Dr Katharine Irvine

Senior Research Fellow

Mater Research Institute-UQ
Faculty of Medicine
katharine.irvine@uq.edu.au
+61 7 344 38014

Overview

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Laws, University of New South Wales
  • Bachelor of Science (Hons), University of New South Wales

Publications

  • Patel, Preya, Cheng, Johnson Chieh-Yu, Banh, Xuan, Hossain, Fabrina, Horsfall, Leigh Ula, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine A., Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine, Clouston, Andrew D., Bernard, Anne and Powell, Elizabeth E. (2018). Advanced Fibrosis Is Associated with Longitudinal Increases in Fibrosis-4 and NAFLD Fibrosis Scores. In: Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco Ca, (1291A-1291A). Nov 09-13, 2018.

  • Irvine, Katharine, Genz, Berit, Clouston, Andrew D. and Hume, David (2018). Macrophage Colony Stimulating Factor (CSF1) Promotes Regression of Advanced Fibrosis and Liver Regeneration in Mice. In: Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco Ca, (635A-635A). Nov 09-13, 2018.

  • Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Bernard, Anne, Brown, Nigel Neil, Lampe, Guy, Buck, Lyndall, Saad, Nivene, Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Rosenberg, William and Powell, Elizabeth Ellen (2018) A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care. Hepatology Communications, 2 8: 893-905. doi:10.1002/hep4.1208

View all Publications

Supervision

  • Master Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

Journal Article

Conference Publication

  • Patel, Preya, Cheng, Johnson Chieh-Yu, Banh, Xuan, Hossain, Fabrina, Horsfall, Leigh Ula, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine A., Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine, Clouston, Andrew D., Bernard, Anne and Powell, Elizabeth E. (2018). Advanced Fibrosis Is Associated with Longitudinal Increases in Fibrosis-4 and NAFLD Fibrosis Scores. In: Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco Ca, (1291A-1291A). Nov 09-13, 2018.

  • Irvine, Katharine, Genz, Berit, Clouston, Andrew D. and Hume, David (2018). Macrophage Colony Stimulating Factor (CSF1) Promotes Regression of Advanced Fibrosis and Liver Regeneration in Mice. In: Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco Ca, (635A-635A). Nov 09-13, 2018.

  • Patel, P. J., Smith, D. D., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N. N., Saad, N., Clouston, A. D., Irvine, K. M., Russell, A. W., Valery, P. C. and Powell, E. E. (2017). Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?. In: Journal of Hepatology. International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Amsterdam Netherlands, (S588-S588). Apr 19-23, 2017. doi:10.1016/S0168-8278(17)31602-1

  • Patel, P. J., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Saad, N., Clouston, A., Irvine, K. M., Russell, A., Valery, P. C. and Powell, E. E. (2017). Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes. In: , , (103-103). .

  • Hayward, K. L., Patel, P. J., Valery, P. C., Horsfall, L. U., Li, C. Y., Wright, P. L., Tallis, C. J., Stuart, K. A., Irvine, K. M., Cottrell, W. N., Powell, E. E. and Martin, J. H. (2017). High-risk medication-related problems are prevalent in people with decompensated cirrhosis. In: Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD, Australia, (95-95). 20 - 22 August 2017.

  • Hayward, K. L., Valery, P. C., Martin, J. H., Karmakar, A., Patel, P. J., Horsfall, L. U., Irvine, K. M., Stuart, K. A., Tallis, C. J., Wright, P. L., Smith, D. D., Powell, E. E. and Cottrell, W. N. (2017). Medication beliefs predict low medication adherence in people with decompensated cirrhosis. In: International Liver Congress / 52nd Annual Meeting of the European Association for the Study of the Liver. International Liver Congress / 52nd Annual Meeting of the European Association for the Study of the Liver, Amsterdam, The Netherlands, (S382-S383). 19 - 23 April 2017. doi:10.1016/S0168-8278(17)31113-3

  • Hayward, K. L., Cottrell, W. N., Karmakar, A., Patel, P. J., Horsfall, L. U., Martin, J. H., Irvine, K. M., Tallis, C. J., Wright, P. L., Stuart, K. A., Valery, P. C. and Powell, E. E. (2016). Medication adherence in outpatients with decompensated cirrhosis. In: Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, (103-103). 10–12 October, 2016. doi:10.1111/jgh.13520

  • Patel, P. J., Stuart, K. A., Horsfall, L. U., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Clouston, A., Irvine, K. M., Russell, A. and Powell, E. E. (2016). Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes. In: Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, (114-115). 10–12 October, 2016. doi:10.1111/jgh.13520

  • Irvine, K. M., Clouston, A. D., Blumenthal, A. and Powell, E. E. (2015). Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation. In: Abstracts of Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD, Australia, (7-7). 28 September - 2 October 2015. doi:10.1111/jgh.13087

  • Irvine, Katharine, Clouston, Andrew D., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury. In: 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, United States, (878A-878A). Nov 13-17, 2015.

  • Hayward, K., Valery, P. C., Cottrell, N., Irvine, K., Horsfall, L., Ruffin, B., Tallis, C., Chachay, V., Martin, J. and Powell, E. (2015). Discrepancies in the use of medications in patients with cirrhosis. In: Abstracts of Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD, Australi, (101-102). 28 September - 2 October 2015. doi:10.1111/jgh.13093

  • Mcphail, S. M., Horsfall, L., Irvine, K., Fagan, K. J. and Powell, E. E. (2015). Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal. In: Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 World Congress of Gastroenterology, Brisbane, Queensland, Australia, (108-109). 28 September-2 October 2015. doi:10.1111/jgh.13093

  • El-Atem, N., Wojcik, K., Horsfall, L., Irvine, K., Johnson, T., Mcphail, S. M. and Powell, E. E. (2015). Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease. In: Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, Queensland, Australia, (100-101). 28 September-2 October 2015. doi:10.1111/jgh.13093

  • Irvine, Katharine, Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin, Horsfall, Leigh, Fletcher, Linda, Ungerer, Jacobus, Pretorius, Carel J., Miller, Gregory, Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. In: 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, (600A-600A). 13-17 November 2015. doi:10.1002/hep.28218

  • Irvine, K. M., Wockner, L. F., Shanker, M., Fagan, K. J., Horsfall, L. U., Fletcher, L. M., Ungerer, J., Pretorius, C. J., Miller, G. C., Clouston, A. D., Lampe, G. and Powell, E. E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. In: Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, Queensland, Australia, (104-105). 28 September-2 October 2015. doi:10.1111/jgh.13093

  • Fagan, K., Horsfall, L., Irvine, K., Fletcher, L., Tate, J., Choi, K., Nusrat, S., Melino, M., Clouston, A., Ballard, E., O'Rourke, P., Lampe, G., Ungerer, J. and Powell, E. (2014). An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease. In: Journal of Gastroenterology and Hepatology. , , (77-78). .

  • Fagan, K. J., Melino, M., Powell, E. E. and Irvine, K. M. (2014). Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites. In: Special Issue: Australian Gastroenterology Week 2014. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, (81-81). 22-24 October 2014. doi:10.1111/jgh.12736_5

  • Melino, M., Gadd, V., Martinez, M., Lineburg, K., Irvine, K., Clouston, A. D., Powell, E. E. and Macdonald, K. P. (2014). Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model. In: Special Issue: Australian Gastroenterology Week 2014. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, (8-9). 22-24 October 2014. doi:10.1111/jgh.12736

  • Gadd, Victoria L., Skoien, Richard, Fagan, Kevin, Irvine, Katharine, Powell, Elizabeth E. and Clouston, Andrew D. (2013). The Portal Inflammatory Infiltrate and Ductular Niche in Non-Alcoholic Fatty Liver Disease. In: 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases, Washington Dc, (458A-458A). Nov 01-05, 2013.

  • Fagan, K., Irvine, K., Kumar, S., Bates, A., Horsfall, L., Feeney, G. and Powell, E. (2013). Assessment of alcohol histories obtained from patients with liver disease: Opportunities to improve early intervention. In: Australian Gastroenterology Week 2013, Melbourne, Australia, (61-61). 7-9 October 2013. doi:10.1111/jgh.12365_5

  • Fagan, K., Irvine, K., McWhinney, B., Fletcher, L., Horsfall, L., Johnson, L., Clouston, A., Jonsson, J., O'Rourke, P., Martin, J., Pretorius, C., Ungerer, J. and Powell, E. (2013). BMI but not aetiology or stage of liver disease affects the diagnostic sensitivity of carbohydrate deficient transferrin. In: International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Amsterdam Netherlands, (S215-S215). 24-28 April 2013. doi:10.1016/S0168-8278(13)60527-9

  • Zhao, E., Horsfall, L., Ruffin, B. J., Fagan, K. J., Irvine, K. M. and Powell, E. E. (2013). Factors associated with mortality and unplanned hospital readmissions in patients with ascites. In: Australian Gastroenterology Week 2013, Melbourne, Australia, (79-80). 7-9 October 2013. doi:10.1111/jgh.12365_5

  • Gadd, V., Skoien, R., Fagan, K., Irvine, K., Powell, E. and Clouston, A. (2013). The portal inflammatory infiltrate and ductular niche in non-alcoholic fatty liver disease. In: Australian Gastroenterology Week 2013, Melbourne Australia, (9-10). 7-9 October 2013. doi:10.1111/jgh.12365

  • Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. In: Abstracts of the European Congress of Immunology. European Congress of Immunology, Glasgow, Scotland, (297-297). 5-8 September 2012. doi:10.1111/imm.12002

  • Irvine, Katharine M., Andrews, Melanie R., Fernandez, Manuel A., Parton, Robert G., Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Hume, David A. and Sweet, M. J. (2008). The identification of novel CSF-1 target genes in human macrophages. In: Cytokine. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, Montreal Canada, (245-245). Oct 12-16, 2008. doi:10.1016/j.cyto.2008.07.078

  • Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Bu, Xiangyong, Harte, Michael F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2005). A potent CSF-1 Receptor tyrosine kinase inhibitor targets survival and effector functions in marine macrophage populations. In: Inflammation Research. , , (S148-S148). .

  • Schroder, Kate, Irvine, Katharine M., Biron, Kristian, Lichtinger, Monika, Ravasi, Timothy, Rehli, Michael, Sweet, Matthen J. and Hume, David A. (2005). PU.1 and ICSBP regulate the tlr9 promoter in mouse macrophages. In: Inflammation Research. , , (S186-S187). .

Other Outputs

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors: