The University of Queensland

Immunoprecipitation and Phosphorylation of G Protein-Coupled Receptors

Thomas, Walter (2009). Immunoprecipitation and Phosphorylation of G Protein-Coupled Receptors. G Protein-Coupled Receptors in Drug Discovery. (pp. 359-371) edited by Wayne R. Leifert. USA: Springer Science & Business Media, LLC. doi: 10.1007/978-1-60327-317-6_26

ADAMs as mediators of AngII actions

Bourne, A.M. and Thomas, W.G. (2007). ADAMs as mediators of AngII actions. Frontiers in Research of the Renin-Angiotensin System on Human Disease. (pp. 273-302) edited by Po Sing Leung. Dordrecht, The Netherlands: Springer, Heidelberg.

ADAMs as mediators of Angiotensin II actions.

Bourne, A. M. and Thomas, W. G. (2007). ADAMs as mediators of Angiotensin II actions.. Frontiers in Research of the Renin-Angiotensin System on Human Disease. (pp. 273-301) edited by Nigel M. Hooper and Uwe Lendeckel. Netherlands: Springer. doi: 10.1007/978-1-4020-6372-5_13

Amylose Affinity Chromatography of Maltose-Binding Protein: Purification by both Native and Novel Matrix-Assisted Dialysis-Refolding Methods

Pattenden, Leonard K. and Thomas, Walter G. (2007). Amylose Affinity Chromatography of Maltose-Binding Protein: Purification by both Native and Novel Matrix-Assisted Dialysis-Refolding Methods. Affinity Chromatography: Methods and Protocols. (pp. 196-217) edited by Michael Zachariou. Totowa, NJ: Humana Press.

Angiotensin receptors in GtoPdb v.2023.1

Alexander, Wayne, Bernstein, Kenneth E., Catt, Kevin J., De Gasparo, Marc, Dhanachandra Singh, Khuraijam, Eguchi, Satoru, Escher, Emanuel, Goodfriend, Theodore L., Horiuchi, Mastgugu, Hunyady, László, Husain, Ahsan, Inagami, Tadashi, Karnik, Sadashiva, Kemp, Jacqueline, Thomas, Walter G., Timmermans, Pieter B. M. W. M., Tirupula, Kalyan, Unal, Hamiyet, Unger, Thomas and Vanderheyden, Patrick (2023). Angiotensin receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1). doi: 10.2218/gtopdb/f6/2023.1

Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways

Ashton, Kevin J., Kiessling, Can J., Thompson, Jamie-Lee M., Aziz, Aliah Y., Thomas, Walter G., Headrick, John P. and Reichelt, Melissa E. (2023). Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways. Experimental Gerontology, 171 112011, 112011. doi: 10.1016/j.exger.2022.112011

Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1

Mohamed, Raafat, Shajimoon, Aravindra, Afroz, Rizwana, Gabr, Mai, Thomas, Wally, Little, Peter J. and Kamato, Danielle (2022). Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1. The FEBS Journal, 289 (9), 2642-2656. doi: 10.1111/febs.16297

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

Eagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119

Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017))

O'Brien, Shannon L., Johnstone, Elizabeth K.M., Devost, Dominic, Conroy, Jacinta, Reichelt, Melissa E., Purdue, Brooke W., Ayoub, Mohammed A., Kawai, Tatsuo, Inoue, Asuka, Eguchi, Satoru, Hébert, Terence E., Pfleger, Kevin D.G. and Thomas, Walter G. (2021). Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017)). Biochemical Pharmacology, 192 114756, 114756. doi: 10.1016/j.bcp.2021.114756

Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury

Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Alzubaidi, Mubarak A.H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E., Thomas, Walter G. ... Palpant, Nathan J. (2021). Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury. Circulation , 144 (12), 947-960. doi: 10.1161/circulationaha.121.054360

The concise guide to pharmacology 2021/22: G protein‐coupled receptors

Alexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538

Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection

Sinclair, Jane E., Bloxham, Conor J., Chiu, Han, Chew, Keng Yih, Russell, Jake, Yoshikawa, Yusuke, Bielefeldt-Ohmann, Helle, Steele, Lauren E., Hulme, Katina D., Verzele, Nathalie A. J., Noye, Ellesandra C., Wu, Melanie, Reichelt, Melissa E., Thomas, Walter G., Gallo, Linda A., Redd, Meredith A. and Short, Kirsty R. (2021). Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection. Frontiers in Cellular and Infection Microbiology, 11 714440, 714440. doi: 10.3389/fcimb.2021.714440

Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy

Wang, Zhen, Chan, Hsiu‐Wen, Gambarotta, Giovanna, Smith, Nicola J., Purdue, Brooke W., Pennisi, David J., Porrello, Enzo R., O'Brien, Shannon L., Reichelt, Melissa E., Thomas, Walter G. and Paravicini, Tamara M. (2021). Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy. Journal of Cellular Physiology, 236 (12) jcp.30487, 8160-8170. doi: 10.1002/jcp.30487

Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners

Johnstone, Elizabeth K.M., Abhayawardana, Rekhati S., See, Heng B., Seeber, Ruth M., O'Brien, Shannon L., Thomas, Walter G. and Pfleger, Kevin D.G. (2021). Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners. Biochemical Pharmacology, 188 114521, 1-16. doi: 10.1016/j.bcp.2021.114521

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117

A high fat diet increases influenza A virus-associated cardiovascular damage

Siegers, Jurre Y., Novakovic, Boris, Hulme, Katina D., Marshall, Rebecca, Bloxham, Conor J., Thomas, Walter G., Reichelt, Mellissa E., Leijten, Lonneke, van Run, Peter, Knox, Karen, Sokolowski, Kamil A., Tse, Brian W. C., Chew, Keng Yih, Christ, Angelika N., Howe, Greg, Bruxner, Timothy J. C., Karolyi, Mario, Pawelka, Erich, Koch, Rebecca M., Bellmann-Weiler, Rosa, Burkert, Francesco, Weiss, Günter, Samanta, Romit J., Openshaw, Peter J. M., Bielefeldt-Ohmann, Helle, van Riel, Debby and Short, Kirsty R. (2020). A high fat diet increases influenza A virus-associated cardiovascular damage. The Journal of infectious diseases, 222 (5), 820-831. doi: 10.1093/infdis/jiaa159

A bitter taste in your heart

Bloxham, Conor J., Foster, Simon R. and Thomas, Walter G. (2020). A bitter taste in your heart. Frontiers in Physiology, 11 431, 431. doi: 10.3389/fphys.2020.00431

The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors

Alexander, Stephen P. H., Christopoulos, Arthur, Davenport, Anthony P., Kelly, Eamonn, Mathie, Alistair, Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Davies, Jamie A., Abbracchio, Maria P., Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Catt, Kevin J. ... Yao, Chengcan (2019). The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors. British Journal of Pharmacology, 176 (S1), S21-S141. doi: 10.1111/bph.14748

Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors

Ragnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2019). Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors. Science Signaling, 12 (572) eaas9485, eaas9485. doi: 10.1126/scisignal.aas9485

BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes

O'Brien, Shannon L., Johnstone, Elizabeth K. M., Devost, Dominic, Conroy, Jacinta, Reichelt, Melissa E., Purdue, Brooke W., Ayoub, Mohammed A., Kawai, Tatsuo, Inoue, Asuka, Eguchi, Satoru, Hébert, Terence E., Pfleger, Kevin D.G. and Thomas, Walter G. (2018). BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes. Biochemical Pharmacology, 158, 232-242. doi: 10.1016/j.bcp.2018.10.017

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Mills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114

Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity

Kaakinen, Mika, Reichelt, Melissa E., Ma, Zhibin, Ferguson, Charles, Martel, Nick, Porrello, Enzo R., Hudson, James E., Thomas, Walter G., Parton, Robert G. and Headrick, John P. (2017). Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity. Basic Research in Cardiology, 112 (3) 24, 24. doi: 10.1007/s00395-017-0613-6

Gaq proteins: molecular pharmacology and therapeutic potential

Kamato, Danielle, Mitra, Partha, Davis, Felicity, Osman, Narin, Chaplin, Rebecca, Cabot, Peter J., Afroz, Rizwana, Thomas, Walter, Zheng, Wenhua, Kaur, Harveen, Brimble, Margaret and Little, Peter J. (2017). Gaq proteins: molecular pharmacology and therapeutic potential. Cellular and Molecular Life Sciences, 74 (8), 1379-1390. doi: 10.1007/s00018-016-2405-9

CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis

Iyer, Swati, Chhabra, Yash, Harvey, Tracey J., Wang, Richard, Chiu, Han Sheng, Smith, A. G., Thomas, Walter G., Pennisi, David J. and Piper, Michael (2017). CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis. Journal of Molecular Histology, 48 (1), 53-61. doi: 10.1007/s10735-016-9702-3

Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection

Reichelt, Melissa E., O'Brien, Shannon, Thomas, Walter G. and Headrick, John P. (2017). Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection. International Journal of Biochemistry and Cell Biology, 83, 97-110. doi: 10.1016/j.biocel.2016.12.014

Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling

Little, P. J., Hollenberg, M. D, Kamato, D., Thomas, W., Chen, J., Wang, T., Zheng, W. and Osman, N. (2016). Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling. British Journal of Pharmacology, 173 (20), 2992-3000. doi: 10.1111/bph.13398

Crim1 has cell-autonomous and paracrine roles during embryonic heart development

Iyer, Swati, Chou, Fang Yu, Wang, Richard, Chiu, Han Sheng, Raju, Vinay K. Sundar, Little, Melissa H., Thomas, Walter G., Piper, Michael and Pennisi, David J. (2016). Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Scientific Reports, 6 (1) 19832, 19832 .1-19832 .15. doi: 10.1038/srep19832

Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular system

Forrester, Steven J., Kawai, Tatsuo, O'Brien, Shannon, Thomas, Walter, Harris, Raymond C. and Eguchi, Satoru (2016). Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular system. Annual Review of Pharmacology and Toxicology, 56 (1), 627-653. doi: 10.1146/annurev-pharmtox-070115-095427

Taste and hypertension in humans: targeting cardiovascular disease

Roura, Eugeni, Foster, Simon, Winklebach, Anja, Navarro, Marta, Thomas, Walter, Campbell, Katrina and Stowasser, Michael (2016). Taste and hypertension in humans: targeting cardiovascular disease. Current Pharmaceutical Design, 22 (15), 2290-2305. doi: 10.2174/1381612822666160216151545

Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulis

Karnik, Sadashiva S., Unal, Hamiyet, Kemp, Jacqueline R., Tirupula, Kalyan C., Eguchi, Satoru, Vanderheyden, Patrick M. L. and Thomas, Walter G. (2015). Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulis. Pharmacological Reviews, 67 (4), 754-819. doi: 10.1124/pr.114.010454

Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activation

Roura, Eugeni, Aldayyani, Asya, Thavaraj, Pridhuvi, Prakash, Sangeeta, Greenway, Delma, Thomas, Walter G., Meyerhof, Wolfgang, Roudnitzky, Natacha and Foster, Simon R. (2015). Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activation. Chemical Senses, 40 (6), 427-435. doi: 10.1093/chemse/bjv024

Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertion

Hirst, Daniel J., Lee, Tzong-Hsien, Pattenden, Leonard K., Thomas, Walter G. and Aguilar, Marie-Isabel (2015). Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertion. Scientific Reports, 5 (1) 9972, 1-14. doi: 10.1038/srep09972

Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation

Foster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, Dos Remedios, Cristobal G., Thomas, Walter G. and Ramialison, Mirana (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10) 1118, 1009-1027. doi: 10.1007/s00210-015-1118-1

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2

Clayton, Daniel, Hanchapola, Iresha, Thomas, Walter G., Widdop, Robert E., Smith, Alexander I., Perlmutter, Patrick and Aguilar, Marie-Isabel (2015). Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2. Frontiers in Pharmacology, 6 (JAN) 05, 5.1-5.9. doi: 10.3389/fphar.2015.00005

G protein-coupled receptors in cardiac biology: old and new receptors

Foster, Simon R, Roura, Eugeni, Molenaar, Peter and Thomas, Walter G. (2015). G protein-coupled receptors in cardiac biology: old and new receptors. Biophysical Reviews, 7 (1), 77-89. doi: 10.1007/s12551-014-0154-2

Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functions

Ragnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2015). Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functions. Molecular Pharmacology, 87 (1), 121-129. doi: 10.1124/mol.114.094557

Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart

Foster, Simon R., Blank, Kristina, See Hoe, Louise E., Behrens, Maik, Meyerhof, Wolfgang, Peart, Jason N. and Thomas, Walter G. (2014). Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart. FASEB Journal, 28 (10), 4497-4508. doi: 10.1096/fj.14-256305

Extrasensory perception: odorant and taste receptors beyond the nose and mouth

Foster, Simon R., Roura, Eugeni and Thomas, Walter G. (2014). Extrasensory perception: odorant and taste receptors beyond the nose and mouth. Pharmacology and Therapeutics, 142 (1), 41-61. doi: 10.1016/j.pharmthera.2013.11.004

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation

George, Amee J., Purdue, Brooke W., Gould, Cathryn M., Thomas, Daniel W., Handoko, Yanny, Qian, Hongwei, Quaife-Ryan, Gregory A., Morgan, Kylie A., Simpson, Kaylene J., Thomas, Walter G. and Hannan, Ross D. (2013). A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation. Journal of Cell Science, 126 (23), 5377-5390. doi: 10.1242/jcs.128280

Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart

Foster, Simon R., Porrello, Enzo R., Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D., Moritz, Karen M., Simmons, David G., Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang and Thomas, Walter G. (2013). Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart. PLoS ONE, 8 (5) e64579, e64579-1-e64579-10. doi: 10.1371/journal.pone.0064579

PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus

Wang, Xiao, Wang, Lingdi, Zhu, Lu, Pan, Yi, Xiao, Fei, Liu, Weizhong, Wang, Zhenzhen, Guo, Feifan, Liu, Yong, Thomas, Walter G. and Chen, Yan (2013). PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus. Diabetes, 62 (2), 444-456. doi: 10.2337/db12-0244

Angiotensin 1A receptors transfected into caudal ventrolateral medulla inhibit baroreflex gain and stress responses

Palma-Rigo, Kesia, Bassi, Jaspreet K., Nguyen-Huu, Thu-Phuc, Jackson, Kristy L., Davern, Pamela J., Chen, Daian, Elghozi, Jean-Luc, Thomas, Walter G., Allen, Andrew M. and Head, Geoffrey A. (2012). Angiotensin 1A receptors transfected into caudal ventrolateral medulla inhibit baroreflex gain and stress responses. Cardiovascular Research, 96 (2), 330-339. doi: 10.1093/cvr/cvs252

Efferent projections of C3 adrenergic neurons in the rat central nervous system

Sevigny, Charles P., Bassi, Jaspreet, Williams, David A., Anderson, Colin R., Thomas, Walter G. and Allen, Andrew M. (2012). Efferent projections of C3 adrenergic neurons in the rat central nervous system. Journal of Comparative Neurology, 520 (11), 2352-2368. doi: 10.1002/cne.23041

Silencing relaxin-3 in nucleus incertus of adult rodents: A viral vector-based approach to investigate neuropeptide function

Callander, Gabrielle E., Ma, Sherie, Ganella, Despina E., Wimmer, Verena C., Gundlach, Andrew L., Thomas, Walter G. and Bathgate, Ross A. D. (2012). Silencing relaxin-3 in nucleus incertus of adult rodents: A viral vector-based approach to investigate neuropeptide function. PLoS One, 7 (8 Article. No.e42300) e42300, e42300. doi: 10.1371/journal.pone.0042300

Real-time measurement of F-Actin remodelling during exocytosis using Lifeact-EGFP transgenic animals

Jang, Yujin, Soekmadji, Carolina, Mitchell, Justin M., Thomas, Walter G. and Thorn, Peter (2012). Real-time measurement of F-Actin remodelling during exocytosis using Lifeact-EGFP transgenic animals. Plos One, 7 (7) e39815, e39815.1-e39815.7. doi: 10.1371/journal.pone.0039815

PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus

Jin, Ting, Ding, Quirong, Huang, Heng, Xu, Daqian, Jiang, Yuhui, Zhou, Ben, Li, Zhenghu, Jiang, Xiaomeng, He, Jing, Liu, Weizhong, Zhang, Yixuan, Pan, Yi, Wang, Zhezhen, Thomas, Walter G. and Chen, Yan (2012). PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus. Cell Research, 22 (4), 661-676. doi: 10.1038/cr.2011.161

Angiotensin type 1A receptors in C1 neurons of the rostral ventrolateral medulla modulate the pressor response to aversive stress

Chen, Daian, Jancovski, Nikola, Bassi, Jaspreet K., Nguyen-Huu, Thu-Phuc, Choong, Yan-Ting, Palma-Rigo, Kesia, Davern, Pamela J., Gurley, Susan B., Thomas, Walter G., Head, Geoffrey A. and Allen, Andrew M. (2012). Angiotensin type 1A receptors in C1 neurons of the rostral ventrolateral medulla modulate the pressor response to aversive stress. Journal of Neuroscience, 32 (6), 2051-2061. doi: 10.1523/JNEUROSCI.5360-11.2012

Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles

Porrello, Enzo R., Pfleger, Kevin D. G., Seeber, Ruth M., Qian, Hongwei, Oro, Cristina, Abogadie, Fe, Delbridge, Lea M. D. and Thomas, Walter G. (2011). Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles. Cellular Signalling, 23 (11), 1767-1776. doi: 10.1016/j.cellsig.2011.06.011

Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures

O'Callaghan, E.L., Bassi, J.K., Porrello, E.R., Delbridge, L.M.D., Thomas, W.G. and Allen, A.M. (2011). Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures. Journal of Neurochemistry, 119 (1), 18-26. doi: 10.1111/j.1471-4159.2011.07406.x

Relative affinity of angiotensin peptides and novel ligands at AT(1) and AT(2) receptors

Bosnyak, Sanja, Jones, Emma S., Christopoulos, Arthur, Aguilar, Marie-Isabel, Thomas, Walter G. and Widdop, Robert E. (2011). Relative affinity of angiotensin peptides and novel ligands at AT(1) and AT(2) receptors. Clinical Science, 121 (7), 297-303. doi: 10.1042/CS20110036

Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy

Smith, Nicola J., Chan, Hsiu-Wen, Qian, Hongwei, Bourne, Allison M., Hannan, Katherine M, Warner, Fiona J., Ritchie, Rebecca H., Pearson, Richard B., Hannan, Ross D. and Thomas, Walter G. (2011). Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy. Hypertension, 57 (5), 973-980. doi: 10.1161/HYPERTENSIONAHA.110.166710

A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function

Jones, Emma S., Del Borgo, Mark P., Kirsch, Julian F., Clayton, Daniel, Bosnyak, Sanja, Welungoda, Iresha, Hausler, Nicholas, Unabia, Sharon, Perlmutter, Patrick, Thomas, Walter G., Aguilar, Marie-Isabel and Widdop, Robert E. (2011). A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function. Hypertension, 57 (3 Part 2), 570-576. doi: 10.1161/HYPERTENSIONAHA.110.164301

The renin-angiotensin system and cancer: Old dog, new tricks

George, AJ, Thomas, WG and Hannan, RD (2010). The renin-angiotensin system and cancer: Old dog, new tricks. Nature Reviews Cancer, 10 (11), 745-759. doi: 10.1038/nrc2945

Ligand-supported purification of the urotensin-II receptor

Du, Ann T., Onan, Döne, Dinh, Diem T., Lew, Michael J., Ziogas, James, Aguilar, Marie-Isabel, Pattenden, Leonard K. and Thomas, Walter G. (2010). Ligand-supported purification of the urotensin-II receptor. Molecular Pharmacology, 78 (4), 639-647. doi: 10.1124/mol.110.065151

Expression of angiotensin type 1A receptors in C1 neurons restores the sympathoexcitation to angiotensin in the rostral ventrolateral medulla of angiotensin type 1A knockout mice

Chen, DA, Bassi, JK, Walther, T, Thomas, WG and Allen, AM (2010). Expression of angiotensin type 1A receptors in C1 neurons restores the sympathoexcitation to angiotensin in the rostral ventrolateral medulla of angiotensin type 1A knockout mice. Hypertension, 56 (1), 143-150. doi: 10.1161/HYPERTENSIONAHA.110.151704

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012

Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors

Porrello, Enzo R, Meeker, William F, Thomas, Walter G, Widdop, Robert E and Delbridge, Lea MD (2009). Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors. Neonatology, 97 (3), 257-265. doi: 10.1159/000253757

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL

Ballinger, M. L., Ivey, M. E., Osman, N., Thomas, W. G. and Little, P. J. (2009). Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL. Atherosclerosis, 205 (2), 451-457. doi: 10.1016/j.atherosclerosis.2009.01.024

Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment

Callander, Gabrielle E., Thomas, Walter G. and Bathgate, Ross A. D. (2009). Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment. American Journal of Physiology - Cell Physiology, 296 (5), C1058-C1066. doi: 10.1152/ajpcell.00581.2008

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

Drew, Brian G., Duffy, Stephen J., Formosa, Melissa F., Natoli, Alaina K., Henstridge, Darren C., Penfold, Sally A., Thomas, Walter G., Mukhamedova, Nigora, de Courten, Barbora, Forbes, Josephine M., Yap, Felicia Y., Kaye, David M., van Hall, Gerrit, Febbraio, Mark A., Kemp, Bruce E., Sviridov, Dmitri, Steinberg, Gregory R. and Kingwell, Bronwyn A. (2009). High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation, 119 (15), 2103-2111. doi: 10.1161/CIRCULATIONAHA.108.843219

Development and Optimization of MicroRNA against Relaxin-3

Callander, G. E., Thomas, W. G. and Bathgate, R. A. D. (2009). Development and Optimization of MicroRNA against Relaxin-3. Annals of the New York Academy of Sciences, 1160 (Relaxin and Related Peptides: Fifth International Conference), 261-264. doi: 10.1111/j.1749-6632.2008.03816.x

Role of helix 8 in G protein-coupled receptors based on structure-function studies on the type 1 angiotensin receptor

Huynh, J., Thomas, W. G., Aguilar, M. I. and Pattenden, L. K. (2009). Role of helix 8 in G protein-coupled receptors based on structure-function studies on the type 1 angiotensin receptor. Molecular and Cellular Endocrinology, 302 (2), 118-127. doi: 10.1016/j.mce.2009.01.002

Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II

Aranguiz-Urroz, Pablo, Soto, Dagoberto, Contreras, Ariel, Troncoso, Rodrigo, Chiong, Mario, Montenegro, Jose, Venegas, Daniel, Smolic, Christian, Ayala, Pedro, Thomas, Walter G., Lavandero, Sergio and Diaz-Araya, Guillermo (2009). Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II. American Journal of Hypertension, 22 (5), 569-576. doi: 10.1038/ajh.2009.32

Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction

Porrello, Enzo R., Bell, James R., Schertzer, Jonathan D., Curl, Claire L., McMullen, Julie R., Mellor, Kimberley M., Ritchie, Rebecca H., Lynch, Gordon S., Harrap, Stephen B., Thomas, Walter G. and Delbridge, Lea M. D. (2009). Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 296 (3), R672-R680. doi: 10.1152/ajpregu.90919.2008

Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor-Mediated Cardiomyocyte Autophagy

Porrello, Enzo R., D'Amore, Angelo, Curl, Claire L., Allen, Andrew M., Harrap, Stephen B., Thomas, Walter G. and Delbridge, Lea M. D. (2009). Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor-Mediated Cardiomyocyte Autophagy. Hypertension, 53 (6), 1032-1040. doi: 10.1161/HYPERTENSIONAHA.108.128488

The angiotensin II type 2 (AT(2)) receptor: an enigmatic seven transmembrane receptor

Porrello, Enzo R., Delbridge, Lea M. D. and Thomas, Walter G. (2009). The angiotensin II type 2 (AT(2)) receptor: an enigmatic seven transmembrane receptor. Frontiers in Bioscience, 14 (3), 958-972. doi: 10.2741/3289

UBF levels determine the number of active ribosomal RNA genes in mammals

Sanij, Elaine, Poortinga, Gretchen, Sharkey, Kerith, Hung, Sandy, Holloway, Timothy P., Ouin, Jaclyn, Robb, Elysia, Wong, Lee H., Thomas, Walter G., Stefanovsky, Victor, Moss, Tom, Rothblum, Lawrence, Hannan, Katherine M., McArthur, Grant A., Pearson, Richard B. and Hannan, Ross D. (2008). UBF levels determine the number of active ribosomal RNA genes in mammals. The Journal of Cell Biology, 183 (7), 1259-1274. doi: 10.1083/jcb.200805146

Phospholipase C/Protein kinase C pathway Mediates Angiotensin ll-Dependent Apoptosis in Neonatal Rat cardiac Fibroblasts Expressing AT1 Receptor

Vivar, Raul, Soto, C, Copaja, M, Mateluna, F, Aranguiz, P, Munoz, J P, Chiong, M, Garcia, L, Letelier, A, Thomas, W G, Lavandero, S and Diaz-Araya, G (2008). Phospholipase C/Protein kinase C pathway Mediates Angiotensin ll-Dependent Apoptosis in Neonatal Rat cardiac Fibroblasts Expressing AT1 Receptor. Journal of Cardiovascular Pharmacology, 52 (2), 184-190. doi: 10.1097/FJC.0b013e318181fadd

Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis

Bathgate, R. A. D., Lekgabe, E. D., McGuane, J. T., Su, Y., Pham, T., Ferraro, T., Layfield, S., Hannan, R. D., Thomas, W. G., Samuel, C. S. and Du, X.-J. (2008). Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis. Molecular and Cellular Endocrinology, 280 (1-2), 30-38. doi: 10.1016/j.mce.2007.09.008

Amylose affinity chromatography of maltose-binding protein: Purification by both native and novel matrix-assisted dialysis refolding methods

Pattenden, Leonard K. and Thomas, Walter G. (2007). Amylose affinity chromatography of maltose-binding protein: Purification by both native and novel matrix-assisted dialysis refolding methods. Methods in Molecular Biology, 421, 169-189.

Type 1 angiotensin receptor pharmacology: Signaling beyond G proteins

Oro, Cristina, Qian, Hongwei and Thomas, Walter G. (2007). Type 1 angiotensin receptor pharmacology: Signaling beyond G proteins. Pharmacology & Therapeutics, 113 (1), 210-226. doi: 10.1016/j.pharmthera.2006.10.001

Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy

Chan, Hsiu-Wen, Jenkins, Anna, Pipolo, Luisa, Hannan, Ross D., Thomas, Walter G. and Smith, Nicola J. (2006). Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy. Journal of Receptor Signal Transduction, 26 (5-6), 659-677. doi: 10.1080/10799890600923187

Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein–protein interactions in live cells

Pfleger, Kevin D. G., Dromey, Jasmin R., Dalrymple, Matthew B., Lim, Esther M. L., Thomas, Walter G. and Eidne, Karin A. (2006). Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein–protein interactions in live cells. Cellular Signalling, 18 (10), 1664-1670. doi: 10.1016/j.cellsig.2006.01.004

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

Carey, Andrew L., Steinberg, Gregory R., Macaulay, S. Lance, Thomas, Walter G., Holmes, Anna G., Ramm, Georg, Prelovsek, Oja, Hohnen-Behrens, Cordula, Watt, Matthew J., James, David E., Kemp, Bruce E., Pedersen, Bente K. and Febbraio, Mark A. (2006). Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes, 55 (10), 2688-2697. doi: 10.2337/db05-1404

Protein kinase C regulates the cell surface activity of endothelin-converting enzyme-1

Smith, Ian, Lew, Rebecca, Thomas, Walter G. and Tochon-Danguy, Nathalie (2006). Protein kinase C regulates the cell surface activity of endothelin-converting enzyme-1. International journal of peptide research and therapeutics, 12 (3), 291-295. doi: 10.1007/s10989-006-9034-3

Role of angiotensin II type 1A receptor phosphorylation, phospholipase D, and extracellular calcium in isoform-specific protein kinase C membrane translocation responses

Policha, Aleksandra, Daneshtalab, Noriko, Chen, Lina, Dale, Lianne B., Altier, Christophe, Khosravani, Houman, Thomas, Walter G., Zamponi, Gerald W. and Ferguson, Stephen S. G. (2006). Role of angiotensin II type 1A receptor phosphorylation, phospholipase D, and extracellular calcium in isoform-specific protein kinase C membrane translocation responses. The Journal of Biological Chemistry, 281 (36), 26340-26349. doi: 10.1074/jbc.M605437200

Baroreceptor reflex stimulation does not induce cytomegalovirus promoter-driven transgene expression in the ventrolateral medulla in vivo

Allen, Andrew M., Dosanjh, Jaspreet, Dassanayake, Sashikala, Tan, Geraldine and Thomas, Walter G. (2006). Baroreceptor reflex stimulation does not induce cytomegalovirus promoter-driven transgene expression in the ventrolateral medulla in vivo. Autonomic Neuroscience: Basic and Clinical, 126-127, 150-155. doi: 10.1016/j.autneu.2006.02.024

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK

Watt, Matthew J., Dzamko, Nicolas, Thomas, Walter G., Rose-John, Stefan, Ernst, Matthias, Carling, David, Kemp, Bruce E., Febbraio, Mark A. and Steinberg, Gregory R. (2006). CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nature Medicine, 12 (5), 541-548. doi: 10.1038/nm1383

Fine mapping of Lvm1: a quantitative trait locus controlling heart size independently of blood pressure

Di Nicolantonio, R., Kostka, V., Kwitek, A., Jacob, H., Thomas, W. G. and Harrap, S. B. (2006). Fine mapping of Lvm1: a quantitative trait locus controlling heart size independently of blood pressure. Pulmonary Pharmacology & Therapeutics, 19 (1), 70-73. doi: 10.1016/j.pupt.2005.02.010

Tackling the EGFR in pathological tissue remodelling

Chan, Hsiu-Wen, Smith, Nicola J., Hannan, Ross D. and Thomas, Walter G. (2006). Tackling the EGFR in pathological tissue remodelling. Pulmonary Pharmacology and Therapeutics, 19 (1), 74-78. doi: 10.1016/j.pupt.2005.04.005

Expression of Constitutively Active Angiotensin Receptors in the Rostral Ventrolateral Medulla Increases Blood Pressure

Allen, A. M., Dosanjh, J. K., Erac, M., Dassanayake, S., Hannan, R. D. and Thomas, W. G. (2006). Expression of Constitutively Active Angiotensin Receptors in the Rostral Ventrolateral Medulla Increases Blood Pressure. Hypertension, 47 (6), 1054-1061. doi: 10.1161/01.HYP.0000218576.36574.54

Post-natal cardiac development in an experimental model of normotensive cardiac hypertrophy

Porrello, E. R., Curl, C. L., Harrap, S. B., Thomas, W. G. and Delbridge, L. M. D. (2006). Post-natal cardiac development in an experimental model of normotensive cardiac hypertrophy. Journal of Molecular and Cellular Cardiology, 41 (4), 744-744. doi: 10.1016/j.yjmcc.2006.06.047

The Angiotensin II Type 2 Receptor Causes Constitutive Growth of Cardiomyocytes and Does Not Antagonize Angiotensin II Type 1 Receptor–Mediated Hypertrophy

D’Amore, Angelo, Black, M. Jane and Thomas, Walter G. (2005). The Angiotensin II Type 2 Receptor Causes Constitutive Growth of Cardiomyocytes and Does Not Antagonize Angiotensin II Type 1 Receptor–Mediated Hypertrophy. Hypertension, 46 (6), 1347-1354. doi: 10.1161/01.HYP.0000193504.51489.cf

Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts

Corstius, Hugo Brandt, Zimanyi, Monika A., Maka, Noori, Herath, Thiloshini, Thomas, Walter, Van Der Laarse, Arnoud, Wreford, Nigel G. and Black, M. Jane (2005). Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatric Research, 57 (6), 796-800. doi: 10.1203/01.PDR.0000157726.65492.CD

G Protein Coupling and Second Messenger Generation Are Indispensable for Metalloprotease-dependent, Heparin-binding Epidermal Growth Factor Shedding Through Angiotensin II Type-1 Receptor

Mifune, M., Ohtsu, H., Suzuki, H., Nakashima, H., Brailoiu, E., Dun, N. J., Frank, G. D., Inagami, T., Higashiyama, S., Thomas, W. G., Eckhart, A. D., Dempsey, P. J. and Eguchi, S. (2005). G Protein Coupling and Second Messenger Generation Are Indispensable for Metalloprotease-dependent, Heparin-binding Epidermal Growth Factor Shedding Through Angiotensin II Type-1 Receptor. Journal of Biological Chemistry, 280 (28), 26592-26599. doi: 10.1074/jbc.M502906200

Double Trouble for Type 1 Angiotensin Receptors in Atherosclerosis

Thomas, Walter G (2005). Double Trouble for Type 1 Angiotensin Receptors in Atherosclerosis. New England Journal of Medicine, 352 (5), 506-508. doi: 10.1056/NEJMcibr043928

Helix I of β-Arrestin Is Involved in Postendocytic Trafficking but Is Not Required for Membrane Translocation, Receptor Binding, and Internalization

Dinh, Diem T., Qian, Hongwei, Seeber, Ruth, Lim, Esther, Pfleger, Kevin, Eidne, Karin A. and Thomas, Walter G. (2005). Helix I of β-Arrestin Is Involved in Postendocytic Trafficking but Is Not Required for Membrane Translocation, Receptor Binding, and Internalization. Molecular Pharmacology, 67 (2), 375-382. doi: 10.1124/mol.104.004721

Dual Pathways for Nuclear Factor kB Activation by Angiotensin II in Vascular Smooth Muscle Phosphorylation of p65 by IkB Kinase and Ribosomal Kinase

Zhang, Liping, Cheng, Jizhong, Ma, Yewei, Thomas, Walter, Zhang, Jiqiang and Du, Jie (2005). Dual Pathways for Nuclear Factor kB Activation by Angiotensin II in Vascular Smooth Muscle Phosphorylation of p65 by IkB Kinase and Ribosomal Kinase. Circulation Research, 97 (10), 975-982. doi: 10.1161/01.RES.0000190589.52286.41

Evaluation of the membrane-binding properties of the proximal region of the angiotensin II receptor (AT1A) carboxyl terminus by surface plasmon resonance

Kamimori, Hiroshi, Unabia, Sharon, Thomas, Walter G. and Aguilar, Marie-Isabel (2005). Evaluation of the membrane-binding properties of the proximal region of the angiotensin II receptor (AT1A) carboxyl terminus by surface plasmon resonance. Analytical Sciences, 21 (2), 171-174. doi: 10.2116/analsci.21.171

Hijacking epidermal growth factor receptors by angiotensin II: New possibilities for understanding and treating cardiac hypertrophy

Smith N. J., Chan, H.-W., Osborne, J. E., Thomas, W. G. and Hannan, R. D. (2004). Hijacking epidermal growth factor receptors by angiotensin II: New possibilities for understanding and treating cardiac hypertrophy. Cellular and Molecular Life Sciences, 61 (21), 2695-2703. doi: 10.1007/s00018-004-4244-3

p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat

See, Fiona, Thomas, Walter, Way, Kerrie, Tzanidis, Alex, Kompa, Andrew, Lewis, Dion, Itescu, Silviu and Krum, Henry (2004). p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat. Journal of the American College of Cardiology, 44 (8), 1679-1689. doi: 10.1016/j.jacc.2004.07.038

Cardiovascular Role of Urotensin II: Effect of Chronic Infusion in the Rat

Kompa, A. R., Thomas, W. G., See, F., Tzanidis, A., Hannan, R. D. and Krum, H. (2004). Cardiovascular Role of Urotensin II: Effect of Chronic Infusion in the Rat. Peptides, 25 (10), 1783-1788. doi: 10.1016/j.peptides.2004.03.029

Agonist-dependent internalization of the angiotensin II type one receptor (AT1): role of C-terminus phosphorylation in recruitment of β-arrestins

Kule, Chris E., Karoor, Vijaya, Day, Jonathan N. E., Thomas, Walter G., Baker, Kenneth M., Dinh, Diem, Acker, Kathleen A. and Booz, George W. (2004). Agonist-dependent internalization of the angiotensin II type one receptor (AT1): role of C-terminus phosphorylation in recruitment of β-arrestins. Regulatory Peptides, 120 (1-3), 141-148. doi: 10.1016/j.regpep.2004.03.001

Urotensin II: the old kid in town

Onan, Döne, Hannan, Ross D. and Thomas, Walter G. (2004). Urotensin II: the old kid in town. Trends in Endocrinology and Metabolism, 15 (4), 175-182. doi: 10.1016/j.tem.2004.03.007

Urotensin II Promotes Hypertrophy of Cardiac Myocytes via Mitogen-Activated Protein Kinases

Onan, Done, Pipolo, Luisa, Yang, Eunice, Hannan, Ross D. and Thomas, Walter G. (2004). Urotensin II Promotes Hypertrophy of Cardiac Myocytes via Mitogen-Activated Protein Kinases. Molecular Endocrinology, 18 (9), 2344-2354. doi: 10.1210/me.2003-0309

When 6 is 9: ‘Uncoupled’ AT 1 receptors turn signalling on its head

Thomas, W. G., Qian, H. and Smith, N. J. (2004). When 6 is 9: ‘Uncoupled’ AT 1 receptors turn signalling on its head. Cellular and Molecular Life Sciences, 61 (21), 2687-2694. doi: 10.1007/s00018-004-4245-2

Direct Actions of Urotensin II on the Heart Implications for Cardiac Fibrosis and Hypertrophy

Tzanidis, Alex, Hannan, Ross D., Thomas, Walter G., Onan, Döne, Autelitano, Dominic J., See, Fiona, Kelly, Darren J., Gilbert, Richard E. and Krum, Henry (2003). Direct Actions of Urotensin II on the Heart Implications for Cardiac Fibrosis and Hypertrophy. Circulation Research, 93 (3), 246-253. doi: 10.1161/01.RES.0000084382.64418.BC

Angiotensin receptors: form and function and distribution

Thomas, Walter G. and Mendelsohn, Frederick A. O. (2003). Angiotensin receptors: form and function and distribution. International journal of biochemistry & cell biology, 35 (6), 774-779. doi: 10.1016/S1357-2725(02)00263-7

Adrenomedullin inhibits angiotensin AT1A receptor expression and function in cardiac fibroblasts

Autelitano, Dominic J., Ridings, Rebecca, Pipolo, Luisa and Thomas, Walter G. (2003). Adrenomedullin inhibits angiotensin AT1A receptor expression and function in cardiac fibroblasts. Regulatory Peptides, 112 (1-3), 131-137. doi: 10.1016/S0167-0115(03)00031-4

Arresting angiotensin type 1 receptors

Thomas, Walter G. and Qian, Hongwei (2003). Arresting angiotensin type 1 receptors. Trends in Endocrinology & Metabolism, 14 (3), 130-136. doi: 10.1016/S1043-2760(03)00023-7

Surface plasmon resonance spectroscopy in the study of membrane-mediated cell signalling

Mozsolits, Henriette, Thomas, Walter G. and Aguilar, Marie-Isabel (2003). Surface plasmon resonance spectroscopy in the study of membrane-mediated cell signalling. Journal of peptide science, 9 (2), 77-89. doi: 10.1002/psc.439

Angiotensin II mediates cardiomyocyte hypertrophic growth pathways via MMP-dependent HB-EGF liberation

Smith, Nicola J., Hannan, Ross D., Thomas, Walter G. and Lew, Rebecca A. (2003). Angiotensin II mediates cardiomyocyte hypertrophic growth pathways via MMP-dependent HB-EGF liberation. Letters in Peptide Science, 10 (5), 431-435. doi: 10.1007/s10989-004-2398-3

Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane

Wyse, B. D., Prior, I. A., Qian, H. W., Morrow, I. C., Nixon, S., Muncke, C., Kurzchalia, T. V., Thomas, W. G., Parton, R. G. and Hancock, J. F. (2003). Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. Journal of Biological Chemistry, 278 (26), 23738-23746. doi: 10.1074/jbc.M212892200

Emerging Role of the Urotensin II System in Cardiovascular Disease

Krum, Henry, Kompa, Andrew, Hannan, Ross and Thomas, Walter (2003). Emerging Role of the Urotensin II System in Cardiovascular Disease. Heart Drug, 3 (3), 153-158. doi: 10.1159/000072742

Electrostatic and Hydrophobic Forces Tether the Proximal Region of the Angiotensin II Receptor (AT1A) Carboxyl Terminus to Anionic Lipids

Mozsolits, Henriette, Unabia, Sharon, Ahmad, Ariani, Morton, Craig J., Thomas, Walter G. and Aguilar, Marie-Isabel (2002). Electrostatic and Hydrophobic Forces Tether the Proximal Region of the Angiotensin II Receptor (AT1A) Carboxyl Terminus to Anionic Lipids. Biochemistry, 41 (24), 7830-7840. doi: 10.1021/bi0121813

Side-Chain Substitutions within Angiotensin II Reveal Different Requirements for Signaling, Internalization, and Phosphorylation of Type 1A Angiotensin Receptors

Holloway, Alice C., Qian, Hongwei, Pipolo, Luisa, Ziogas, James, Miura, Shin-ichiro, Karnik, Sadashiva, Southwell, Bridget R., Lew, Michael J. and Walter G. Thomas (2002). Side-Chain Substitutions within Angiotensin II Reveal Different Requirements for Signaling, Internalization, and Phosphorylation of Type 1A Angiotensin Receptors. Molecular pharmacology, 61 (4), 768-777. doi: 10.1124/mol.61.4.768

Adenoviral-Directed Expression of the Type 1A Angiotensin Receptor Promotes Cardiomyocyte Hypertrophy via Transactivation of the Epidermal Growth Factor Receptor.

