Associate Professor Johan Rosengren

Principal Research Fellow

School of Biomedical Sciences
Faculty of Medicine

Affiliate Senior Research Fellow

Institute for Molecular Bioscience
j.rosengren@uq.edu.au
+61 7 336 51403

Overview

Dr Rosengren is an ARC Future Fellow at the School of Biomedical Sciences, University of Queensland. He completed his PhD, which focused on structure-activity relationships of antimicrobial peptides, under the supervision of Professor David Craik at the Institute for Molecular Bioscience, UQ, in 2003. After two years of post-doctoral work at IMB he moved to Sweden in 2005 to take up a position as Assistant Professor at Linnaeus University, Kalmar. During 2008-2009 he held a joint appointment between Linnaeus University and Uppsala University. In 2009 he was awarded the Swedish “Docent” title before returning to University of Queensland as a Senior Research Officer, funded by an NHMRC Career Development Award and an ARC Future Fellowship. Dr Rosengren’s research focuses on structure activity relationships of bioactive peptides, in particular peptide hormones and the use of NMR spectroscopy in the design of novel peptide drug leads.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Master of Biomedical Chemistry, University of Kalmar

Publications

View all Publications

Supervision

View all Supervision

Publications

Book Chapter

  • Schroeder, Christina I. and Rosengren, K. Johan (2020). Three-dimensional structure determination of peptides using solution nuclear magnetic resonance spectroscopy. Snake and spider toxins: methods and protocols. (pp. 129-162) New York, NY USA: Humana Press. doi: 10.1007/978-1-4939-9845-6_7

  • Daly, Norelle L. and Rosengren, K. Johan (2015). Structural studies of cyclotides. Plant cyclotides. (pp. 155-186) edited by David Craik. Cambridge, MA, United States: Academic Press. doi: 10.1016/bs.abr.2015.09.003

  • Rosengren, K. Johan, Daly, N. L. and Craik, D. J. (2009). NMR of peptide toxins. Annual reports on NMR Spectroscopy. (pp. 89-147) edited by Graham A. Webb. Oxford England U.K.: Academic Press Elsevier. doi: 10.1016/S0066-4103(09)06802-1

Journal Article

Conference Publication

  • Johnstone, E. K., See, H. B., Abhayawardana, R. S., Song, A., Rosengren, K. J., Hill, S. J. and Pfleger, K. D. (2019). Detection and characterisation of GPCR heteromers using NanoBRET ligand binding. British-Pharmacology-Society Meeting (Pharmacology), London, United Kingdom, 18-20 December 2018. Oxford, United Kingdom: John Wiley & Sons .

  • Zhao, Tianjiao, Rosengren, K. Johan, Cardoso, Fernanda C. and Lewis, Richard J. (2019). Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019.

  • Jacobsson, E., Andersson, H. S., Strand, M., Lebbe, E., Eriksson, C., Peigneur, S., Rosengren, J., Tytgat, J. and Goransson, U. (2016). Peptide toxins from the longest animal on earth. 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen Denmark, Jul 24-27, 2016. STUTTGART: GEORG THIEME VERLAG KG. doi: 10.1055/s-0036-1596160

  • Andersson, H. S., Jacobsson, E., Eriksson, C., Hedstrom, M., Seth, H., Sundberg, P., Rosengren, K. J., Strand, M. and Goransson, U. (2016). The toxicity of ribbon worms: Alpha-nemertides or tetrodotoxin, or both?. 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen Denmark, Jul 24-27, 2016. STUTTGART: GEORG THIEME VERLAG KG. doi: 10.1055/s-0036-1596617

  • Hojo, K., Hossain, M. A., Rosengren, K. J., Ma, S., Gundlach, A. L., Tsuda, Y., Hidaka, K., Bathgate, R. A. and Wade, J. D. (2016). Design, synthesis and biological activity of hydrocarbon stapled single-chain relaxin-3 analogue. 34th European Peptide Symposium and 8th International Peptide Symposium, Leipzig, Germany, 4-9 September 2016. Oxford, United Kingdom: John Wiley & Sons.

  • Goncalves, Daniela, Rishi, Gautam, Aliyanto, Randy, Rosengren, Johan, Subramaniam, Nathan, Frazer, David and Clark, Richard (2016). Development of peptide therapeutics for iron disorders. 6th Meeting of the International BioIron Society, Zhejiang University, Hangzhou, China, 8-10 September 2015. Hoboken, NJ, United States: John Wiley & Sons.

  • Franke, B., James, A., Mobli, M., Mylne, J. S. and Rosengren, K. J. (2016). Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage Protein. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Wiley.

  • Cardoso, F. C., Dekan, Z., Anangi, R., Rosengren, K. J., Erickson, A., Vetter, I., Herzig, V., Alewood, P., King, G. F. and Lewis, R. J. (2014). Discovery of voltage-gated sodium channel inhibitors from tarantula venoms. Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, 19-23 October 2014.

  • Brust, A., Gori, A., Wang, C-I A., Harvey, P. J., Rosengren, K. J., Gelmi, M. L., Longh, R., Lewis, R. J. and Alewood, P. F. (2014). SELECTIVE FOLDING AND STABILIZATION OF A CYSTEINE RICH CONOTOXIN, MrIA AS A 1,2,3-TRIAZOLE-DISULFIDE BOND HYBRID. 33rd European Peptide Symposium, Sofia, Bulgaria, 31 August – 5 September 2014. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2687

  • Rosengren, K. J., Elliott, A. G., Franke, B. and Mylne, J. S. (2014). Structural Diversity of a Novel Family of Cyclic Plant Peptides. 33rd European Peptide Symposium, Sofia Bulgaria, August 31 – September 5 2014. United Kingdom: John Wiley & Sons.

  • Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

  • Ragnarsson, Lotten, Wang, Ching-I. Anderson, Andersson, Åsa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2012). The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.137

  • Henriques, Sonia Troeira, Huang, Yen-Boa, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Second, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, I. David J. (2011). Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions. 22nd American Peptide Symposium, San Diego, California, 25-30 June 2011 . Hoboken, NJ, United States: John Wiley & Sons.

  • Haugaard-Kedstrom, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Craik, D. J., Wade, J. D. and Rosengren, K. J. (2010). Characterisation of the human INSL5 solution structure. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303

  • Manuel Plan, Rosengren, K. Johan, Sando, Lillian, Daly, Norelle L. and Craik, David J. (2010). Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October 2009. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.21409

  • Haugaard-Kedström, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Wade, J. D., Craik, D. J. and Rosengren, K. J. (2010). Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1301

  • Daly, Norelle L., Chen, Yi K., Rosengren, K. Johan, Marx, Ute C., Phillips, Martin L., Waring, Alan J., Wang, Wei, Lehrer, Robert I. and Craik, Robert I. (2009). Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007. New York, United States: Springer New York LLC. doi: 10.1007/978-0-387-73657-0_254

  • Rosengren, K. Johan, Bathgate, Ross A. D., Craik, David J., Daly, Norelle L., Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter and Wade, John D. (2009). Structural insights into the function of relaxins. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2009.03833.x

  • Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2009). Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2008.03805.x

  • Craik, David J., Rosengren, K. Johan, Sando, Lillian and Simonsen, Shane S. (2006). Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_101

  • Rosengren, KJ, Jen, FEC, Clark, RJ, Goransson, U, Daly, NL and Craik, DJ (2005). A novel threaded ring structure for the antimicrobial peptide microcin J25. Peptides 2004: 3rd International Peptide Symposium / 28th European Peptide Symposium, Prague, Czech Republic, 5 - 10 September 2004. Geneva, Switzerland: Kenes International.

  • Craik, D. J., Rosengren, K. J., Clark, R. J., Daly, N. L. and Goransson, U. (2004). A novel threaded ring structure for the antimicrobial peptide microcin J25. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.617

  • Plan, MR, Goransson, U, Rosengren, KJ, Clark, RJ, Daly, NL, Evert, P, Chen, C, Cagauan, AG and Craik, DJ (2004). Cyclotides: Novel Peptidic Pesticides for Plant Protection. CHICHESTER: JOHN WILEY & SONS LTD.

  • Clark, RJ, Dempster, L, Daly, NL, Rosengren, KJ and Craik, DJ (2004). Design, Synthesis and Structural Studies of Cyclic Alpha-Conotoxins. CHICHESTER: JOHN WILEY & SONS LTD.

  • Craik, David J., Daly, Norelle L., Colgrave, Michelle L. and Rosengren, K. Johan (2004). Discovery and applications of the cyclotides: Circular proteins from plants. 18th American Peptide Symposium, Boston, MA, U.S.A., 19-23 July 2003. Washington, DC, USA: American Chemical Society.

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision