Dr Fleur Garton

NHMRC ECR Fellow

Institute for Molecular Bioscience

Affil Postdoc Research Fellow

Queensland Brain Institute
f.garton@imb.uq.edu.au
+61 7 334 66408

Overview

Fleur Garton completed a Bachelor of Applied Science (Sports and Exercise Science) in 2008 at the University of Sydney. Pursing an interest in the molecular basis of skeletal muscle function she completed her honours and PhD at the Institute of Neuroscience and Muscle research at the Children’s Hospital Westmead. Here, she was part of Professor Kathryn North’s team looking at the molecular mechanisms of ACTN3, the “gene for speed,” on muscle adaptation. Fleur remained with the team as post-doctoral researcher and spent two years at the Murdoch Childrens Research Institute, Melbourne. She was responsible for modelling the effect of gene dosage using rAAV vectors while helping to build the Athlome Project Consortium to understand the mechanistic extremes of performance and health. In 2016, Fleur was awarded a Bill Gole MND Postdoctoral fellowship from MNDRIA to join the team at CNSG. Focussed on the mechanisms of motor neurone disease, the project will pursue rapid improvements in diagnosis and treatments through the use of novel genomics analyses and patient disease models.

Research Interests

  • Motor Neurone Disease
  • Genetic variants influencing performance
  • Neuromuscular Disease

Qualifications

  • Doctor of Philosophy, The University of Sydney

Publications

  • Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, McCann, Emily P., Mowry, Bryan J., Ngo, Shyuan T., Pamphlett, Roger, Ran, Shu, Reutens, David C., Rowe, Dominic B., Sachdev, Perminder, Shah, Sonia, Song, Sharon, Tan, Li-Jun, Tang, Lu, van den Berg, Leonard H., van Rheenen, Wouter, Veldink, Jan H., Wallace, Robyn H., Wheeler, Lawrie, Williams, Kelly L., Wu, Jinyu, Wu, Xin, Yang, Jian, Yue, Weihua, Zhang, Zong-Hong, Zhang, Dai, Noakes, Peter G., Blair, Ian P., Henderson, Robert D., McCombe, Pamela A., Visscher, Peter M., Xu, Huji, Bartlett, Perry F., Brown, Matthew A., Wray, Naomi R. and Fan, Dongsheng (2017) Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 1: . doi:10.1038/s41467-017-00471-1

  • Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben, Brage, Soren, Cheng, Yu-Ching, Cieszczyk, Pawel, Derave, Wim, Eriksson, Karl-Fredrik, Eynon, Nir, Linneberg, Allan, Lucia, Alejandro, Massidda, Myosotis, Mitchell, Braxton D., Miyachi, Motohiko, Murakami, Haruka, Padmanabhan, Sandosh, Pandey, Ashutosh, Papadimitriou, Loannis, Rajpal, Deepak K., Sale, Craig, Schnurr, Theresia M., Sessa, Francesco, Shrine, Nick, Tobin, Martin D., Varley, Ian, Wain, Louise V., Wray, Naomi R., Lindgren, Cecilia M., MacArthur, Daniel G., Waterworth, Dawn M., McCarthy, Mark I., Pedersen, Oluf, Khaw, Kay-Tee, Kie, Douglas P., Pitsiladis, Yannis, Fuku, Noriyuki, Franks, Paul W., North, Kathryn N., van Duijn, Cornelia M., Mather, Karen A., Hansen, Torben, Hansson, Ola, Spector, Tim, Murabito, Joanne M., Richards, J. Brent, Rivadeneira, Fernando, Langenberg, Claudia, Perry, John R. B., Wareham, Nick J., Scott, Robert A., GEFOS Any-Type of Fracture Consortium, Oei, Ling, Zheng, Hou-Feng, Forgetta, Vincenzo, Leong, Aaron, Ahmad, Omar S., Laurin, Charles, Mokry, Lauren E., Ross, Stephanie, Elks, Cathy E., Bowden, Jack, Warrington, Nicole M., Murray, Anna, Ruth, Katherine S., Tsilidis, Konstantinos K., Medina-Gomez, Carolina, Estrada, Karol, Bis, Joshua C., Chasman, Daniel I., Demissie, Serkalem, Enneman, Anke W., Hsu, Yi-Hsiang, Ingvarsson, Thorvaldur, Kaehoenen, Mika, Kammerer, Candace, Lacroix, Andrea Z., Li, Guo, Liu, Ching-Ti, Liu, Yongmei, Lorentzon, Mattias, Maegi, Reedik, Mihailov, Evelin, Milani, Lili, Moayyeri, Alireza, Nielson, Carrie M., Sham, Pack Chung, Siggeirsdotir, Kristin, Sigurdsson, Gunnar, Stefansson, Kari, Trompet, Stella, Thorleifsson, Gudmar, Vandenput, Liesbeth, van der Velde, Nathalie, Viikari, Jorma, Xiao, Su-Mei, Zhao, Jing Hua, Evans, Daniel S, Cummings, Steven R., Cauley, Jane, Duncan, Emma L., de Groot, Lisette C. P. G. M., Esko, Tonu, Gudnason, Vilmundar, Harris, Tamara B., Jackson, Rebecca D., Jukema, J. Wouter, Ikram, Arfan M. A., Karasik, David, Kaptoge, Stephen, Kung, Annie Wai Chee, Lehtimaeki, Terho, Lyytikaeinen, Leo-Pekka, Lips, Paul, Luben, Robert, Metspalu, Andres, van Meurs, Joyce B. J., Minster, Ryan L., Orwoll, Erick, Oei, Edwin, Psaty, Bruce M., Raitakari, Olli T., Ralston, Stuart W., Ridker, Paul M., Robbins, John A., Smith, Albert V., Styrkarsdottir, Unnur, Tranah, Gregory J., Thorstensdottir, Unnur, Uitterlinden, Andre G., Zmuda, Joseph, Zillikens, M. Carola, Ntzani, Evangelia E., Evangelou, Evangelos, Ioannidis, John P. A., Evans, David M. and Ohlsson, Claes (2017) Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8 . doi:10.1038/ncomms16015

  • Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017) Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 4: 418-428. doi:10.1002/mgg3.302

View all Publications

Publications

Journal Article

  • Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, McCann, Emily P., Mowry, Bryan J., Ngo, Shyuan T., Pamphlett, Roger, Ran, Shu, Reutens, David C., Rowe, Dominic B., Sachdev, Perminder, Shah, Sonia, Song, Sharon, Tan, Li-Jun, Tang, Lu, van den Berg, Leonard H., van Rheenen, Wouter, Veldink, Jan H., Wallace, Robyn H., Wheeler, Lawrie, Williams, Kelly L., Wu, Jinyu, Wu, Xin, Yang, Jian, Yue, Weihua, Zhang, Zong-Hong, Zhang, Dai, Noakes, Peter G., Blair, Ian P., Henderson, Robert D., McCombe, Pamela A., Visscher, Peter M., Xu, Huji, Bartlett, Perry F., Brown, Matthew A., Wray, Naomi R. and Fan, Dongsheng (2017) Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 1: . doi:10.1038/s41467-017-00471-1

  • Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben, Brage, Soren, Cheng, Yu-Ching, Cieszczyk, Pawel, Derave, Wim, Eriksson, Karl-Fredrik, Eynon, Nir, Linneberg, Allan, Lucia, Alejandro, Massidda, Myosotis, Mitchell, Braxton D., Miyachi, Motohiko, Murakami, Haruka, Padmanabhan, Sandosh, Pandey, Ashutosh, Papadimitriou, Loannis, Rajpal, Deepak K., Sale, Craig, Schnurr, Theresia M., Sessa, Francesco, Shrine, Nick, Tobin, Martin D., Varley, Ian, Wain, Louise V., Wray, Naomi R., Lindgren, Cecilia M., MacArthur, Daniel G., Waterworth, Dawn M., McCarthy, Mark I., Pedersen, Oluf, Khaw, Kay-Tee, Kie, Douglas P., Pitsiladis, Yannis, Fuku, Noriyuki, Franks, Paul W., North, Kathryn N., van Duijn, Cornelia M., Mather, Karen A., Hansen, Torben, Hansson, Ola, Spector, Tim, Murabito, Joanne M., Richards, J. Brent, Rivadeneira, Fernando, Langenberg, Claudia, Perry, John R. B., Wareham, Nick J., Scott, Robert A., GEFOS Any-Type of Fracture Consortium, Oei, Ling, Zheng, Hou-Feng, Forgetta, Vincenzo, Leong, Aaron, Ahmad, Omar S., Laurin, Charles, Mokry, Lauren E., Ross, Stephanie, Elks, Cathy E., Bowden, Jack, Warrington, Nicole M., Murray, Anna, Ruth, Katherine S., Tsilidis, Konstantinos K., Medina-Gomez, Carolina, Estrada, Karol, Bis, Joshua C., Chasman, Daniel I., Demissie, Serkalem, Enneman, Anke W., Hsu, Yi-Hsiang, Ingvarsson, Thorvaldur, Kaehoenen, Mika, Kammerer, Candace, Lacroix, Andrea Z., Li, Guo, Liu, Ching-Ti, Liu, Yongmei, Lorentzon, Mattias, Maegi, Reedik, Mihailov, Evelin, Milani, Lili, Moayyeri, Alireza, Nielson, Carrie M., Sham, Pack Chung, Siggeirsdotir, Kristin, Sigurdsson, Gunnar, Stefansson, Kari, Trompet, Stella, Thorleifsson, Gudmar, Vandenput, Liesbeth, van der Velde, Nathalie, Viikari, Jorma, Xiao, Su-Mei, Zhao, Jing Hua, Evans, Daniel S, Cummings, Steven R., Cauley, Jane, Duncan, Emma L., de Groot, Lisette C. P. G. M., Esko, Tonu, Gudnason, Vilmundar, Harris, Tamara B., Jackson, Rebecca D., Jukema, J. Wouter, Ikram, Arfan M. A., Karasik, David, Kaptoge, Stephen, Kung, Annie Wai Chee, Lehtimaeki, Terho, Lyytikaeinen, Leo-Pekka, Lips, Paul, Luben, Robert, Metspalu, Andres, van Meurs, Joyce B. J., Minster, Ryan L., Orwoll, Erick, Oei, Edwin, Psaty, Bruce M., Raitakari, Olli T., Ralston, Stuart W., Ridker, Paul M., Robbins, John A., Smith, Albert V., Styrkarsdottir, Unnur, Tranah, Gregory J., Thorstensdottir, Unnur, Uitterlinden, Andre G., Zmuda, Joseph, Zillikens, M. Carola, Ntzani, Evangelia E., Evangelou, Evangelos, Ioannidis, John P. A., Evans, David M. and Ohlsson, Claes (2017) Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8 . doi:10.1038/ncomms16015

  • Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017) Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 4: 418-428. doi:10.1002/mgg3.302

  • Garton, Fleur C., North, Kathryn N., Koch, Lauren G., Britton, Steven L., Nogales-Gadea, Gisela and Lucia, Alejandro (2016) Rodent models for resolving extremes of exercise and health. Physiological Genomics, 48 2: 82-92. doi:10.1152/physiolgenomics.00077.2015

Grants (Administered at UQ)