Thomas, Walter G., Brandenburger, Yves, Autelitano, Dominic J., Pham, Thao, Qian, Hongwei and Hannan, Ross D. (2002). Adenoviral-Directed Expression of the Type 1A Angiotensin Receptor Promotes Cardiomyocyte Hypertrophy via Transactivation of the Epidermal Growth Factor Receptor.. Circulation research., 90 (2), 135-142. doi: 10.1161/hh0202.104109

Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia

Fabiani, M. E., Sourial, M., Thomas, W. G., Johnston, C. I. and Frauman, A. G. (2001). Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia. Journal of Endocrinology, 171 (1), 97-108. doi: 10.1677/joe.0.1710097

Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to β-arrestin-dependent internalization

Hanyaloglu, Aylin C., Vrecl, Milka, Kroeger, Karen M., Miles, Lauren E. C., Qian, Hongwei, Thomas, Walter G. and Eidne, Karin A. (2001). Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to β-arrestin-dependent internalization. Journal of Biological Chemistry, 276 (21), 18066-18074. doi: 10.1074/jbc.M009275200

Association of β-arrestin 1 with the type 1A angiotensin II receptor involves phosphorylation of the receptor carboxyl terminus and correlates with receptor internalization

Qian, HW, Pipolo, L and Thomas, WG (2001). Association of β-arrestin 1 with the type 1A angiotensin II receptor involves phosphorylation of the receptor carboxyl terminus and correlates with receptor internalization. Molecular Endocrinology, 15 (10), 1706-1719. doi: 10.1210/me.15.10.1706

Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state

Thomas, Walter G., Qian, Hongwei W., Chang, Chang-Sheng and Karnik, Sadashiva (2000). Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state. Journal of Biological Chemistry, 275 (4), 2893-2900. doi: 10.1074/jbc.275.4.2893

Identification of protein kinase C phosphorylation sites in the angiotensin II (AT(1A)) receptor

Qian, HW, Pipolo, L and Thomas, WG (1999). Identification of protein kinase C phosphorylation sites in the angiotensin II (AT(1A)) receptor. Biochemical Journal, 343 (3), 637-644. doi: 10.1042/0264-6021:3430637

New aspects of angiotensin receptor regulation: Implications for other seven transmembrane-spanning receptors.

Thomas, WG (1999). New aspects of angiotensin receptor regulation: Implications for other seven transmembrane-spanning receptors.. Protein and Peptide Letters, 6 (5), 305-317.

Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT(1A)) receptor

Thomas, WG, Pipolo, L and Qian, HW (1999). Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT(1A)) receptor. FEBS Letters, 455 (3), 367-371. doi: 10.1016/S0014-5793(99)00904-7

Regulation of angiotensin II type 1 (AT1) receptor function

Thomas, Walter G. (1999). Regulation of angiotensin II type 1 (AT1) receptor function. Regulatory Peptides, 79 (1), 9-23. doi: 10.1016/S0167-0115(98)00140-2

Phosphorylation of the angiotensin II (AT(1A)) receptor carboxyl terminus: A role in receptor endocytosis

Thomas, WG, Motel, TJ, Kule, CE, Karoor, V and Baker, KM (1998). Phosphorylation of the angiotensin II (AT(1A)) receptor carboxyl terminus: A role in receptor endocytosis. Molecular Endocrinology, 12 (10), 1513-1524. doi: 10.1210/me.12.10.1513

Functional role for the angiotensin II receptor (AT(1A)) 3 '-untranslated region in determining cellular responses to agonist: evidence for recognition by RNA binding proteins

Thekkumkara, TJ, Thomas, WG, Motel, TJ and Baker, KM (1998). Functional role for the angiotensin II receptor (AT(1A)) 3 '-untranslated region in determining cellular responses to agonist: evidence for recognition by RNA binding proteins. Biochemical Journal, 329 (2), 255-264. doi: 10.1042/bj3290255

Cardiac effects of AII: AT1A Receptor Signaling, Desensitization, and Internalization

Thomas, W. G., Thekkumkara, T. J. and Baker, K. M. (1996). Cardiac effects of AII: AT1A Receptor Signaling, Desensitization, and Internalization. Advances in Experimental Medicine and Biology, 396, 59-69.

Molecular mechanisms of angiotensin II (AT(1A)) receptor endocytosis

Thomas, WG, Thekkumkara, TJ and Baker, KM (1996). Molecular mechanisms of angiotensin II (AT(1A)) receptor endocytosis. Clinical and Experimental Pharmacology and Physiology, 23, S74-S80.

Evidence against a role for protein kinase C in the regulation of the angiotensin II (AT1A) receptor

Thomas, WG, Baker, KM, Booz, GW and Thekkumkara, TJ (1996). Evidence against a role for protein kinase C in the regulation of the angiotensin II (AT1A) receptor. European Journal of Pharmacology, 295 (1), 119-122. doi: 10.1016/0014-2999(95)00732-6

Molecular forms of rat angiotensinogen in plasma and brain: identification by isoelectric focusing and immunoblot analysis

Thomas, WG, Kerr, D and Sernia, C (1995). Molecular forms of rat angiotensinogen in plasma and brain: identification by isoelectric focusing and immunoblot analysis. Regulatory Peptides, 59 (1), 31-41. doi: 10.1016/0167-0115(95)00071-I

Angiotensin-Ii Receptor Endocytosis Involves 2 Distinct Regions Ef the Cytoplasmic Tail - a Role for Residues On the Hydrophobic Face of a Putative Amphipathic Helix

Thomas, WG, Baker, KM, Motel, TJ and Thekkumkara, TJ (1995). Angiotensin-Ii Receptor Endocytosis Involves 2 Distinct Regions Ef the Cytoplasmic Tail - a Role for Residues On the Hydrophobic Face of a Putative Amphipathic Helix. Journal of Biological Chemistry, 270 (38), 22153-22159. doi: 10.1074/jbc.270.38.22153

Activation of the Stat Pathway by Angiotensin-Ii in T3Cho/at(1A) Cells - Cross-Talk Between Angiotensin-Ii and Interleukin-6 Nuclear Signaling

Bhat, GJ, Thekkumkara, TJ, Thomas, WG, Conrad, KM and Baker, KM (1995). Activation of the Stat Pathway by Angiotensin-Ii in T3Cho/at(1A) Cells - Cross-Talk Between Angiotensin-Ii and Interleukin-6 Nuclear Signaling. Journal of Biological Chemistry, 270 (32), 19059-19065. doi: 10.1074/jbc.270.32.19059

Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization

Thomas, Walter G., Thekkumkara, Thomas J., Motel, Thomas J. and Baker, Kenneth M. (1995). Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization. Journal of Biological Chemistry, 270 (1), 207-213. doi: 10.1074/jbc.270.1.207

Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II

Thekkumkara, TJ, Du, J, Dostal, DE, Motel, TJ, Thomas, WG and Baker, KM (1995). Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II. Molecular and Cellular Biochemistry, 146 (1), 79-89. doi: 10.1007/BF00926885

Angiotensin II stimulates sis-inducing factor-like DNA binding activity: evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein

Bhat, G. Jayarama, Thekkumkara, Thomas J., Thomas, Walter G., Conrad, Kathleen M. and Baker, Kenneth M. (1994). Angiotensin II stimulates sis-inducing factor-like DNA binding activity: evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein. Journal of Biological Chemistry, 269 (50), 31443-31449.

A Novel Inhibitory Role for Glucocorticoids in the Secretion of Angiotensinogen by C6 Glioma-Cells

Sernia, C and Thomas, WG (1994). A Novel Inhibitory Role for Glucocorticoids in the Secretion of Angiotensinogen by C6 Glioma-Cells. Journal of Neurochemistry, 62 (4), 1296-1301. doi: 10.1046/j.1471-4159.1994.62041296.x

Angiotensinogen is secreted by pure rat neuronal cell cultures

Thomas, WG, Greenland, KJ, Shinkel, TA and Sernia, C (1992). Angiotensinogen is secreted by pure rat neuronal cell cultures. Brain Research, 588 (2), 191-200. doi: 10.1016/0006-8993(92)91575-Y

Angiotensinogen secretion by single rat pituitary cells: Detection by a reverse haemolytic plaque assay and cell identification by immunocytochemistry

Sernia, C, Shinkel, TA, Thomas, WG, Ho, Kky and Lincoln, D (1992). Angiotensinogen secretion by single rat pituitary cells: Detection by a reverse haemolytic plaque assay and cell identification by immunocytochemistry. Neuroendocrinology, 55 (3), 308-316. doi: 10.1159/000126130

Oxytocin Receptors in the Mammary-Gland and Reproductive-Tract of a Marsupial, the Brushtail Possum (Trichosurus-Vulpecula)

Sernia, C, Thomas, WG and Gemmell, RT (1991). Oxytocin Receptors in the Mammary-Gland and Reproductive-Tract of a Marsupial, the Brushtail Possum (Trichosurus-Vulpecula). Biology of Reproduction, 45 (5), 673-679. doi: 10.1095/biolreprod45.5.673

Effect of Intra-Ovarian Infusion of Oxytocin On Plasma Progesterone Concentrations in Pregnant Ewes

Sernia, C, Gemmell, RT and Thomas, WG (1991). Effect of Intra-Ovarian Infusion of Oxytocin On Plasma Progesterone Concentrations in Pregnant Ewes. Journal of Reproduction and Fertility, 92 (2), 453-460. doi: 10.1530/jrf.0.0920453

Immunocytochemical Localization of Angiotensinogen in Rat-Brain - Dependence of Neuronal Immunoreactivity On Method of Tissue Processing

Campbell, DJ, Sernia, C, Thomas, WG and Oldfield, BJ (1991). Immunocytochemical Localization of Angiotensinogen in Rat-Brain - Dependence of Neuronal Immunoreactivity On Method of Tissue Processing. Journal of Neuroendocrinology, 3 (6), 653-660. doi: 10.1111/j.1365-2826.1991.tb00330.x

THE IMMUNOCYTOCHEMICAL LOCALIZATION OF ANGIOTENSINOGEN IN THE RAT OVARY

THOMAS, WG and SERNIA, C (1990). THE IMMUNOCYTOCHEMICAL LOCALIZATION OF ANGIOTENSINOGEN IN THE RAT OVARY. Cell and Tissue Research, 261 (2), 367-373. doi: 10.1007/BF00318679

Angiotensin receptors in an Australian marsupial, the brushtail possum Trichosurus vulpecula

Sernia, C, Lello, P and Thomas, WG (1990). Angiotensin receptors in an Australian marsupial, the brushtail possum Trichosurus vulpecula. General and Comparative Endocrinology, 77 (1), 116-126. doi: 10.1016/0016-6480(90)90212-5

Immunocytochemical Localization of Angiotensinogen and Angiotensin-Ii in the Rat Pituitary

Thomas, WG and Sernia, C (1990). Immunocytochemical Localization of Angiotensinogen and Angiotensin-Ii in the Rat Pituitary. Journal of Neuroendocrinology, 2 (3), 297-304. doi: 10.1111/j.1365-2826.1990.tb00408.x

Uterine oxytocin receptors in an australian marsupial, the brushtail possum, Trichosurus vulpecula

Sernia, C, Garciaaragon, J, Thomas, WG and Gemmell, RT (1990). Uterine oxytocin receptors in an australian marsupial, the brushtail possum, Trichosurus vulpecula. Comparative Biochemistry and Physiology -- Part A: Physiology, 95 (1), 135-138. doi: 10.1016/0300-9629(90)90021-J

Oxytocin Receptors in the Ovine Corpus-Luteum

Sernia, C, Gemmell, RT and Thomas, WG (1989). Oxytocin Receptors in the Ovine Corpus-Luteum. Journal of Endocrinology, 121 (1), 117-123. doi: 10.1677/joe.0.1210117

Immunocytochemical localization of angiotensinogen in the rat brain

Thomas, WG and Sernia, C (1988). Immunocytochemical localization of angiotensinogen in the rat brain. Neuroscience, 25 (1), 319-341. doi: 10.1016/0306-4522(88)90029-2

Purification of Rat Angiotensinogen

Sernia, C, Davis, M and Thomas, WG (1986). Purification of Rat Angiotensinogen. Preparative Biochemistry, 16 (1), 45-59. doi: 10.1080/00327488608062458

Regulation of rat brain angiotensin II (AII) receptors by intravenous AII and low dietary Na+

Thomas, WG and Sernia, C (1985). Regulation of rat brain angiotensin II (AII) receptors by intravenous AII and low dietary Na+. Brain Research, 345 (1), 54-61. doi: 10.1016/0006-8993(85)90835-2

Liver Angiotensin-Ii Receptors in the Rat - Binding-Properties and Regulation by Dietary Na+ and Angiotensin-II

Sernia, C, Sinton, L, Thomas, WG and Pascoe, W (1985). Liver Angiotensin-Ii Receptors in the Rat - Binding-Properties and Regulation by Dietary Na+ and Angiotensin-II. Journal of Endocrinology, 106 (1), 103-111. doi: 10.1677/joe.0.1060103

Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors

Bloxham, Conor, Foster, Simon and Thomas, Walter (2020). Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors. 29th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Trieste, Italy, 11-14 September 2019. Oxford, United Kingdom: Oxford University Press.

Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts

Reichelt, M., Wang, Z., Thorn, C., Paravicini, T. and Thomas, W. G. (2019). Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts. ESC Congress / World Congress of Cardiology, Paris, France, 31 August - 4 September 2019. Oxford, United Kingdom: Oxford University Press.

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Hudson, J., Mills, R., Titmarsh, D., Koenig, X., Parker, B., Ryall, J., Quaife-Ryan, G., Voges, H., Hodson, M., Ferguson, C., Drowley, L., Plowright, A., Wang, Q., Gregorevic, P., Xin, M., Thomas, W., Parton, R., Nielsen, L., Launikonis, B., James, D., Elliott, D. and Porrello, E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Abstracts for the 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, Australia, 10 - 13 August 2017. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2017.06.375

Cellular transcriptomic analysis of multiple cardiac lineages during heart development and regeneration

Ryan, Quaife-G., Ma, Z., Sim, C., Ramialison, M., Thomas, W., Hudson, J. and Porrello, E. (2016). Cellular transcriptomic analysis of multiple cardiac lineages during heart development and regeneration. 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide, SA Australia, 4 – 7 August 2016. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2016.06.079

TAS2Rs-A new class of functional G protein-coupled receptors in heart.

Thomas, Walter (2016). TAS2Rs-A new class of functional G protein-coupled receptors in heart.. 25th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Istanbul Turkey, Sep 01-05, 2015. OXFORD: OXFORD UNIV PRESS.

Transcriptional Regulation of Taste Receptor Genes: Novel Insights From In Silico and Cardiac Gene Expression Analyses

Foster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, dos Remedios, Cris G., Thomas, Walter G. and Ramialison, Mirana (2015). Transcriptional Regulation of Taste Receptor Genes: Novel Insights From In Silico and Cardiac Gene Expression Analyses. 15th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS), Brisbane, QLD Australia, 03-05 December 2014. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/chemse/bjv008

The function of ErbB4 receptor in the postnatal mouse heart

Wang, Z., Chan, H. W., Thomas, W. G. and Paravicini, T. M. (2014). The function of ErbB4 receptor in the postnatal mouse heart. 35th Annual Scientific Meeting of the High Blood Pressure Research Council of Australia (HBPRCA) / 39th Annual Scientific Meeting of the Australian-Atherosclerosis-Society (AAS), Melbourne Australia, 05 - 07 December 2013. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1161/HYP.0000000000000010

Investigating the Role of Epidermal Growth Factor Receptors in Angiotensin II-induced Hypertrophic Signalling in Cardiomyocytes

Wang, Zhen, Chan, Hsiu-Wen, Chen, Chen, Thomas, Walter G. and Paravicini, Tamara M. (2013). Investigating the Role of Epidermal Growth Factor Receptors in Angiotensin II-induced Hypertrophic Signalling in Cardiomyocytes. American Heart Association High Blood Pressure Research Scientific Sessions, New Orleans La, 11-14 September 2013. Philadelphia, PA United States: Lippincott Williams and Wilkins.

Unravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approaches

George, Amee J., Hannan, Ross D. and Thomas, Walter G. (2013). Unravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approaches. The International Symposium ‘Ca2+ Signalling and Transport in Health and Disease’, Aarhus, Denmark, 19 - 20 June 2012. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing Ltd.. doi: 10.1111/febs.12509

A functional SiRNA screening approach to investigate the mechanism underlying GPCR-mediated EGFR Transactivation in Malignancy

George, A. J., Purdue, B. W., Gould, K., Handoko, Y., Thomas, D. W., Morgan, K. A., Simpson, K. J., Thomas, W. G. and Hannan, R. D. (2012). A functional SiRNA screening approach to investigate the mechanism underlying GPCR-mediated EGFR Transactivation in Malignancy. 22nd Biennial Congress of the European Association for Cancer Research, Barcelona Spain, 07-10 July 2012. Oxford, United Kingdom: Pergamon. doi: 10.1016/S0959-8049(12)71277-7

Beta-amino acid substitution of angiotensin III imparts significant AT2 receptor selectivity and vascular function

Jones, E. S., DelBorgo, M., Bosnjak, S., Perlmutter, P., Thomas, W. G., Aguilar, M. I. and Widdop, R. E. (2012). Beta-amino acid substitution of angiotensin III imparts significant AT2 receptor selectivity and vascular function. 33rd Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia (HBPRCA), Perth, WA, Australia, 6-9 December 2011. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1161/HYP.0b013e3182602164

Injection of rAAV-Orai1 in adult wt and dystrophic mice up-regulates store operated calcium entry

Cully, T. R., Purdue, B. W., Thomas, W. G., Gregorevic, P. and Launikonis, B. S. (2012). Injection of rAAV-Orai1 in adult wt and dystrophic mice up-regulates store operated calcium entry. Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy/French-Society-of-Cell-and-Gene-Therapy, Versailles, France, 25-29 October 2012. New Rochelle, NY, United States: Mary Ann Liebert.

Knockdown of Angiotensinogen Protein in Vivo

O'Callaghan, E. L., Thomas, W. G. and Allen, A. M. (2011). Knockdown of Angiotensinogen Protein in Vivo. 32nd Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, Melbourne Australia, Dec 01-03, 2010. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

SINGLE BETA-AMINO ACID SUBSTITUTIONS TO ANGIOTENSIN II CONFER AT2 RECEPTOR SELECTIVITY AND VASCULAR FUNCTION

Bosnyak, S., Jones, E. S., Kirsch, J. F., Del Borgo, M. P., Welungoda, I., Clayton, D., Hausler, N., Unabia, S., Perlmutter, P., Thomas, W. G., Aguilar, M-I and Widdop, R. E. (2011). SINGLE BETA-AMINO ACID SUBSTITUTIONS TO ANGIOTENSIN II CONFER AT2 RECEPTOR SELECTIVITY AND VASCULAR FUNCTION. 32nd Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, Melbourne Australia, Dec 01-03, 2010. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Role of angiotensin in the rostral ventrolateral medulla in the pressor response to aversive stress

Chen, Daian, Thu-Phuc Nguyen-Huu, Bassi, Jaspreet K., Davern, Pamela, Thomas, Walter G., Head, Geoff A. and Allen, Andrew M. (2011). Role of angiotensin in the rostral ventrolateral medulla in the pressor response to aversive stress. Experimental Biology Meeting 2011, Washington Dc, Apr 09-13, 2011. BETHESDA: FEDERATION AMER SOC EXP BIOL.

ANGIOTENSIN II INCREASES OSTEOBLAST RANKL:OPG RATIO THROUGH TRANSACTIVATION OF ERBB RECEPTORS BY EGF-LIKE LIGANDS

MacRae, K, Thomas, W and Sernia C (2011). ANGIOTENSIN II INCREASES OSTEOBLAST RANKL:OPG RATIO THROUGH TRANSACTIVATION OF ERBB RECEPTORS BY EGF-LIKE LIGANDS. European Congress on Osteoporosis and Osteoarthritis – ESCEO11, Valencia Spain, 23-26 March 2011.

Angiotensin II increases osteoblast RANKL:OPG ratio through transactivation of ErbB receptors by EGF-like ligands

MacRae, Kirsty, Thomas, Walter and Senia, Conrad (2011). Angiotensin II increases osteoblast RANKL:OPG ratio through transactivation of ErbB receptors by EGF-like ligands. 1st IOF-ESCEO Pre-Clinical Symposium, Valencia, SPAIN, 23-26, 2011.

Angiotensin II regulates RANKL:OPG ratio potentially through transactivation of ErbB receptors by EGF-like ligands

MacRae, K., Thomas, W. and Sernia C. (2011). Angiotensin II regulates RANKL:OPG ratio potentially through transactivation of ErbB receptors by EGF-like ligands. 2nd Asia-Pacific Osteoporosis and Bone Meeting, Gold Coast , QLD, Australia, 4th-8th September 2011. Springer.

UMR-106 osteoblast cells express components of the renin-angiotensin system and are regulated by glucocorticoids

Lei, C., MacRae, K., Thomas, W. and Sernia, C. (2011). UMR-106 osteoblast cells express components of the renin-angiotensin system and are regulated by glucocorticoids. 2nd Asia-Pacific Osteoporosis and Bone Meeting, Gold Coast , QLD Australia, 4th-8th September 2011.

Beta-amino acid substituted Angiotensin II peptidomimetics as AT2 receptor-selective ligands

Widdop, RE, Kirsch, J, Bosnyak, S, Unabia, S, Del Borgo, M, Perlmutter, P, Thomas, W, Aguilar, MI and Jones, ES (2010). Beta-amino acid substituted Angiotensin II peptidomimetics as AT2 receptor-selective ligands. Conference on High Blood Pressure Research, Washington, DC, U.S.A., 13-16 October 2010. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins. doi: 10.1161/HYP.0b013e3181faa059

REDUCED ANGIOTENSINOGEN GENE EXPRESSION FOLLOWING ANGIOTENSIN II STIMULATION OF ASTROCYTES EXPRESSING THE ANGIOTENSIN TYPE 1A RECEPTOR

O'Callaghan, EL, Thomas, WG and Allen, AM (2010). REDUCED ANGIOTENSINOGEN GENE EXPRESSION FOLLOWING ANGIOTENSIN II STIMULATION OF ASTROCYTES EXPRESSING THE ANGIOTENSIN TYPE 1A RECEPTOR. 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, Sydney AUSTRALIA, DEC 01-03, 2009.

Potential roles of a disintegrin and metalloprotease proteins 10, 12, and 17 in angiotensin II-mediated transactivation of epidermal growth factor receptors

Bourne, Allison M., Hannan, Ross D. and Thomas, WG (2009). Potential roles of a disintegrin and metalloprotease proteins 10, 12, and 17 in angiotensin II-mediated transactivation of epidermal growth factor receptors. Basic Cardiovascular Sciences Conference 2009, Henderson NV, 20-23 July 2009. United States: Lippincott Williams & Wilkins. doi: 10.1161/RES.0b013e3181bcaeff

Baroreceptor reflex stimulation does not induce cytomegalovirus promoter-driven transgene expression in the ventrolateral medulla in vivo

Allen, Andrew M., Dosanjh, Jaspreet, Dassanayake, Sashikala, Tan, Geraldine and Thomas, Walter G. (2006). Baroreceptor reflex stimulation does not induce cytomegalovirus promoter-driven transgene expression in the ventrolateral medulla in vivo. 4th Congress of the International Society for Autonomic Neuroscience, Marseille, France, July, 2005. Amsterdam: Elsevier B.V.. doi: 10.1016/j.autneu.2006.02.024

Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy

Chan, Hsiu-Wen, Jenkins, Anna, Pipolo, Luisa, Hannan, Ross D., Thomas, Walter G. and Smith, Nicola J. (2006). Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy. 10th Swiss Receptor Workshop: "From Research to Therapeutics", Basel, Switzerland, 12-15 March 2006. New York, NY, U.S.A.: Marcel Dekker. doi: 10.1080/10799890600923187

Urotensin II stimulates collagen synthesis by cardiac fibroblasts and hypertrophic signalling in cardiomyocytes via G(alpha)q- and Ras-dependent pathways

Tzanidis, A, Hannan, RD, Thomas, WG, Onan, D, See, F and Krum, H (2001). Urotensin II stimulates collagen synthesis by cardiac fibroblasts and hypertrophic signalling in cardiomyocytes via G(alpha)q- and Ras-dependent pathways. NEW YORK: ELSEVIER SCIENCE INC.

Angiotensin II receptor (AT(1A)) endocytosis involves phosphorylation of the carboxyl-terminus ''STL'' internalization motif.

Thomas, WG, Motel, TJ, Kule, CE and Baker, KM (1996). Angiotensin II receptor (AT(1A)) endocytosis involves phosphorylation of the carboxyl-terminus ''STL'' internalization motif.. DALLAS: AMER HEART ASSOC.

Cardiac effects of AII - AT(1A) receptor signaling, desensitization, and internalization

Thomas, WG, Thekkumkara, TJ and Baker, KM (1996). Cardiac effects of AII - AT(1A) receptor signaling, desensitization, and internalization. 1st International Symposium on the Cellular and Molecular Aspects of Angiotensin Receptors, Gainesville Fl, Dec 09-11, 1994. NEW YORK: PLENUM PRESS DIV PLENUM PUBLISHING CORP.

An Essential Role for Leu316 and Tyr319 in Angiotensin-Ii (Atia) Receptor Endocytosis

Thomas, WG, Baker, KM, Motel, TJ and Thekkumkara, TJ (1995). An Essential Role for Leu316 and Tyr319 in Angiotensin-Ii (Atia) Receptor Endocytosis. DALLAS: AMER HEART ASSOC.