and tissue reservoir characteristics in human skin layers

Magnusson, BM, Cross, SE, Winckle, G and Roberts, MS (2006). Percutaneous absorption of steroids: Determination of in vitro permeability and tissue reservoir characteristics in human skin layers. Skin Pharmacology And Physiology, 19 (6), 336-342. doi: 10.1159/000095254

Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells

Wang, GQ, Gong, YW, Anderson, J, Sun, DF, Minuk, G, Roberts, MS and Burczynski, FJ (2005). Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells. Hepatology, 42 (4), 871-879. doi: 10.1002/hep.20857

Assessing the cellular transmembrane electrical potential difference on the hepatic uptake of palmitate

Burczynski, FJ, Hung, D, Wang, GQ, Elmadhoun, B, Lewis, A, Chang, P, Rajaraman, G and Roberts, MS (2005). Assessing the cellular transmembrane electrical potential difference on the hepatic uptake of palmitate. Molecular And Cellular Biochemistry, 270 (1-2), 115-124. doi: 10.1007/s11010-005-5267-2

Biomimetic in silico devices

Hunt, C.A., Ropella, G. E. P., Roberts, M. S. and Yan, L. (2005). Biomimetic in silico devices. Lecture Notes in Computer Science: Computational Methods In Systems Biology, 3082, 34-42.

Complementary medicines use by Australian veterans

Ientile, C. S., Sorensen, L., Lemanski, L. and Roberts, M. S. (2005). Complementary medicines use by Australian veterans. Journal of Pharmacy Practice and Research, 35 (2), 110-111. doi: 10.1002/j.2055-2335.2005.tb00318.x

Follicular vs intercellular topical delivery: experiences in differentiating between the two using novel formulations of minoxidil and cyanoacrylate casting

Cross, S.E., Wu, Y. and Roberts, M. S. (2005). Follicular vs intercellular topical delivery: experiences in differentiating between the two using novel formulations of minoxidil and cyanoacrylate casting. Cosmetics, Aerosols & Toiletries in Australia, 17 (6), 18-20.

Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver

Hung, DY, Siebert, GA, Chang, P and Roberts, MS (2005). Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver. British Journal of Pharmacology, 145 (1), 57-65. doi: 10.1038/sj.bjp.0706148

Influence of anatomical site and topical formulation on skin penetration of sunscreens

Benson, H., Sarveiya, V., Risk, S. and Roberts, M. S. (2005). Influence of anatomical site and topical formulation on skin penetration of sunscreens. Therapeutics and Clinical Risk Management, 1 (3), 209-218.

Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials

Chilcott, R. P., Barai, N., Beezer, A. E., Brain, S. I., Brown, M. B., Bunge, A. L., Burgess, S. E., Cross, S. E., Dalton, C. H., Dias, M., Farinha, A., Finnin, B. C., Roberts, M. S., Green, D. M. and Gunt, H. (2005). Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials. Journal Of Pharmaceutical Sciences, 94 (3), 632-638. doi: 10.1002/jps.20229

Medication management at home: medication-related risk factors associated with poor health outcomes

Sorensen, L, Stokes, JA, Purdie, DM, Woodward, M and Roberts, MS (2005). Medication management at home: medication-related risk factors associated with poor health outcomes. Age And Ageing, 34 (6), 626-632. doi: 10.1093/ageing/afi202

Medication reviews in the community: results of a randomized, controlled effectiveness trial (vol 58, pg 648, 2004)

Sorensen, L, Stokes, JA, Purdie, DM, Woodward, M, Elliot, R and Roberts, MS (2005). Medication reviews in the community: results of a randomized, controlled effectiveness trial (vol 58, pg 648, 2004). British Journal of Clinical Pharmacology, 59 (3), 376-376. doi: 10.1111/j.1365-2125.2004.02376.x

Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin

Rajaraman, G., Roberts, M. S., Hung, D., Wang, G. Q. and Burczynski, F. J. (2005). Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin. Pharmaceutical Research, 22 (11), 1793-1804. doi: 10.1007/s11095-005-7248-2

Predicting skin flux for minimal toxicological exposure or maximal therapeutic delivery

Magnusson, BM, Pugh, JW and Roberts, MS (2005). Predicting skin flux for minimal toxicological exposure or maximal therapeutic delivery. Journal of Investigative Dermatology, 125 (3), A11-A11.

Reduced hepatic extraction of palmitate in steatosis correlated to lower level of liver fatty acid binding protein

Hung, Daniel Y., Siebert, Gerhard A., Chang, Ping, Burczynski, Frank J. and Roberts, Michael S. (2005). Reduced hepatic extraction of palmitate in steatosis correlated to lower level of liver fatty acid binding protein. American Journal of Physiology-gastrointestinal And Liver Physiology, 288 (1), G93-G100. doi: 10.1152/ajpgi.00196.2004

Sunscreen penetration of human skin and related keratinocyte toxicity after topical application

Hayden, C. G. J., Cross, S. E., Anderson, C., Saunders, N. A. and Roberts, M. S. (2005). Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin Pharmacology And Physiology, 18 (4), 170-174. doi: 10.1159/000085861

Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver

Chang, P., Hung, D. Y., Siebert, G. A., Bridle, K. and Roberts, M. S. (2005). Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. Digestive Diseases And Sciences, 50 (4), 745-752. doi: 10.1007/s10620-005-2567-z

Unidirectional inversion of ibuprofen in Caco-2 cells: Developing a suitable model for presystemic chiral inversion study

Hao, H. P., Wang, G. J., Sun, J. G., Ding, Z. Q., Wu, X. L. and Roberts, M. S. (2005). Unidirectional inversion of ibuprofen in Caco-2 cells: Developing a suitable model for presystemic chiral inversion study. Biological & Pharmaceutical Bulletin, 28 (4), 682-687. doi: 10.1248/bpb.28.682

Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells

Xie, H. T., Wang, G.J., Chen, M, Jiang, X. L., Li, H, Lv, H, Huang, C. R., Wang, R and Roberts, M (2005). Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells. Biological & Pharmaceutical Bulletin, 28 (2), 383-386. doi: 10.1248/bpb.28.383

A model to study intestinal and hepatic metabolism of propranolol in the dog

Mills, PC, Siebert, GA and Roberts, MS (2004). A model to study intestinal and hepatic metabolism of propranolol in the dog. Journal of Veterinary Pharmacology And Therapeutics, 27 (1), 45-48. doi: 10.1111/j.1365-2885.2004.00547.x

Detection of surfactant protein A (SP-A) and surfactant protein D (SP-D) in equine synovial fluid with immunoblotting

Kankavi, O and Roberts, MS (2004). Detection of surfactant protein A (SP-A) and surfactant protein D (SP-D) in equine synovial fluid with immunoblotting. Canadian Journal of Veterinary Research-revue Canadienne De Recherche Veterinaire, 68 (2), 146-149.

Diffusion modeling of percutaneous absorption kinetics: 3. Variable diffusion and partition coefficients, consequences for stratum corneum depth profiles and desorption kinetics

Anissimov, YG and Roberts, MS (2004). Diffusion modeling of percutaneous absorption kinetics: 3. Variable diffusion and partition coefficients, consequences for stratum corneum depth profiles and desorption kinetics. Journal of Pharmaceutical Sciences, 93 (2), 470-487. doi: 10.1002/jps.10567

Disposition kinetics of propranolol isomers in the perfused rat liver

Hung, Daniel Y., Siebert, Gerhard A., Chang, Ping, Anissimov, Yuri G. and Roberts, Michael S. (2004). Disposition kinetics of propranolol isomers in the perfused rat liver. Journal of Pharmacology And Experimental Therapeutics, 311 (2), 822-829. doi: 10.1124/jpet.104.070011

Factors affecting the formation of a skin reservoir for topically applied solutes

Roberts, M. S., Cross, S. E. and Anissimov, Y. G. (2004). Factors affecting the formation of a skin reservoir for topically applied solutes. Skin Pharmacology & Physiology, 17 (1), 3-16. doi: 10.1159/000074057

Factors influencing PRN medication use in nursing homes

Stokes, JA, Purdie, DM and Roberts, MS (2004). Factors influencing PRN medication use in nursing homes. Pharmacy World & Science, 26 (3), 148-154. doi: 10.1023/B:PHAR.0000026803.89436.a8

In-home medication reviews for war veterans: Early experience in Australia

Sorensen, L., King, M. A., Peck, R. and Roberts, M. S. (2004). In-home medication reviews for war veterans: Early experience in Australia. Journal of Pharmacy Practice and Research, 34 (2), 122-124. doi: 10.1002/jppr2004342100

Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients

Craft, J. A., Masci, P. P., Roberts, M. S., Brighton, T. A., Garrahy, P., Cox, S. and Marsh, N. A. (2004). Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. Blood Coagulation & Fibrinolysis, 15 (6), 475-482. doi: 10.1097/00001721-200408000-00006

Ion-trapping, microsomal binding, and unbound drug distribution in the hepatic retention of basic drugs

Siebert, Gerhard A., Hung, Daniel Y., Chang, Ping and Roberts, Michael S. (2004). Ion-trapping, microsomal binding, and unbound drug distribution in the hepatic retention of basic drugs. Journal of Pharmacology And Experimental Therapeutics, 308 (1), 228-235. doi: 10.1124/jpet.103.056770

Medication reviews in the community: results of a randomized, controlled effectiveness trial

Sorensen, Lene, Stokes, Julie A., Purdie, David M., Woodward, Michael, Elliott, Rohan and Roberts, Michael S. (2004). Medication reviews in the community: results of a randomized, controlled effectiveness trial. British Journal of Clinical Pharmacology, 58 (6), 648-664. doi: 10.1111/j.1365-2125.2004.02220.x

Molecular size as the main determinant of solute maximum flux across the skin

Magnusson, B. M., Anissimov, Y. G., Cross, S. E. and Roberts, M. S. (2004). Molecular size as the main determinant of solute maximum flux across the skin. Journal of Investigative Dermatology, 122 (4), 993-999. doi: 10.1111/j.0022-202X.2004.22413.x

Physical enhancement of transdermal drug application: is delivery technology keeping up with pharmaceutical development?

Cross, S. E. and Roberts, M. S. (2004). Physical enhancement of transdermal drug application: is delivery technology keeping up with pharmaceutical development?. Current Drug Delivery, 1 (1), 81-92. doi: 10.2174/1567201043480045

Simple rules defining the potential of compounds for transdermal delivery or toxicity

Magnusson, Beatrice M., Pugh, W.John and Roberts, Michael S. (2004). Simple rules defining the potential of compounds for transdermal delivery or toxicity. Pharmaceutical Research, 21 (6), 1047-1054. doi: 10.1023/B:PHAM.0000029295.38564.e1

Unexpected clobetasol propionate profile in human stratum corneum after topical application in vitro

Mueller, B., Anissimov, Y. G. and Roberts, M. S. (2003). Unexpected clobetasol propionate profile in human stratum corneum after topical application in vitro. Pharmaceutical Research, 20 (11), 1835-1837. doi: 10.1023/B:PHAM.0000003382.20030.54

Bovine-serum-albumin-containing receptor phase better predicts transdermal absorption parameters for lipophilic compounds

Cross, Sheree E., Anissimov, Yuri G., Magnusson, Beatrice M. and Roberts, Michael S. (2003). Bovine-serum-albumin-containing receptor phase better predicts transdermal absorption parameters for lipophilic compounds. Journal of Investigative Dermatology, 120 (4), 589-591. doi: 10.1046/j.1523-1747.2003.12083.x

Determination of the effect of lipophilicity on the in vitro permeability and tissue reservoir characteristics of topically applied solutes in human skin layers

Cross, Sheree E., Magnusson, Beatrice M., Winckle, Gareth, Anissimov, Yuri and Roberts, Michael S. (2003). Determination of the effect of lipophilicity on the in vitro permeability and tissue reservoir characteristics of topically applied solutes in human skin layers. Journal of Investigative Dermatology, 120 (5), 759-764. doi: 10.1046/j.1523-1747.2003.12131.x

Development of a quality use of medicines coding system to rate clinical pharmacists' medication review recommendations

Sorensen, L, Grobler, MP and Roberts, MS (2003). Development of a quality use of medicines coding system to rate clinical pharmacists' medication review recommendations. Pharmacy World & Science, 25 (5), 212-217. doi: 10.1023/A:1025860615268

Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro

Rosado, C, Cross, SE, Pugh, WJ, Roberts, MS and Hadgraft, J (2003). Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro. Pharmaceutical Research, 20 (9), 1502-1507. doi: 10.1023/A:1025778731901

Explicit evidence-based prescribing criteria - an important step in achieving quality therapeutics in nursing homes

Roberts, M. S. and Stokes, J. A. (2003). Explicit evidence-based prescribing criteria - an important step in achieving quality therapeutics in nursing homes. Age And Ageing, 32 (1), 6-7. doi: 10.1093/ageing/32.1.6

Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites

Hung, DY, Burczynski, FJ, Chang, P, Lewis, A, Masci, PP, Siebert, GA, Anissimov, YG and Roberts, MS (2003). Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites. American Journal of Physiology-gastrointestinal And Liver Physiology, 284 (3), G423-G433. doi: 10.1152/ajpgi.00328.2002

Has drug therapy gone to the dogs?

Sorensen, L., King, M. A., Ientile, C. S. and Roberts, M. S. (2003). Has drug therapy gone to the dogs?. Age And Ageing, 32 (4), 460-461. doi: 10.1093/ageing/32.4.460

Transdermal penetration of vasoconstrictors - Present understanding and assessment of the human epidermal flux and retention of free bases and ion-pairs

Cross, SE, Thompson, MJ and Roberts, MS (2003). Transdermal penetration of vasoconstrictors - Present understanding and assessment of the human epidermal flux and retention of free bases and ion-pairs. Pharmaceutical Research, 20 (2), 270-274. doi: 10.1023/A:1022235507186

Cationic drug pharmacokinetics in diseased livers determined by fibrosis index, hepatic protein content, microsomal activity, and nature of drug

Hung, D. Y., Chang, P., Cheung, K., McWhinney, B., Masci, P. P., Weiss, M. and Roberts, M. S. (2002). Cationic drug pharmacokinetics in diseased livers determined by fibrosis index, hepatic protein content, microsomal activity, and nature of drug. Journal of Pharmacology and Experimental Therapeutics, 301 (3), 1079-1087. doi: 10.1124/jpet.301.3.1079

A compartmental model of hepatic disposition kinetics: 1. Model development and application to linear kinetics

Anissimov, YG and Roberts, MS (2002). A compartmental model of hepatic disposition kinetics: 1. Model development and application to linear kinetics. Journal of Pharmacokinetics And Pharmacodynamics, 29 (2), 131-156. doi: 10.1023/A:1019703607647

Catheter effects in organ perfusion experiments

Anissimov, Yuri G., Bracken, Anthony J. and Roberts, Michael S. (2002). Catheter effects in organ perfusion experiments. Journal of Theoretical Biology, 214 (2), 263-273. doi: 10.1006/jtbi.2001.2450

Distribution kinetics of solutes in the isolated in-situ perfused rat head using the multiple indicator dilution technique and a physiological two-barrier model

Foster, K. A., Weiss, M. and Roberts, M. S. (2002). Distribution kinetics of solutes in the isolated in-situ perfused rat head using the multiple indicator dilution technique and a physiological two-barrier model. Journal of Pharmacy And Pharmacology, 54 (3), 373-382. doi: 10.1211/0022357021778619

Effective pharmacist involvement in the healthcare team improves patient outcomes

Roberts, M. S. (2002). Effective pharmacist involvement in the healthcare team improves patient outcomes. Journal of Pharmacy Practice and Research, 32 (3), 171-174. doi: 10.1002/jppr2002323171

Enterohepatic circulation - Physiological, pharmacokinetic and clinical implications

Roberts, M. S., Magnusson, B. M., Burczynski, F. J. and Weiss, M. (2002). Enterohepatic circulation - Physiological, pharmacokinetic and clinical implications. Clinical Pharmacokinetics, 41 (10), 751-790. doi: 10.2165/00003088-200241100-00005

Pro re nata medication for psychoses: An audit of practice in two metropolitan hospitals

Geffen, Josh, Sorensen, Lene, Stokes, Julie, Cameron, Allison, Roberts, Michael S. and Geffen, Laurence (2002). Pro re nata medication for psychoses: An audit of practice in two metropolitan hospitals. Australian and New Zealand Journal of Psychiatry, 36 (5), 649-656. doi: 10.1046/j.1440-1614.2002.01069.x

Pro re nata medication for psychoses: The knowledge and beliefs of doctors and nurses

Geffen, Josh, Cameron, Allison, Sorensen, Lene, Stokes, Julie, Roberts, Michael S. and Geffen, Laurence (2002). Pro re nata medication for psychoses: The knowledge and beliefs of doctors and nurses. Australian and New Zealand Journal of Psychiatry, 36 (5), 642-648. doi: 10.1046/j.1440-1614.2002.01068.x

Pro re nata medication for psychoses: an audit of practice in two metropolitan hospitals

Geffen, J, Sorensen, L, Stokes, J, Cameron, A, Roberts, MS and Geffen, L (2002). Pro re nata medication for psychoses: an audit of practice in two metropolitan hospitals. Australian And New Zealand Journal of Psychiatry, 36 (5), 649-656. doi: 10.1046/j.1440-1614.2002.01069.x

Pro re nata medication for psychoses: the knowledge and beliefs of doctors and nurses

Geffen, J, Cameron, A, Sorensen, L, Stokes, J, Roberts, MS and Geffen, L (2002). Pro re nata medication for psychoses: the knowledge and beliefs of doctors and nurses. Australian And New Zealand Journal of Psychiatry, 36 (5), 642-648. doi: 10.1046/j.1440-1614.2002.01068.x

Quantitative evaluation of altered hepatic spaces and membrane transport in fibrotic rat liver

Hung, D. Y., Chang, P., Cheung, K., Winterford, C. and Roberts, M. S. (2002). Quantitative evaluation of altered hepatic spaces and membrane transport in fibrotic rat liver. Hepatology, 36 (5), 1180-1189. doi: 10.1053/jhep.2002.36820

Mathematical models in percutaneous absorption

Roberts, Michael S., Anissimov, Yuri G. and Gonsalvez, Richard A. (2001). Mathematical models in percutaneous absorption. Journal of toxicology. Cutaneous and ocular toxicology, 20 (2-3), 221-270. doi: 10.1081/CUS-120001859

Structure-hepatic disposition relationships for cationic drugs in isolated perfused rat livers: Transmembrane exchange and cytoplasmic binding process

Hung, Daniel Y., Chang, Ping, Weiss, Michael and Roberts, Michael S. (2001). Structure-hepatic disposition relationships for cationic drugs in isolated perfused rat livers: Transmembrane exchange and cytoplasmic binding process. The Journal of Pharmacology and Experimental Therapeutics, 297 (2), 780-789.

Outcomes of a randomized controlled trial of a clinical pharmacy intervention in 52 nursing homes

Roberts, Michael S., Stokes, Julie A., King, Michelle A., Lynne, Teresa A., Purdie, David M., Glasziou, Paul P., Wilson, D. Andrew J., McCarthy, Sean T., Brooks, Geoffrey E., de Looze, Ferdinandus J. and Del Mar, Christopher B. (2001). Outcomes of a randomized controlled trial of a clinical pharmacy intervention in 52 nursing homes. British Journal of Clinical Pharmacology, 53 (3), 257-265. doi: 10.1046/j.1365-2125.2001.00347.x

An improved survival model of hypoxia/ischaemia in the piglet suitable for neuroprotection studies

Foster, K. A., Colditz, P. B., Lingwood, B. E., Burke, C., Dunster, K. R. and Roberts, M. S. (2001). An improved survival model of hypoxia/ischaemia in the piglet suitable for neuroprotection studies. Brain Research, 919 (1), 122-131. doi: 10.1016/S0006-8993(01)03011-6

Can increasing the viscosity of formulations be used to reduce the human skin penetration of the sunscreen oxybenzone?

Cross, Sheree E., Jiang, Ruoying, Benson, Heather A. E. and Roberts, Michael S. (2001). Can increasing the viscosity of formulations be used to reduce the human skin penetration of the sunscreen oxybenzone?. The Journal of Investigative Dermatology, 117 (1), 147-150. doi: 10.1046/j.1523-1747.2001.01398.x

Diffusion modeling of percutaneous absorption kinetics: 2. Finite vehicle volume and solvent deposited solids

Anissimov, Y. and Roberts, M. S. (2001). Diffusion modeling of percutaneous absorption kinetics: 2. Finite vehicle volume and solvent deposited solids. Journal of Pharmaceutical Science, 90 (4), 504-520. doi: 10.1002/1520-6017(200104)90:4<504::AID-JPS1008>3.0.CO;2-H

Hepatocyte [H-3]-palmitate uptake: effect of albumin surface charge modification

Burczynski, FJ, Wang, GQ, Elmadhoun, B, She, YM, Roberts, MS and Standing, KG (2001). Hepatocyte [H-3]-palmitate uptake: effect of albumin surface charge modification. Canadian Journal of Physiology And Pharmacology, 79 (10), 868-875. doi: 10.1139/cjpp-79-10-868

How to optimise use of medications in the elderly

Pillans, P. and Roberts, M. S. (2001). How to optimise use of medications in the elderly. Medicine Today, 2 (4), 60-64.

Impact of clinical pharmacy on drug use in nursing homes

Roberts, M. S. and Stokes, J. A. (2001). Impact of clinical pharmacy on drug use in nursing homes. Geriatrics & Aging, 4 (9), 36-38.

Matching prescription claims with medication data for nursing home residents: Implications for prescriber feedback, drug utilisation studies and selection of prescription claims database

King, M. A., Purdie, D. M. and Roberts, M. S. (2001). Matching prescription claims with medication data for nursing home residents: Implications for prescriber feedback, drug utilisation studies and selection of prescription claims database. Journal of Clinical Epidemiology, 54 (2), 202-209. doi: 10.1016/S0895-4356(00)00282-1

Microdialysis and response during regional chemotherapy by isolated limb infusion of melphalan for limb malignancies

Thompson, J. F., Siebert, G., Anissimov, Y., Smithers, B. M., Doubrovsky, A., Anderson, C. and Roberts, M. S. (2001). Microdialysis and response during regional chemotherapy by isolated limb infusion of melphalan for limb malignancies. British Journal of Cancer, 85 (2), 157-165. doi: 10.1054/bjoc.2001.1902

Multidisciplinary case conference reviews: Improving outcomes for nursing home residents, carers and health professionals

King, M. A. and Roberts, M. S. (2001). Multidisciplinary case conference reviews: Improving outcomes for nursing home residents, carers and health professionals. Pharmacy World & Science, 23 (2), 41-45. doi: 10.1023/A:1011215008000

Pharmacokinetics and pharmacodynamics of melphalan in isolated limb infusion for recurrent localized limb malignancy

Roberts, M. S., Wu, Z. Y., Siebert, G., Anissimov, Y., Thompson, J. F. and Smithers, B. M. (2001). Pharmacokinetics and pharmacodynamics of melphalan in isolated limb infusion for recurrent localized limb malignancy. Melanoma Research, 11 (4), 423-431. doi: 10.1097/00008390-200108000-00014

Probing the effect of vehicles on topical delivery: Understanding the basic relationship between solvent and solute penetration using silicone membranes

Cross, S. E., Pugh, J., Hadgraft, J. and Roberts, M. S. (2001). Probing the effect of vehicles on topical delivery: Understanding the basic relationship between solvent and solute penetration using silicone membranes. Pharmaceutical Research, 18 (7), 999-1005. doi: 10.1023/A:1010996513458

Saturable dose-response relationships for melphalan in melanoma treatment by isolated limb infusion in the nude rat

Roberts, M. S., Wu, Z., Siebert, G., Thompson, J. F. and Smithers, B. M. (2001). Saturable dose-response relationships for melphalan in melanoma treatment by isolated limb infusion in the nude rat. Melanoma Research, 11 (6), 611-618. doi: 10.1097/00008390-200112000-00007

Veterinary drug delivery: Potential for skin penetration enhancement

Magnusson, Beatrice M., Walters, Kenneth A. and Roberts, Michael S. (2001). Veterinary drug delivery: Potential for skin penetration enhancement. Advanced Drug Delivery Reviews, 50 (3), 205-227. doi: 10.1016/S0169-409X(01)00158-2

The effect of occlusion on epidermal penetration of parabens from a commercial allergy test ointment, acetone and ethanol vehicles

Cross, S. E. and Roberts, M. S. (2000). The effect of occlusion on epidermal penetration of parabens from a commercial allergy test ointment, acetone and ethanol vehicles. Journal of Investigative Dermatology, 115 (5), 914-918. doi: 10.1046/j.1523-1747.2000.00151.x

An isolated in-situ rat head perfusion model for pharmacokinetic studies

Foster, K. A., Mellick, G. D., Weiss, M. and Roberts, M. S. (2000). An isolated in-situ rat head perfusion model for pharmacokinetic studies. Pharmaceutical Research, 17 (2), 127-134. doi: 10.1023/A:1007500910566

Can tissue drug concentrations be monitored by microdialysis during or after isolated limb perfusion for melanoma treatment?

Wu, Z., Smithers, B. M., Anderson, C. and Roberts, M. S. (2000). Can tissue drug concentrations be monitored by microdialysis during or after isolated limb perfusion for melanoma treatment?. Melanoma Research, 10 (1), 47-54. doi: 10.1097/00008390-200010010-00007

Commentary: Using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics

Roberts, M. S., Anissimov, Y. G. and Weiss, M. (2000). Commentary: Using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics. Journal of Pharmaceutical Sciences, 89 (12), 1579-1586. doi: 10.1002/1520-6017(200012)89:12<1579::AID-JPS8>3.3.CO;2-P

Cytoplasmic binding and disposition kinetics of diclofenac in the isolated perfused rat liver

Weiss, M, Kuhlmann, O, Hung, DY and Roberts, MS (2000). Cytoplasmic binding and disposition kinetics of diclofenac in the isolated perfused rat liver. British Journal of Pharmacology, 130 (6), 1331-1338. doi: 10.1038/sj.bjp.0703448

Effect of ion pairing with alkylamines on the in-vitro dermal penetration and local tissue disposition of salicylates

Megwa, SA, Cross, SE, Whitehouse, MW, Benson, HAE and Roberts, MS (2000). Effect of ion pairing with alkylamines on the in-vitro dermal penetration and local tissue disposition of salicylates. Journal of Pharmacy and Pharmacology, 52 (8), 929-940. doi: 10.1211/0022357001774813

Erratum: Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration (Journal of Pharmaceutical Sciences (1999) 88 (1201-1209))

Anissimov, Y. G. and Roberts, M. S. (2000). Erratum: Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration (Journal of Pharmaceutical Sciences (1999) 88 (1201-1209)). Journal of Pharmaceutical Sciences, 89 (1), 144-144. doi: 10.1002/(SICI)1520-6017(200001)89:1<144::AID-JPS14>3.0.CO;2-U

Experimental methods for studying drug uptake in the head and brain

Foster, K. A. and Roberts, M. S. (2000). Experimental methods for studying drug uptake in the head and brain. Current Drug Metabolism, 1 (4), 333-356. doi: 10.2174/1389200003338901

Ion-pair formation as a strategy to enhance topical delivery of salicylic acid

Megwa, SA, Cross, SE, Benson, HAE and Roberts, MS (2000). Ion-pair formation as a strategy to enhance topical delivery of salicylic acid. Journal of Pharmacy and Pharmacology, 52 (8), 919-928. doi: 10.1211/0022357001774804

Kinetics of propranolol uptake in muscle, skin, and fat of the isolated perfused rat hindlimb

Roberts, M. S., Wu, Z. Y. and Weiss, M. (2000). Kinetics of propranolol uptake in muscle, skin, and fat of the isolated perfused rat hindlimb. European Journal of Pharmaceutical Sciences, 11 (2), 165-172. doi: 10.1016/S0928-0987(00)00095-6

Percutaneous absorption of topically applied NSAIDS and other compounds: Role of solute properties, skin physiology and delivery systems

Cross, Sheree E. and Roberts, Michael S. (1999). Percutaneous absorption of topically applied NSAIDS and other compounds: Role of solute properties, skin physiology and delivery systems. Inflammopharmacology, 7 (4), 339-350. doi: 10.1007/s10787-999-0028-6

Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration

Anissimov, Yuri G. and Roberts, Michael S. (1999). Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration. Journal of Pharmaceutical Sciences, 88 (11), 1201-1209. doi: 10.1021/js990053i

Overprescribing: have we made any progress?

Pillans, P. and Roberts, M. S. (1999). Overprescribing: have we made any progress?. Australian And New Zealand Journal of Medicine, 29 (4), 485-486. doi: 10.1111/j.1445-5994.1999.tb00747.x

Over the counter (OTC) oral remedies for arthritis and rheumatism: How effective are they?

Whitehouse, M. W., Roberts, M. S. and Brooks, P. M. (1999). Over the counter (OTC) oral remedies for arthritis and rheumatism: How effective are they?. Inflammopharmacology, 7 (2), 89-105. doi: 10.1007/BF02918382

A physiological pharmacokinetic model for solute disposition in tissues below a topical application site

Roberts, MS and Cross, SE (1999). A physiological pharmacokinetic model for solute disposition in tissues below a topical application site. Pharmaceutical Research, 16 (9), 1392-1398. doi: 10.1023/A:1018998908655

Absorption of sunscreens across human skin: an evaluation of commercial products for children and adults

Jiang, R, Roberts, MS, Collins, DM and Benson, HAE (1999). Absorption of sunscreens across human skin: an evaluation of commercial products for children and adults. British Journal of Clinical Pharmacology, 48 (4), 635-637. doi: 10.1046/j.1365-2125.1999.00056.x

An analysis of solute structure-human epidermal transport relationships in epidermal iontophoresis using the ionic mobility: pore model

Lai, PM and Roberts, MS (1999). An analysis of solute structure-human epidermal transport relationships in epidermal iontophoresis using the ionic mobility: pore model. Journal of Controlled Release, 58 (3), 323-333. doi: 10.1016/S0168-3659(98)00172-2

Defining a model to predict the distribution of topically applied growth factors and other solutes in excisional full-thickness wounds

Cross, SE and Roberts, MS (1999). Defining a model to predict the distribution of topically applied growth factors and other solutes in excisional full-thickness wounds. Journal of Investigative Dermatology, 112 (1), 36-41. doi: 10.1046/j.1523-1747.1999.00473.x

Interconnected-Tubes model of hepatic elimination: Steady-state considerations

Anissimov, YG, Bracken, AJ and Roberts, MS (1999). Interconnected-Tubes model of hepatic elimination: Steady-state considerations. Journal of Theoretical Biology, 199 (4), 435-447. doi: 10.1006/jtbi.1999.0970

Lateral iontophoretic solute transport in skin

Lai, PM, Anissimov, YG and Roberts, MS (1999). Lateral iontophoretic solute transport in skin. Pharmaceutical Research, 16 (1), 46-54. doi: 10.1023/A:1018862510646

Modeling of hepatic elimination and organ distribution kinetics with the extended convection-dispersion model

Roberts, MS and Anissimov, YG (1999). Modeling of hepatic elimination and organ distribution kinetics with the extended convection-dispersion model. Journal of Pharmacokinetics And Biopharmaceutics, 27 (4), 343-382. doi: 10.1023/A:1020992421184

Self promotion of deep tissue penetration and distribution of methylsalicylate after topical application

Cross, SE, Megwa, SA, Benson, HAE and Roberts, MS (1999). Self promotion of deep tissue penetration and distribution of methylsalicylate after topical application. Pharmaceutical Research, 16 (3), 427-433. doi: 10.1023/A:1018834021066

Statistical moments for placental transfer of solutes in man

Bernus, I, Roberts, MS, Rasiah, RL and Mortimer, RH (1999). Statistical moments for placental transfer of solutes in man. Journal of Pharmacy and Pharmacology, 51 (12), 1381-1389. doi: 10.1211/0022357991777209

Structure-hepatic disposition relationships for phenolic compounds

Mellick, GD and Roberts, MS (1999). Structure-hepatic disposition relationships for phenolic compounds. Toxicology and Applied Pharmacology, 158 (1), 50-60. doi: 10.1006/taap.1999.8682

Sunscreens: are Australians getting the good oil? Reply

Hayden, C. G. J., Roberts, M. S. and Benson, H. A. E. (1999). Sunscreens: are Australians getting the good oil? Reply. Australian And New Zealand Journal of Medicine, 29 (1), 104-104.

