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We have discovered a new way to alert the immune system to cancer cells and here wish to explore… Major research focus is on RNA interference (RNAi) based gene therapy and cancer therapy. Closely… Inhibition of cervical cancer cell growth in vitro and in vivo with dual shRNAs… Identifying therapeutic targets and developing targeted cancer therapies for cancer stem cells… Novel photodynamic therapy for targeted skin cancer treatment: an integrated bionanotechnology… Rational design and delivery of small RNAs for effective cancer gene therapies… working in the area of using RNAi to treat viral diseases and cancers. He also has a strong background in immunology and vaccine development.… in a cervical cancer model. However, using this vector to carry two copies of the same shRNA or two…
Dr. Wenyi Gu’s early education was conducted in China which include his undergraduate and master’s degrees in veterinary medicine. In 1996, he migrated to Australia and pursued his PhD study in biochemistry & molecular biology at the Australian National University (ANU). After a short period of …
Dr. Gu's research focus is on RNA interference (RNAi) based gene therapy and cancer therapy. Closely associated with this focus, he also interests in subjects such as oncogenes, cancer stem cells, targeted delivery, cancer cell biomarkers, and cancer immunotherapy. His recent research more focuses o …
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extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer… Hypoxia increases the exosome release from ovarian cancer cells and promotes the epithelial-mesenchymal transition of target cells… Extracellular vesicles and ovarian cancer… UniQuest-INOVIQ Umbrella Research and Option Agreement: Exosome based ovarian cancer screening… realistic that a clinically useful antenatal screening test can be developed. Unlike diseases such as cancer… Assays for clinically relevant complications (including ovarian cancers, and obstetrical syndromes… Pancreatic cancer is the fourth most common cause of death due to cancer in the world. It is known…
I am Professor, NHMRC Investigator Fellow (EL2) and group leader (Exosome Biology Laboratory) at UQ Centre for Clinical Research. I am nationally and internationally (>20 invitations to international meetings in the last 5 years) acknowledged key opinion leader on Extracellular Vesicle (rated 3th w …
My research program focused on obstetrics and gynaecology, and it has investigated the release of extracellular vesicles by the placenta during gestation, and tumour cells in ovarian cancer progression, and their utility as a biomarker for a wide range of pregnancy complications, and ovarian cancer. …
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SKIN REGENERATION AND RADIATION INDUCED CANCER… investigate partial different equation models that describe the distribution and spreading of cancer… during development, and in metastasizing cancer cells. We analyse the effects of varying cell density and…
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immunological defenses and cancer immunosurveillance. Current research: My current research focuses… The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy… Reversing tumour necrosis factor-mediated immunosuppression to boost immunity against experimental CD19+ blood cancers… Background: Despite advances in treatment and earlier detection, cancer is… NK cells are highly efficient at preventing cancer metastasis but are infrequently found in the…
In 2012, I achieved a significant milestone by becoming the first student to complete a doctoral degree from the prestigious International PhD Program at Institute Pasteur, Paris/France. This accomplishment not only set the trajectory of my academic pursuits but also underscored my dedication and pa …
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Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer… Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy… against the cancer cell lines MM96L, HeLa and BGC-823. The novel cyclotides reported here: (1…
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