The University of Queensland

Production of polyclonal antisera

Cooper, Helen M. and Paterson, Yvonne (2008). Production of polyclonal antisera. Current protocols in molecular biology. (pp. 11.12.1-11.12.10) edited by Frederick M. Ausubel, Roger Brent, Robert E. Kingston, David D. Moore, J. G. Seidman and Kevin Struhl. New York, U.S.: John Wiley. doi: 10.1002/0471142727.mb1112s81

RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling

Sempert, Kai, Shohayeb, Belal, Lanoue, Vanessa, O’Brien, Elizabeth A., Flores, Cecilia and Cooper, Helen M. (2023). RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling. Frontiers in Molecular Neuroscience, 16 ARTN 1253801, 1253801. doi: 10.3389/fnmol.2023.1253801

Embryonic stem cell-derived neurons as a model system for epigenome maturation during development

Martin, Sally, Poppe, Daniel, Olova, Nelly, O’Leary, Conor, Ivanova, Elena, Pflueger, Jahnvi, Dechka, Jennifer, Simmons, Rebecca K., Cooper, Helen M., Reik, Wolf, Lister, Ryan and Wolvetang, Ernst J. (2023). Embryonic stem cell-derived neurons as a model system for epigenome maturation during development. Genes, 14 (5) 957. doi: 10.3390/genes14050957

The ups and downs of Pax6 in neural stem cells

Shohayeb, Belal and Cooper, Helen M. (2023). The ups and downs of Pax6 in neural stem cells. Journal of Biological Chemistry, 299 (5) 104680, 104680. doi: 10.1016/j.jbc.2023.104680

Hydrocephalus in Nfix−/− mice is underpinned by changes in ependymal cell physiology

Harkins, Danyon, Harvey, Tracey J., Atterton, Cooper, Miller, Ingrid, Currey, Laura, Oishi, Sabrina, Kasherman, Maria, Davila, Raul Ayala, Harris, Lucy, Green, Kathryn, Piper, Hannah, Parton, Robert G., Thor, Stefan, Cooper, Helen M. and Piper, Michael (2022). Hydrocephalus in Nfix−/− mice is underpinned by changes in ependymal cell physiology. Cells, 11 (15) 2377, 2377. doi: 10.3390/cells11152377

Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice

Chau, Tevin CY., Baek, Sungmin, Coxam, Baptiste, Skoczylas, Renae, Rondon‐Galeano, Maria, Bower, Neil I., Wainwright, Elanor N., Stacker, Steven A., Cooper, Helen M., Koopman, Peter A., Lagendijk, Anne K., Harvey, Natasha L., François, Mathias and Hogan, Benjamin M. (2021). Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice. Developmental Dynamics, 251 (2) dvdy.390, 336-349. doi: 10.1002/dvdy.390

Conservation of neural progenitor identity and the emergence of neocortical neuronal diversity

Shohayeb, Belal, Muzar, Zukhrofi and Cooper, Helen M. (2021). Conservation of neural progenitor identity and the emergence of neocortical neuronal diversity. Seminars in Cell and Developmental Biology, 118, 4-13. doi: 10.1016/j.semcdb.2021.05.024

DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

Morcom, Laura, Gobius, Ilan, Marsh, Ashley P. L., Suárez, Rodrigo, Lim, Jonathan W. C., Bridges, Caitlin, Ye, Yunan, Fenlon, Laura R., Zagar, Yvrick, Douglass, Amelia M., Donahoo, Amber-Lee, Fothergill, Thomas, Shaikh, Samreen, Kozulin, Peter, Edwards, Timothy J., Cooper, Helen M., IRC5 Consortium, Sherr, Elliott H., Chédotal, Alain, Leventer, Richard J., Lockhart, Paul J. and Richards, Linda J. (2021). DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. eLife, 10 e61769, 1-35. doi: 10.7554/eLife.61769

Mosaic synapses in epilepsy

Shohayeb, Belal and Cooper, Helen M. (2021). Mosaic synapses in epilepsy. Science, 372 (6539), 235-236. doi: 10.1126/science.abh3555

Mechanisms of cortical development: From the embryo to adulthood

Cooper, Helen M. and Flores, Cecilia (2021). Mechanisms of cortical development: From the embryo to adulthood. Seminars in Cell and Developmental Biology, 118, 1-3. doi: 10.1016/j.semcdb.2021.08.012

The role of lipids in ependymal development and the modulation of adult neural stem cell function during aging and disease

Harkins, Danyon, Cooper, Helen M. and Piper, Michael (2020). The role of lipids in ependymal development and the modulation of adult neural stem cell function during aging and disease. Seminars in Cell and Developmental Biology, 112, 61-68. doi: 10.1016/j.semcdb.2020.07.018

Dopamine axon targeting in the nucleus accumbens in adolescence requires netrin-1

Cuesta, Santiago, Nouel, Dominique, Reynolds, Lauren M., Morgunova, Alice, Torres-Berrío, Angélica, White, Amanda, Hernandez, Giovanni, Cooper, Helen M. and Flores, Cecilia (2020). Dopamine axon targeting in the nucleus accumbens in adolescence requires netrin-1. Frontiers in Cell and Developmental Biology, 8 487, 487. doi: 10.3389/fcell.2020.00487

Draxin-mediated regulation of granule cell progenitor differentiation in the postnatal hippocampal dentate gyrus

Tawarayama, Hiroshi, Yamada, Hirohisa, Amin, Ruhul, Morita-Fujimura, Yuiko, Cooper, Helen M, Shinmyo, Yohei, Tanaka, Hideaki and Ikawa, Shuntaro (2020). Draxin-mediated regulation of granule cell progenitor differentiation in the postnatal hippocampal dentate gyrus. Neuroscience, 431, 184-192. doi: 10.1016/j.neuroscience.2020.02.005

Adherens junctions: guardians of cortical development

Veeraval, Lenin, O’Leary, Conor J. and Cooper, Helen M. (2020). Adherens junctions: guardians of cortical development. Frontiers in Cell and Developmental Biology, 8 6, 6. doi: 10.3389/fcell.2020.00006

WNT5a regulates epithelial morphogenesis in the developing choroid plexus

Langford, Michael B., O'Leary, Conor J., Veeraval, Lenin, White, Amanda, Lanoue, Vanessa and Cooper, Helen M. (2020). WNT5a regulates epithelial morphogenesis in the developing choroid plexus. Cerebral Cortex, 30 (6), 3617-3631. doi: 10.1093/cercor/bhz330

Loss of Neogenin1 in human colorectal carcinoma cells causes a partial EMT and wound-healing response

Chaturvedi, Vishal, Fournier-Level, Alexandre, Cooper, Helen M. and Murray, Michael J. (2019). Loss of Neogenin1 in human colorectal carcinoma cells causes a partial EMT and wound-healing response. Scientific Reports, 9 (1) 4110, 4110. doi: 10.1038/s41598-019-40886-y

Branching mechanisms shaping dendrite architecture

Lanoue, Vanessa and Cooper, Helen M. (2019). Branching mechanisms shaping dendrite architecture. Developmental Biology, 451 (1), 16-24. doi: 10.1016/j.ydbio.2018.12.005

Brain targeting delivery facilitated by ligand-functionalized layered double hydroxide nanoparticles

Chen, Weiyu, Zuo, Huali, Zhang, Enqi, Li, Li, Henrich-Noack, Petra, Cooper, Helen M., Qian, Yujin and Xu, Zhi Ping (2018). Brain targeting delivery facilitated by ligand-functionalized layered double hydroxide nanoparticles. ACS Applied Materials and Interfaces, 10 (24) acsami.8b04613, 20326-20333. doi: 10.1021/acsami.8b04613

Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis

Tawarayama, Hiroshi, Yamada, Hirohisa, Amin, Ruhul, Morita-Fujimura, Yuiko, Cooper, Helen M., Shinmyo, Yohei, Kawata, Masakado, Ikawa, Shuntaro and Tanaka, Hideaki (2018). Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Scientific Reports, 8 (1) 840, 1-10. doi: 10.1038/s41598-018-19346-6

DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome

Marsh, Ashley P. L., Edwards, Timothy J., Galea, Charles, Cooper, Helen M., Engle, Elizabeth C., Jamuar, Saumya S., Méneret, Aurélie, Moutard, Marie-Laure, Nava, Caroline, Rastetter, Agnès, Robinson, Gail, Rouleau, Guy, Roze, Emmanuel, Smith, Megan, Trouillard, Oriane, Billette de Villemeur, Thierry, Walsh, Christopher A., Yu, Timothy W., IRC5 Consortium, Heron, Delphine, Sherr, Elliott H., Richards, Linda J., Depienne, Christel, Leventer, Richard J. and Lockhart, Paul J. (2017). DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome. Human Mutation, 39 (1), 23-39. doi: 10.1002/humu.23361

MnAl layered double hydroxide nanoparticles as a dual-functional platform for magnetic resonance imaging and siRNA delivery

Zuo, Huali, Chen, Weiyu, Li, Bei, Xu, Kewei, Cooper, Helen, Gu, Zi and Xu, Zhi Ping (2017). MnAl layered double hydroxide nanoparticles as a dual-functional platform for magnetic resonance imaging and siRNA delivery. Chemistry - A European Journal, 23 (57), 14299-14306. doi: 10.1002/chem.201702835

The Wnt receptor Ryk is a negative regulator of mammalian dendrite morphogenesis

Lanoue, Vanessa, Langford, Michael, White, Amanda, Sempert, Kai, Fogg, Lily and Cooper, Helen M. (2017). The Wnt receptor Ryk is a negative regulator of mammalian dendrite morphogenesis. Scientific Reports, 7 (1) 5965, 5965.1-5965.11. doi: 10.1038/s41598-017-06140-z

Neogenin recruitment of the WAVE regulatory complex to ependymal and radial progenitor adherens junctions prevents hydrocephalus

O'Leary, Conor J., Nourse, Cathrin C., Lee, Natalie K., White, Amanda, Langford, Michael, Sempert, Kai, Cole, Stacey J. and Cooper, Helen M. (2017). Neogenin recruitment of the WAVE regulatory complex to ependymal and radial progenitor adherens junctions prevents hydrocephalus. Cell Reports, 20 (2), 370-383. doi: 10.1016/j.celrep.2017.06.051

A facile way of modifying layered double hydroxide nanoparticles with targeting ligand-conjugated albumin for enhanced delivery to brain tumour cells

Zuo, Huali, Chen, Weiyu, Cooper, Helen M. and Xu, Zhi Ping (2017). A facile way of modifying layered double hydroxide nanoparticles with targeting ligand-conjugated albumin for enhanced delivery to brain tumour cells. ACS Applied Materials & Interfaces, 9 (24), 20444-20453. doi: 10.1021/acsami.7b06421

DCC confers susceptibility to depression-like behaviors in humans and mice and is regulated by miR-218

Torres-Berrío, Angélica, Lopez, Juan Pablo, Bagot, Rosemary C., Nouel, Dominique, Dal Bo, Gregory, Cuesta, Santiago, Zhu, Lei, Manitt, Colleen, Eng, Conrad, Cooper, Helen M., Storch, Kai-Florian, Turecki, Gustavo, Nestler, Eric J. and Flores, Cecilia (2017). DCC confers susceptibility to depression-like behaviors in humans and mice and is regulated by miR-218. Biological Psychiatry, 81 (4), 306-315. doi: 10.1016/j.biopsych.2016.08.017

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

Lee, Natalie K., Fok, Ka Wai, White, Amanda, Wilson, Nicole H., O’Leary, Conor J., Cox, Hayley L., Michael, Magdalene, Yap, Alpha S. and Cooper, Helen M. (2016). Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nature Communications, 7 (11082) 11082, 11082. doi: 10.1038/ncomms11082

Validating Eaton's hypothesis: cubane as a benzene bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675

Crosslinking to enhance colloidal stability and redispersity of layered double hydroxide nanoparticles

Zuo, Huali, Gu, Zi, Cooper, Helen and Xu, Zhi Ping (2015). Crosslinking to enhance colloidal stability and redispersity of layered double hydroxide nanoparticles. Journal of Colloid and Interface Science, 459, 10-16. doi: 10.1016/j.jcis.2015.07.063

The Netrin/RGM receptor, neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit

O'Leary, Conor J., Bradford, DanaKai, Chen, Min, White, Amanda, Blackmore, Daniel G. and Cooper, Helen M. (2014). The Netrin/RGM receptor, neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit. Stem Cells, 33 (2), 503-514. doi: 10.1002/stem.1861

Engineering small MgAl-layered double hydroxide nanoparticles for enhanced gene delivery

Dong, Haiyan, Chen, Min, Rahman, Shafiur, Parekh, Harendra S., Cooper, Helen M. and Xu, Zhi Ping (2014). Engineering small MgAl-layered double hydroxide nanoparticles for enhanced gene delivery. Applied Clay Science, 100 (C), 66-75. doi: 10.1016/j.clay.2014.04.028

Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases

Chen, Xiang-Jun, Xu, Huan, Cooper, Helen M. and Liu, Yaobo (2014). Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases. Science China Life Sciences, 57 (4), 372-377. doi: 10.1007/s11427-014-4639-9

The Yin and Yang of Wnt/Ryk axon guidance in development and regeneration

Clark, Charlotte E. J., Liu, Yaobo and Cooper, Helen M. (2014). The Yin and Yang of Wnt/Ryk axon guidance in development and regeneration. Science China Life Sciences, 57 (4), 366-371. doi: 10.1007/s11427-014-4640-3

Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth

Clark, Charlotte E. J., Richards, , Linda J., Stacker, Steven A. and Cooper, Helen M. (2014). Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth. Growth Factors, 32 (1), 11-17. doi: 10.3109/08977194.2013.875544

Dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients

Manitt C., Eng C., Pokinko M., Ryan R.T., Torres-Berrio A., Lopez J.P., Yogendran S.V., Daubaras M.J.J., Grant A., Schmidt E.R.E., Tronche F., Krimpenfort P., Cooper H.M., Pasterkamp R.J., Kolb B., Turecki G., Wong T.P., Nestler E.J., Giros B. and Flores C. (2013). Dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Translational Psychiatry, 3 (12) e105, e338-e338. doi: 10.1038/tp.2013.105

Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine

Kim, Jee Hyun, Lavan, Doron, Chen, Nicola, Flores, Cecilia, Cooper, Helen and Lawrence, Andrew J. (2013). Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine. Psychopharmacology, 230 (4), 607-616. doi: 10.1007/s00213-013-3187-5

RGMa regulates cortical interneuron migration and differentiation

O'Leary, Conor, Cole, Stacey J., Langford, Michael, Hewage, Jayani, White, Amanda and Cooper, Helen M. (2013). RGMa regulates cortical interneuron migration and differentiation. PLoS One, 8 (11) e81711, e81711.1-e81711.12. doi: 10.1371/journal.pone.0081711

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease

Reyes, Stefanie, Fu, Yuhong, Double, Kay L., Cottam, Veronica, Thompson, Lachlan H., Kirik, Deniz, Paxinos, George, Watson, Charles, Cooper, Helen M. and Halliday, Glenda M. (2013). Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease. Neurobiology of Aging, 34 (3), 873-886. doi: 10.1016/j.neurobiolaging.2012.07.019

Netrin-1 is required for efficient neural tube closure

Kee, Nigel, Wilson, Nicole, Key, Brian and Cooper, Helen (2013). Netrin-1 is required for efficient neural tube closure. Developmental Neurobiology, 73 (2), 176-187. doi: 10.1002/dneu.22051

One-pot preparation of highly fluorescent cadmium telluride/cadmium sulfide quantum dots under neutral-pH condition for biological applications

Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen, Lu, Gao Qing (Max) and Xu, Zhi Ping (2013). One-pot preparation of highly fluorescent cadmium telluride/cadmium sulfide quantum dots under neutral-pH condition for biological applications. Journal of Colloid and Interface Science, 390 (1), 3-10. doi: 10.1016/j.jcis.2012.08.003

Reduction in the size of layered double hydroxide nanoparticles enhances the efficiency of siRNA delivery

Chen, Min, Helen Cooper, Zhou, Ji Zhi, Bartlett, Perry F. and Xu, Zhi Ping (2013). Reduction in the size of layered double hydroxide nanoparticles enhances the efficiency of siRNA delivery. Journal of Colloid and Interface Science, 390 (1), 275-281. doi: 10.1016/j.jcis.2012.09.033

Tuning core-shell SiO2@CdTe@SiO2 fluorescent nanoparticles for cell labeling

Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen M. and Xu, Zhi Ping (2013). Tuning core-shell SiO2@CdTe@SiO2 fluorescent nanoparticles for cell labeling. Journal of Materials Chemistry B, 1 (17), 2315-2323. doi: 10.1039/c3tb20202j

Multiple Slits regulate the development of midline glial populations and the corpus callosum

Unni, Divya K., Piper, Michael, Moldrich, Randal X., Gobius, Ilan, Liu, Sha, Fothergill, Thomas, Donahoo, Amber-Lee S., Baisden, John M., Cooper, Helen M. and Richards, Linda J. (2012). Multiple Slits regulate the development of midline glial populations and the corpus callosum. Developmental Biology, 365 (1), 36-49. doi: 10.1016/j.ydbio.2012.02.004

The tangled web of non-canonical Wnt signalling in neural migration

Clark, Charlotte E.J., Nourse, C. Cathrin and Cooper, Helen M. (2012). The tangled web of non-canonical Wnt signalling in neural migration. Neurosignals, 20 (3), 202-220. doi: 10.1159/000332153

Altered development of Xenopus embryos in a hypogeomagnetic field

Mo, Wei-chuan, Liu, Ying, Cooper, Helen M. and He, Rong-qiao (2012). Altered development of Xenopus embryos in a hypogeomagnetic field. Bioelectromagnetics, 33 (3), 238-246. doi: 10.1002/bem.20699

Efficiency of layered double hydroxide nanoparticle-mediated delivery of siRNA is determined by nucleotide sequence

Wong, Yunyi, Cooper, Helen M., Zhang, Kai, Chen, Min, Bartlett, Perry and Xu, Zhi Ping (2012). Efficiency of layered double hydroxide nanoparticle-mediated delivery of siRNA is determined by nucleotide sequence. Journal of Colloid and Interface Science, 369 (1), 453-459. doi: 10.1016/j.jcis.2011.12.046

Synthesis of robust sandwich-like SiO2@CdTe@SiO2 fluorescent nanoparticles for cellular imaging

Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen M., Lu, Gao Qing (Max) and Xu, Zhi Ping (2012). Synthesis of robust sandwich-like SiO2@CdTe@SiO2 fluorescent nanoparticles for cellular imaging. Chemistry of Materials, 24 (3), 421-423. doi: 10.1021/cm2033417

Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice

Chawengsaksophak, Kallayanee, Svingen, Terje, Ng, Ee Ting, Epp, Trevor, Spiller, Cassy M., Clark, Charlotte, Cooper, Helen and Koopman, Peter (2012). Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice. Biology of Reproduction, 86 (1) 4, 1-12. doi: 10.1095/biolreprod.111.095232

Oncostatin M regulates neural precursor activity in the adult brain

Beatus, Paul, Jhaveri, Dhanisha J., Walker, Tara L., Lucas, Peter G., Rietze, Rodney L., Cooper, Helen M., Morikawa, Yoshihiro and Bartlett, Perry F. (2011). Oncostatin M regulates neural precursor activity in the adult brain. Developmental Neurobiology, 71 (7), 619-633. doi: 10.1002/dneu.20871

The netrin receptor DCC is required in the pubertal organization of mesocortical dopamine circuitry

Manitt, Colleen, Mimee, Andrea, Eng, Conrad, Pokinko, Matthew, Stroh, Thomas, Cooper, Helen M., Kolb, Bryan and Flores, Cecilia (2011). The netrin receptor DCC is required in the pubertal organization of mesocortical dopamine circuitry. The Journal of Neuroscience, 31 (23), 8381-8394. doi: 10.1523/JNEUROSCI.0606-11.2011

Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors

Dave, Richa K., Ellis, Tammy, Toumpas, Melissa C., Robson, Jonathan P., Julian, Elaine, Adolphe, Christelle, Bartlett, Perry F., Cooper, Helen M., Reynolds, Brent A. and Wainwright, Brandon J. (2011). Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors. PLoS One, 6 (2) e14680, e14680-1-e14680-13. doi: 10.1371/journal.pone.0014680

Efficient delivery of siRNA to cortical neurons using layered double hydroxide nanoparticles

Wong, Yunyi, Markham, Kathryn, Xu, Zhi Ping, Chen, Min, Liu, Gao Qing (Max), Bartlett, Perry F. and Cooper, Helen M. (2010). Efficient delivery of siRNA to cortical neurons using layered double hydroxide nanoparticles. Biomaterials, 31 (33), 8770-8779. doi: 10.1016/j.biomaterials.2010.07.077

Characterization of the netrin/RGMa receptor neogenin in neurogenic regions of the mouse and human adult forebrain

Bradford, D., Faull, R. L. M., Curtis, M. A. and Cooper, H. M. (2010). Characterization of the netrin/RGMa receptor neogenin in neurogenic regions of the mouse and human adult forebrain. Journal of Comparative Neurology, 518 (16), 3237-3253. doi: 10.1002/cne.22397

Synthetic neovibsanes and their ability to induce neuronal differentiation in PC12 cells

Chen, Apj, Muller, CC, Cooper, HM and Williams, CM (2010). Synthetic neovibsanes and their ability to induce neuronal differentiation in PC12 cells. Tetrahedron, 66 (34), 6842-6850. doi: 10.1016/j.tet.2010.06.056

Total synthesis of (+/-)-4,5-Bis-epi-neovibsanin A and B: A neurite outgrowth comparison study

Chen, Annette P. -J., Müller, C. Catharina, Cooper, Helen M. and Williams, Craig M. (2009). Total synthesis of (+/-)-4,5-Bis-epi-neovibsanin A and B: A neurite outgrowth comparison study. Organic Letters, 11 (16), 3758-3761. doi: 10.1021/ol901406j

Netrin-1: Diversity in development

Bradford, Dana, Cole, Stacey and Cooper, Helen M. (2009). Netrin-1: Diversity in development. International Journal of Biochemistry & Cell Biology, 41 (3), 487-493. doi: 10.1016/j.biocel.2008.03.014

Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity

Kee, Nigel, Wilson, Nicole, De Vries, Melissa, Bradford, DanaKai, Key, Brian and Cooper, Helen M. (2008). Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity. The Journal of Neuroscience, 28 (48), 12643-12653. doi: 10.1523/JNEUROSCI.4265-08.2008

Subcellular compartment targeting of layered double hydroxide nanoparticles

Xu, Zhi Ping, Niebert, Marcus, Porazik, Katharina, Walker, Tara L., Cooper, Helen M., Middelberg, Anton P.J., Gray, Peter P., Bartlett, Perry F. and Lu, Gao Qing (Max) (2008). Subcellular compartment targeting of layered double hydroxide nanoparticles. Journal of Controlled Release, 130 (1), 86-94. doi: 10.1016/j.jconrel.2008.05.021

Emerging roles for neogenin and its ligands in CNS development

de Vries, Melissa and Cooper, Helen M. (2008). Emerging roles for neogenin and its ligands in CNS development. Journal Of Neurochemistry, 106 (4), 1483-1492. doi: 10.1111/j.1471-4159.2008.05485.x

Production of polyclonal antisera

Cooper, Helen M and Paterson, Yvonne (2008). Production of polyclonal antisera. Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.], Appendix 3 (SUPPL. 43). doi: 10.1002/0471142956.cya03is43

Production of polyclonal antisera

Cooper, Helen M and Paterson, Yvonne (2008). Production of polyclonal antisera. Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], Chapter 11

Neogenin is expressed on neurogenic and gliogenic progenitors in the embryonic and adult central nervous system

Fitzgerald, D. P., Bradford, D. and Cooper, H. M. (2007). Neogenin is expressed on neurogenic and gliogenic progenitors in the embryonic and adult central nervous system. Gene Expression Patterns, 7 (7), 784-792. doi: 10.1016/j.modgep.2007.05.004

Layered double hydroxide nanoparticles as cellular delivery vectors of supercoiled plasmid DNA

Xu, Zhi Ping, Walker, Tara L., Liu, Kerh-lin, Cooper, Helen M., Lu, G. Q. Max and Bartlett, Perry F. (2007). Layered double hydroxide nanoparticles as cellular delivery vectors of supercoiled plasmid DNA. International Journal of Nanomedicine, 2 (2), 163-174. doi: 10.2147/IJN.S

Layered double hydroxide nanoparticles as cellular delivery vectors of supercoiled plasmid DNA

Xu, Zhi Ping, Walker, Tara L., Liu, Kerh-lin, Cooper, Helen M., Lu, G. Q. Max and Bartlett, Perry F. (2007). Layered double hydroxide nanoparticles as cellular delivery vectors of supercoiled plasmid DNA. International Journal of Nanomedicine, 2 (2), 163-74.

Neogenin: A multi-functional receptor regulating diverse developmental processes

Cole, S. J., Bradford, D. and Cooper, H. M. (2007). Neogenin: A multi-functional receptor regulating diverse developmental processes. The International Journal of Biochemistry & Cell Biology, 39 (9), 1569-1575. doi: 10.1016/j.biocel.2006.11.009

Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain

Fitzgerald, D. P., Cole, S. J., Hammond, A., Seaman, C. and Cooper, H. M. (2006). Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain. Neuroscience, 142 (3), 703-716. doi: 10.1016/j.neuroscience.2006.06.041

Localization of neogenin protein during morphogenesis in the mouse embryo

Fitzgerald, D. P., Seaman, C. and Cooper, H. M. (2006). Localization of neogenin protein during morphogenesis in the mouse embryo. Developmental Dynamics, 235 (6), 1720-1725. doi: 10.1002/dvdy.20744

Ryk: A novel Wnt receptor regulating axon pathfinding

Keeble, T. R. and Cooper, H. M. (2006). Ryk: A novel Wnt receptor regulating axon pathfinding. International Journal of Biochemistry & Cell Biology, 38 (12), 2011-2017. doi: 10.1016/j.biocel.2006.07.005

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination

Emery, B., Cate, H. S., Marriottt, M., Merson, T., Binder, M. D., Snell, C., Soo, P. Y., Murray, S., Croker, B., Zhang, J. G., Alexander, W. S., Cooper, H., Butzkueven, H. and Kilpatrick, T. J. (2006). Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination. Proceedings of The National Academy of Sciences of The United States of America, 103 (20), 7859-7864. doi: 10.1073/pnas.0602574103

The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum

Keeble, T. R., Halford, M., Seaman, C., Kee, N., Macheda, M., Andersen, R. B., Stacker, S. A. and Cooper, H. M. (2006). The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. Journal of Neuroscience, 26 (21), 5840-5848. doi: 10.1523/JNEUROSCI.1175-06.2006

Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents

Osborne, P. B., Halliday, G. M., Cooper, H. M. and Keast, J. R. (2005). Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience, 131 (3), 671-681. doi: 10.1016/j.neuroscience.2004.11.043

The Netrin receptor Neogenin is required for neural tube formation and somitogenesis in zebrafish

Mawdsley, David J., Cooper, Helen M., Hogan, Benjamin M., Cody, Stephen H., Lieschke, Graham J. and Heath, Joan K. (2004). The Netrin receptor Neogenin is required for neural tube formation and somitogenesis in zebrafish. Developmental Biology, 269 (1), 302-315. doi: 10.1016/j.ydbio.2004.02.001

Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor

Petratos, S., Butzkueven, H., Shipham, K., Cooper, H., Bucci, T., Reid, K., Lopes, E., Emery, B., Cheema, S. S. and Kilpatrick, T. J. (2003). Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor. Journal of Neuropathology And Experimental Neurology, 62 (4), 398-411.

Axon guidance receptors direct growth cone pathfinding: rivalry at the leading edge

Cooper, H. M. (2002). Axon guidance receptors direct growth cone pathfinding: rivalry at the leading edge. International Journal of Developmental Biology, 46 (4), 621-631.

Localization of the netrin guidance receptor, DCC, in the developing peripheral and enteric nervous systems

Seaman, Clare, Anderson, Richard, Emery, Ben and Cooper, Helen M. (2001). Localization of the netrin guidance receptor, DCC, in the developing peripheral and enteric nervous systems. Mechanisms of Development, 103 (1-2), 173-175. doi: 10.1016/S0925-4773(01)00350-1

Netrin-3 protein is localized to the axons of motor, sensory, and sympathetic neurons

Seaman, Clare and Cooper, Helen M. (2001). Netrin-3 protein is localized to the axons of motor, sensory, and sympathetic neurons. Mechanisms of Development, 101 (1-2), 245-248. doi: 10.1016/S0925-4773(00)00563-3

A zebrafish homologue of deleted in colorectal cancer (zdcc) is expressed in the first neuronal clusters of the developing brain

Hjorth, J. T., Gad, J., Cooper, H. and Key, B. (2001). A zebrafish homologue of deleted in colorectal cancer (zdcc) is expressed in the first neuronal clusters of the developing brain. Mechanisms of Development, 109 (1), 105-109. doi: 10.1016/S0925-4773(01)00513-5

The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina

Gad, Jacqueline M. , Keeling, Sharon L. , Shu, Tianzhi , Richards, Linda J. and Cooper, Helen M. (2000). The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Experimental Eye Research, 70 (6), 711-722. doi: 10.1006/exer.2000.0823

DCC plays a role in navigation of forebrain axons across the ventral midbrain commissure in embryonic Xenopus

Anderson, R. B., Cooper, H. M., Jackson, S. C., Seaman, C. and Key, B. (2000). DCC plays a role in navigation of forebrain axons across the ventral midbrain commissure in embryonic Xenopus. Developmental Biology, 217 (2), 244-253. doi: 10.1006/dbio.1999.9549

Expression of the netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain

Shu, Tianzhi, Valentino, Kimberly M., Seaman, Clare, Cooper, Helen M. and Richards, Linda J. (2000). Expression of the netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain. Journal of Comparative Neurology, 416 (2), 201-212. doi: 10.1002/(SICI)1096-9861(20000110)416:2<201::AID-CNE6>3.0.CO;2-Z

The deleted in colorectal cancer netrin guidance system: a molecular strategy for neuronal navigation

Cooper, Helen M. (1999). The deleted in colorectal cancer netrin guidance system: a molecular strategy for neuronal navigation. Clinical and Experimental Pharmacology and Physiology, 26 (9), 749-751. doi: 10.1046/j.1440-1681.1999.03106.x

The expression patterns of guidance receptors, DCC and neogenin, are spatially and temporally distinct throughout mouse embryogenesis

Gad, J. M., Keeling, S. L., Wilks, A. F., Tan, S. S. and Cooper, H. M. (1997). The expression patterns of guidance receptors, DCC and neogenin, are spatially and temporally distinct throughout mouse embryogenesis. Developmental Biology, 192 (2), 258-273. doi: 10.1006/dbio.1997.8756

Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis

Keeling, S. L., Gad, J. M. and Cooper, H. M. (1997). Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis. Oncogene, 15 (6), 691-700. doi: 10.1038/sj.onc.1201225

Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo

Cooper, H. M., Armes, P., Britto, J., Gad, J. and Wilks, A. F. (1995). Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo. Oncogene, 11 (11), 2243-2254.

Cell type-specific integrin variants with alternative α chain cytoplasmic domains

Tamura, R. N., Cooper, H. M., Collo, G. and Quaranta, V. (1991). Cell type-specific integrin variants with alternative α chain cytoplasmic domains. Proceedings of the National Academy of Sciences, 88 (22), 10183-10187. doi: 10.1073/pnas.88.22.10183

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin

Cooper, H. M., Tamura, R. N. and Quaranta, V. (1991). The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin. Journal of Cell Biology, 115 (3), 843-850. doi: 10.1083/jcb.115.3.843

Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta

Korhonen, M., Ylänne, J., Laitinen, L., Cooper, H. M., Quaranta, V. and Virtanen, I. (1991). Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta. Laboratory Investigation, 65 (3), 347-356.

A function for the integrin α6β4 in the hemidesmosome

Jones, Jonathan, C. R., Kurpakus, Michelle A., Cooper, Helen M. and Quaranta, Vito (1991). A function for the integrin α6β4 in the hemidesmosome. Cell Regulation, 2 (6), 427-438. doi: 10.1091/mbc.2.6.427

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4

Tamura, R. N., Rozzo, C., Starr, L., Chambers, J., Reichardt, L. F., Cooper, H. M. and Quaranta, V. (1990). Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4. Journal of Cell Biology, 111 (4), 1593-1604. doi: 10.1083/jcb.111.4.1593

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

Cheresh, David A., Smith, Jeffrey W., Cooper, Helen M. and Quaranta, Vito (1989). A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells. Cell, 57 (1), 59-69. doi: 10.1016/0092-8674(89)90172-4

The autoantigenic response to rabbit cytochrome C

Cooper, Helen M., Klinman, Norman R. and Paterson, Yvonne (1989). The autoantigenic response to rabbit cytochrome C. European Journal of Immunology, 19 (2), 315-322. doi: 10.1002/eji.1830190215

The heme moiety of cytochrome c is an autoreactive Ir gene-restricted T cell epitope

Cooper, H. M., Corradin, G. and Paterson, Y. (1988). The heme moiety of cytochrome c is an autoreactive Ir gene-restricted T cell epitope. Journal of Experimental Medicine, 168 (3), 1127-1143. doi: 10.1084/jem.168.3.1127

Site-directed Chemical Modification of Horse Cytochrome c Results in Changes in Antigenicity Due to Local and Long-range Conformational Perturbation

Cooper, Helen M., Jemmerson, Ronald, Hunt, Donald F., Griffin, Patrick R., Yates, John R. , Shabanowitz, Jeffrey, Zhu, Nian-Zhou and Paterson, Yvonne (1987). Site-directed Chemical Modification of Horse Cytochrome c Results in Changes in Antigenicity Due to Local and Long-range Conformational Perturbation. Journal of Biological Chemistry, 262 (24), 11591-11597.

Antibody response to the C-terminal peptide sequence in beef myoglobin

Cooper, H.M., Todd, P.E.E. and Leach, S.J. (1986). Antibody response to the C-terminal peptide sequence in beef myoglobin. Molecular Immunology, 23 (12), 1289-1299. doi: 10.1016/0161-5890(86)90014-3

Original antigenic sin and the production of autoantibodies

Cooper, H.M., Todd, P.E.E. and Leach, S.J. (1985). Original antigenic sin and the production of autoantibodies. Molecular Immunology, 22 (8), 921-927. doi: 10.1016/0161-5890(85)90078-1

Antibody response to myoglobins: effect of host species

Cooper, H.M., East, I.J., Todd, P.E.E. and Leach, S.J. (1984). Antibody response to myoglobins: effect of host species. Molecular Immunology, 21 (6), 479-487. doi: 10.1016/0161-5890(84)90063-4

Production of polyclonal antisera

Cooper, Helen M. and Paterson, Yvonne (2008). Production of polyclonal antisera.

Production of polyclonal antisera

Cooper, Helen M. and Paterson, Yvonne (2008). Production of polyclonal antisera.