The University of Queensland

Pathogenesis of rheumatoid arthritis

Thomas, Ranjeny and Cope, Andrew P. (2013). Pathogenesis of rheumatoid arthritis. In Richard A. Watts, Philip G. Conaghan, Christopher Denton, Helen Foster, John Isaacs and Ulf Müller-Ladner (Ed.), Oxford Textbook of Rheumatology 4th ed. (pp. 839-848) Oxford, United Kingdom: Oxford University Press. doi:10.1093/med/9780199642489.001.0001

Dendritic cells

Lutzky, Viviana and Thomas, Ranjeny (2007). Dendritic cells. In Josef F. Smolen and Peter E. Lipsky (Ed.), Contemporary Targeted therapies in Rheumatology (pp. 63-78) UK: Informa Healthcare.

Identification and isolation of synovial dendritic cells

Pettit, Allison R., Cavanagh, Lois, Boyce, Amanda, Padmanabha, Jagadish, Peng, Judy and Thomas, Ranjeny. (2007). Identification and isolation of synovial dendritic cells. In Andrew P. Cope (Ed.), Arthritis Research Methods and Protocols (pp. 165-181) Totowa, N.J., U.S.A.: Humana Press Inc.

Dendritic Cells

Thomas, Ranjeny, Thompson, Angus G., Martin, Ela and O'Sullivan, Brendan. J. (2003). Dendritic Cells. In Josef S. Smolen and Peter E. Lipsky (Ed.), Targeted Therapies in Rheumatology First ed. (pp. 61-81) London, UK: Martin Duntiz.

Dendritic Cells and Autoimmunity

Thomas, R. (2001). Dendritic Cells and Autoimmunity. In M.T. Lotze and A.W. Thomason (Ed.), Dendritic Cells 2nd ed. (pp. 459-471) United Kingdom: Academic Press.

Identification and isolation of synovial dendritic cells

Pettit, A. R., Cavanagh, L. L. and Thomas, R. (2001). Identification and isolation of synovial dendritic cells. In S. P. Robinson and A. J. Stagg (Ed.), Dendritic Cell Protocols (pp. 175-187) Totowa USA: Humana Press.

Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study

Videm, Vibeke, Thomas, Ranjeny, Brown, Matthew A. and Hoff, Mari (2017) Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study. Journal of Rheumatology, . doi:10.3899/jrheum.161396

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017) Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 10: . doi:10.1126/sciimmunol.aah7152

Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey

Ramos-Remus, Cesar, Barajas-Ochoa, Aldo, Ramirez-Gomez, Andrea, Castillo-Ortiz, Jose D., Brambila-Barba, Victor, Adebajo, Adewale O., Espinoza, Luis R., Aceves-Avila, Francisco J., Sanchez-Gonzalez, Jorge M., Boudersa, Nadia, Slimani, Samy, Ladjouze-Rezig, Aicha, Diaz, Monica P., Kirmayr, Karin I., Asnal, Cecilia A., Catoggio, Luis J., Citera, Gustavo, Casado, Gustavo C., Alvarez, Analia P., Pisoni, Cecilia N., Benavente, Emilio, Lopez-Cabanillas, Adriana, Baez, Roberto M., Pons-Estel, Bernardo A., Sacnun, Monica P., Cavallasca, Javier A., Paniego, Raul H., Proudman, Susanna M., Thomas, Ranjeny, Major, Gabor, Mathers, David M., Schrieber, Leslie, Islam, Nazrul, Haq, Syed A., Dessein, Patrick H., von Muhlen, Carlos A., Bianchi, Washington A., Castelar-Pinheiro, Geraldo da R., Feldman-Pollak, Daniel, Cossermelli, Waldenise, Bonfiglioli, Karina R., Giorgi, Rina D., Zabsonre-Tiendrebeogo, Wendlassida J., Olaru, Lilia, Karsh, Jacob, Castro-Esparza, Irene H., Fuentealba, Carlos, Aguilera, Sergio, Burgos, Paula I., Neira, Oscar, Li, Zhan-guo, Tam, Lai-Shan, Mok, Mo Y., Medina, Yimy F., Zuniga-Vera, Andres E., Moreno-Alvarez, Mario J., Vera, Claudia, Quezada, Ivonne, Moreno, Ivan M., Calapaqui, Wendy, El-Mardenly, Ghada, Salama, M. Salah, Ragab, Gaafar, Gado, Kamel, Hadidi, Tahsin, Leirisalo-Repo, Marjatta, Tuompo, Riitta, Koivuniemi, Riitta, Berenbaum, Francis, Allanore, Yannick, Constantin, Arnaud, Buttgereit, Frank, Schulze-Koops, Hendrik, Liz, Myriam, Dey, Dzifa, Santiago-Pastelin, Carlos B., Alonzo-Borjas, Hugo D., Cuellar-Cruz, Victor, Dharmanand, Balebail G., Yathish, G. C., Akerkar, Shashank M., Malaviya, Anand N., Ahmadzadeh, Arman, Hasunuma, Tomoko, Owino, Benard O., Pacheco-Tena, Cesar, Frausto-Arenas, Aaron, De la Madrid-Cernas, Adrian A., Cardona-Cabrera, Roman, Centeno-Valadez, Juan D., Rodriguez-Torres, Isaura M., Vaidya, Binit, Gupta, Arun K., Harrison, Andrew A., Grainger, Rebecca, Nwankwo, Henry M., Diamantopoulos, Andreas P., Maeland, Elisabeth, Besada, Emilio, Gorriz, Luis, Duarte, Margarita, Cabrera-Villalba, Sonia, Albrecht, Maria T. Romero-de, Garcia-Poma, Augusto, Segami, Maria I., Ramos, Maria P., Perez-Medina, Wilkerson, Dianongco, Maria L., Lichauco, Juan J., Racaza, Geraldine Z., Navarra, Sandra V., Torralba, Tito P., Manapat-Reyes, Bernadette H., Penserga, Ester G., Hammoudeh, Mohammed, Al-Emadi, Samar, Botchkova, Anna G., AlSaeedi, Sabri H., Almoallim, Hani, Al-Arfaj, Hussein F., Koh, Wei H., Leung, Ying Y., Whitelaw, David A., Hodkinson, Bridget, Garcia-Miguel, Javier, Duro, Juan C., Martin-Mola, Emilio, Ahijon-Lana, Maria, Andreu, Jose L., Finckh, Axel, Alpizar-Rodriguez, Deshire, Osiri, Manathip, Kasitanon, Nuntana, Louthrenoo, Worawit, van Vollenhoven, Ronald F., de Vries, Niek, van Denderen, Christiaan, Gerritsen, Martjin, Jansen, Tim L., van Riel, Piet, Nunez-Sotelo, Concepcion M. and Villegas-Morales, Sol (2017) Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology, 36 3: 485-497. doi:10.1007/s10067-016-3481-9

Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features

Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016) Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 OCT: . doi:10.3389/fimmu.2016.00458

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016) Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 5: 1328-1340. doi:10.2337/db15-1418

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

Mutalik, Srinivas, Suthar, Neelam A., Managuli, Renuka S., Shetty, Pallavi K., Avadhani, Kiran, Kalthur, Guruprasad, Kulkarni, Raghavendra V. and Thomas, Ranjeny (2016) Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. International Journal of Biological Macromolecules, 86 709-720. doi:10.1016/j.ijbiomac.2015.11.092

Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice

James, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016) Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 5: 509-519. doi:10.1038/icb.2016.7

Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis

Lau, Max C., Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda A., Hollis, Kelly A., Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2016) Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 34 4: 766-766. doi:10.1136/annrheumdis-2015-208677

Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis

Cummins, L., Katikireddi, V. S., Shankaranarayana, S., Su, K. Y. C., Duggan, E., Videm, V., Pahau, H. and Thomas, R. (2015) Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis. Internal Medicine Journal, 45 12: 1266-1273. doi:10.1111/imj.12896

Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015) Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 8: e41.1-e41.9. doi:10.1038/cti.2015.17

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

Koning, Frits, Thomas, Ranjeny, Rossjohn, Jamie and Toes, Rene E. (2015) Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nature Reviews Rheumatology, 11 8: 450-461. doi:10.1038/nrrheum.2015.59

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Benham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015) Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 290: 290ra87.1-290ra87.11. doi:10.1126/scitranslmed.aaa9301

High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice

Baillet, Athan C., Rehaume, Linda, Benham, Helen, O'Meara, Connor P., Armitage, Charles W., Ruscher, Roland, Brizard, Geraldine, Harvie, Marina C. G., Velasco, Jared, Hansbro, Phillip, Forrester, John V., Degli-Esposti, Mariapia, Beagley, Kenneth W. and Thomas, Ranjeny (2015) High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice. Arthritis and Rheumatology, 67 6: 1535-1547. doi:10.1002/art.39041

IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.

Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh A. K., Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M., Cao, Kim-Anh Le, Isaacs, John D. and Thomas, Ranjeny (2015) IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, 75 2: 466-473. doi:10.1136/annrheumdis-2014-205850

Role of genetics in infection-associated arthritis

Benham, Helen, Robinson, Philip C., Baillet, Athan C., Rehaume, Linda M. and Thomas, Ranjeny (2015) Role of genetics in infection-associated arthritis. Best Practice and Research: Clinical Rheumatology, 29 2: 213-225. doi:10.1016/j.berh.2015.02.002

Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.

Videm, Vibeke, Cortes, Adrian, Thomas, Ranjeny and Brown, Matthew A. (2014) Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.. Journal of Rheumatology, 41 10: 2041-2048. doi:10.3899/jrheum.140353

ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG Mice

Rehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, Daniel, Velasco, Jared, Benham, Helen, Hasnain, Sumaira Zia, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip M., McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2014) ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG Mice. Arthritis and Rheumatology, 66 10: 2780-2792. doi:10.1002/art.38773

Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice

Benham, Helen, Rehaume, Linda M., Hasnain, Sumaira Z., Velasco, Jared, Baillet, Athan C., Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin P., Brown, Matthew A., Strutton, Geoffrey, McGuckin, Michael A. and Thomas, Ranjeny (2014) Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66 7: 1755-1767. doi:10.1002/art.38638

Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT)

Pahau, Helen, Brown, Matthew A., Paul, Sanjoy, Thomas, Ranjeny and Videm, Vibeke (2014) Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT). Arthritis Research and Therapy, 16 2: 1-9. doi:10.1186/ar4527

Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation

McNally, Alice, McNally, Michael, Galea, Ryan, Thomas, Ranjeny and Steptoe, Raymond J. (2014) Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation. PloS One, 9 1: . doi:10.1371/journal.pone.0085455

Dendritic cells as targets or therapeutics in rheumatic autoimmune disease

Thomas, Ranjeny (2014) Dendritic cells as targets or therapeutics in rheumatic autoimmune disease. Current Opinion in Rheumatology, 26 2: 211-218. doi:10.1097/BOR.0000000000000032

Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis

Law, Soi-Chen, Benham, Helen, Reid, Hugh H., Rossjohn, Jamie and Thomas, Ranjeny (2014) Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis. Rheumatic Disease Clinics of North America, 40 4: 735-752. doi:10.1016/j.rdc.2014.07.015

RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface

Thomas, Ranjeny (2013) RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface. Immunology and Cell Biology, 91 9: 543-544. doi:10.1038/icb.2013.51

Th17 and Th22 cells in psoriatic arthritis and psoriasis

Benham, Helen, Norris, Paul, Goodall, Jane, Wechalekar, Mihir D., FitzGerald, Oliver, Szentpetery, Agnes, Smith, Malcolm, Thomas, Ranjeny and Gaston, Hill (2013) Th17 and Th22 cells in psoriatic arthritis and psoriasis. Arthritis Research and Therapy, 15 5: . doi:10.1186/ar4317

Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly

Zeng, B. J., Chuan, Y. P., O’Sullivan, B., Caminschi, I., Lahoud, M. H., Thomas, R. and Middelberg, A. P. J. (2013) Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly. Small, Early View 1-7. doi:10.1002/smll.201300078

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013) Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 6: 1049-1058. doi:10.1182/blood-2012-06-434100

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

Scally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny and Rossjohn, Jamie (2013) A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine, 210 12: 2569-2582. doi:10.1084/jem.20131241

Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis

Thomas, Ranjeny (2013) Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis. Arthritis Research & Therapy, 15 1: 204.1-204.10. doi:10.1186/ar4130

Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges

Thomas, Ranjeny (2013) Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges. Arthritis Research & Therapy, 15 6: . doi:10.1186/ar4420

Targeted delivery of curcumin for treating type 2 diabetes

Maradana, Muralidhara Rao, Thomas, Ranjeny and O'Sullivan, Brendan J. (2013) Targeted delivery of curcumin for treating type 2 diabetes. Molecular Nutrition and Food Research, 57 9: 1550-1556. doi:10.1002/mnfr.201200791

Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort

White, Douglas, Pahau, Helen, Duggan, Emily, Paul, Sanjoy and Thomas, Ranjeny (2013) Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort. BMJ Open, 3 7: e003083.1-e003083.10. doi:10.1136/bmjopen-2013-003083

β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice

Ruutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia A., Zinkernagel, Martin S., Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert J., Kikly, Kristine, Davies, Julian, Pettit, Allison R., Brown, Matthew A., McGuckin, Michael A. and Thomas, Ranjeny (2012) β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice. Arthritis and Rheumatism, 64 7: 2211-2222. doi:10.1002/art.34423

Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis

Kenna, Tony J., Davidson, Stuart I., Duan, Ran, Bradbury, Linda A., McFarlane, Janelle, Smith, Malcolm, Weedon, Helen, Street, Shayna, Thomas, Ranjeny, Thomas, Gethin P. and Brown, Matthew A. (2012) Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis. Arthritis and Rheumatism, 64 5: 1420-1429. doi:10.1002/art.33507

Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes

Irvine, Katharine M., Gallego, Patricia, An, Xiaoyu, Best, Shannon E., Thomas, Gethin, Wells, Christine, Harris, Mark, Cotterill, Andrew and Thomas, Ranjeny (2012) Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes. Diabetes, 61 5: 1281-1290. doi:10.2337/db11-1549

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

Law, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012) T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 3: R118.1-R118.12. doi:10.1186/ar3848

Autoimmunity: innovation in pathogenesis and therapy

Thomas, Ranjeny (2012) Autoimmunity: innovation in pathogenesis and therapy. Immunology and Cell Biology, 90 3: 255-255. doi:10.1038/icb.2012.5

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

Sakaguchi, Shimon, Benham, Helen, Cope, Andrew P. and Thomas, Ranjeny (2012) T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. Immunology and Cell Biology, 90 3: 277-287. doi:10.1038/icb.2012.4

Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion

Chuan, Yap Pang, Zeng, Bi Yun, O'Sullivan, Brendan, Thomas, Ranjeny and Middelberg, Anton P. J. (2012) Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion. Journal of Colloid and Interface Science, 368 1: 616-624. doi:10.1016/j.jcis.2011.11.014

Langerhans cells are precommitted to immune tolerance induction

Shklovskaya, Elena, O'Sullivan, Brendan J., Ng, Lai Guan, Roediger, Ben, Thomas, Ranjeny, Weninger, Wolfgang and de St Groth, Barbara Fazekas (2011) Langerhans cells are precommitted to immune tolerance induction. Proceedings of the National Academy of Sciences of the United States of America, 108 44: 18049-18054. doi:10.1073/pnas.1110076108

Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice

Yekollu, Suman Kumar, Thomas, Ranjeny and O'Sullivan, Brendan (2011) Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice. Diabetes, 60 11: 2928-2938. doi:10.2337/db11-0275

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

O'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011) Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 7: 4018-4030. doi:10.4049/jimmunol.1101727

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011) CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 18: 7529-7534. doi:10.1073/pnas.1103782108

Reduced soluble receptor for advanced glycation end-products in COPD

Smith, D. J., Yerkovich, S. T., Towers, M. A., Carroll, M. L., Thomas, R. and Upham, J. W. (2011) Reduced soluble receptor for advanced glycation end-products in COPD. European Respiratory Journal, 37 3: 516-522. doi:10.1183/09031936.00029310

Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy

Bertin-Maghit, Sebastien, Pang, Dimeng, O'Sullivan, Brendan, Best, Shannon, Duggan, Emily, Paul, Sanjoy, Thomas, Helen, Kay, Thomas W. H., Harrison, Leonard C., Steptoe, Raymond and Thomas, Ranjeny (2011) Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes, 60 1: 248-257. doi:10.2337/db10-0104

Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells

Preston, J. A., Thorburn, A. N., Starkey, M. R., Beckett, E. L., Horvat, J. C., Wade, M. A., O'Sullivan, B. J., Thomas, R., Beagley, K. W., Gibson, P. G., Foster, P. S. and Hansbro, P. M. (2011) Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells. European Respiratory Journal, 37 1: 53-64. doi:10.1183/09031936.00049510

Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease

Thorburn, Alison N., O'Sullivan, Brendan J., Thomas, Ranjeny, Kumar, Rakesh K., Foster, Peter S., Gibson, Peter G. and Hansbro, Philip M. (2010) Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease. Thorax, 65 12: 1053-1060. doi:10.1136/thx.2009.131508

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

Hadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010) IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 8: 723-729. doi:10.1111/j.1600-0625.2010.01092.x

The balancing act of autoimmunity: Central and peripheral tolerance versus infection control

Thomas, Ranjeny (2010) The balancing act of autoimmunity: Central and peripheral tolerance versus infection control. International Reviews of Immunology, 29 2: 211-233. doi:10.3109/08830180903434219

A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

Schroder, Wayne A., Le, Thuy T. T., Major, Lee, Street, Shayna, Gardner, Joy, Lambley, Eleanore, Markey, Kate, MacDonald, Kelli P., Fish, Richard J., Thomas, Ranjeny and Suhrbier, Andreas (2010) A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. Journal of Immunology, 184 5: 2663-2670. doi:10.4049/jimmunol.0902187

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

Kenna, Tony J., Waldie, Tanya, McNally, Alice, Thomson, Meagan, Yagita, Hideo, Thomas, Ranjeny and Steptoe, Raymond J. (2010) Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology, 184 2: 598-606. doi:10.4049/jimmunol.0900032

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

Isomura, I., Palmer, S., Grumont, R. J., Bunting, K., Hoyne, G., Wilkinson, N., Banerjee, A., Proietto, A., Gugasyan, R., Li, W., McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, F. and Gerondakis, S. (2009) c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells. The Journal of Experimental Medicine, 206 13: 3001-3014. doi:10.1084/jem.20091411

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection

Doan, Tracy, McNally, Alice, Thomas, Ranjeny and Steptoe, Raymond (2009) Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection. Immunology and Cell Biology, 87 8: 615-622. doi:10.1038/icb.2009.46

Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis

Hannawi, Suad, Marwick, Thomas and Thomas, Ranjeny (2009) Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis. Arthritis Research and Therapy, 11 2: R51.1-R51.7. doi:10.1186/ar2668

Antigen-specific suppression of inflammatory arthritis using liposomes

Capini, Christelle, Jaturanpinyo, Montree, Chang, Hsin-I, Mutalik, Srinivas, McNally, Alice, Street, Shayna, Steptoe, Raymond, O'Sullivan, Brendan, Davies, Nigel and Thomas, Ranjeny (2009) Antigen-specific suppression of inflammatory arthritis using liposomes. Journal of Immunology, 182 6: 3556-3565. doi:10.4049/jimmunol.0802972

Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis

Chen, Yueh-Sheng, Yan, Weixing, Geczy, Carolyn L., Brown, Matthew A. and Thomas, Ranjeny (2009) Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis. Arthritis Research and Therapy, 11 2: R39 .1-R39 .11. doi:10.1186/ar2645

Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity

Pai, Saparna and Thomas, Ranjeny (2008) Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity. Journal of Autoimmunity, 31 3: 245-251. doi:10.1016/j.jaut.2008.04.012

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

Thomas, Ranjeny, Turner, Malcolm and Cope, Andrew P. (2008) High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?. Arthritis Research and Therapy, 10 4: 1-9. doi:10.1186/ar2446

Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes

Mollah, Zia U.A., Pai, Saparna, Craig Moore, O'Sullivan, Brendan J., Harrison, Matthew J., Peng, Judy, Phillips, Karen, Prins, Johannes B., Cardinal, John and Thomas, Ranjeny (2008) Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes. Journal of Immunology, 180 5: 3166-3175.

Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses

Kenna, Tony J., Thomas, Ranjeny and Steptoe, Raymond J. (2008) Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses. Blood, 111 4: 2091-2100. doi:10.1182/blood-2007-07-103200

Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation

Hannawi, Suad, Haluska, Brian, Marwick, Thomas H. and Thomas, Ranjeny (2007) Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation. Arthritis Research and Therapy, 9 6: R116.1-R116.9. doi:10.1186/ar2323

Cells of the synovium in rheumatoid arthritis: dendritic cells

Lutzky, Viviana, Suad Hannawi, Suad and Thomas, Ranjeny (2007) Cells of the synovium in rheumatoid arthritis: dendritic cells. Arthritis Research and Therapy, 9 4: 219-230. doi:10.1186/ar2200

Plasmodium strain determines dendritic cell function essential for survival from malaria

Wykes, Michelle N., Liu, Xue Q., Beattie, Lynette, Stanisic, Danielle I., Stacey, Katryn J., Smyth, Mark J., Thomas, Ranjeny and Good, Michael F. (2007) Plasmodium strain determines dendritic cell function essential for survival from malaria. PLoS Pathogens, 3 7: e96-0904-e96-0912. doi:10.1371/journal.ppat.0030096

Effector and regulatory T cell function is differentially regulated by RelB within antigen presenting cells during GVHD

MacDonald, Kelli P. A., Kuns, Rachel D., Rowe, Vanessa, Morris, Edward S., Banovic, Tatjana, Bofinger, Helen, O'Sullivan, Brendan, Markey, Kate A., Don, Alistair L., Thomas, Ranjeny and Hill, Geoffrey R. (2007) Effector and regulatory T cell function is differentially regulated by RelB within antigen presenting cells during GVHD. Blood, 109 11: 5049-5057. doi:10.1182/blood-2007-01-067249

Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis

Carroll, Lisa, Frazer, Ian H., Turner, Malcolm, Marwick, Thomas H. and Thomas, Ranjeny (2007) Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis. Arthritis Research and Therapy, 9 2: R39.1-R39.8. doi:10.1186/ar2175

Nasopharyngeal carcinoma-associated Epstein-Barr virus encoded oncogene latent membrane protein 1 potentiates regulatory T cell function

Pai, Saparna, O'Sullivan, Brendan, Abdul-Jabbar, Ibtissam, Peng, Judy, Connoly, Geoff, Khanna, Rajiv and Thomas, Ranjeny (2007) Nasopharyngeal carcinoma-associated Epstein-Barr virus encoded oncogene latent membrane protein 1 potentiates regulatory T cell function. Immunology and Cell Biology, 85 5: 370-377. doi:10.1038/sj.icb.7100046

Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-κB

Martin, E., Capini, C., Duggan, E., Lutzky, V. P., Stumbles, P., Pettit, A. R., O'Sullivan, B. and Thomas, R. (2007) Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-κB. Arthritis And Rheumatism, 56 7: 2255-2266. doi:10.1002/art.22655

NF-kappa B as a therapeutic target in autoimmune disease

O'Sullivan, Brendan J., Thompson, Angus and Thomas, Ranjeny (2007) NF-kappa B as a therapeutic target in autoimmune disease. Expert Opinion On Therapeutic Targets, 11 2: 111-122. doi:10.1517/14728222.11.2.111

Overcoming original antigenic sin to generate new CD8 T cell IFN-gamma responses in an antigen-experienced host

Liu, Xiao Song, Dyer, Joanne, Leggatt, Graham R., Fernando, Germain J. P., Zhong, Jie, Thomas, Ranjeny and Frazer, Ian H. (2006) Overcoming original antigenic sin to generate new CD8 T cell IFN-gamma responses in an antigen-experienced host. Journal of Immunology, 177 5: 2873-2879.

IL-1 beta breaks tolerance through expansion of CD25(+) effector T cells

O'Sullivan, Brendan J., Thomas, Helen E., Pai, Saparna, Santamaria, Pere, Iwakura, Yoichiro, Steptoe, Raymond J., Kay, Thomas W. H. and Thomas, Ranjeny (2006) IL-1 beta breaks tolerance through expansion of CD25(+) effector T cells. Journal of Immunology, 176 12: 7278-7287.

Early combination disease modifying antirheumatic drug treatment for rheumatoid arthritis

Roberts, Lynden J., Cleland, Leslie G., Thomas, Ranjeny and Proudman, Susanna M. (2006) Early combination disease modifying antirheumatic drug treatment for rheumatoid arthritis. Medical Journal of Australia, 184 3: 122-125.

Dendritic cell immunotherapy for melanoma

Peng, J. C., Thomas, R and Dredge, K. (2006) Dendritic cell immunotherapy for melanoma. Reviews on Recent Clinical Trials, 1 2: 87-102. doi:10.2174/157488706776876517

Editorial

Thomas, Ranjeny (2006) Editorial. Wiener medizinische Wochenschrift [electronic resource]., 156 1-2: 1-1. doi:10.1007/s10354-006-0269-6

IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS

Peng, J. C., Abu Bakar, S., Richardson, M. M., Jonsson, J. J., Frazer, I. H., Nielsen, L. K., Morahan, G. and Thomas, R. (2006) IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS. Immunology And Cell Biology, 84 2: 227-232. doi:10.1111/j.1440-1711.2006.01419.x

Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions

Peng, Judy C., Hyde, Claire, Pai, Saparna, O'Sullivan, Brendan J., Nielsen, Lars K. and Thomas, Ranjeny (2006) Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions. Journal of Immunotherapy, 29 6: 606-615. doi:10.1097/01.cji.0000211308.82997.4e

Rheumatoid arthritis: links with cardiovascular disease and the receptor for advanced glycation end products

Carroll, Lisa, Hannawi, Suad, Marwick, Thomas and Thomas, Ranjeny (2006) Rheumatoid arthritis: links with cardiovascular disease and the receptor for advanced glycation end products. Wiener Medizinische Wochenschrift, 156 1-2: 42-52. doi:10.1007/s10354-005-0242-9

Shortcomings of protein removal prior to high performance liquid chromatographic analysis - A case study using method development for BAY 11-7082

Hewavitharana, A. K., Hyde, C., Thomas, R. and Shaw, P. N. (2006) Shortcomings of protein removal prior to high performance liquid chromatographic analysis - A case study using method development for BAY 11-7082. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 834 1-2: 93-97. doi:10.1016/j.jchromb.2006.02.037

Generation and maturation of dendritic cells for clinical application under serum-free conditions

Peng, Judy C., Thomas, Ranjeny and Nielsen, Lars K. (2005) Generation and maturation of dendritic cells for clinical application under serum-free conditions. Journal of Immunotherapy, 28 6: 599-609. doi:10.1097/01.cji.0000175491.21099.04

The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion

MacDonald, Kelli P. A., Rowe, Vanessa, Bofinger, Helen. M., Thomas, Ranjeny, Sasmono, Tedjo, Hume, David A. and Hill, Geoffrey R. (2005) The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion. Journal of Immunology, 175 3: 1399-1405.

The TRAF6-NFκB signaling pathway in autoimmunity: not just inflammation

Thomas, Ranjeny (2005) The TRAF6-NFκB signaling pathway in autoimmunity: not just inflammation. Arthritis Research and Therapy, 7 4: 170-173. doi:10.1186/ar1784

Cytokine expanded myeloid precursors function as regulatory antigen-presenting cells and promote tolerance through IL-10-producing regulatory T cells

MacDonald, Kelli P. A., Rowe, Vanessa, Clouston, Andrew D., Welply, Joseph K., Kuns, Rachel D., Ferrara, James L. M., Thomas, Ranjeny and Hill, Geoffrey R. (2005) Cytokine expanded myeloid precursors function as regulatory antigen-presenting cells and promote tolerance through IL-10-producing regulatory T cells. Journal of Immunology, 174 4: 1841-1850.

Rheumatoid arthritis synovium contains plasmacytoid dendritic cells

Cavanagh, Lois L., Boyce, Amanda, Smith, Louise, Padmanabha, Jagadish, Filgueira, Luis, Pietschmann, Peter and Thomas, Ranjeny (2005) Rheumatoid arthritis synovium contains plasmacytoid dendritic cells. Arthritis Research and Therapy, 7 2: R230-R240. doi:10.1186/ar1467

Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-B-mediated signalling, moderated by TGF-beta

Yan, Mengyong, Peng, Judy, Jabbar, Ibtissam A., Liu, Xiaosong, Filguueira, Luis, Frazer, Ian H. and Thomas, Ranjeny (2005) Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-B-mediated signalling, moderated by TGF-beta. Immunology and Cell Biology, 83 1: 83-91. doi:10.1111/j.1440-1711.2004.01291.x

Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells

Yan, Mengyong, Peng, Judy, Abdul Jabbar, Ibtissam A., Liu, Xiaosong, Filgueira, Luis, Frazer, Ian H. and Thomas, Ranjeny (2004) Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells. Virology, 324 2: 297-310. doi:10.1016/j.virol.2004.03.045

B cell chronic lymphocytic leukaemia cells have reduced capacity to upregulate expression of MHC class I in response to interferon-gamma

Juffs, Helen, Fowler, Nina, Saal, Russell, Grimmett, Karen, Beasley, Shannon, O'Sullivan, Brendan, Frazer, Ian H., Gill, Devinder and Thomas, Ranjeny (2004) B cell chronic lymphocytic leukaemia cells have reduced capacity to upregulate expression of MHC class I in response to interferon-gamma. Pathology, 36 1: 69-76. doi:10.1080/00313020310001644499

Signal 3 and its role in autoimmunity

Thomas, Ranjeny (2004) Signal 3 and its role in autoimmunity. Arthritis Research and Therapy, 6 1: 26-27. doi:10.1186/ar1033

T cells signaled by NF-kappa B- dendritic cells are sensitized not anergic to subsequent activation

Thompson, Angus G., O'Sullivan, Brendan J., Beamish, Heather and Thomas, Ranjeny (2004) T cells signaled by NF-kappa B- dendritic cells are sensitized not anergic to subsequent activation. Journal of Immunology, 173 3: 1671-1680.

Donor pretreatment with progenipoietin-1 is superior to granulocyte colony-stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation

MacDonald, Kelli P. A., Rowe, Vanessa, Filippich, Cheryl, Thomas, Ranjeny, Clouston, Andrew D., Welply, Joseph K., Hart, Derek N. J., Ferrara, James L. M. and Hill, Geoffrey R. (2003) Donor pretreatment with progenipoietin-1 is superior to granulocyte colony-stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation. Blood, 101 5: 2033-2042. doi:10.1182/blood-2002-05-1529

Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10

Martin, Ela, O'Sullivan, Brendan, Low, Pauline and Thomas, Ranjeny (2003) Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity, 18 1: 155-167. doi:10.1016/S1074-7613(02)00503-4

CD40 and dendritic cell function

O'Sullivan, Brendan and Thomas, Ranjeny (2003) CD40 and dendritic cell function. Critical Reviews In Immunology, 23 1-2: 83-107. doi:10.1615/CritRevImmunol.v23.i12.50

Clinical response after intradermal immature dendritic cell vaccination in metastatic melanoma is associated with immune response to particulate antigen

Smithers, Mark, O'Connell, Kathleen, MacFadyen, Susan, Chambers, Melita, Greenwood, Kathryn, Boyce, Amanda, Abdul-Jabbar, Ibtissam, Barker, Kylie, Grimmett, Karen, Walpole, Euan and Thomas, Ranjeny (2003) Clinical response after intradermal immature dendritic cell vaccination in metastatic melanoma is associated with immune response to particulate antigen. Cancer Immunology Immunotherapy, 52 1: 41-52. doi:10.1007/s00262-002-0318-y

Recent advances on the role of CD40 and dendritic cells in immunity and tolerance

O'Sullivan, Brendan and Thomas, Ranjeny (2003) Recent advances on the role of CD40 and dendritic cells in immunity and tolerance. Current Opinion In Hematology, 10 4: 272-278. doi:10.1097/00062752-200307000-00004

Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis

Mould, Arne W., Tonks, Ian D., Cahill, Marian M., Pettit, Allison R., Thomas, Ranjeny, Hayward, Nicholas K. and Kay, Graham F. (2003) Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis. Arthritis and Rheumatism, 48 9: 2660-2669. doi:10.1002/art.11232

Induction of immune tolerance by dendritic cells: implications for preventative and therapeutic immunotherapy of autoimmune disease

Thompson, Angus G. and Thomas, Ranjeny (2002) Induction of immune tolerance by dendritic cells: implications for preventative and therapeutic immunotherapy of autoimmune disease. Immunology and Cell Biology, 80 6: 509-519. doi:10.1046/j.1440-1711.2002.01114.x

Codon modified human papillomavirus type 16 E7 DNA vaccine enhances cytotoxic T-lymphocyte induction and anti-tumour activity

Liu, Wen Jun, Gao, Fengguang, Zhao, Kong Nan, Zhao, Weiming, Fernando, Germain J. G., Thomas, Ranjeny and Frazer, Ian H. (2002) Codon modified human papillomavirus type 16 E7 DNA vaccine enhances cytotoxic T-lymphocyte induction and anti-tumour activity. Virology, 301 1: 43-52. doi:10.1006/viro.2002.1584

CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappa B

O'Sullivan, Brendan J. and Thomas, Ranjeny (2002) CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappa B. The Journal of Immunology, 168 11: 5491-5498.

RelB nuclear translocation mediated by C-terminal activator reigons of Epstein Barr virus-encoded latent membrane protein 1 and its effect on antigen-presenting function in B cells

Pai, Saparna, O'Sullivan, Brendan J., Cooper, Leanne, Thomas, Ranjeny and Khanna, Rajiv (2002) RelB nuclear translocation mediated by C-terminal activator reigons of Epstein Barr virus-encoded latent membrane protein 1 and its effect on antigen-presenting function in B cells. Journal of Virology, 76 4: 1914-1921. doi:10.1128/JVI.76.4.1914-1921.2002

CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappa B

O'Sullivan, Brendan J. and Thomas, Ranjeny (2002) CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappa B. Journal of Immunology, 168 11: 5491-5498.

Nuclear RelB(+) cells are found in normal lymphoid organs and in peripheral tissue in the context of inflammation, but not under normal resting conditions

Thompson, Angus G., Pettit, Allison R., Padmanabha, Jagdish, Mansfield, Helen, Frazer, Ian H ., Strutton, Geoff M. and Thomas, Ranjeny (2002) Nuclear RelB(+) cells are found in normal lymphoid organs and in peripheral tissue in the context of inflammation, but not under normal resting conditions. Immunology and Cell Biology, 80 2: 164-169. doi:10.1046/j.1440-1711.2002.01070.x

Metastatic lesions in the joint associated with acute inflammatory arthritis after dendritic cell immunotherapy for metastatic melanoma

Thomas, R., Padmanabha, J., Chambers, M., McFadyen, S., Walpole, E., Nielssen, G. and Smithers, M. (2001) Metastatic lesions in the joint associated with acute inflammatory arthritis after dendritic cell immunotherapy for metastatic melanoma. Melanoma Research, 11 2: 167-173. doi:10.1097/00008390-200104000-00012

Association of clinical, radiological and synovial immunopathological responses to anti-rheumatic treatment in rheumatoid arthritis

Pettit, AR, Weedon, H, Ahern, M, Zehntner, S, Frazer, IH, Slavotinek, J, Au, V, Smith, MD and Thomas, R (2001) Association of clinical, radiological and synovial immunopathological responses to anti-rheumatic treatment in rheumatoid arthritis. Rheumatology, 40 11: 1243-1255. doi:10.1093/rheumatology/40.11.1243

Comparison of differentiated dendritic cell infiltration of autoimmune and osteoarthritis synovial tissue

Pettit, A. R., Ahern, M. J., Zehntner, S., Smith, M. D. and Thomas, R. (2001) Comparison of differentiated dendritic cell infiltration of autoimmune and osteoarthritis synovial tissue. Arthritis And Rheumatism, 44 1: 105-110. doi:10.1002/1529-0131(200101)44:1<105::AID-ANR14>3.0.CO;2-3

Genomic organization of the CC chemokine MIP-3 alpha/CCL20/LARC/EXODUS/SCYA20, showing gene structure, splice variants, and chromosome localization

Nelson, RT, Boyd, J, Gladue, RP, Paradis, T, Thomas, R, Cunningham, AC, Lira, P, Brissette, WH, Hayes, L, Hames, LM, Neote, KS and McColl, SR (2001) Genomic organization of the CC chemokine MIP-3 alpha/CCL20/LARC/EXODUS/SCYA20, showing gene structure, splice variants, and chromosome localization. Genomics, 73 1: 28-37. doi:10.1006/geno.2001.6482

Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates

Pettit, A. R., MacDonald, K. P., OSullivan, B. J. and Thomas, R. (2000) Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates. Arthritis And Rheumatism, 43 4: 791-800. doi:10.1002/1529-0131(200004)43:4<791::AID-ANR9>3.0.CO;2-E

Immunology of DNA vaccines: CpG motifs and antigen presentation

Manders, P and Thomas, R (2000) Immunology of DNA vaccines: CpG motifs and antigen presentation. Inflammation Research, 49 5: 199-205. doi:10.1007/s000110050580

RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function

O'Sullivan, Brendan J., MacDonald, Kelli P. A., Pettit, Allison R. and Thomas, Ranjeny (2000) RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. Proceedings of the National Academy of Sciences of the United States of America, 97 21: 11421-11426. doi:10.1073/pnas.97.21.11421

Surface markers and transendothelial migration of dendritic cells from elderly subjects

Pietschmann, P, Hahn, P, Kudlacek, S, Thomas, R and Peterlik, M (2000) Surface markers and transendothelial migration of dendritic cells from elderly subjects. Experimental Gerontology, 35 2: 213-224. doi:10.1016/S0531-5565(99)00089-3

Dendric cells: The driving force behind autoimmunity in rheumatoid arthritis

Pettit, Allison R. and Thomas, Ranjeny (1999) Dendric cells: The driving force behind autoimmunity in rheumatoid arthritis. Immunology and Cell Biology, 77 5: 420-427. doi:10.1046/j.1440-1711.1999.00855.x

Dendritic cells and the pathogenesis of rheumatoid arthritis

Thomas, R., MacDonald, K. P. A., Pettit, A. R., Cavanagh, L. L., Padmanabha, J. and Zehntner, S. (1999) Dendritic cells and the pathogenesis of rheumatoid arthritis. Journal of Leukocyte Biology, 66 2: 286-292.

Potential strategies utilised by papillomavirus to evade host immunity

Frazer, Ian H., Thomas, Ranjeny, Zhou, Jian A., Leggatt, Graham R., Dunn, Linda, Mcmillan, Nigel A. J., Tindle, Robert W., Filgueira, Luis, Manders, Peter, Barnard, Paula and Sharkey, Michael (1999) Potential strategies utilised by papillomavirus to evade host immunity. Immunological Reviews, 168 1: 131-142. doi:10.1111/j.1600-065X.1999.tb01288.x

Dendritic cells: the driving force behind autoimmunity in rheumatoid arthritis?

Pettit, Allison R. and Thomas, Ranjeny (1999) Dendritic cells: the driving force behind autoimmunity in rheumatoid arthritis?. Immunology and Cell Biology, 77 5: 420-427. doi:10.1046/j.1440-1711.1999.00855.x

Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy

Thomas, R, Chambers, M, Boytar, R, Barker, K, Cavanagh, LL, MacFadyen, S, Smithers, M, Jenkins, M and Andersen, J (1999) Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy. Melanoma Research, 9 5: 474-481. doi:10.1097/00008390-199910000-00007

Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-101

MacDonald, Kelli P. A., Pettit, Allison R., Quinn, Christopher, Thomas, Gregory J. and Thomas, Ranjeny (1999) Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-101. The Journal of Immunology, 163 10: 5599-5607.

Surfactant treatment for osteoarthritis

Vecchio, P, Thomas, R and Hills, BA (1999) Surfactant treatment for osteoarthritis. Rheumatology, 38 10: 1020-1021. doi:10.1093/rheumatology/38.10.1020

Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy

Zehntner, S, Townsend, W, Parkes, J, Schmidt, C, Down, M, Bell, J, Mulligan, R, ORourke, M, Ellem, K and Thomas, R (1999) Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy. Pathology, 31 2: 116-122.

Antigen-presenting cells in rheumatoid arthritis

Thomas, R (1998) Antigen-presenting cells in rheumatoid arthritis. Springer Seminars In Immunopathology, 20 1-2: 53-72. doi:10.1007/BF00831999

Proliferation in monocyte-derived dendritic cell cultures is caused by progenitor cells capable of myeloid differentiation

Cavanagh, LL, Saal, RJ, Grimmett, KL and Thomas, R (1998) Proliferation in monocyte-derived dendritic cell cultures is caused by progenitor cells capable of myeloid differentiation. Blood, 92 5: 1598-1607.

Functional CD40 ligand is expressed by T cells in rheumatoid arthritis

MacDonald, K. P. A., Nishioka, Y., Lipsky, P. E. and Thomas, R. (1997) Functional CD40 ligand is expressed by T cells in rheumatoid arthritis. Journal of Clinical Investigation, 100 9: 2404-2414. doi:10.1172/JCI119781

Nuclear localization of RelB is associated with effective antigen-presenting cell function

Pettit, Allison R., Quinn, Christopher, MacDonald, Kellie P. A., Cavanagh, Lois L., Thomas, Greg, Townsend, Wendy, Handel, Malcolm and Thomas, Ranjeny (1997) Nuclear localization of RelB is associated with effective antigen-presenting cell function. Journal of Immunology, 159 8: 3681-3691.

Nuclear localization of RelB is associated with effective antigen-presenting cell function

Pettit, A. R., Quinn, C., Cavanagh, L. L., Thomas, G., Townsend, W., Handel, M. and Thomas, R. (1997) Nuclear localization of RelB is associated with effective antigen-presenting cell function. Journal of Immunology, 159 8: 3681-3691.

Peripheral blood chimerism following human liver transplantation

Jonsson, JR, HoganPG, ThomasR, SteadmanC, CloustonAD, BaldersonGA, LynchSV, StrongRW and PowellEE (1997) Peripheral blood chimerism following human liver transplantation. Hepatology, 25 5: 1233-1236. doi:10.1002/hep.510250528

Functional differentiation of dendritic cells in rheumatoid arthritis - Role of CD86 in the synovium

Thomas, R and Quinn, C (1996) Functional differentiation of dendritic cells in rheumatoid arthritis - Role of CD86 in the synovium. Journal of Immunology, 156 8: 3074-3086.

Dendritic cells: Origin and differentiation

Thomas, R and Lipsky, PE (1996) Dendritic cells: Origin and differentiation. Stem Cells, 14 2: 196-206.

Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?

Thomas, R and Lipsky, PE (1996) Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?. Immunology Today, 17 12: 559-564. doi:10.1016/S0167-5699(96)20030-1

Presentation of self peptides by dendritic cells: Possible implications for the pathogenesis of rheumatoid arthritis

Thomas, R and Lipsky, PE (1996) Presentation of self peptides by dendritic cells: Possible implications for the pathogenesis of rheumatoid arthritis. Arthritis and Rheumatism, 39 2: 183-190. doi:10.1002/art.1780390202

CD80 expression in rheumatoid arthritis: Comment

Thomas, R and Lipsky, PE (1995) CD80 expression in rheumatoid arthritis: Comment. Arthritis and Rheumatism, 38 12: 1863-1864. doi:10.1002/art.1780381227

Expression of Cd45Rb and Cd27 Identifies Subsets of Cd4(+) Memory T-Cells with Different Capacities to Induce B-Cell Differentiation

Tortorella, C, Schulzekoops, H, Thomas, R, Splawski, JB, Davis, LS, Picker, LJ and Lipsky, PE (1995) Expression of Cd45Rb and Cd27 Identifies Subsets of Cd4(+) Memory T-Cells with Different Capacities to Induce B-Cell Differentiation. Journal of Immunology, 155 1: 149-162.

Elevated interleukin-10 levels in patients with rheumatoid arthritis

Cush, JJ, Splawski, JB, Thomas, R, McFarlin, JE, Schulzekoops, H, Davis, LS, Fujita, K and Lipsky, PE (1995) Elevated interleukin-10 levels in patients with rheumatoid arthritis. Arthritis and Rheumatism, 38 1: 96-104. doi:10.1002/art.1780380115

Human Peripheral-Blood Dendritic Cell Subsets - Isolation and Characterization of Precursor and Mature Antigen-Presenting Cells

Thomas, R and Lipsky, PE (1994) Human Peripheral-Blood Dendritic Cell Subsets - Isolation and Characterization of Precursor and Mature Antigen-Presenting Cells. Journal of Immunology, 153 9: 4016-4028.

Assessment of a positive selection technique using an avidin column to isolate human peripheral blood T cell subsets

Davis, LS, McIlraith, MJ, Paecheo, T, Becker, B, Adix, LM, Thomas, R, Wacholtz, MC and Lipsky, PE (1994) Assessment of a positive selection technique using an avidin column to isolate human peripheral blood T cell subsets. Journal of Immunological Methods, 175 2: 247-257. doi:10.1016/0022-1759(94)90367-0

Angiocentric T-Cell Lymphoma Masquerading as Cutaneous Vasculitis

Thomas, R, Vuitch, F and Lakhanpal, S (1994) Angiocentric T-Cell Lymphoma Masquerading as Cutaneous Vasculitis. Journal of Rheumatology, 21 4: 760-762.

Rheumatoid Synovial T-Cells Are Functionally Active and Can Contribute to the Pathogenesis of Rheumatoid-Arthritis - Comment On the Article by Matthews Et-Al

Thomas, R, McIlraith, M, Davis, L and Lipsky, P (1994) Rheumatoid Synovial T-Cells Are Functionally Active and Can Contribute to the Pathogenesis of Rheumatoid-Arthritis - Comment On the Article by Matthews Et-Al. Arthritis and Rheumatism, 37 3: 445-446. doi:10.1002/art.1780370326

Rheumatoid Synovium Is Enriched in Mature Antigen-Presenting Dendritic Cells

Thomas, R, Davis, LS and Lipsky, PE (1994) Rheumatoid Synovium Is Enriched in Mature Antigen-Presenting Dendritic Cells. Journal of Immunology, 152 5: 2613-2623.

Incidence, Prevalence and Possible Risk-Factors for Pneumonitis in Patients with Rheumatoid-Arthritis Receiving Methotrexate

Carroll, GJ, Thomas, R, Phatouros, CC, Atchison, MH, Leslie, AL, Cook, NJ and Dsouza, I (1994) Incidence, Prevalence and Possible Risk-Factors for Pneumonitis in Patients with Rheumatoid-Arthritis Receiving Methotrexate. Journal of Rheumatology, 21 1: 51-54.

Comparative Accessory Cell-Function of Human Peripheral-Blood Dendritic Cells and Monocytes

Thomas, R, Davis, LS and Lipsky, PE (1993) Comparative Accessory Cell-Function of Human Peripheral-Blood Dendritic Cells and Monocytes. Journal of Immunology, 151 12: 6840-6852.

Isolation and Characterization of Human Peripheral-Blood Dendritic Cells

Thomas, R, Davis, LS and Lipsky, PE (1993) Isolation and Characterization of Human Peripheral-Blood Dendritic Cells. Journal of Immunology, 150 3: 821-834.

Reduction of leukocyte and interleukin-1β concentrations in the synovial fluid of rheumatoid arthritis patients treated with methotrexate

Thomas, R and Carroll, GJ (1993) Reduction of leukocyte and interleukin-1β concentrations in the synovial fluid of rheumatoid arthritis patients treated with methotrexate. Arthritis and Rheumatism, 36 9: 1244-1252. doi:10.1002/art.1780360909

Rheumatoid Synovium Is Enriched in Cd45Rbdim Mature Memory T-Cells That Are Potent Helpers for B-Cell Differentiation

Thomas, R, McIlraith, M, Davis, LS and Lipsky, PE (1992) Rheumatoid Synovium Is Enriched in Cd45Rbdim Mature Memory T-Cells That Are Potent Helpers for B-Cell Differentiation. Arthritis and Rheumatism, 35 12: 1455-1465. doi:10.1002/art.1780351209

Pyomyositis Complicating the Acquired-Immunodeficiency-Syndrome - a Report of 2 Cases with Coexistent Neutropenia

Thomas, R and French, Mah (1991) Pyomyositis Complicating the Acquired-Immunodeficiency-Syndrome - a Report of 2 Cases with Coexistent Neutropenia. Medical Journal of Australia, 154 7: 481-483.

An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors

Benham, Helen, Wood, John, Nagl, Lisa, Maradana, Muralidhara, Daly, Joshua, Lachner, Nancy, Hugenholtz, Philip and Thomas, Ranjeny (2016). An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors. In: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, (7-7). 30 April–4 May 2016. doi:10.1111/imj.13052

Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research

Benham, Helen, Jensen, Charmaine, Thomas, Ranjeny and Eley, Diann (2016). Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research. In: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, (26-26). 30 April–4 May 2016. doi:10.1111/imj.13052

Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients

Law, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. In: Arthritis & Rheumatology. , , (). .

The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire

van Heemst, Jurgen, Scally, Stephen, Law, Soi Cheng, van der Woude, Diane, Hitchon, Carol, Robinson, David B., Huizinga, T. W. J., Reid, Hugh H., Toes, Rene E. M., El-Gabalawy, Hani, Rossjohn, Jamie and Thomas, Ranjeny (2015). The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire. In: Arthritis & Rheumatology. , , (). .

A Gender Bias in Gut Microbiota of Skg Mice Colonized with a Limited Bacterial Consortium Associated with Severity of Spondyloarthritis and Ileitis Triggered by Beta-Glucan

Rehaume, L., Zbarskaya, O., Kang, A., Bhuyan, Z., Ruscher, R., Benham, H., O Cuiv, P., Morrison, M. and Thomas, R. (2015). A Gender Bias in Gut Microbiota of Skg Mice Colonized with a Limited Bacterial Consortium Associated with Severity of Spondyloarthritis and Ileitis Triggered by Beta-Glucan. In: Internal Medicine Journal. Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, SA, Australia, (38-38). 23–26 May 2015. doi:10.1111/imj.12752

Interleukin-23 Mediates Psoriasis-Like Inflammation in the Skg Mouse Model of Spondyloarthropathy

Benham, H., Rehaume, L., Baillet, A., Bhuyan, Z., Bowman, J., Pang, D., Kikly, K., Strutton, G. and Ranjeny, T. (2015). Interleukin-23 Mediates Psoriasis-Like Inflammation in the Skg Mouse Model of Spondyloarthropathy. In: Special Issue: Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting. 56th Annual Scientific Meeting of the Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, Adelaide, SA Australia, (3-3). 23-26 May 2015. doi:10.1111/imj.12752

Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ

Rehaume, Linda, Kang, Alicia, Zbarskaya, Olga, Mullaney, Jane, Kim, Matthew, Cuiv, Paraic O., Angel, Nicola, Hugenholtz, Philip, Morrison, Mark and Thomas, Ranjeny (2015). Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ. In: *, *, (). *.

Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level

Law, S., Rossjohn, J., Nel, H., La Gruta, N., Reid, H. and Thomas, R. (2015). Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level. In: Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, South Australia, (25-25). 23–26 May 2015. doi:10.1111/imj.12752

Cimt in Individuals with Rheumatoid Arthritis Compared to Individuals with Type 2 Diabetes Mellitus

Pahau, H., Thomas, R., Videm, V., Haluska, B. and Short, L. (2014). Cimt in Individuals with Rheumatoid Arthritis Compared to Individuals with Type 2 Diabetes Mellitus. In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association 55th Annual Scientific Meeting. 55th Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, Hobart, TAS Australia, (30-30). 17-20 May 2014. doi:10.1111/imj.12426

Live attenuated vaccines in rheumatic diseases

Thomas, R. (2014). Live attenuated vaccines in rheumatic diseases. In: 15th Annual European Congress of Rheumatology (EULAR), Paris, France, (50-50). Jun 11-14, 2014. doi:10.1136/annrheumdis-2014-eular.6193

Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.

Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. In: Special Issue: 2014 ACR/ARHP Annual Meeting Abstract Supplemen. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, (S422-S422). 14-19 November 2014. doi:10.1002/art.38914

Phospho-STAT1/3 and Gene Expression Measurement in Circulating CD4(+) T Cells As Diagnostic Tools in Early Autoantibody-Negative Rheumatoid Arthritis.

Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh, Nair, Nisha, Massey, Jonathan, Routledge, Christine, Hargreaves, Ben, Brown, Philip, Barton, Anne, Isaacs, John D. and Thomas, Ranjeny (2014). Phospho-STAT1/3 and Gene Expression Measurement in Circulating CD4(+) T Cells As Diagnostic Tools in Early Autoantibody-Negative Rheumatoid Arthritis.. In: Special Issue: 2014 ACR/ARHP Annual Meeting Abstract Supplemen. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, (S1072-S1073). 14-19 November 2014. doi:10.1002/art.38914

Phospho-STAT1/3 measurement in circulating CD4+T-cells as a diagnostic tool in early autoantibody-negative rheumatoid arthritis

Anderson, A. E., Pratt, A. G., Sedhom, M., Nair, N., Massey, J., Routledge, C., Hargreaves, B., Brown, P., Barton, A., Isaacs, J. D. and Thomas, R. (2014). Phospho-STAT1/3 measurement in circulating CD4+T-cells as a diagnostic tool in early autoantibody-negative rheumatoid arthritis. In: Special Issue: Abstracts of the British Society for Immunology Annual Congress. British Society for Immunology Annual Congress 2014, Brighton, United Kingdom, (182-182). 1-4 December 2014. doi:10.1111/imm.12407

Safety and Retention of Triple Conventional Disease-Modifying Anti-Rheumatic Drug Therapy in Early Rheumatoid Arthritis

Katikireddi, V, Shankaranarayana, S., Cummins, L., Pahau, H., Duggan, E. and Thomas, R. (2014). Safety and Retention of Triple Conventional Disease-Modifying Anti-Rheumatic Drug Therapy in Early Rheumatoid Arthritis. In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association 55th Annual Scientific Meeting. 55th Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, Hobart, TAS Australia, (27-28). 17-20 May 2014. doi:10.1111/imj.12426

Chlamydia Muridarum Induces Reactive Arthritis in Skg Mice: Relationship of Host Immune Control to Inflammatory Disease

Baillet, A., Rehaume, L., Benham, H., O'Meara, C., Armitage, C., Harvie, M., Velasco, J., Beagley, K. and Thomas, R. (2013). Chlamydia Muridarum Induces Reactive Arthritis in Skg Mice: Relationship of Host Immune Control to Inflammatory Disease. In: Annual European Congress of Rheumatology EULAR abstracts. Annual European Congress of Rheumatology - EULAR 2013, Spain, (308-308). 12 - 15 June 2013.

Host Genetic Background Disrupts The Relationship Between Microbiota and Gut Mucosal Tolerance Leading To Spondyloarthritis and Ileitis After a Dectin-1 Trigger.

Rehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, D., Velasco, Jared, Benham, Helen, Hasnain, Sumaira, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip, McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2013). Host Genetic Background Disrupts The Relationship Between Microbiota and Gut Mucosal Tolerance Leading To Spondyloarthritis and Ileitis After a Dectin-1 Trigger.. In: Special Issue: 2013 Annual Meeting Abstract Supplement. 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego Ca, (S1152-S1152). 25-30 October 2013. doi:10.1002/art.38216

Impaired Bacterial Clearance and An Exuberant Inflammatory Response Promote Chlamydia-Induced Reactive Arthritis In SKG Mice

Baillet, Athan, Rehaume, Linda, Benham, Helen, O'Meara, Connor, Armitage, Charles, Harvie, Marina, Brizard, Geraldine, Velasco, Jared, Forrester, John V., Degli-Esposti, Mariapia, Beagley, Kenneth and Thomas, Ranjeny (2013). Impaired Bacterial Clearance and An Exuberant Inflammatory Response Promote Chlamydia-Induced Reactive Arthritis In SKG Mice. In: Abstract Supplement 2013 Annual Meeting. 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego CA, United States, (S1152-S1152). 25-30 October 2013. doi:10.1002/art.38216

Mucosal Associated Invariant T (Mait) Cell Numbers Are Reduced in the Peripheral Blood of Rheumatoid Arthritis Patients

Klinken, Elizabeth, Nel, Hanno and Thomas, Ranjeny (2013). Mucosal Associated Invariant T (Mait) Cell Numbers Are Reduced in the Peripheral Blood of Rheumatoid Arthritis Patients. In: Special Issue: Australasian Society of Clinical Immunology and Allergy (ASCIA) 24th Annual Scientific Meeting. Australasian Society of Clinical Immunology and Allergy (ASCIA) 24th Annual Scientific Meeting, Perth, Western Australia, (10-10). 11-13 September 1013. doi:10.1111/imj.12252

Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes

Thomas, Helen E., Graham, Kate L., Chee, Jonathan, Thomas, Ranjeny, Kay, Thomas W. and Krishnamurthy, Balasubramanian (2013). Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes. In: Narinder K. Mehra, Translational immunology in Asia-Oceania. 5th FIMSA Congress, New Dehli, India, (81-86). 14 -17 March 2012. doi:10.1111/j.1749-6632.2012.06797.x

Antigen-targeting to dendritic cells is required for engraftment of antigen-encoding bone marrow and long-term tolerance under non-myeloablative conditions

Coleman, Miranda, Thomas, Ranjeny and Steptoe, Ray (2012). Antigen-targeting to dendritic cells is required for engraftment of antigen-encoding bone marrow and long-term tolerance under non-myeloablative conditions. In: Immunology 2012 Meeting Abstracts. 99th Annual Meeting of the American Association of Immunologists, Boston, MA, United States, (). 4 -8 May 2012.

Cardiovascular risk factors and events are more frequent prior to the onset of rheumatoid arthritis than in the general population

Pahau, Helen, Videm, Vibeke, Paul, Sanjoy and Thomas, Ranjeny (2012). Cardiovascular risk factors and events are more frequent prior to the onset of rheumatoid arthritis than in the general population. In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting. Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, DC, United States, (S512-S513). 9-14 November 2012. doi:10.1002/art.37735

Early rheumatoid arthritis management and potential vaccine-based therapeutics

Thomas, R. (2012). Early rheumatoid arthritis management and potential vaccine-based therapeutics. In: Abstracts for the RACP Future Directions in Health Congress 2012. RACP Future Directions in Health Congress 2012, Brisbane, QLD, Australia, (12-12). 6-9 May 2012. doi:10.1111/j.1445-5994.2012.02779.x

Incidence and severity of spondyloarthritis and Crohn's Ileitis are determined by interaction between the microbiota and genetic susceptibility in beta-glucan-treated SKG mice

Thomas, Ranjeny, Rehaume, Linda, Aguirre de Cárcer, Daniel, Mondot, Stan, Velasco, Jared, Benham, Helen, Ruutu, Merja, Morrison, Mark and McGuckin, Michael (2012). Incidence and severity of spondyloarthritis and Crohn's Ileitis are determined by interaction between the microbiota and genetic susceptibility in beta-glucan-treated SKG mice. In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting. Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, DC, United States, (S1053-S1053). 9-14 November 2012. doi:10.1002/art.37735

Outcome of a phase I trial of rheumavax in patients with rheumatoid arthritis

Nel, H., Law, S., Street, S., Ramnoruth, N., Shams, R., Pahau, H., Brunck, M., Hyde, C., O'Sullivan, B., Capini, C., Tran, A., Ng, J., Godfrey, D. and Thomas, R. (2012). Outcome of a phase I trial of rheumavax in patients with rheumatoid arthritis. In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting. 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals, Canberra ACT, Australia, (10-10). 12-15 May 2012. doi:10.1111/j.1445-5994.2012.02761.x

Protective and Pathogenic Effects of the Il-23 Family of Cytokines in Spondyloarthropathy in Skg Mice

Benham, H., Rehaume, L., Ruutu, M., Velasco, J., Strutton, G., McGuckin, M. and Thomas, R. (2012). Protective and Pathogenic Effects of the Il-23 Family of Cytokines in Spondyloarthropathy in Skg Mice. In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting. 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals, Canberra ACT, Australia, (5-5). 12-15 May 2012. doi:10.1111/j.1445-5994.2012.02759.x

Protective and pathogenic effects of the IL-23 family of cytokines in spondyloarthropathy in SKG mice

Benham, Helen, Rehaume, Linda, Ruutu, Merja, Velasco, Jared, Kikly, Kristine, Strutton, Geoffrey, McGuckin, Michael and Thomas, Ranjeny (2012). Protective and pathogenic effects of the IL-23 family of cytokines in spondyloarthropathy in SKG mice. In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting. Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, DC, United States, (S1052-S1052). 9-14 November 2012. doi:10.1002/art.37735

PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTS

Street, S., Purcell, A., Law, S., Yu, A., Capini, C., O'Sullivan, B., Pahau, H. and Thomas, R. (2011). PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTS. In: Internal Medicine Journal. , , (14-14). .

Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritis

Thomas, Ranjeny, Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Law, Soi, Brunck, Marion, Hyde, Claire, O'Sullivan, Brendan, Capini, C., Tran, A., Ng, J. and Paul, S. (2011). Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritis. In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting. 75th Annual Scientific Meeting of the American College of Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, Chicago, IL, United States, (S946-S946). 04-09 November 2011. doi:10.1002/art.33310

The Role of Gut Microflora and Autoreactive CD4+T Cells in the Development of Spondyloarthritis and Inflammatory Bowel Disease in Beta-Glucan-Treated SKG Mice

Ruutu, Merja, Velasco, Jared, Aguirre, Daniel, Benham, Helen, Morrison, Mark, McGuckin, Michael and Thomas, Ranjeny (2011). The Role of Gut Microflora and Autoreactive CD4+T Cells in the Development of Spondyloarthritis and Inflammatory Bowel Disease in Beta-Glucan-Treated SKG Mice. In: Abstracts of the American College of Rheumatology and Association of Rheumatology Health Professionals Annual Scientific Meeting. 75th Annual Scientific Meeting of the American College of Rheumatology/46th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, Chicago, IL, United States, (S668-S668). 4-9 November 2011. doi:10.1002/art.33310

Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity

O'Sullivan, B, Pai, S, Street, S, MacDonald, K, Gerondakis, S, Hill, G and Thomas, R (2010). Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity. In: Abstract Supplement - 10th Annual Meeting, Federation of Clinical Immunology Societies. 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, Boston, MA, U.S.A., (S-134-S-135). 24-27 June 2010. doi:10.1016/j.clim.2010.03.407

F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes

Pai, S, Best, S, Roddick, J, Pahao, H, Baskerville, T, Brown, M, Harris, M, Cotterill, A and Thomas, R (2010). F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes. In: FOCIS 2010 Abstract Supplement :10th Annual Meeting, Federation of Clinical Immunology Societies. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., (S82-S82). 24-27 June 2010. doi:10.1016/j.clim.2010.03.247

F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy

Bertin-Maghit, Sebastien, O'Sullivan, Brendan, Best, Shannoiin, Duggan, Emily, Pang, Dimeng, Thomas, Helen, Kay, Thomas, Harrison, Leonard, Steptoe, Raymond and Thomas, Ranjeny (2010). F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. In: FOCIS 2010 Abstract Supplement :10th Annual Meeting, Federation of Clinical Immunology Societies. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., (S98-S98). 24-27 June 2010. doi:10.1016/j.clim.2010.03.294

RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes

Pai, S., Best, S. E., Mollah, Z. U., Prins, J., Brown, M. and Thomas, R. (2008). RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes. In: Immunology. Annual Congress of the British-Society-of-Immunology, Glasgow Scotland, (42-42). Nov 17-21, 2008.

Assessment of liposomes for delivery of selected NFkB inhibitors

Jaturanpinyo, M., Thomas, R. and Davies, N. M. (2006). Assessment of liposomes for delivery of selected NFkB inhibitors. In: Transactions of the 33rd Annual Meeting and Exposition of the Controlled Release Society. 33rd Annual Meeting of the Controlled Release Society: The art of science, technology, and living, Vienna Austria / Austria Center, (1-2). 22-26 July 2006.

Peripheral blood T cell reactivity to citrullinated autoantigenic peptides in Anti-CCP plus rheumatoid arthritis patients

Capini, C., Hyde, C., O'Sullivan, B. and Thomas, R. (2006). Peripheral blood T cell reactivity to citrullinated autoantigenic peptides in Anti-CCP plus rheumatoid arthritis patients. In: Arthritis And Rheumatism. The 70th Annual Scientific Meeting of the American College of Rheumatology and 41st Annual Scientific Meeting of the Association of Rheumatology Health Professionals, Washington, DC, U.S.A., (S509-S510). 10-15 November, 2006.

B, NK and NKT cells contribute to suppression of immunity by dendritic cells

Lutzky, V. P. and Thomas, R. (2005). B, NK and NKT cells contribute to suppression of immunity by dendritic cells. In: Tissue Antigens: 'Genetics and The Immune Response'Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop. The 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop, Melbourne, Australia, (484-485). 29th November - 2nd December, 2005. doi:10.1111/j.1399-0039.2005.00523.x

Defective NF-kappaB Activation in Response to LPS in Type 1 Diabetes Dendritic Cells

Mollah, Z. U. A., Moore, C., Sullivan, B., Peng, J., Phillips, K., Cardinal, J., Prins, J. and Thomas, R. (2005). Defective NF-kappaB Activation in Response to LPS in Type 1 Diabetes Dendritic Cells. In: Munksgaard, Tissue Antigens: 'Genetics and The Immune Response', Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop. The 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop, Melbourne, Australia, (496-496). 29th November - 2nd December, 2005. doi:10.1111/j.1399-0039.2005.00523.x

Effect of drug-protein interactions on drug assay

Hewavitharana, A., Shaw, N., Hyde, C. and Thomas, R. (2005). Effect of drug-protein interactions on drug assay. In: E. A. Davis and C. G. Sobey, Program & Abstracts: Joint Meeting of ASCEPT and APSA 2005. Joint Meeting of ASCEPT and APSA, Melbourne, Australia, (2-39). 4-7 December 2005.

Feasibility of left main coronary artery imaging in the clinical laboratory

Jenkins, Carly, Hannawi, Suad, Jeffriess, Leanne, Thomas, Ranjeny and Marwick, Thomas (2005). Feasibility of left main coronary artery imaging in the clinical laboratory. In: Heart Lung and Circulation: Abstracts for the Cardiac Society of Australia and New Zealand and International Society for Heart Research Annual Scientific Meeting. Cardiac Society of Australia and New Zealand Annual Scientific Meeting, Perth, W. A ., (S29-S29). 5-8 August 2005. doi:10.1016/j.hlc.2005.04.007

IL-1 breaks tolerance through inhibition of regulatory T cell function

O'Sullivan, B. J., Thomas, H. E., Pai, S., Steptoe, R. J., Kay, T. W. and Thomas, R. (2005). IL-1 breaks tolerance through inhibition of regulatory T cell function. In: Tissue Antigens: 'Genetics and The Immune Response' Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop. 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop, Melbourne, Australia, (505-505). 29th November - 2nd December, 2005. doi:10.1111/j.1399-0039.2005.00523.x

Il-1 beta breaks tolerance through inhibition of regulatory T cell function

O'Sullivan, B., Thomas, H., Jamieson, E., Pai, S., Steptoe, R., Kay, T. and Thomas, R. (2005). Il-1 beta breaks tolerance through inhibition of regulatory T cell function. In: Arthritis and Rheumatism. 69th Annual Scientific Meeting of the American-College-of-Rheumatology/40th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, San Diego, CA, (S487-S487). 12th - 17th December, 2005.

Inhibition of NF kappa B leads to an intracellular reducing environment in human monocyte-derived immature dendritic cells

Dredge, K., O'Sullivan, B., Cameron, S., Walshe, J., Saunders, N., Hultqvist, M., Holmdahl, R. and Thomas, R. (2005). Inhibition of NF kappa B leads to an intracellular reducing environment in human monocyte-derived immature dendritic cells. In: Tissue Antigens: 'Genetics and The Immune Response' 35th Annual Scientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops. The 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop, Melbourne, Australia, (400-401). 29th November - 2nd December, 2005. doi:10.1111/j.1399-0039.2005.00523.x

Liposomal encapsulation of the NF-kB inhibitor, Bay 11-7082

Jaturanpinyo, M., Davies, N. M. and Thomas, R. (2005). Liposomal encapsulation of the NF-kB inhibitor, Bay 11-7082. In: E. A. Davis and C. G. Sobey, Program & Abstracts: Joint Meeting of ASCEPT and APSA 2005. Joint Meeting of ASCEPT and APSA, Melbourne, (2-56). 4-7 December 2005.

Nuclear translocation of ROB within host and donor antigen presenting cells is critical for the initiation and maintenance of acute graft-versus-host disease

MacDonald, Kelli, Kuns, Rachel, Rowe, Vanessa, Don, Alistair, Morris, Edward, Thomas, Ranjeny and Hill, Geoffrey (2005). Nuclear translocation of ROB within host and donor antigen presenting cells is critical for the initiation and maintenance of acute graft-versus-host disease. In: Abstracts of the 47th Annual Meeting of the American Society of Hematology. 47th Annual Meeting of the American Society of Hematology, Atlanta, GA, United States, (137A-137A). 10 -13 December 2005.

Targeting Antigen-loaded Liposomes to Myeloid Antigen Presenting Cells

Capini, C., Jaturanpinyo, M., Gautam, A., Davies, N. and Thomas, R. (2005). Targeting Antigen-loaded Liposomes to Myeloid Antigen Presenting Cells. In: Tissue Antigens: 'Genetics and The Immune Response' Abstracts of the 35th Annual Scientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops. 35th Annual Scentific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, Australia, (372-373). 29th November - 2nd December, 2005. doi:10.1111/j.1399-0039.2005.00523.x

The mechanism of inflammation in RelB deficient mice

Pai, S., O'Sullivan, B. J., MacDonald, K. P., Duggan, E., Gerondakis, S., Hill, G. and Thomas, R. (2005). The mechanism of inflammation in RelB deficient mice. In: Tissue Antigens: 'Genetics and The Immune Response' Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop. 35th Annual Scentific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, Australia, (507-507). 29 November - 2 December 2005.

Cytokine expanded myeloid precursors function as regulatory antigen presenting cells and induce tolerance through IL-10 producing regulatory T cells

MacDonald, K. P. A., Rowe, V., Thomas, R., Ferrera, J. L. M. and Hill, G. R. (2004). Cytokine expanded myeloid precursors function as regulatory antigen presenting cells and induce tolerance through IL-10 producing regulatory T cells. In: Immunology and Cell Biology. 22nd Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand, Canberra, Australia, (A15-A15). 31st March - 2nd April, 2004. doi:10.1111/j.1440-1711.2004.1259_2.x

Antigen-specific suppression of inflammatory arthritis by dendritic cells

Thomas, R., Martin, E. and O'Sullivan, B. J. (2003). Antigen-specific suppression of inflammatory arthritis by dendritic cells. In: Arthritis Research and Therapy. 3rd World Congress of the Global-Arthritis-Research-Network (GARN), Miyakazi, Japan, (S34-S34). 14th - 17th September, 2003. doi:10.1186/ar908

Antigen-specific suppression of inflammatory arthritis by dendritic cells

Martin, E., O'Sullivan, B. J. and Thomas, R. (2003). Antigen-specific suppression of inflammatory arthritis by dendritic cells. In: Arthritis and Rheumatism. 67th Annual Scientific Meeting of the American College of-Rheumatology/38th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, Orlando, Florida, U.S.A., (S150-S151). 23 - 28 October 2003.

Progenipoietin-1 and G-CSF expand a novel CD40(neg) APC that induces transplant tolerance through IL-10 producing regulatory T cells

MacDonald, K. P. A., Rowe, V., Thomas, R., Welply, J. K., Woulfe, S., Ferrara, J. L. M. and Hill, G. R. (2003). Progenipoietin-1 and G-CSF expand a novel CD40(neg) APC that induces transplant tolerance through IL-10 producing regulatory T cells. In: Abstracts of the 45th Annual Meeting of the American Society of Hematology. 45th Annual Meeting of the American Society of Hematology, San Diego, CA, United States, (191A-191A). 6 - 9 December 2003.

Transduction of B-CLL cells with recombinant lentiviral human CD40 ligand and its effects on antigen presenting cell function

Juffs, H. G., Boyce, A., Gill, D. and Thomas, R. (2001). Transduction of B-CLL cells with recombinant lentiviral human CD40 ligand and its effects on antigen presenting cell function. In: Abstracts of the 43rd Annual Meeting of the American Society of Hematology. 43rd Annual Meeting of the American Society of Hematology, Orlando, FL, United States, (152A-152A). 7-11 December 2001.

Rheumatoid arthritis clinical activity and radiological progression are related to synovial dendritic cell, lymphocyte and macrophage infiltration and TNF alpha expression

Pettit, A. R., Weedon, H., Ahern, M., Zehntner, S., Slavotinek, J., Au, V., Smith, M. D. and Thomas, R. (2000). Rheumatoid arthritis clinical activity and radiological progression are related to synovial dendritic cell, lymphocyte and macrophage infiltration and TNF alpha expression. In: American College of Rheumatology Annual Scientific Meeting, Philadelphia, PA, USA, (S156-S156). 28 October - 2 November 2000.

Dendritic cells in rheumatoid arthritis - A model autoimmune inflammatory site

Thomas, R. (1998). Dendritic cells in rheumatoid arthritis - A model autoimmune inflammatory site. In: -, -, (15-15). -.

Proliferation in monocyte-derived dendritic cell cultures is due to cells capable of myeloid differentiation

Cavanagh, L. L., Saal, R. J., Grimmett, K. L. and Thomas, R. (1998). Proliferation in monocyte-derived dendritic cell cultures is due to cells capable of myeloid differentiation. In: -, -, (21-21). -.

Functional CD40-ligand is expressed by T cells in rheumatoid arthritis

MacDonald, K., Nishioka, Y., Lipsky, P. and Thomas, R. (1997). Functional CD40-ligand is expressed by T cells in rheumatoid arthritis. In: The journal of allergy and clinical immunology. AAAAI/AAI/CIS Joint Meeting, -, (s182-s182). 21st - 26th February, 1997. doi:10.1016/S0091-6749(97)81064-0

Nuclear localisation of relB is associated with potent antigen presenting cell function

Thomas, R., Pettit, A., Quinn, Christopher, MacDonald, K. and Cavanagh, L. (1997). Nuclear localisation of relB is associated with potent antigen presenting cell function. In: AAAAI/AAI/CIS Joint Meeting, -, (s450-s450). 21st – 26th February, 1997. doi:10.1016/S0091-6749(97)81067-6

Rheumatoid arthritis synovial tissue and not synovial fluid, DC express high levels of active nuclear RelB

Pettit, A. R., Quinn, C., Cavanagh, L. L., Thomas, G., Townsend, W., Handel, M. and Thomas, R. (1997). Rheumatoid arthritis synovial tissue and not synovial fluid, DC express high levels of active nuclear RelB. In: -, -, (610-610). -.

Rheumatoid synovial fluid dendritic cells are resistant to the inhibitory effects of IL-10

Thomas, R., Macdonald, K., Moore, K., Pettit, A., Quinn, C., Thomas, G. and OSullivan, B. (1997). Rheumatoid synovial fluid dendritic cells are resistant to the inhibitory effects of IL-10. In: Arthritis and Rheumatism. 61st National Scientific Meeting of the American College of Rheumatology and the 32nd National Scientific Meeting of the Association of Rheumatology Health Professionals, Washington D.C., U.S., (536-536). 8-12 November 1997.

Transendothelial migration of human dendritic cells

Cavanagh, L. L., Pietschmann, P., Stohlawetz, P., Klosner, G. and Thomas, R. (1997). Transendothelial migration of human dendritic cells. In: Arthritis and Rheumatism. -, -, (276-276). 1997.

Immunomodulating compositions, processes for their production and uses therefore

O'Sullivan, Brendan J. and Ranjeny, Thomas (2003). Immunomodulating compositions, processes for their production and uses therefore. 2003249780; PCT/AU2003/001021; WO2004/015056.