Targeting local tissues by transdermal application: Understanding drug physicochemical properties that best exploit protein binding and blood flow effects

Cross, SE and Roberts, MS (1999). Targeting local tissues by transdermal application: Understanding drug physicochemical properties that best exploit protein binding and blood flow effects. Drug Development Research, 46 (3-4), 309-315. doi: 10.1002/(SICI)1098-2299(199903/04)46:3/4<309::AID-DDR17>3.0.CO;2-H

Targeting local tissues by transdermal applications: Understanding drug physiochemical properties that best exploit protein binding and blood flow effects

Cross, Sheree E. and Roberts, Michael S. (1999). Targeting local tissues by transdermal applications: Understanding drug physiochemical properties that best exploit protein binding and blood flow effects. Drug Development Research, 46 (3-4), 309-315. doi: 10.1002/(SICI)1098-2299(199903/04)46:3/4

The back diffusion of glucose across human skin in vitro

Pellett, MA, Hadgraft, J and Roberts, MS (1999). The back diffusion of glucose across human skin in vitro. International Journal of Pharmaceutics, 193 (1), 27-35. doi: 10.1016/S0378-5173(99)00314-2

Sunscreens: Are Australians getting the good oil?

Hayden, C. G. J., Roberts, M. S. and Benson, H. A. E, (1998). Sunscreens: Are Australians getting the good oil?. Australian & New Zealand Journal of Medicine, 28 (5), 639-646. doi: 10.1111/j.1445-5994.1999.tb01606.x

Sunscreens: are Australians getting the good oil?

Hayden, CGJ, Roberts, MS and Benson, HAE (1998). Sunscreens: are Australians getting the good oil?. Australian and New Zealand Journal of Medicine, 28 (5), 639-646. doi: 10.1111/j.1445-5994.1998.tb00661.x

Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine

Whitehouse M.W., Turner A.G., Davis C.K.C. and Roberts M.S. (1998). Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine. Inflammopharmacology, 6 (1), 1-8. doi: 10.1007/s10787-998-0001-9

Epidermal iontophoresis: I. Development of the ionic mobility-pore model

Roberts, MS, Lai, PM and Anissimov, YG (1998). Epidermal iontophoresis: I. Development of the ionic mobility-pore model. Pharmaceutical Research, 15 (10), 1569-1578. doi: 10.1023/A:1011907201096

Epidermal iontophoresis: II. Application of the ionic mobility-pore model to the transport of local anesthetics

Lai, PM and Roberts, MS (1998). Epidermal iontophoresis: II. Application of the ionic mobility-pore model to the transport of local anesthetics. Pharmaceutical Research, 15 (10), 1579-1588. doi: 10.1023/A:1011959217935

Focused antithrombotic therapy: Novel anti-platelet salicylates with reduced ulcerogenic potential and higher first-pass detoxification than aspirin in rats

Mellick, GD, Masci, PP, Whitaker, AN, Whitehouse, MW and Roberts, MS (1998). Focused antithrombotic therapy: Novel anti-platelet salicylates with reduced ulcerogenic potential and higher first-pass detoxification than aspirin in rats. Journal of Laboratory And Clinical Medicine, 132 (6), 469-477. doi: 10.1016/S0022-2143(98)90124-X

Functional and structural characterization of isolated perfused stingray liver including effects of ischaemia/reperfusion

Arab, H., Walker, N. I., Cheung, K., Winterford, C., Hickman, P. E., Potter, J. M. and Roberts, M. S. (1998). Functional and structural characterization of isolated perfused stingray liver including effects of ischaemia/reperfusion. Journal of Comparative Pathology, 118 (3), 221-230. doi: 10.1016/S0021-9975(05)80128-8

Hepatic disposition and metabolite kinetics of a homologous series of diflunisal esters

Hung, DY, Mellick, GD, Anissimov, YG, Weiss, M and Roberts, MS (1998). Hepatic disposition and metabolite kinetics of a homologous series of diflunisal esters. Journal of Pharmaceutical Sciences, 87 (8), 943-951. doi: 10.1021/js970485y

Hepatic structure-pharmacokinetic relationships: The hepatic disposition and metabolite kinetics of a homologous series of O-acyl derivatives of salicylic acid

Hung, DY, Mellick, GD, Anissimov, YG, Weiss, M and Roberts, MS (1998). Hepatic structure-pharmacokinetic relationships: The hepatic disposition and metabolite kinetics of a homologous series of O-acyl derivatives of salicylic acid. British Journal of Pharmacology, 124 (7), 1475-1483. doi: 10.1038/sj.bjp.0701961

Hepatocellular distribution and elimination kinetics of diclofenac in the isolated perfused rat liver

Weiss, M, Kuhlmann, O, Kraus, GJ and Roberts, MS (1998). Hepatocellular distribution and elimination kinetics of diclofenac in the isolated perfused rat liver. Naunyn-schmiedebergs Archives of Pharmacology, 357 (4), R6-R6.

In vitro human epidermal and polyethylene membrane penetration and retention of the sunscreen benzophenone-3 from a range of solvents

Jiang, RY, Benson, HAE, Cross, SE and Roberts, MS (1998). In vitro human epidermal and polyethylene membrane penetration and retention of the sunscreen benzophenone-3 from a range of solvents. Pharmaceutical Research, 15 (12), 1863-1868. doi: 10.1023/A:1011958006973

Kinetic analysis of vascular marker distribution in perfused rat livers after regeneration following partial hepatectomy

Weiss, M, Ballinger, LN and Roberts, MS (1998). Kinetic analysis of vascular marker distribution in perfused rat livers after regeneration following partial hepatectomy. Journal of Hepatology, 29 (3), 476-481. doi: 10.1016/S0168-8278(98)80068-8

Medication prescribing and administration in nursing homes

Roberts, MS, King, M, Stokes, JA, Lynne, TA, Bonner, CJ, McCarthy, S, Wilson, A, Glasziou, P and Pugh, WJ (1998). Medication prescribing and administration in nursing homes. Age And Ageing, 27 (3), 385-392. doi: 10.1093/ageing/27.3.385

Prescriptions, practitioners and pharmacists

Roberts, MS and Stokes, JA (1998). Prescriptions, practitioners and pharmacists. Medical Journal of Australia, 168 (7), 317-318. doi: 10.5694/j.1326-5377.1998.tb138957.x

Relative dispersions of intra-albumin transit times across rat and elasmobranch perfused livers, and implications for intra- and inter-species scaling of hepatic clearance using microsomal data

Roberts, MS, Ballinger, LN and Weiss, M (1998). Relative dispersions of intra-albumin transit times across rat and elasmobranch perfused livers, and implications for intra- and inter-species scaling of hepatic clearance using microsomal data. Journal of Pharmacy And Pharmacology, 50 (8), 865-870. doi: 10.1111/j.2042-7158.1998.tb04001.x

The effect of protein binding on the hepatic first pass of O-acyl salicylate derivatives in the rat

Hung, D. Y., Mellick, G. D., Whitehead, B. D. and Roberts, M. S. (1998). The effect of protein binding on the hepatic first pass of O-acyl salicylate derivatives in the rat. Journal of Pharmacy and Pharmacology, 50 (1), 63-69. doi: 10.1111/j.2042-7158.1998.tb03306.x

The pharmacokinetics of a range of solutes using the isolated in-situ rat brain perfusion technique

Foster, KA and Roberts, MS (1998). The pharmacokinetics of a range of solutes using the isolated in-situ rat brain perfusion technique. Naunyn-schmiedebergs Archives of Pharmacology, 358 (1), R406-R406.

Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies

Cross, SE, Anderson, C and Roberts, MS (1998). Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies. British Journal of Clinical Pharmacology, 46 (1), 29-35. doi: 10.1046/j.1365-2125.1998.00045.x

Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb

Wu, Z. Y., Smithers, B. M. and Roberts, M. S. (1997). Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb. Melanoma Research, 7 (3), 252-264. doi: 10.1097/00008390-199706000-00010

An isolated perfused human placental lobule model for multiple indicator dilution studies

Rasiah, RL, Addison, RS, Roberts, MS and Mortimer, RH (1997). An isolated perfused human placental lobule model for multiple indicator dilution studies. Journal of Pharmacological And Toxicological Methods, 38 (1), 19-25. doi: 10.1016/S1056-8719(97)00032-4

Distribution kinetics of diazepam, lidocaine and antipyrine in the isolated perfused rat hindlimb

Weiss, M, Koester, A, Wu, ZY and Roberts, MS (1997). Distribution kinetics of diazepam, lidocaine and antipyrine in the isolated perfused rat hindlimb. Pharmaceutical Research, 14 (11), 1640-1643. doi: 10.1023/A:1012198922671

Impulse-response studies on tracer doses of [14C]lignocaine and its multiple metabolites in the perfused rat liver

Mellick, George D. and Roberts, Michael S. (1997). Impulse-response studies on tracer doses of [14C]lignocaine and its multiple metabolites in the perfused rat liver. Journal of Pharmacy and Pharmacology, 49 (10), 1008-1018. doi: 10.1111/j.2042-7158.1997.tb06033.x

Impulse-response studies on tracer doses of [C-14]lignocaine and its multiple metabolites in the perfused rat liver

Mellick, GD and Roberts, MS (1997). Impulse-response studies on tracer doses of [C-14]lignocaine and its multiple metabolites in the perfused rat liver. Journal of Pharmacy And Pharmacology, 49 (10), 1008-1018.

Interconnected-tubes model of hepatic elimination

Anissimov, YG, Bracken, AJ and Roberts, MS (1997). Interconnected-tubes model of hepatic elimination. Journal of Theoretical Biology, 188 (1), 89-101. doi: 10.1006/jtbi.1997.0455

Is there tissue penetration after application of topical salicylate formulations?

Cross, SE, Anderson, C, Thompson, MJ and Roberts, MS (1997). Is there tissue penetration after application of topical salicylate formulations?. Lancet, 350 (9078), 636-636. doi: 10.1016/S0140-6736(05)63324-7

Isolated limb perfusion with melphalan for human melanoma xenografts in the hindlimb of nude rats: A surviving animal model

Wu, ZY, Roberts, MS, Parsons, PG and Smithers, BM (1997). Isolated limb perfusion with melphalan for human melanoma xenografts in the hindlimb of nude rats: A surviving animal model. Melanoma Research, 7 (1), 19-26. doi: 10.1097/00008390-199702000-00004

Metabolite mean transit times in the liver as predicted by various models of hepatic elimination

Mellick, GD, Anissimov, YG, Bracken, AJ and Roberts, MS (1997). Metabolite mean transit times in the liver as predicted by various models of hepatic elimination. Journal of Pharmacokinetics And Biopharmaceutics, 25 (4), 477-505. doi: 10.1023/A:1025797126763

Methimazole and propylthiouracil equally cross the perfused human term placental lobule

Mortimer, RH, Cannell, GR, Addison, RS, Johnson, LP, Roberts, MS and Bernus, I (1997). Methimazole and propylthiouracil equally cross the perfused human term placental lobule. Journal of Clinical Endocrinology And Metabolism, 82 (9), 3099-3102. doi: 10.1210/jc.82.9.3099

Modeling of subcutaneous absorption kinetics of infusion solutions in the elderly using technetium

Roberts, MS, Lipschitz, S, Campbell, AJ, Wanwimolruk, S, McQueen, EG and McQueen, M (1997). Modeling of subcutaneous absorption kinetics of infusion solutions in the elderly using technetium. Journal of Pharmacokinetics And Biopharmaceutics, 25 (1), 1-21. doi: 10.1023/A:1025763509326

On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed

Weiss, M, Stedtler, C and Roberts, MS (1997). On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed. Bulletin of Mathematical Biology, 59 (5), 911-929. doi: 10.1016/S0092-8240(97)00036-0

Percutaneous absorption of sunscreen agents from liquid paraffin: Self-association of octyl salicylate and effects on skin flux

Jiang, RY, Roberts, MS, Prankerd, RJ and Benson, HAE (1997). Percutaneous absorption of sunscreen agents from liquid paraffin: Self-association of octyl salicylate and effects on skin flux. Journal of Pharmaceutical Sciences, 86 (7), 791-796. doi: 10.1021/js960523y

Relative dispersion of intravascular transit times during isolated human limb perfusions for recurrent melanoma

Roberts, MS, Wu, ZY, Rivory, LP, Smithers, BM, Egerton, WS and Weiss, M (1997). Relative dispersion of intravascular transit times during isolated human limb perfusions for recurrent melanoma. British Journal of Clinical Pharmacology, 44 (4), 347-351. doi: 10.1046/j.1365-2125.1997.t01-1-00593.x

Supersaturated solutions evaluated with an in vitro stratum corneum tape stripping technique

Pellett, MA, Roberts, MS and Hadgraft, J (1997). Supersaturated solutions evaluated with an in vitro stratum corneum tape stripping technique. International Journal of Pharmaceutics, 151 (1), 91-98. doi: 10.1016/S0378-5173(97)04897-7

Synthesis, identification, characterization, stability, solubility, and protein binding of ester derivatives of salicylic acid and diflunisal

Hung, DY, Mellick, GD, Prankerd, RJ and Roberts, MS (1997). Synthesis, identification, characterization, stability, solubility, and protein binding of ester derivatives of salicylic acid and diflunisal. International Journal of Pharmaceutics, 153 (1), 25-39. doi: 10.1016/S0378-5173(97)00075-6

Systemic absorption of sunscreen after topical application

Hayden, CGJ, Roberts, MS and Benson, HAE (1997). Systemic absorption of sunscreen after topical application. Lancet, 350 (9081), 863-864. doi: 10.1016/S0140-6736(05)62032-6

Targeted drug delivery to the skin and deeper tissues: Role of physiology, solute structure and disease

Roberts, MS (1997). Targeted drug delivery to the skin and deeper tissues: Role of physiology, solute structure and disease. Clinical And Experimental Pharmacology And Physiology, 24 (11), 874-879. doi: 10.1111/j.1440-1681.1997.tb02708.x

The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft

Wu, Z. Y., Smithers, B. M., Parsons, P. G. and Roberts, M. S. (1997). The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft. British Journal of Cancer, 75 (8), 1160-1166. doi: 10.1038/bjc.1997.200

Tissue and perfusate pharmacokinetics of melphalan in isolated perfused rat hindlimb

Wu, ZY, Smithers, BM and Roberts, MS (1997). Tissue and perfusate pharmacokinetics of melphalan in isolated perfused rat hindlimb. Journal of Pharmacology And Experimental Therapeutics, 282 (3), 1131-1138.

Local deep tissue penetration of compounds after dermal application: Structure-tissue penetration relationships

Singh, P and Roberts, MS (1996). Local deep tissue penetration of compounds after dermal application: Structure-tissue penetration relationships. Journal of Pharmacology and Experimental Therapeutics, 279 (2), 908-917.

Distribution of systemically administered ampicillin, benzylpenicillin, and flucloxacillin in excisional wounds in diabetic and normal rats and effects of local topical vasodilator treatment

Cross, SE, Thompson, MJ and Roberts, MS (1996). Distribution of systemically administered ampicillin, benzylpenicillin, and flucloxacillin in excisional wounds in diabetic and normal rats and effects of local topical vasodilator treatment. Antimicrobial Agents and Chemotherapy, 40 (7), 1703-1710. doi: 10.1128/AAC.40.7.1703

Epidermal permeability - Penetrant structure relationships .3. The effect of hydrogen bonding interactions and molecular size on diffusion across the stratum corneum

Pugh, WJ, Roberts, MS and Hadgraft, J (1996). Epidermal permeability - Penetrant structure relationships .3. The effect of hydrogen bonding interactions and molecular size on diffusion across the stratum corneum. International Journal of Pharmaceutics, 138 (2), 149-165. doi: 10.1016/0378-5173(96)04533-4

In vitro and in vivo evaluation in rabbits of a controlled release 5-fluorouracil subconjunctival implant based on poly(D,L-lactide-co-glycolide)

Wang, GJ, Tucker, IG, Roberts, MS and Hirst, LW (1996). In vitro and in vivo evaluation in rabbits of a controlled release 5-fluorouracil subconjunctival implant based on poly(D,L-lactide-co-glycolide). Pharmaceutical Research, 13 (7), 1059-1064. doi: 10.1023/A:1016062825360

The disposition of aspirin and salicylic acid in the isolated perfused rat liver: The effect of normal and retrograde flow on availability and mean transit time

Mellick, GD and Roberts, MS (1996). The disposition of aspirin and salicylic acid in the isolated perfused rat liver: The effect of normal and retrograde flow on availability and mean transit time. Journal of Pharmacy and Pharmacology, 48 (7), 738-743. doi: 10.1111/j.2042-7158.1996.tb03962.x

Maternal to fetal thyroxine transmission in the human term placenta is limited by inner ring deiodination

Mortimer, RH, Galligan, JP, Cannell, GR, Addison, RS and Roberts, MS (1996). Maternal to fetal thyroxine transmission in the human term placenta is limited by inner ring deiodination. Journal of Clinical Endocrinology & Metabolism, 81 (6), 2247-2249. doi: 10.1210/jc.81.6.2247

Modeling solute sorption into plastic tubing during organ perfusion and intravenous infusions

Roberts, MS (1996). Modeling solute sorption into plastic tubing during organ perfusion and intravenous infusions. Journal of Pharmaceutical Sciences, 85 (6), 655-665. doi: 10.1021/js9500621

Epidermal permeability: Penetrant structure relationships .2. The effect of H-bonding groups in penetrants on their diffusion through the stratum corneum

Roberts, MS, Pugh, WJ and Hadgraft, J (1996). Epidermal permeability: Penetrant structure relationships .2. The effect of H-bonding groups in penetrants on their diffusion through the stratum corneum. International Journal of Pharmaceutics, 132 (1-2), 23-32. doi: 10.1016/0378-5173(95)04278-4

The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb

Cross, SE, Wu, ZY and Roberts, MS (1996). The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb. Journal of Pharmacology and Experimental Therapeutics, 277 (1), 366-374.

Tissue distribution kinetics as determinant of transit time dispersion of drugs in organs: Application of a stochastic model to the rat hindlimb

Weiss, M and Roberts, MS (1996). Tissue distribution kinetics as determinant of transit time dispersion of drugs in organs: Application of a stochastic model to the rat hindlimb. Journal of Pharmacokinetics and Biopharmaceutics, 24 (2), 173-196. doi: 10.1007/BF02353488

High-performance liquid chromatographic assay for common sunscreening agents in cosmetic products, bovine serum albumin solution and human plasma

Jiang, R, Hayden, CGJ, Prankerd, RJ, Roberts, MS and Benson, HAE (1996). High-performance liquid chromatographic assay for common sunscreening agents in cosmetic products, bovine serum albumin solution and human plasma. Journal of Chromatography B: Biomedical Applications, 682 (1), 137-145. doi: 10.1016/0378-4347(96)00063-1

High-performance liquid chromatographic determination of phenol, 4-nitrophenol, β-naphthol and a number of their glucuronide and sulphate conjugates in organ perfusate

Thompson M.J., Ballinger L.N., Cross S.E. and Roberts M.S. (1996). High-performance liquid chromatographic determination of phenol, 4-nitrophenol, β-naphthol and a number of their glucuronide and sulphate conjugates in organ perfusate. Journal of Chromatography B: Biomedical Applications, 677 (1), 117-122. doi: 10.1016/0378-4347(95)00368-1

An optimized model for rat liver perfusion studies

Cheung, K, Hickman, PE, Potter, JM, Walker, NI, Jericho, M, Haslam, R and Roberts, MS (1996). An optimized model for rat liver perfusion studies. Journal of Surgical Research, 66 (1), 81-89. doi: 10.1006/jsre.1996.0376

Epidermal permeability penetrant structure relationships .1. An analysis of methods of predicting penetration of monofunctional solutes from aqueous solutions

Roberts, MS, Pugh, WJ, Hadgraft, J and Watkinson, AC (1995). Epidermal permeability penetrant structure relationships .1. An analysis of methods of predicting penetration of monofunctional solutes from aqueous solutions. International Journal of Pharmaceutics, 126 (1-2), 219-233. doi: 10.1016/0378-5173(95)04130-3

Availability and mean transit times of phenol and its metabolites in the isolated perfused rat liver: Normal and retrograde studies using tracer concentrations of phenol

Ballinger, LN, Cross, SE and Roberts, MS (1995). Availability and mean transit times of phenol and its metabolites in the isolated perfused rat liver: Normal and retrograde studies using tracer concentrations of phenol. Journal of Pharmacy and Pharmacology, 47 (11), 949-956. doi: 10.1111/j.2042-7158.1995.tb03276.x

High-performance liquid chromatographic assay for the measurement of melphalan and its hydrolysis products in perfusate and plasma and melphalan in tissues from human and rat isolated limb perfusions

Wu, Zhen-Yu, Thompson, Melanie J., Roberts, Michael S., Addison, Russell S., Cannell, Graeme R., Grabs, Anthony J. and Smithers, B. Mark (1995). High-performance liquid chromatographic assay for the measurement of melphalan and its hydrolysis products in perfusate and plasma and melphalan in tissues from human and rat isolated limb perfusions. Journal of Chromatography B: Biomedical Sciences and Applications, 673 (2), 267-279. doi: 10.1016/0378-4347(95)00277-5

Percutaneous absorption of salicylates from some commercially available topical products containing methyl salicylate or salicylate salts in rats

Megwa, SA, Benson, HAE and Roberts, MS (1995). Percutaneous absorption of salicylates from some commercially available topical products containing methyl salicylate or salicylate salts in rats. Journal of Pharmacy and Pharmacology, 47 (11), 891-896. doi: 10.1111/j.2042-7158.1995.tb03266.x

Prediction of cathodal iontophoretic transport of various anions across excised skin from different vehicles using conductivity measurements

Yoshida, NH and Roberts, MS (1995). Prediction of cathodal iontophoretic transport of various anions across excised skin from different vehicles using conductivity measurements. Journal of Pharmacy and Pharmacology, 47 (11), 883-890. doi: 10.1111/j.2042-7158.1995.tb03265.x

Influence of Physicochemical Parameters and Perfusate Flow-Rate On the Distribution of Solutes in the Isolated-Perfused Rat Hindlimb Determined by the Impulse-Response Technique

Wu, ZY, Cross, SE and Roberts, MS (1995). Influence of Physicochemical Parameters and Perfusate Flow-Rate On the Distribution of Solutes in the Isolated-Perfused Rat Hindlimb Determined by the Impulse-Response Technique. Journal of Pharmaceutical Sciences, 84 (8), 1020-1027. doi: 10.1002/jps.2600840820

Importance of Dermal Blood-Supply and Epidermis On the Transdermal Iontophoretic Delivery of Monovalent Cations

Cross, SE and Roberts, MS (1995). Importance of Dermal Blood-Supply and Epidermis On the Transdermal Iontophoretic Delivery of Monovalent Cations. Journal of Pharmaceutical Sciences, 84 (5), 584-592. doi: 10.1002/jps.2600840513

Modeling of Plasma-Levels of Drugs Following Transdermal Iontophoresis

Singh, P, Roberts, MS and Maibach, HI (1995). Modeling of Plasma-Levels of Drugs Following Transdermal Iontophoresis. Journal of Controlled Release, 33 (2), 293-298. doi: 10.1016/0168-3659(94)00101-Y

Deep Tissue Penetration of Bases and Steroids After Dermal Application in Rat

Singh, P and Roberts, MS (1994). Deep Tissue Penetration of Bases and Steroids After Dermal Application in Rat. Journal of Pharmacy and Pharmacology, 46 (12), 956-964. doi: 10.1111/j.2042-7158.1994.tb03250.x

Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusion of melanoma

Clark, J., Grabs, A. J., Parsons, P. G., Smithers, B. M., Addison, R. S. and Roberts, M. S. (1994). Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusion of melanoma. Melanoma Research, 4 (6), 365-370. doi: 10.1097/00008390-199412000-00004

Disappearance Kinetics of Solutes From Synovial-Fluid After Intraarticular Injection

Owen, SG, Francis, HW and Roberts, MS (1994). Disappearance Kinetics of Solutes From Synovial-Fluid After Intraarticular Injection. British Journal of Clinical Pharmacology, 38 (4), 349-355. doi: 10.1111/j.1365-2125.1994.tb04365.x

Effect of Perfusion Flow-Rate On the Tissue Uptake of Solutes After Dermal Application Using the Rat Isolated-Perfused Hindlimb Preparation

Cross, SE, Wu, ZY and Roberts, MS (1994). Effect of Perfusion Flow-Rate On the Tissue Uptake of Solutes After Dermal Application Using the Rat Isolated-Perfused Hindlimb Preparation. Journal of Pharmacy and Pharmacology, 46 (10), 844-850. doi: 10.1111/j.2042-7158.1994.tb03741.x

Dermal and Underlying Tissue Pharmacokinetics of Lidocaine After Topical Application

Singh, P and Roberts, MS (1994). Dermal and Underlying Tissue Pharmacokinetics of Lidocaine After Topical Application. Journal of Pharmaceutical Sciences, 83 (6), 774-782. doi: 10.1002/jps.2600830604

Effects of Vasoconstriction On Dermal Pharmacokinetics and Local Tissue Distribution of Compounds

Singh, P and Roberts, MS (1994). Effects of Vasoconstriction On Dermal Pharmacokinetics and Local Tissue Distribution of Compounds. Journal of Pharmaceutical Sciences, 83 (6), 783-791. doi: 10.1002/jps.2600830605

Role of Conductivity in Iontophoresis .2. Anodal Iontophoretic Transport of Phenylethylamine and Sodium Across Excised Human Skin

Yoshida, NH and Roberts, MS (1994). Role of Conductivity in Iontophoresis .2. Anodal Iontophoretic Transport of Phenylethylamine and Sodium Across Excised Human Skin. Journal of Pharmaceutical Sciences, 83 (3), 344-350. doi: 10.1002/jps.2600830316

Skin Permeability and Local Tissue Concentrations of Nonsteroidal Antiinflammatory Drugs After Topical Application

Singh, P and Roberts, MS (1994). Skin Permeability and Local Tissue Concentrations of Nonsteroidal Antiinflammatory Drugs After Topical Application. Journal of Pharmacology and Experimental Therapeutics, 268 (1), 144-151.

What Is the Transport-Limiting Barrier in Iontophoresis

Singh, P, Guy, RH, Roberts, MS and Maibach, HI (1994). What Is the Transport-Limiting Barrier in Iontophoresis. International Journal of Pharmaceutics, 101 (3), R1-R5. doi: 10.1016/0378-5173(94)90225-9

Physiological Pharmacokinetics of Solutes in the Isolated-Perfused Rat Hindlimb - Characterization of the Physiology with Changing Perfusate Flow, Protein-Content, and Temperature Using Statistical Moment Analysis

Wu, ZY, Rivory, LP and Roberts, MS (1993). Physiological Pharmacokinetics of Solutes in the Isolated-Perfused Rat Hindlimb - Characterization of the Physiology with Changing Perfusate Flow, Protein-Content, and Temperature Using Statistical Moment Analysis. Journal of Pharmacokinetics and Biopharmaceutics, 21 (6), 653-688. doi: 10.1007/BF01113500

Use of a Solute Container Interaction to Determine Protein-Binding - Application to Long-Chain Fatty-Acids

Mellick, GD and Roberts, MS (1993). Use of a Solute Container Interaction to Determine Protein-Binding - Application to Long-Chain Fatty-Acids. Journal of Pharmaceutical Sciences, 82 (10), 1067-1068. doi: 10.1002/jps.2600821019

Blood-Flow Measurements in Skin and Underlying Tissues by Microsphere Method - Application to Dermal Pharmacokinetics of Polar Nonelectrolytes

Singh, P and Roberts, MS (1993). Blood-Flow Measurements in Skin and Underlying Tissues by Microsphere Method - Application to Dermal Pharmacokinetics of Polar Nonelectrolytes. Journal of Pharmaceutical Sciences, 82 (9), 873-879. doi: 10.1002/jps.2600820903

Dermal and Underlying Tissue Pharmacokinetics of Salicylic-Acid After Topical Application

Singh, P and Roberts, MS (1993). Dermal and Underlying Tissue Pharmacokinetics of Salicylic-Acid After Topical Application. Journal of Pharmacokinetics and Biopharmaceutics, 21 (4), 337-373. doi: 10.1007/BF01061687

Subcutaneous Absorption Kinetics and Local Tissue Distribution of Interferon and Other Solutes

Cross, SE and Roberts, MS (1993). Subcutaneous Absorption Kinetics and Local Tissue Distribution of Interferon and Other Solutes. Journal of Pharmacy and Pharmacology, 45 (7), 606-609. doi: 10.1111/j.2042-7158.1993.tb05661.x

A Clinical-Trial of a Slow-Release Formulation of Acetylsalicylic-Acid in Patients At Risk for Preeclampsia

Shen, J, Wanwimolruk, S, Wilson, PD, Seddon, RJ and Roberts, MS (1993). A Clinical-Trial of a Slow-Release Formulation of Acetylsalicylic-Acid in Patients At Risk for Preeclampsia. British Journal of Clinical Pharmacology, 35 (6), 664-667. doi: 10.1111/j.1365-2125.1993.tb04200.x

Solute Molecular-Size and Transdermal Iontophoresis Across Excised Human Skin

Yoshida, NH and Roberts, MS (1993). Solute Molecular-Size and Transdermal Iontophoresis Across Excised Human Skin. Journal of Controlled Release, 25 (3), 177-195. doi: 10.1016/0168-3659(93)90077-I

Pathway and Kinetics of Prednisolone Metabolism in the Human Placenta

Addison, RS, Maguire, DJ, Mortimer, RH, Roberts, MS and Cannell, GR (1993). Pathway and Kinetics of Prednisolone Metabolism in the Human Placenta. Journal of Steroid Biochemistry and Molecular Biology, 44 (3), 315-320. doi: 10.1016/0960-0760(93)90093-C

Iontophoretic Transdermal Delivery of Salicylic-Acid and Lidocaine to Local Subcutaneous Structures

Singh, P and Roberts, MS (1993). Iontophoretic Transdermal Delivery of Salicylic-Acid and Lidocaine to Local Subcutaneous Structures. Journal of Pharmaceutical Sciences, 82 (2), 127-131. doi: 10.1002/jps.2600820203

Kinetics of Toxic Doses of Paraquat and the Effects of Hemoperfusion in the Dog

Pond, SM, Rivory, LP, Hampson, Ecgm and Roberts, MS (1993). Kinetics of Toxic Doses of Paraquat and the Effects of Hemoperfusion in the Dog. Journal of Toxicology-Clinical Toxicology, 31 (2), 229-246. doi: 10.3109/15563659309000391

Uptake of Solutes by Plastic Infusion Tubing Mathematical Solutions

Donaldson, JD, Roberts, MS and Polack, AE (1992). Uptake of Solutes by Plastic Infusion Tubing Mathematical Solutions. International Journal of Pharmaceutics, 88 (1-3), 351-367. doi: 10.1016/0378-5173(92)90334-X

Structure Transport Relationships in Transdermal Iontophoresis

Yoshida, NH and Roberts, MS (1992). Structure Transport Relationships in Transdermal Iontophoresis. Advanced Drug Delivery Reviews, 9 (2-3), 239-264. doi: 10.1016/0169-409X(92)90025-L

Aging and the Response of the Isolated Perfused-Rat-Liver to Vasoactive Drugs

Lecouteur, D, Rivory, LP, Roberts, MS and Pond, SM (1992). Aging and the Response of the Isolated Perfused-Rat-Liver to Vasoactive Drugs. Biochemical Pharmacology, 43 (4), 913-915. doi: 10.1016/0006-2952(92)90264-J

Axial Tissue Diffusion Can Account for the Disparity Between Current Models of Hepatic Elimination for Lipophilic Drugs

Rivory, LP, Roberts, MS and Pond, SM (1992). Axial Tissue Diffusion Can Account for the Disparity Between Current Models of Hepatic Elimination for Lipophilic Drugs. Journal of Pharmacokinetics and Biopharmaceutics, 20 (1), 19-61. doi: 10.1007/BF01143185

Model Representation of Salicylate Pharmacokinetics Using Unbound Plasma Salicylate Concentrations and Metabolite Urinary-Excretion Rates Following a Single Oral Dose

Shen, J, Wanwimolruk, S, Purves, RD, McQueen, EG and Roberts, MS (1991). Model Representation of Salicylate Pharmacokinetics Using Unbound Plasma Salicylate Concentrations and Metabolite Urinary-Excretion Rates Following a Single Oral Dose. Journal of Pharmacokinetics and Biopharmaceutics, 19 (5), 575-595. doi: 10.1007/BF01062964

Pharmacokinetics and Bioavailability of Naprosyn Cr 500 Mg Tablet, a New Controlled-Release Formulation of Naproxen, After Single and Multiple Dosing

Wanwimolruk, S, Lipschitz, S and Roberts, MS (1991). Pharmacokinetics and Bioavailability of Naprosyn Cr 500 Mg Tablet, a New Controlled-Release Formulation of Naproxen, After Single and Multiple Dosing. International Journal of Pharmaceutics, 75 (1), 55-62. doi: 10.1016/0378-5173(91)90250-R

Prediction of Solute Sorption by Polyvinyl-Chloride Plastic Infusion Bags

Roberts, MS, Kowaluk, EA and Polack, AE (1991). Prediction of Solute Sorption by Polyvinyl-Chloride Plastic Infusion Bags. Journal of Pharmaceutical Sciences, 80 (5), 449-455. doi: 10.1002/jps.2600800511

Effects of Posture and Sleep On the Pharmacokinetics of Paracetamol (acetaminophen) and its Metabolites

Rumble, RH, Roberts, MS and Denton, MJ (1991). Effects of Posture and Sleep On the Pharmacokinetics of Paracetamol (acetaminophen) and its Metabolites. Clinical Pharmacokinetics, 20 (2), 167-173. doi: 10.2165/00003088-199120020-00007

Rebound Elevation in Urinary Thromboxane-B2 and 6-Keto-Pgf1-Alpha-Excretion After Aspirin Withdrawal

Vial, JH, McLeod, LJ and Roberts, MS (1991). Rebound Elevation in Urinary Thromboxane-B2 and 6-Keto-Pgf1-Alpha-Excretion After Aspirin Withdrawal. Advances in Prostaglandin Thromboxane and Leukotriene Research, 21, 157-160.

Response to Beta-Blockers in Maternal and Fetal-Rat Hearts Invitro

Shen, JJ, Wanwimolruk, S, Mills, RG and Roberts, MS (1991). Response to Beta-Blockers in Maternal and Fetal-Rat Hearts Invitro. Life Sciences, 48 (18), 1737-1743. doi: 10.1016/0024-3205(91)90210-3

Subcutaneous Fluid Administration in Elderly Subjects - Validation of An Under-Used Technique

Lipschitz, S, Campbell, AJ, Roberts, MS, Wanwimolruk, S, McQueen, EG, McQueen, M and Firth, LA (1991). Subcutaneous Fluid Administration in Elderly Subjects - Validation of An Under-Used Technique. Journal of the American Geriatrics Society, 39 (1), 6-9. doi: 10.1111/j.1532-5415.1991.tb05898.x

Selective-Inhibition of Platelet Cyclooxygenase with Controlled Release, Low-Dose Aspirin

Vial, JH, McLeod, LJ, Roberts, MS and Seville, PR (1990). Selective-Inhibition of Platelet Cyclooxygenase with Controlled Release, Low-Dose Aspirin. Australian and New Zealand Journal of Medicine, 20 (5), 652-656. doi: 10.1111/j.1445-5994.1990.tb00394.x

Residence Time Distributions of Solutes in the Perfused-Rat-Liver Using a Dispersion Model of Hepatic Elimination .1. Effect of Changes in Perfusate Flow and Albumin Concentration On Sucrose and Taurocholate

Roberts, MS, Fraser, S, Wagner, A and McLeod, L (1990). Residence Time Distributions of Solutes in the Perfused-Rat-Liver Using a Dispersion Model of Hepatic Elimination .1. Effect of Changes in Perfusate Flow and Albumin Concentration On Sucrose and Taurocholate. Journal of Pharmacokinetics and Biopharmaceutics, 18 (3), 209-234. doi: 10.1007/BF01062200

Residence Time Distributions of Solutes in the Perfused-Rat-Liver Using a Dispersion Model of Hepatic Elimination .2. Effect of Pharmacological Agents, Retrograde Perfusions, and Enzyme-Inhibition On Evans Blue, Sucrose, Water, and Taurocholate

Roberts, MS, Fraser, S, Wagner, A and McLeod, L (1990). Residence Time Distributions of Solutes in the Perfused-Rat-Liver Using a Dispersion Model of Hepatic Elimination .2. Effect of Pharmacological Agents, Retrograde Perfusions, and Enzyme-Inhibition On Evans Blue, Sucrose, Water, and Taurocholate. Journal of Pharmacokinetics and Biopharmaceutics, 18 (3), 235-258. doi: 10.1007/BF01062201

A Sensitive Assay for Aspirin and its Metabolites Using Reversed-Phase Ion-Pair High-Performance Liquid-Chromatography

Shen, J, Wanwimolruk, S, Clark, CR and Roberts, MS (1990). A Sensitive Assay for Aspirin and its Metabolites Using Reversed-Phase Ion-Pair High-Performance Liquid-Chromatography. Journal of Liquid Chromatography, 13 (4), 751-761. doi: 10.1080/01483919008051818

Availability Predictions by Hepatic Elimination Models for Michaelis-Menten Kinetics

Roberts, MS, Donaldson, JD and Jackett, D (1989). Availability Predictions by Hepatic Elimination Models for Michaelis-Menten Kinetics. Journal of Pharmacokinetics and Biopharmaceutics, 17 (6), 687-719. doi: 10.1007/BF01062125

Salicylate Pharmacokinetics in Patients with Rheumatoid-Arthritis

Owen, SG, Roberts, MS, Friesen, WT and Francis, HW (1989). Salicylate Pharmacokinetics in Patients with Rheumatoid-Arthritis. British Journal of Clinical Pharmacology, 28 (4), 449-461. doi: 10.1111/j.1365-2125.1989.tb03526.x

Percutaneous-Absorption of Steroids - Relative Contributions of Epidermal Penetration and Dermal Clearance

Siddiqui, O, Roberts, MS and Polack, AE (1989). Percutaneous-Absorption of Steroids - Relative Contributions of Epidermal Penetration and Dermal Clearance. Journal of Pharmacokinetics and Biopharmaceutics, 17 (4), 405-424. doi: 10.1007/BF01061455

Iontophoretic Transport of Weak Electrolytes Through the Excised Human Stratum-Corneum

Siddiqui, O, Roberts, MS and Polack, AE (1989). Iontophoretic Transport of Weak Electrolytes Through the Excised Human Stratum-Corneum. Journal of Pharmacy and Pharmacology, 41 (6), 430-432. doi: 10.1111/j.2042-7158.1989.tb06495.x

Clinical Applicability of Current Pharmacokinetic Models - Splanchnic Elimination of 5-Fluorouracil in Cancer-Patients

Robinson, PJ, Bass, L, Pond, SM, Roberts, MS and Wagner, JG (1988). Clinical Applicability of Current Pharmacokinetic Models - Splanchnic Elimination of 5-Fluorouracil in Cancer-Patients. Journal of Pharmacokinetics and Biopharmaceutics, 16 (3), 229-249. doi: 10.1007/BF01062135

Low-Dose Enteric-Coated Aspirin as An Antiplatelet Preparation

McLeod, LJ, Roberts, MS and Seville, PR (1988). Low-Dose Enteric-Coated Aspirin as An Antiplatelet Preparation. Medical Journal of Australia, 148 (4), 207-207.

Models of Hepatic Elimination - Comparison of Stochastic-Models to Describe Residence Time Distributions and to Predict the Influence of Drug Distribution, Enzyme Heterogeneity, and Systemic Recycling On Hepatic Elimination

Roberts, MS, Donaldson, JD and Rowland, M (1988). Models of Hepatic Elimination - Comparison of Stochastic-Models to Describe Residence Time Distributions and to Predict the Influence of Drug Distribution, Enzyme Heterogeneity, and Systemic Recycling On Hepatic Elimination. Journal of Pharmacokinetics and Biopharmaceutics, 16 (1), 41-83. doi: 10.1007/BF01061862

The Effects of Posture On the Pharmacokinetics of Intramuscular Benzylpenicillin

Rumble, RH, Roberts, MS and Scott, AR (1988). The Effects of Posture On the Pharmacokinetics of Intramuscular Benzylpenicillin. European Journal of Clinical Pharmacology, 33 (6), 629-635. doi: 10.1007/BF00542500

High-Performance Liquid-Chromatographic Assay of the Major Components of Gentamicin in Serum

Rumble, RH and Roberts, MS (1987). High-Performance Liquid-Chromatographic Assay of the Major Components of Gentamicin in Serum. Journal of Chromatography-Biomedical Applications, 419 (C), 408-413. doi: 10.1016/0378-4347(87)80308-0

Hypocarbia and Muscle-Relaxant Plasma-Levels

Lamont, Asm, Roberts, MS and McLeod, LJ (1987). Hypocarbia and Muscle-Relaxant Plasma-Levels. Anaesthesia and Intensive Care, 15 (3), 354-355.

The Changing Nature of Pharmacy in the New-Zealand Health-Care System

Roberts, MS (1987). The Changing Nature of Pharmacy in the New-Zealand Health-Care System. New Zealand Medical Journal, 100 (830), 522-524.

On the Relation Between Extended Forms of the Sinusoidal Perfusion and of the Convection Dispersion Models of Hepatic Elimination

Bass, L, Roberts, MS and Robinson, PJ (1987). On the Relation Between Extended Forms of the Sinusoidal Perfusion and of the Convection Dispersion Models of Hepatic Elimination. Journal of Theoretical Biology, 126 (4), 457-482. doi: 10.1016/S0022-5193(87)80152-2

Rapid High-Performance Liquid-Chromatographic Assay for the Simultaneous Analysis of Nonsteroidal Antiinflammatory Drugs in Plasma

Owen, SG, Roberts, MS and Friesen, WT (1987). Rapid High-Performance Liquid-Chromatographic Assay for the Simultaneous Analysis of Nonsteroidal Antiinflammatory Drugs in Plasma. Journal of Chromatography-Biomedical Applications, 416 (2), 293-302. doi: 10.1016/0378-4347(87)80512-1

Relationship Between Methemoglobin Production and Methylene-Blue Plasma-Concentrations Under General-Anesthesia

Lamont, Asm, Roberts, MS, Holdsworth, DG, Atherton, A and Shepherd, JJ (1986). Relationship Between Methemoglobin Production and Methylene-Blue Plasma-Concentrations Under General-Anesthesia. Anaesthesia and Intensive Care, 14 (4), 360-364.

Extrahepatic Metabolism and Distribution of Aspirin in Vascular Beds of Sheep

Cossum, PA, Roberts, MS, Kilpatrick, D and Yong, AC (1986). Extrahepatic Metabolism and Distribution of Aspirin in Vascular Beds of Sheep. Journal of Pharmaceutical Sciences, 75 (8), 731-737. doi: 10.1002/jps.2600750802

A Dispersion Model of Hepatic Elimination .1. Formulation of the Model and Bolus Considerations

Roberts, MS and Rowland, M (1986). A Dispersion Model of Hepatic Elimination .1. Formulation of the Model and Bolus Considerations. Journal of Pharmacokinetics and Biopharmaceutics, 14 (3), 227-260. doi: 10.1007/BF01106706

A Dispersion Model of Hepatic Elimination .2. Steady-State Considerations - Influence of Hepatic Blood-Flow, Binding Within Blood, and Hepatocellular Enzyme-Activity

Roberts, MS and Rowland, M (1986). A Dispersion Model of Hepatic Elimination .2. Steady-State Considerations - Influence of Hepatic Blood-Flow, Binding Within Blood, and Hepatocellular Enzyme-Activity. Journal of Pharmacokinetics and Biopharmaceutics, 14 (3), 261-288. doi: 10.1007/BF01106707

A Dispersion Model of Hepatic Elimination .3. Application to Metabolite Formation and Elimination Kinetics

Roberts, MS and Rowland, M (1986). A Dispersion Model of Hepatic Elimination .3. Application to Metabolite Formation and Elimination Kinetics. Journal of Pharmacokinetics and Biopharmaceutics, 14 (3), 289-308. doi: 10.1007/BF01106708

Distribution and metabolism of nitroglycerin and its metabolites in vascular beds of sheep

Cossum, P.A., Roberts, M.S., Yong, A.C. and Kilpatrick, D. (1986). Distribution and metabolism of nitroglycerin and its metabolites in vascular beds of sheep. Journal of Pharmacology and Experimental Therapeutics, 237 (3), 959-966.

Kinetics of Sorption of Ionizable Solutes by Plastic Infusion Bags

Kowaluk, EA, Roberts, MS and Polack, AE (1986). Kinetics of Sorption of Ionizable Solutes by Plastic Infusion Bags. Journal of Pharmaceutical Sciences, 75 (6), 562-570. doi: 10.1002/jps.2600750608

Slow-Release Aspirin and Prostaglandin Inhibition

Roberts, MS, Joyce, RM, McLeod, LJ, Vial, JH and Seville, PR (1986). Slow-Release Aspirin and Prostaglandin Inhibition. Lancet, 1 (8490), 1153-1154.

Functional-Capacity and Treatment Data From a Community Based Study of Patients with Rheumatoid-Arthritis

Owen, SG, Friesen, WT, Roberts, MS, Francis, H and Flux, W (1986). Functional-Capacity and Treatment Data From a Community Based Study of Patients with Rheumatoid-Arthritis. Annals of the Rheumatic Diseases, 45 (4), 293-303. doi: 10.1136/ard.45.4.293

The Effects of Different Doses of Some Acetylsalicyclic Acid Formulations On Platelet-Function and Bleeding Times in Healthy-Subjects

McLeod, LJ, Roberts, MS, Cossum, PA and Vial, JH (1986). The Effects of Different Doses of Some Acetylsalicyclic Acid Formulations On Platelet-Function and Bleeding Times in Healthy-Subjects. Scandinavian Journal of Haematology, 36 (4), 379-384.

Correlation Between Invitro Microsomal-Enzyme Activity and Whole Organ Hepatic Elimination Kinetics - Analysis with a Dispersion Model

Roberts, MS and Rowland, M (1986). Correlation Between Invitro Microsomal-Enzyme Activity and Whole Organ Hepatic Elimination Kinetics - Analysis with a Dispersion Model. Journal of Pharmacy and Pharmacology, 38 (3), 177-181. doi: 10.1111/j.2042-7158.1986.tb04540.x

Drug Delivery Systems

Polack, AE and Roberts, MS (1986). Drug Delivery Systems. Medical Journal of Australia, 144 (6), 311-314.

Consequences of Wasp Stings

McLeod, LJ, Vonwitt, RJ and Roberts, MS (1986). Consequences of Wasp Stings. Medical Journal of Australia, 144 (4), 220-221.

The Effect of Posture On the Pharmacokinetics of Intravenous Benzylpenicillin

Rumble, RH, Roberts, MS and Scott, AR (1986). The Effect of Posture On the Pharmacokinetics of Intravenous Benzylpenicillin. European Journal of Clinical Pharmacology, 30 (6), 731-734. doi: 10.1007/BF00608225

The Pharmacokinetics of Tetrabenazine and its Hydroxy Metabolite in Patients Treated for Involuntary Movement-Disorders

Roberts, MS, McLean, S, Millingen, KS and Galloway, HM (1986). The Pharmacokinetics of Tetrabenazine and its Hydroxy Metabolite in Patients Treated for Involuntary Movement-Disorders. European Journal of Clinical Pharmacology, 29 (6), 703-708. doi: 10.1007/BF00615962

Implications of hepatic and extrahepatic metabolism of aspirin in selective inhibition of platelet cyclooxygenase

Roberts, M. S., Cossum, P. A. and Kilpatrick, D. (1985). Implications of hepatic and extrahepatic metabolism of aspirin in selective inhibition of platelet cyclooxygenase. New England Journal of Medicine, 312 (21), 1388-1389. doi: 10.1056/NEJM198505233122113

Comparison of Models Describing the Sorption of Nitroglycerin and Diazepam by Plastic Infusion Systems - Diffusion and Compartment Models

Kowaluk, EA, Roberts, MS and Polack, AE (1985). Comparison of Models Describing the Sorption of Nitroglycerin and Diazepam by Plastic Infusion Systems - Diffusion and Compartment Models. Journal of Pharmaceutical Sciences, 74 (6), 625-633. doi: 10.1002/jps.2600740609

Determinants of Compliance in Rheumatoid Arthritic Patients Assessed in Their Home-Environment

Owen, SG, Friesen, WT, Roberts, MS and Flux, W (1985). Determinants of Compliance in Rheumatoid Arthritic Patients Assessed in Their Home-Environment. British Journal of Rheumatology, 24 (4), 313-320.

Determination of Benzylpenicillin in Plasma and Urine by High-Performance Liquid-Chromatography

Rumble, RH and Roberts, MS (1985). Determination of Benzylpenicillin in Plasma and Urine by High-Performance Liquid-Chromatography. Journal of Chromatography, 342 (2), 436-441. doi: 10.1016/S0378-4347(00)84540-5

Hepatic Elimination - Dispersion Model

Roberts, MS and Rowland, M (1985). Hepatic Elimination - Dispersion Model. Journal of Pharmaceutical Sciences, 74 (5), 585-587. doi: 10.1002/jps.2600740522

Metabolite Inhibition of Nitroglycerin Metabolism in Sheep Tissue-Homogenates

Cossum, PA and Roberts, MS (1985). Metabolite Inhibition of Nitroglycerin Metabolism in Sheep Tissue-Homogenates. Journal of Pharmacy and Pharmacology, 37 (11), 807-809. doi: 10.1111/j.2042-7158.1985.tb04972.x

Nitroglycerin Disposition in Human-Blood

Cossum, PA and Roberts, MS (1985). Nitroglycerin Disposition in Human-Blood. European Journal of Clinical Pharmacology, 29 (2), 169-175. doi: 10.1007/BF00547417

The Effect of Iontophoresis and Vehicle Ph On the Invitro Permeation of Lignocaine Through Human Stratum-Corneum

Siddiqui, O, Roberts, MS and Polack, AE (1985). The Effect of Iontophoresis and Vehicle Ph On the Invitro Permeation of Lignocaine Through Human Stratum-Corneum. Journal of Pharmacy and Pharmacology, 37 (10), 732-735. doi: 10.1111/j.2042-7158.1985.tb04954.x

The Effects of Nifedipine On the Systemic and Coronary Vascular Beds of the Sheep - a Potential Method for Induction of Ischemia

Fu, WK, Yong, AC, Gangell, P, Roberts, MS and Kilpatrick, D (1985). The Effects of Nifedipine On the Systemic and Coronary Vascular Beds of the Sheep - a Potential Method for Induction of Ischemia. Clinical and Experimental Pharmacology and Physiology, 12 (4), 407-415. doi: 10.1111/j.1440-1681.1985.tb00888.x

The Pharmacokinetics and Bioavailability of a Tracer Dose of [h-3] Mebendazole in Man

Dawson, M, Braithwaite, PA, Roberts, MS and Watson, TR (1985). The Pharmacokinetics and Bioavailability of a Tracer Dose of [h-3] Mebendazole in Man. British Journal of Clinical Pharmacology, 19 (1), 79-86. doi: 10.1111/j.1365-2125.1985.tb02616.x

Topical Absorption of Methotrexate - Role of Dermal Transport

Siddiqui, O, Roberts, MS and Polack, AE (1985). Topical Absorption of Methotrexate - Role of Dermal Transport. International Journal of Pharmaceutics, 27 (2-3), 193-203. doi: 10.1016/0378-5173(85)90069-9

A Rapid Method for Determination of Acetylation Phenotype Using Dapsone

Philip, PA, Roberts, MS and Rogers, HJ (1984). A Rapid Method for Determination of Acetylation Phenotype Using Dapsone. British Journal of Clinical Pharmacology, 17 (4), 465-469. doi: 10.1111/j.1365-2125.1984.tb02373.x

An Audit of Therapeutic Drug-Monitoring Procedures - Use of Theophylline Assay Services

Dsouza, CA, Friesen, WT, Vonwitt, RJ, Taylor, GR and Roberts, MS (1984). An Audit of Therapeutic Drug-Monitoring Procedures - Use of Theophylline Assay Services. Journal of Clinical and Hospital Pharmacy, 9 (1), 53-59. doi: 10.1111/j.1365-2710.1984.tb00918.x

Dynamics of Clomethiazole Edisylate Interaction with Plastic Infusion Systems

Kowaluk, EA, Roberts, MS and Polack, AE (1984). Dynamics of Clomethiazole Edisylate Interaction with Plastic Infusion Systems. Journal of Pharmaceutical Sciences, 73 (1), 43-47. doi: 10.1002/jps.2600730111

Fate of Chlorbutol During Storage in Polyethylene Dropper Containers and Simulated Patient Use

Holdsworth, DG, Roberts, MS and Polack, AE (1984). Fate of Chlorbutol During Storage in Polyethylene Dropper Containers and Simulated Patient Use. Journal of Clinical and Hospital Pharmacy, 9 (1), 29-39. doi: 10.1111/j.1365-2710.1984.tb00916.x

Inhibition of Platelet-Function by a Controlled Release Acetylsalicylic-Acid Formulation - Single and Chronic Dosing Studies

Roberts, MS, McLeod, LJ, Cossum, PA and Vial, JH (1984). Inhibition of Platelet-Function by a Controlled Release Acetylsalicylic-Acid Formulation - Single and Chronic Dosing Studies. European Journal of Clinical Pharmacology, 27 (1), 67-74. doi: 10.1007/BF02395209

Cyst and Host Tissue Concentrations of Mebendazole in Patients Undergoing Surgery for Hydatid-Disease

Braithwaite, PA, Allan, RJ, Dawson, M, Roberts, MS and Watson, TR (1983). Cyst and Host Tissue Concentrations of Mebendazole in Patients Undergoing Surgery for Hydatid-Disease. Medical Journal of Australia, 2 (8), 383-384.

Direct Quantitative-Determinations by Multiple Metastable Peak Monitoring .1. Warfarin in Plasma

Davies, NW, Bignall, JC and Roberts, MS (1983). Direct Quantitative-Determinations by Multiple Metastable Peak Monitoring .1. Warfarin in Plasma. Biomedical Mass Spectrometry, 10 (12), 646-651. doi: 10.1002/bms.1200101205

Drug Loss in Polyolefin Infusion Systems

Kowaluk, EA, Roberts, MS and Polack, AE (1983). Drug Loss in Polyolefin Infusion Systems. American Journal of Hospital Pharmacy, 40 (1), 118-119.

Factors Affecting the Availability of Diazepam Stored in Plastic Bags and Administered Through Intravenous Sets

Kowaluk, EA, Roberts, MS and Polack, AE (1983). Factors Affecting the Availability of Diazepam Stored in Plastic Bags and Administered Through Intravenous Sets. American Journal of Hospital Pharmacy, 40 (3), 417-423.

Factors Affecting the Availability of Organic Nitrates From Plastic Infusion Systems - Structure of Organic Nitrate, Nature of Plastic and Effect of Temperature

Roberts, MS, Cossum, PA, Kowaluk, EA and Polack, AE (1983). Factors Affecting the Availability of Organic Nitrates From Plastic Infusion Systems - Structure of Organic Nitrate, Nature of Plastic and Effect of Temperature. International Journal of Pharmaceutics, 17 (2-3), 145-159. doi: 10.1016/0378-5173(83)90028-5

Pharmacokinetics of Aspirin and Salicylate in Elderly Subjects and in Patients with Alcoholic Liver-Disease

Roberts, MS, Rumble, RH, Wanwimolruk, S, Thomas, D and Brooks, PM (1983). Pharmacokinetics of Aspirin and Salicylate in Elderly Subjects and in Patients with Alcoholic Liver-Disease. European Journal of Clinical Pharmacology, 25 (2), 253-261. doi: 10.1007/BF00543800

Clinical Pharmacokinetics of High-Dose Mebendazole in Patients Treated for Cystic Hydatid-Disease

Braithwaite, PA, Roberts, MS, Allan, RJ and Watson, TR (1982). Clinical Pharmacokinetics of High-Dose Mebendazole in Patients Treated for Cystic Hydatid-Disease. European Journal of Clinical Pharmacology, 22 (2), 161-169. doi: 10.1007/BF00542462

Interactions Between Drugs and Intravenous Delivery Systems

Kowaluk, EA, Roberts, MS and Polack, AE (1982). Interactions Between Drugs and Intravenous Delivery Systems. American Journal of Hospital Pharmacy, 39 (3), 460-467.

Topical Bioavailability of Methyl Salicylate

Roberts, MS, Favretto, WA, Meyer, A, Reckmann, M and Wongseelashote, T (1982). Topical Bioavailability of Methyl Salicylate. Australian and New Zealand Journal of Medicine, 12 (3), 303-305. doi: 10.1111/j.1445-5994.1982.tb02485.x

Availability of Isosorbide Dinitrate, Diazepam and Chlormethiazole, From IV Delivery Systems

Cossum, PA and Roberts, MS (1981). Availability of Isosorbide Dinitrate, Diazepam and Chlormethiazole, From IV Delivery Systems. European Journal of Clinical Pharmacology, 19 (3), 181-185. doi: 10.1007/BF00561946

Determination of Aspirin and its Major Metabolites in Plasma by High-Performance Liquid-Chromatography Without Solvent-Extraction

Rumble, RH, Roberts, MS and Wanwimolruk, S (1981). Determination of Aspirin and its Major Metabolites in Plasma by High-Performance Liquid-Chromatography Without Solvent-Extraction. Journal of Chromatography, 225 (1), 252-260. doi: 10.1016/S0378-4347(00)80270-4

Determination of Therapeutic Plasma-Concentrations of Tetrabenazine and An Active Metabolite by High-Performance Liquid-Chromatography

Roberts, MS, Watson, HM, McLean, S and Millingen, KS (1981). Determination of Therapeutic Plasma-Concentrations of Tetrabenazine and An Active Metabolite by High-Performance Liquid-Chromatography. Journal of Chromatography, 226 (1), 175-182. doi: 10.1016/S0378-4347(00)84218-8

Interactions Between Drugs and Polyvinyl-Chloride Infusion Bags

Kowaluk, EA, Roberts, MS, Blackburn, HD and Polack, AE (1981). Interactions Between Drugs and Polyvinyl-Chloride Infusion Bags. American Journal of Hospital Pharmacy, 38 (9), 1308-1314.

Pharmacists Tasks, Skills and Attributes - Their Professional Importance and Desirable Teaching Environment in the Australian State of Tasmania

Roberts, MS, Atkinson, JC, Cohen, P and Northcott, PH (1981). Pharmacists Tasks, Skills and Attributes - Their Professional Importance and Desirable Teaching Environment in the Australian State of Tasmania. Journal of Clinical and Hospital Pharmacy, 6 (1), 11-25. doi: 10.1111/j.1365-2710.1981.tb00883.x

Plastic Syringes and Intravenous Infusions

Roberts, MS, Cossum, PA, Kowaluk, EA, Polack, AE and Flukes, WK (1981). Plastic Syringes and Intravenous Infusions. Medical Journal of Australia, 2 (11), 580-581.

Stability of Nitroglycerin Ointment

Cossum, PA and Roberts, MS (1981). Stability of Nitroglycerin Ointment. Journal of Pharmaceutical Sciences, 70 (7), 832-833. doi: 10.1002/jps.2600700740

Effect of Posture and Sleep On Pharmacokinetics .1. Amoxycillin

Roberts, MS and Denton, MJ (1980). Effect of Posture and Sleep On Pharmacokinetics .1. Amoxycillin. European Journal of Clinical Pharmacology, 18 (2), 175-183. doi: 10.1007/BF00561587

Metabolism of Salicylate During Chronic Aspirin Therapy

Rumble, R. H., Brooks, P.M. and Roberts, M.S. (1980). Metabolism of Salicylate During Chronic Aspirin Therapy. British Journal of Clinical Pharmocology, 9 (1), 41-45. doi: 10.1111/j.1365-2125.1980.tb04794.x

The Availability of Nitroglycerin From Parenteral Solutions

Roberts, MS, Cossum, PA, Galbraith, AJ and Boyd, GW (1980). The Availability of Nitroglycerin From Parenteral Solutions. Journal of Pharmacy and Pharmacology, 32 (4), 237-244. doi: 10.1111/j.2042-7158.1980.tb12905.x

Ecotrin and Sra Clinical-Trial

Roberts, MS, Rumble, R, Gaiswinkler, J and Brooks, PM (1979). Ecotrin and Sra Clinical-Trial. Medical Journal of Australia, 1 (3), 92-92.

Interaction Between Levamisole and Aspirin in Man

Rumble, RH, Brooks, PM and Roberts, MS (1979). Interaction Between Levamisole and Aspirin in Man. British Journal of Clinical Pharmacology, 7 (6), 631-633. doi: 10.1111/j.1365-2125.1979.tb04657.x

Storage of Selected Substances in Aqueous-Solution in Polyethylene Containers - Effect of Some Physicochemical Factors On the Disappearance Kinetics of the Substances

Roberts, MS, Polack, AE, Martin, G and Blackburn, HD (1979). Storage of Selected Substances in Aqueous-Solution in Polyethylene Containers - Effect of Some Physicochemical Factors On the Disappearance Kinetics of the Substances. International Journal of Pharmaceutics, 2 (5-6), 295-306. doi: 10.1016/0378-5173(79)90036-X

Effect of Repeated Skin Application On Percutaneous Absorption of Salicylic-Acid

Roberts, MS and Horlock, E (1978). Effect of Repeated Skin Application On Percutaneous Absorption of Salicylic-Acid. Journal of Pharmaceutical Sciences, 67 (12), 1685-1687. doi: 10.1002/jps.2600671213

Loss of Nitroglycerin From Intravenous-Infusion Sets

Cossum, PA, Galbraith, AJ, Roberts, MS and Boyd, GW (1978). Loss of Nitroglycerin From Intravenous-Infusion Sets. Lancet, 2 (8085), 349-350.

Percutaneous Absorption of Phenolic Compounds - Mechanism of Diffusion Across Stratum-Corneum

Roberts, MS, Anderson, RA, Swarbrick, J and Moore, DE (1978). Percutaneous Absorption of Phenolic Compounds - Mechanism of Diffusion Across Stratum-Corneum. Journal of Pharmacy and Pharmacology, 30 (8), 486-490. doi: 10.1111/j.2042-7158.1978.tb13299.x

Pharmacokinetics of Sustained Release Aspirin

Brooks, P. M., Roberts, M. S. and Patel, P. (1978). Pharmacokinetics of Sustained Release Aspirin. British Journal of Clinical Pharmacy, 5 (4), 337-339.

Pharmacokinetics of Sustained-Release Aspirin

Brooks, PM, Roberts, MS and Patel, B (1978). Pharmacokinetics of Sustained-Release Aspirin. British Journal of Clinical Pharmacology, 5 (4), 337-339.

Preservation of Ophthalmic Solutions - Some Observations On Use of Chlorbutol in Plastic Containers

Blackburn, HD, Polack, AE and Roberts, MS (1978). Preservation of Ophthalmic Solutions - Some Observations On Use of Chlorbutol in Plastic Containers. Journal of Pharmacy and Pharmacology, 30 (10), 666-666. doi: 10.1111/j.2042-7158.1978.tb13358.x

Salivary Salicylate Secretion and Flow Rate

Roberts, M. S., Rumble, R. H. and Brooks, P. M. (1978). Salivary Salicylate Secretion and Flow Rate. British Journal of Clinical Pharmacy, 6.

Salivary Salicylate Secretion and Flow-Rate

Roberts, MS, Rumble, RH and Brooks, PM (1978). Salivary Salicylate Secretion and Flow-Rate. British Journal of Clinical Pharmacology, 6 (5), 429-429. doi: 10.1111/j.1365-2125.1978.tb04607.x

Permeability of Human Epidermis to Phenolic Compounds

Roberts, MS, Anderson, RA and Swarbrick, J (1977). Permeability of Human Epidermis to Phenolic Compounds. Journal of Pharmacy and Pharmacology, 29 (11), 677-683. doi: 10.1111/j.2042-7158.1977.tb11434.x

Percutaneous Absorption of Phenolic Compounds - Effect of Vehicles On Penetration of Phenol

Roberts, MS and Anderson, RA (1975). Percutaneous Absorption of Phenolic Compounds - Effect of Vehicles On Penetration of Phenol. Journal of Pharmacy and Pharmacology, 27 (8), 599-605. doi: 10.1111/j.2042-7158.1975.tb09513.x

Permeability of Solutes Through Biological-Membranes Measured by a Desorption Technique

Roberts, MS, Triggs, EJ and Anderson, RA (1975). Permeability of Solutes Through Biological-Membranes Measured by a Desorption Technique. Nature, 257 (5523), 225-227. doi: 10.1038/257225a0

Quantitative Prediction of Concentration Changes Due to Permeation of Solutes Through Polyethylene Containers During Autoclaving - a Preliminary Report

Polack, AE, Roberts, MS and Schumann, F (1970). Quantitative Prediction of Concentration Changes Due to Permeation of Solutes Through Polyethylene Containers During Autoclaving - a Preliminary Report. American Journal of Hospital Pharmacy, 27 (8), 638-&.

Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutes

Roberts, Michael S., Barkauskas, Deborah, Wang, Haolu, Liu, Xin, Studier, Hauke, Pastore, Michael, Zhang, Run, Holmes, Amy, Grice, Jeffrey E., Xu, Zhiping, Mohammed, Yousuf S. and Liang, Xiaowen (2020). Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutes. Multiphoton Microscopy in the Biomedical Sciences, San Francisco, CA United States, 2-4 February 2020. Bellingham, WA United States: SPIE. doi: 10.1117/12.2546058

In vivo toxicological evaluation of natural repellent in nanotechnological matrix

Andreo-Filho, N., Sales, C., Higushi, C., Haridass, I., Sanchez, W., Lopes, P., Grice, J., Roberts, M. and Leite-Silva, V. R. (2019). In vivo toxicological evaluation of natural repellent in nanotechnological matrix. 55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions, Helsinki Finland, Sep 08-11, 2019. CLARE: ELSEVIER IRELAND LTD.

PREVALENCE AND COMORBIDITIES ASSOCIATED WITH ANALGESIC PRESCRIBING FOR POLY-MEDICATED ELDERLY PATIENTS

Al-Qurain, A. A., Gebremedhin, L., Khan, M. S., Wiese, M. D., Williams, D. B., Mackenzie, L., Phillips, C., Russell, P. and Roberts, M. S. (2019). PREVALENCE AND COMORBIDITIES ASSOCIATED WITH ANALGESIC PRESCRIBING FOR POLY-MEDICATED ELDERLY PATIENTS. NEW YORK: ELSEVIER SCIENCE INC.

Characterizing and predicting the in vivo kinetics of mesenchymal stem cells and their secretome for the treatment of liver cirrhosis

Wang, H., Liang, X., Weijs, L., Brooks, A., Liu, X., Roberts, M. S. and Crawford, D. H. G. (2017). Characterizing and predicting the in vivo kinetics of mesenchymal stem cells and their secretome for the treatment of liver cirrhosis. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20–22 Aug 2017. Hoboken, NJ United States: Wiley.

In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe

Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2242978

Non-invasive assessment of the liver using imaging

Thorling (Thompson), Camilla, Wang, Haolu, Liu, Xin, Liang, Xiaowen, Crawford, Darrell H. G. and Roberts, Michael S. (2017). Non-invasive assessment of the liver using imaging. SPIE BioPhotonics Australasia Conference, Adelaide, SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: International Society for Optical Engineering. doi: 10.1117/12.2242883

Novel mechanistic imaging biomarkers for early prediction of acetaminophen-induced hepatotoxicity

Liang, X., Wang, H., Liu, X., Touraud, M., Chouane, J. B., Tse, B. and Roberts, M. S. (2017). Novel mechanistic imaging biomarkers for early prediction of acetaminophen-induced hepatotoxicity. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, , Gold Coast, Queensland, Australia, 20–22 Aug 2017. Richmond, VIC Australia: Wiley.

Quantitative optical imaging of paracetamol-induced metabolism changes in the liver

Liang, Xiaowen, Wang, Haolu, Liu, Xin and Roberts, Michael (2017). Quantitative optical imaging of paracetamol-induced metabolism changes in the liver. SPIE BioPhotonics Australasia, Adelaide, SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: International Society for Optical Engineering. doi: 10.1117/12.2242962

Improving Medicines Management at Patients Hospital Discharge

Gilbert, Alice V., Roberts, Michael S., Williams, Desmond B., Patel, Bhavini, Wallace, Joanna and Gilbert, Andrew L. (2016). Improving Medicines Management at Patients Hospital Discharge. HOBOKEN: WILEY-BLACKWELL.

Severe poisoning after ingestion of chloroform

Jayaweera, Dushan S., Islam, Shawkat A. K. M., Gunja, Naren, Cowie, Chris, Poojara, Latesh, Roberts, Michael S. and Isbister, Geoffrey K. (2016). Severe poisoning after ingestion of chloroform. ABINGDON: TAYLOR & FRANCIS LTD.

Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo

Thorling, Camilla A., Studier, Hauke, Crawford, Darrell H. G. and Roberts, Michael S. (2016). Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo. Multiphoton Microscopy in the Biomedical Sciences XVI, San Francisco, CA, United States, 14-16 February 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2235828

Isoniazid poisoning: pharmacokinetics and effect of dialysis after massive ingestion

Skinner, Kirsty, Saiao, Ana, Mustafa, Ahmed, Soderstrom, Jessica, Medley, Gregory, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Isoniazid poisoning: pharmacokinetics and effect of dialysis after massive ingestion. Unknown, Unknown, Unknown. New York, NY USA: Informa Healthcare.

A blood-flow limited physiologically based kinetic model to characterize and predict the biological fate of mesenchymal stem cells in vivo

Wang, H., Liang, X., Endo-Munoz, L., Weijs, L., Liu, X., Crawford, D. and Roberts, M. (2015). A blood-flow limited physiologically based kinetic model to characterize and predict the biological fate of mesenchymal stem cells in vivo. Gastro 2015 GESA‐AGW And WGO International Congress, Gastroenterological Society Of Australia Australian Gastroenterology Week 2015 - World Congress Of Gastroenterology, , Brisbane, Queensland, Australia, 28 September‐2 October 2015. Richmond, VIC Australia: Wiley.

A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo

Wang, H., Liang, X., Thorling, C., Xu, Z. P., Crawford, D., Liu, X. and Roberts, M. (2015). A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo. European Cancer Congress, Vienna, Austria, 2015. Hoboken, NJ United States: Wiley. doi: 10.1016/S0959-8049(15)30013-7

Can reporters of a medicine incident accurately reflect the clinical risk?

Gilbert, Alice V., Roberts, Michael, Williams, Des and Gilbert, Andrew L. (2015). Can reporters of a medicine incident accurately reflect the clinical risk?. 31st International Conference on Pharmacoepidemiology and Therapeutic Risk Management, Boston MA, USA, 22-26 August 2015. Oxford, United Kingdom: John Wiley & Sons.

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

Sime, F. B., Roberts, M., Tiong, I. S., Gardner, J., Lehman, S., Peake, S., Hahn, U., Warner, M. and Roberts, J. (2015). Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial. 20th Congress of European Hematology Association, Vienna, Austria, 11-14 June 2015. Pavia, Italy: Fondazione Ferrata Storti.

Early diagnosis of hepatocellular carcinoma by in vivo imaging

Liang, X., Wang, H., Zhu, Y., Grice, J., Liu, X., Xu, Z. and Roberts, M. (2015). Early diagnosis of hepatocellular carcinoma by in vivo imaging. European Cancer Congress, Vienna, Austria, 2015. Oxford, United Kingdom: Elsevier. doi: 10.1016/S0959-8049(16)30378-1

Evaluation of a rapid implementation quality improvement programme for medicine security

Gilbert, Alice V., Roberts, Michael, Williams, Des and Gilbert, Andrew Leigh (2015). Evaluation of a rapid implementation quality improvement programme for medicine security. 31st International Conference on Pharmacoepidemiology and Therapeutic Risk Management, Boston MA, USA, 22-26 August 2015. HOBOKEN: WILEY-BLACKWELL.

Hospital discharge medicines information: from trial to policy

Gilbert, Alice V., Roberts, Michael, Williams, Des and Gilbert, Andrew L. (2015). Hospital discharge medicines information: from trial to policy. 31st International Conference on Pharmacoepidemiology and Therapeutic Risk Management, Boston MA, USA, 22-26 August 2015. HOBOKEN: WILEY-BLACKWELL.

Severe but reversible toxicity with aldicarb ingestion

Michael, Adam, Mustafa, Ahmed, Medley, Gregory, Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Severe but reversible toxicity with aldicarb ingestion. XXXV International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT), St Julian's, Malta, 26–29 May, 2015. Philadelphia, United States: Taylor & Francis. doi: 10.3109/15563650.2015.1024953

Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis

Abdul-Aziz, M., Udy, A., Wallis, S., Roberts, M., Lipman, J. and Roberts, J. (2014). Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis. European Congress of Clinical Microbiology & Infectious Diseases, Barcelona, Spain, 10-13 May 2014.

A Toxicokinetic-Toxicodynamic Model for Paraquat in Humans

Musuamba, Flora T., Wunnapuk, Klintean, Mohammed, Fahim, Gawarammana, Indika, Verbeeck, Rorger K., Buckley, Nicholas A., Roberts, Michael S. and Wallemacq, Pierre (2013). A Toxicokinetic-Toxicodynamic Model for Paraquat in Humans. 13th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Salt Lake City Ut, Sep 22-26, 2013. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Removing nanoparticles from human skin

Lin, L. L., Sundh, D., Raphael, A. P., Roberts, M. S., Soyer, H. and Prow, T. W. (2012). Removing nanoparticles from human skin. Conjoint 3rd Australasian Wound & Tissue Repair Society and 9th Australasian Society for Dermatology Research Conference, Sydney, NSW, Australia, 22-24 May 2012. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/j.1524-475X.2012.00835.x

Effect of hepatic ischemia reperfusion injury on the function of P-Glycoprotein in transporting Rhodamine 123

Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M. and Roberts, Michael S. (2011). Effect of hepatic ischemia reperfusion injury on the function of P-Glycoprotein in transporting Rhodamine 123. 62nd Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA, United States, 04-08 November 2011.

Enhanced transdermal delivery of 5-aminolevulinic acid and a dipeptide by iontophoresis

Krishnan, Gayathri, Roberts, Michael S., Grice, Jeffrey, Anissimov, Yuri G. and Benson, Heather A. E. (2011). Enhanced transdermal delivery of 5-aminolevulinic acid and a dipeptide by iontophoresis. Hoboken NJ United States: John Wiley & Sons. doi: 10.1002/bip.21520

Simultaneous imaging of metal nanoparticle penetration and metabolic changes in human skin using fluorescence lifetime imaging

Prow, TW, Liu, D, Faye, R, Lin, LL, Grice, JE, Soyer, HP and Roberts, MS (2011). Simultaneous imaging of metal nanoparticle penetration and metabolic changes in human skin using fluorescence lifetime imaging. 38th Annual Meeting of the Society-for-Cutaneous-Ultrastructure-Research, Brisbane Australia, May 30-31, 2011. MALDEN: WILEY-BLACKWELL.

Drug structure-transport relationships

Roberts, Michael S. (2010). Drug structure-transport relationships. doi: 10.1007/s10928-010-9174-0

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin

Geusens, B., Van Gele, M., Braat, S., De Smedt, S. C., Stuart, M. C. A., Prow, T., Sanchez, W., Roberts, M. S., Sanders, N. N. and Lambert, J. (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin. 12th International Conference Perspectives in Percutaneous Penetration, La Grande Motte, France, 7‐10 April, 2010. Oxford, United Kingdom: John Wiley & Sons.

ZnO and TiO(2) particles: a study on nanosafety and photoprotection

Popov, Alexey, Zhao, Xin, Zvyagin, Andrei, Lademann, Jürgen, Roberts, Michael, Sanchez, Washington, Priezzhev, Alexander and Myllylä, Risto (2010). ZnO and TiO(2) particles: a study on nanosafety and photoprotection. SPIE Photonics Europe 2010. Biophotonics: Photonic Solutions for Better Health Care, Brussels, Belgium, 12-16 April, 2010. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.854561

Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin

Geusens, B., Braat, S., Stuart, M., De Smedt, S., Sanders, N., Prow, T., Roberts, M., Lambert, J. and Van Gele, M. (2009). Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin. 39th Annual European Society for Dermatological Research Meeting, Budapest, Hungary, 10 September 2009. London, United Kingdom: Nature Publishing Group.

Quantitation of stratum corneum depth in the skin surface biopsy by tape stripping

Grice, J. E., Stewart, L. and Roberts, M. S. (2009). Quantitation of stratum corneum depth in the skin surface biopsy by tape stripping. CSPS Symposium 2009: 12th Canadian Society for Pharmaceutical Sciences Annual Meeting, Toronto, ON, Canada, 3-6 June, 2009. Edmonton, AB, Canada: Canadian Society for Pharmaceutical Sciences.

Use of fluorescence lifetime imaging (FLIM) to measure skin biology and solute/nanoparticle transport in viable epidermis

Roberts, M.S., Sanchez, W. Jnr, Sanchez, W. Snr, Grice, J., Wu, M. and Prow, T. (2009). Use of fluorescence lifetime imaging (FLIM) to measure skin biology and solute/nanoparticle transport in viable epidermis. Light in Life Sciences Conference 2009, Melbourne, Australia, 24-27 November 2009.

Development and validation of RP-HPLC method for quantification of peptide dendrimers in skin permeation experiments

Mutalik, Srinivas, Parekh, Harendra S., Hewavitharana, Amitha K., Shaw, P. Nick, Anissimov, Yuri G. and Roberts, Michael S. (2008). Development and validation of RP-HPLC method for quantification of peptide dendrimers in skin permeation experiments. Australian Pharmaceutical Science Association Conference 2008, Canberra, ACT Australia, 6-9 December 2008.

Solute and vehicle lipophilicity effects on solute maximum flux through human epidermal membranes

Koda, Y., Cross, S. E., Grice, J. E., Jepps, O. G. and Roberts, M. S. (2008). Solute and vehicle lipophilicity effects on solute maximum flux through human epidermal membranes. Perspectives in Percutaneous Penetration Eleventh Annual Conference, La Grande Motte, France, 29 March, 2008.

Targeted Epidermal Delivery of Vaccines from Coated Micro-Nanoprojection Patches

Tarl Prow, Xianfeng Chen, Michael Crichton, Yash Tiwari, Francesca Gradassi, Kristin Raphaelli, Mahony, Donna, Fernando, Germain J., Roberts, Michael S. and Kendall, Mark A. (2008). Targeted Epidermal Delivery of Vaccines from Coated Micro-Nanoprojection Patches. International Conference of Nanoscience and Nanotechnology, Melbourne, Australia, February 25-29, 2008. New York , U.S.A.: IEEE. doi: 10.1109/ICONN.2008.4639262

The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats

Cross, Sheree, Dalley, Andrew, Lipman, Jeffery, Ranasinghe, Kanchanamala, Roberts, Michael, Robertson, Thomas and Venkatesh, Bala (2008). The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats. 14th Congress of the International Society for Burn Injuries, Montreal, Canada, 7-11 September 2008.

The effect of thermal injury on interstitial tissue antibiotic distribution and the choice of resuscitation fluid

Cross, Sheree, Dalley, Andrew, Kanchanamala, Ranasinghe, Lipman, Jeffery, Roberts, Michael, Robertson, Thomas and Venkatesh, Bala (2008). The effect of thermal injury on interstitial tissue antibiotic distribution and the choice of resuscitation fluid. Australian Health and Medical Research Congress (AHMRC) 2008, Brisbane, Australia, 16-21 November 2008.

Pharmacokinetics of Digoxin Cross-Reacting Substances in Patients With Acute Yellow Oleander (Thevetia peruviana) Poisoning, Including the Effect of Activated Charcoal

Roberts, D. M., Southcott, E., Potter, J. M., Roberts, M. S., Eddleston, M. and Buckley, N. A. (2006). Pharmacokinetics of Digoxin Cross-Reacting Substances in Patients With Acute Yellow Oleander (Thevetia peruviana) Poisoning, Including the Effect of Activated Charcoal. Philadelphia: Lippincott Williams & Wilkins. doi: 10.1097/FTD.0b013e31802bfd69

The relative roles of intercellular lipids and corneocytes in hydrocortisone transport in human stratum corneum

Grice, J. E., Anissimov, Y. G., Cross, S. E. and Roberts, M. S. (2006). The relative roles of intercellular lipids and corneocytes in hydrocortisone transport in human stratum corneum. 10th Annual Perspectives in Percutaneous Penetration Conference, La Grande Motte, France, 18-20 April 2006.

Hypercapnic acidosis following hypoxia in newborn piglet, a potential neuroprotectant

Bjorkman, S. T., O'Driscoll, S. M., Burke, C., Roberts, M. S. and Colditz, P. B. (2005). Hypercapnic acidosis following hypoxia in newborn piglet, a potential neuroprotectant. Royal Brisbane and Women's Hospital (RBWH) Health Care Symposium, Brisbane, 24-28 October 2005.

Risk factors and assessment methods for depression associated with Parkinson's disease

Dissanayaka, N. N. W., Deng, Y., Marsh, R., O’Sullivan, J. D., Silburn, P. A., Roberts, M. and Mellick, G. D. (2005). Risk factors and assessment methods for depression associated with Parkinson's disease. ASMR Queensland Postgraduate Medical Research Student Conference, Brisbane, QLD, Australia, 10 June, 2005.

Hypercapnic acidosis following hypoxia in newborn piglet, a potential neuroprotectant?

Bjorkman, S. T., O'Driscoll, S. M., Burke, C., Roberts, M. S. and Colditz, P. B. (2004). Hypercapnic acidosis following hypoxia in newborn piglet, a potential neuroprotectant?. 20th Biennial Meeting of the International-Society-for-Neurochemistry/European-Society-for-Neurochemistry, Innsbruck, Austria, 21-26 August, 2005. Oxford: Blackwell. doi: 10.1111/j.1474-1644.2005.03322.x

Increased platelet-derived microparticles in the coronary circulation of patients undergoing coronary angioplasty

Craft, JA, Masci, PP, Roberts, MS, Brighton, TA, Garrahy, P, Cox, S and Marsh, NA (2004). Increased platelet-derived microparticles in the coronary circulation of patients undergoing coronary angioplasty. 2004 ISHR World Congress, Brisbane, Qld Australia, 7-11 Aug 2004. London: Academic Press Ltd Elsevier Science Ltd. doi: 10.1016/j.yjmcc.2004.05.002

Optical fibre probe for microdialysis

Verhaege, A., Heng Ng, C., Zvyagin, A. V., Anissimov, Y. and Roberts, M. S. (2004). Optical fibre probe for microdialysis. The Australian Conference on Optical Fibre Technology, Canberra, 5-8 July, 2004. Canberra: The Australian National University.

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia

Bridle, K. R., Fletcher, L. M., Murphy, T., Walters, M., Hung, D., Chang, P., Siebert, G., Roberts, M. and Crawford, D. H. G. (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24-28 October 2003. Carlton South, Vic.: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia

Fletcher,Linda, Bridle, Kim, Murphy, Therese, Walters, Margaret, Hung, Daniel, Chang, Ping, Siebert, Gerhard, Roberts, Michael and Crawford, Darrell (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24 - 28 October, 2003. Hoboken, NJ, U.S.A: Wiley Interscience. doi: 10.1002/hep.1840380508

Are oils used as laxatives in cosmetics or skin care a trigger for arthritis?

Whitehouse, M. W. and Roberts, M. S. (2001). Are oils used as laxatives in cosmetics or skin care a trigger for arthritis?. IXth International Congress of Toxicology, Brisbane, 8-12 July 2001. Ireland: Elsevier Science Ireland Ltd.

Domiciliary medication reviews: Description of the trialled model and results

Sorensen, L. and Roberts, M. S. (2001). Domiciliary medication reviews: Description of the trialled model and results. Annual Scientific Meeting of the ASCEPT, Dunedin, NZ, 3-5 Dec 2001. Australia: Aust Soc of Clin. & Exp. Pharmacol. & Toxic..

Economic evaluation of a coordinated care program in Australia

Grobler, M, Stokes, J. A., Watts, I. and Roberts, M. S. (2001). Economic evaluation of a coordinated care program in Australia. International Health Economic Association, York, England, July 2001. UK:

Improving medication use in the Australian community: Using indicators for evaluation

Sorensen, L., Stokes, J. A. and Roberts, M. S. (2001). Improving medication use in the Australian community: Using indicators for evaluation. 5th Congress of the Eur. Assoc. for Clinical Pharmacology & Ther., Odense, Denmark, 12-15 Sept 2001. Copenhagen: Munksgaard.

Pharmacokinetic implications of hepatic transporter events

Roberts, M. S. (2001). Pharmacokinetic implications of hepatic transporter events. Annual Scientific Meeting of ASCEPT, Dunedin, NZ, 3-5 Dec 2001. Australia: Australasian Soc of Clin & Exper Pharmac. & Toxic..

Translation of quality use of medicines research into practice in residential and community care settings

Stokes, J. A. and Roberts, M. S. (2001). Translation of quality use of medicines research into practice in residential and community care settings. Inaugural Qld Health & Medical Scientific Meeting, Brisbane, 4 Dec 2001.

Antioxidant activity of celery seed extracts

Whitehouse, M. W., Hung, D. Y., Cheung, K. and Roberts, M. S. (2000). Antioxidant activity of celery seed extracts. Annual Scientific Meeting of A.S.C.E.P.T, Newcastle, Australia, 3-6 Dec 2000. Sydney, Australia: ASCEPT.

Medication misadventure risks - findings at home visits

Sorensen, L., Stokes, J. A., Woodward, M. and Roberts, M. S. (2000). Medication misadventure risks - findings at home visits. Annual Scientific Meeting of ASCEPT, Newcastle, Australia, 3-6 Dec 2000. Sydney, Australia: ASCEPT.

Modelling distribution kinetics of drugs in the rat head

Foster, K., Weiss, M. and Roberts, M. S. (2000). Modelling distribution kinetics of drugs in the rat head. Annual Scientific Meeting of ASCEPT, Newcastle, NSW, 3-6 Dec 2000. Sydney, Australia: ASCEPT.

Multidisciplinary case conference reviews: improving outcomes for nursing home residents, carers and health professionals

King, M. A. and Roberts, M. S. (2000). Multidisciplinary case conference reviews: improving outcomes for nursing home residents, carers and health professionals. United Kingdom Clinical Pharmacy Association., Leeds, UK, 19-21 May 2000. Leeds, England: University Print Services.

Risk adjustment in evaluating outcomes in coordinated care

Stokes, J. A., Grobler, M. P., Watts, I. T. and Roberts, M. S. (2000). Risk adjustment in evaluating outcomes in coordinated care. Annual Scientific Meeting of ASCEPT, Newcastle, NSW, 3-6 Dec 2000. Sydney, Australia: ASCEPT.

The effect of hepatectomy on the healing of full-thickness of excisional wounds in rats

Cross, S. E. and Roberts, M. S. (2000). The effect of hepatectomy on the healing of full-thickness of excisional wounds in rats. Annual Scientific Meeting of the A.S.C.E.P.T, Newcastle, Australia, 3-6 Dec 2000. Sydney, Australia: ASCEPT.

The effect of occlusion on the epidermal penetration of parabens from a commercial allergy test ointment, acetone and ethanol vehicles

Cross, S. E. and Roberts, M. S. (2000). The effect of occlusion on the epidermal penetration of parabens from a commercial allergy test ointment, acetone and ethanol vehicles. 7th International PPP Conference, La Grande Motte, France, 25-29 April 2000. Cardiff, UK: STS Publishing.

The release of lipophilic agents from formulations and solutions through permeable membranes

Hayden, C. G., Warnholtz, C. R., Cross, S. E., Benson, H. A. and Roberts, M. S. (2000). The release of lipophilic agents from formulations and solutions through permeable membranes. 7th International PPP Conference, La Grande Motte, France, 25-29 April 2000. Cardiff, UK: STS Publishing.

The use of finite dose data to predict transdermal absorption parameters

Anissimov, Y., Cross, S. E. and Roberts, M. S. (2000). The use of finite dose data to predict transdermal absorption parameters. 7th International PPP Conference, La Grande Motte, France, 25-29 April 2000. Cardiff, UK: STS Publishing.

Common vehicle components effects on flux of 3H water and 14C phenol through human epidermis

Rosado, C., Cross, S. E., Pugh, J., Hadgraft, J. and Roberts, M. S. (1999). Common vehicle components effects on flux of 3H water and 14C phenol through human epidermis. 33rd Annual Scientific Meeting of ASCEPT, Sydney, Australia, 4 - 8 December, 1999. Melbourne, Vic.: ASCEPT.

Cytotoxic iontophoresis

Macfarlane, B., Benson, H. A. and Roberts, M. S. (1999). Cytotoxic iontophoresis. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: ASCEPT.

Effect of gender and pregnancy on palmitate transport in the isolated perfused rat liver

Mills, P. C., Dorissi, T., Anissimov, Y. and Roberts, M. S. (1999). Effect of gender and pregnancy on palmitate transport in the isolated perfused rat liver. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: ASCEPT.

Evaluation of the transfer of quality use of medicines research into practice in residential aged care

Stokes, J. A. and Roberts, M. S. (1999). Evaluation of the transfer of quality use of medicines research into practice in residential aged care. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

In vitro penetrations of solutes through human skin and polyethylene membranes: The effect of sampling rate. A solubiliser, and increased static diffusion layer

Hayden, C. G., Cross, S. E., Benson, H. A. and Roberts, M. S. (1999). In vitro penetrations of solutes through human skin and polyethylene membranes: The effect of sampling rate. A solubiliser, and increased static diffusion layer. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: ASCEPT.

Influence of emulsion viscosity with infinite and finite dosing on the penetration of benzophenone-3 through human epidermal and polyethylene membranes

Cross, S. E., Jiang, R., Benson, H. A. and Roberts, M. S. (1999). Influence of emulsion viscosity with infinite and finite dosing on the penetration of benzophenone-3 through human epidermal and polyethylene membranes. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

Medication reviews and discharge counselling of veterans in Private Hospitals

Sorensen, L. and Roberts, M. S. (1999). Medication reviews and discharge counselling of veterans in Private Hospitals. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney: Australasian Society of Clinical & Experimental Pharmacologis.

The extended convection-dispersion model of organ distribution kinetics

Roberts, M. S. and Anissimov, Y. (1999). The extended convection-dispersion model of organ distribution kinetics. 33rd Annual Scientific Meeting of ASCEPT, Sydney, 4-8 Dec, 1999. Sydney, Australia: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

The pharmacokinetics of 14C- flunitrazepam and 3H- propranolol in the rat head using in-situ and invivo models

Foster, K. and Roberts, M. S. (1999). The pharmacokinetics of 14C- flunitrazepam and 3H- propranolol in the rat head using in-situ and invivo models. 33rd Annual Scientific Meeting of ASCEPT, Sydney, Australia, 4-8 Dec, 1999. Sydney, Australia: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

The release of lipophilic agents from formulations and solutions through permeable membranes

Warnholtz, C. R., Hayden, C. G., Cross, S. E., Benson, H. A. and Roberts, M. S. (1999). The release of lipophilic agents from formulations and solutions through permeable membranes. 33rd Annual Scientific Meeting of ASCEPT, Sydney, Australia, 4-8 Dec, 1999. Sydney, Australia: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

The use of finite dose data to predict transdermal absorption parameters

Anissimov, Y., Cross, S. E. and Roberts, M. S. (1999). The use of finite dose data to predict transdermal absorption parameters. 33rd Annual Scientific Meeting of ASCEPT, Sydney, Australia, 4-8 Dec, 1999. Sydney, Australia: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

Transdermal Iontophoresis - Role of the Stratum-Corneum and Epidermis in Solute Transport

Cross, SE and Roberts, MS (1994). Transdermal Iontophoresis - Role of the Stratum-Corneum and Epidermis in Solute Transport. BASINGSTOKE: STOCKTON PRESS.

A case study in organisational development: quality of medication care project

Roberts, M. (1994). A case study in organisational development: quality of medication care project. The University of Queensland: