The University of Queensland

Innate immunity in ALS

Lee, John D., Lee, Jia Y., Taylor, Stephen M., Noakes, Peter G. and Woodruff, Trent M. (2012). Innate immunity in ALS. Amyotrophic lateral sclerosis. (pp. 393-412) edited by Martin H. Maurer. Croatia: InTech - Open Access Publisher. doi: 10.5772/30341

Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease

Noakes, Peter G., Phillips, William D., Jeffree, Rosalind L., Steyn, Frederik J., Wolvetang, Ernst J., Henderson, Rob D., McCombe, Pamela A. and Ngo, Shyuan T. (2023). Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease. Journal of Experimental Neurology, 4 (1), 1-5. doi: 10.33696/neurol.4.067

The anaesthetics isoflurane and xenon reverse the synaptotoxic effects of Aβ1–42 on Megf10-dependent astrocytic synapse elimination and spine density in ex vivo hippocampal brain slices

Shi, Dai, Wong, Jaime K. Y., Zhu, Kaichuan, Noakes, Peter G. and Rammes, Gerhard (2023). The anaesthetics isoflurane and xenon reverse the synaptotoxic effects of Aβ1–42 on Megf10-dependent astrocytic synapse elimination and spine density in ex vivo hippocampal brain slices. International Journal of Molecular Sciences, 24 (2) 912, 1-20. doi: 10.3390/ijms24020912

Author Correction: Tick holocyclotoxins trigger host paralysis by presynaptic inhibition

Chand, Kirat K., Lee, Kah Meng, Lavidis, Nickolas A., Rodriguez-Valle, Manuel, Ijaz, Hina, Koehbach, Johannes, Clark, Richard J., Lew-Tabor, Ala and Noakes, Peter G. (2022). Author Correction: Tick holocyclotoxins trigger host paralysis by presynaptic inhibition. Scientific Reports, 12 (1) 20636, 1-1. doi: 10.1038/s41598-022-24528-4

Investigating the role of GABA in neural development and disease using mice lacking GAD67 or VGAT genes

Bolneo, Erika, Chau, Pak Yan S., Noakes, Peter G. and Bellingham, Mark C. (2022). Investigating the role of GABA in neural development and disease using mice lacking GAD67 or VGAT genes. International Journal of Molecular Sciences, 23 (14) 7965, 1-18. doi: 10.3390/ijms23147965

Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5

Hematopoietic prostaglandin D synthase inhibitor PK007 decreases muscle necrosis in DMD mdx model mice

Yarlagadda, Sai, Kulis, Christina, Noakes, Peter G. and Smythe, Mark L. (2021). Hematopoietic prostaglandin D synthase inhibitor PK007 decreases muscle necrosis in DMD mdx model mice. Life, 11 (9) 994, 994. doi: 10.3390/life11090994

Size-dependent dendritic maladaptations of hypoglossal motor neurons in SOD1G93A mice

Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2021). Size-dependent dendritic maladaptations of hypoglossal motor neurons in SOD1G93A mice. Anatomical Record, 304 (7), 1562-1581. doi: 10.1002/ar.24542

TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cells

Ding, Qiao, Chaplin, Justin, Morris, Matthew J., Hilliard, Massimo A., Wolvetang, Ernst, Ng, Dominic C. H. and Noakes, Peter G. (2021). TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cells. Frontiers in Cell and Developmental Biology, 9 611601, 611601. doi: 10.3389/fcell.2021.611601

Activity-dependent global downscaling of evoked neurotransmitter release across glutamatergic inputs in Drosophila

Karunanithi, Shanker, Lin, Yong Qi, Odierna, G. Lorenzo, Menon, Hareesh, Gonzalez, Juan Mena, Neely, G Gregory, Noakes, Peter G., Lavidis, Nickolas A., Moorhouse, Andrew J. and van Swinderen, Bruno (2020). Activity-dependent global downscaling of evoked neurotransmitter release across glutamatergic inputs in Drosophila. The Journal of Neuroscience, 40 (42), 8025-8041. doi: 10.1523/JNEUROSCI.0349-20.2020

Dscam2 suppresses synaptic strength through a PI3K-dependent endosomal pathway

Odierna, G. Lorenzo, Kerwin, Sarah K., Harris, Lucy E., Shin, Grace Ji-eun, Lavidis, Nickolas A., Noakes, Peter G. and Millard, S. Sean (2020). Dscam2 suppresses synaptic strength through a PI3K-dependent endosomal pathway. Journal of Cell Biology, 219 (6) e201909143. doi: 10.1083/jcb.201909143

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

Ferreira, Nicola, Andoniou, Christopher E., Perks, Kara L., Ermer, Judith A., Rudler, Danielle L., Rossetti, Giulia, Periyakaruppiah, Ambika, Wong, Jamie K Y, Rackham, Oliver, Noakes, Peter G., Degli-Esposti, Mariapia A. and Filipovska, Aleksandra (2020). Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS Genetics, 16 (3) e1008604, e1008604. doi: 10.1371/journal.pgen.1008604

Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice

Kumar, Vinod, Lee, John D., Clark, Richard J., Noakes, Peter G., Taylor, Stephen M. and Woodruff, Trent M. (2020). Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice. ACS Omega, 5 (5) acsomega.9b03735, 2345-2354. doi: 10.1021/acsomega.9b03735

What are neurotransmitter release sites and do they interact?

Ge, Dengyun, Noakes, Peter G. and Lavidis, Nickolas A. (2020). What are neurotransmitter release sites and do they interact?. Neuroscience, 425, 157-168. doi: 10.1016/j.neuroscience.2019.11.017

Size-dependent vulnerability of lumbar motor neuron dendritic degeneration in SOD1(G93A) mice

Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2019). Size-dependent vulnerability of lumbar motor neuron dendritic degeneration in SOD1(G93A) mice. The Anatomical Record, 303 (5) ar.24255, 1455-1471. doi: 10.1002/ar.24255

The Role of Altered BDNF/TrkB Signaling in Amyotrophic Lateral Sclerosis

Pradhan, Jonu, Noakes, Peter G. and Bellingham, Mark C. (2019). The Role of Altered BDNF/TrkB Signaling in Amyotrophic Lateral Sclerosis. Frontiers in Cellular Neuroscience, 13 368, 368. doi: 10.3389/fncel.2019.00368

Revisiting the role of the innate immune complement system in ALS

Parker, Sandra E., Hanton, Angela M., Stefanou, Stephen N., Noakes, Peter G., Woodruff, Trent M. and Lee, John D. (2019). Revisiting the role of the innate immune complement system in ALS. Neurobiology of Disease, 127, 223-232. doi: 10.1016/j.nbd.2019.03.003

A seasonal comparison of the neuromuscular junction morphology of Bufo marinus

Ge, Dengyun, Noakes, Peter G. and Lavidis, Nickolas A. (2019). A seasonal comparison of the neuromuscular junction morphology of Bufo marinus. Journal of Comparative Neurology, 527 (12), 1931-1939. doi: 10.1002/cne.24661

Complement components are upregulated and correlate with disease progression in the TDP-43 mouse model of amyotrophic lateral sclerosis

Lee, John D., Levin, Samantha C., Willis, Emily F., Li, Rui, Woodruff, Trent M. and Noakes, Peter G. (2018). Complement components are upregulated and correlate with disease progression in the TDP-43 mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 15 (1) 171, 171. doi: 10.1186/s12974-018-1217-2

Regulated alternative splicing of Drosophila Dscam2 is necessary for attaining the appropriate number of photoreceptor synapses

Kerwin, Sarah K., Li, Joshua Shing Shun, Noakes, Peter G., Shin, Grace Ji-eun and Millard, S. Sean (2018). Regulated alternative splicing of Drosophila Dscam2 is necessary for attaining the appropriate number of photoreceptor synapses. Genetics, 208 (2), 717-728. doi: 10.1534/genetics.117.300432

Defects in synaptic transmission at the neuromuscular junction precedes motor deficits in a TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis

Chand, Kirat K., Lee, Kah Meng, Lee, John D., Qiu, Hao, Willis, Emily F., Lavidis, Nickolas A., Hilliard, Massimo A. and Noakes, Peter G. (2018). Defects in synaptic transmission at the neuromuscular junction precedes motor deficits in a TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 32 (5), fj201700835R-2689. doi: 10.1096/fj.201700835R

Investigating methodological differences in the assessment of dendritic morphology of basolateral amygdala principal neurons – a comparison of Golgi-Cox and neurobiotin electroporation techniques

Klenowski, Paul M., Wright, Sophie E., Mu, Erica W.H., Noakes, Peter G., Lavidis, Nickolas A., Bartlett, Selena E., Bellingham, Mark C. and Fogarty, Matthew J. (2017). Investigating methodological differences in the assessment of dendritic morphology of basolateral amygdala principal neurons – a comparison of Golgi-Cox and neurobiotin electroporation techniques. Brain Sciences, 7 (12) 165, 1-12. doi: 10.3390/brainsci7120165

Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model

Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G. and Bellingham, Mark C. (2017). Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model. Frontiers in Neuroscience, 11 (NOV) 609, 1-16. doi: 10.3389/fnins.2017.00609

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1

Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Wang, Haitao A., Lee, John D., Lee, Kah Meng, Woodruff, Trent M. and Noakes, Peter G. (2017). Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. Skeletal Muscle, 7 (1) 10, 10. doi: 10.1186/s13395-017-0128-8

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Lee, John D., Kumar, Vinod, Fung, Jenny N. T., Ruitenberg, Marc J., Noakes, Peter G. and Woodruff, Trent M. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730

Alterations in hypoglossal motor neurons due to GAD67 and VGAT deficiency in mice

Fogarty, Matthew J., Kanjhan, Refik, Yanagawa, Yuchio, Noakes, Peter G. and Bellingham, Mark C. (2017). Alterations in hypoglossal motor neurons due to GAD67 and VGAT deficiency in mice. Experimental Neurology, 289, 117-127. doi: 10.1016/j.expneurol.2016.12.004

Functional decline at the aging neuromuscular junction is associated with altered laminin-α4 expression

Lee, Kah Meng, Chand, Kirat K., Hammond, Luke A., Lavidis, Nickolas A. and Noakes , Peter G. (2017). Functional decline at the aging neuromuscular junction is associated with altered laminin-α4 expression. Aging, 9 (3), 880-899. doi: 10.18632/aging.101198

Loss of laminin-alpha4 results in pre- and postsynaptic modifications at the neuromuscular junction

Chand, Kirat K., Lee, Kah Meng, Lavidis, Nickolas A. and Noakes, P. G. (2016). Loss of laminin-alpha4 results in pre- and postsynaptic modifications at the neuromuscular junction. FASEB Journal, 31 (4), 1323-1336. doi: 10.1096/fj.201600899R

Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis

Fogarty, Matthew J., Klenowski, Paul M., Lee, John D., Drieberg-Thompson, Joy R., Bartlett, Selena E., Ngo, Shyuan T., Hilliard, Massimo A., Bellingham, Mark C. and Noakes, Peter G. (2016). Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis. Scientific Reports, 6 (1) 37968, 37968. doi: 10.1038/srep37968

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. Journal of Leukocyte Biology, 101 (4), 927-947. doi: 10.1189/jlb.4VMA0716-316R

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. Human Molecular Genetics, 26 (1), 109-123. doi: 10.1093/hmg/ddw371

Marked changes in dendritic structure and spine density precede significant neuronal death in vulnerable cortical pyramidal neuron populations in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Fogarty, Matthew J., Mu, Erica W. H., Noakes, Peter G., Lavidis, Nickolas A. and Bellingham, Mark C. (2016). Marked changes in dendritic structure and spine density precede significant neuronal death in vulnerable cortical pyramidal neuron populations in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica Communications, 4 (77) 77, 1-21. doi: 10.1186/s40478-016-0347-y

Tick holocyclotoxins trigger host paralysis by presynaptic inhibition

Chand, Kirat K., Lee, Kah Meng, Lavidis, Nickolas A., Rodriguez-Valle, Manuel, Ijaz, Hina, Koehbach, Johannes, Clark, Richard J., Lew-Tabor, Ala and Noakes, Peter G. (2016). Tick holocyclotoxins trigger host paralysis by presynaptic inhibition. Scientific Reports, 6 (1) 29446, 29446. doi: 10.1038/srep29446

Glycinergic neurotransmission: A potent regulator of embryonic motor neuron dendritic morphology and synaptic plasticity

Fogarty, Matthew J., Kanjhan, Refik, Bellingham, Mark C. and Noakes, Peter G. (2016). Glycinergic neurotransmission: A potent regulator of embryonic motor neuron dendritic morphology and synaptic plasticity. Journal of Neuroscience, 36 (1), 80-87. doi: 10.1523/JNEUROSCI.1576-15.2016

Emerging roles of filopodia and dendritic spines in motoneuron plasticity during development and disease

Kanjhan, Refik, Noakes, Peter G. and Bellingham, Mark C. (2016). Emerging roles of filopodia and dendritic spines in motoneuron plasticity during development and disease. Neural Plasticity, 2016 3423267, 3423267.1-3423267.31. doi: 10.1155/2016/3423267

Developmental changes in the morphology of mouse hypoglossal motor neurons

Kanjhan, Refik, Fogarty, Matthew J., Noakes, Peter G. and Bellingham, Mark C. (2015). Developmental changes in the morphology of mouse hypoglossal motor neurons. Brain Structure and Function, 221 (7), 1-32. doi: 10.1007/s00429-015-1130-8

Structural and functional characterization of dendritic arbors and GABaergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala

Klenowski, Paul M., Fogarty, Matthew J., Belmer, Arnauld, Noakes, Peter G., Bellingham, Mark C. and Bartlett, Selena E. (2015). Structural and functional characterization of dendritic arbors and GABaergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala. Journal of Neurophysiology, 114 (2), 942-957. doi: 10.1152/jn.00824.2014

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1^G93A mouse model of amyotrophic lateral sclerosis

Lee, Jia Y., Lee, John D., Phipps, Simon, Noakes, Peter G. and Woodruff, Trent M. (2015). Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 12 (1) 90, 90. doi: 10.1186/s12974-015-0310-z

Motor cortex layer V pyramidal neurons exhibit dendritic regression, spine loss, and increased synaptic excitation in the presymptomatic hSOD1G93A mouse model of amyotrophic lateral sclerosis

Fogarty, Matthew J., Noakes, Peter G. and Bellingham, Mark C. (2015). Motor cortex layer V pyramidal neurons exhibit dendritic regression, spine loss, and increased synaptic excitation in the presymptomatic hSOD1G93A mouse model of amyotrophic lateral sclerosis. Journal of Neuroscience, 35 (2), 643-647. doi: 10.1523/JNEUROSCI.3483-14.2015

Genetic absence of the vesicular inhibitory amino acid transporter differentially regulates respiratory and locomotor motor neuron development

Fogarty, Matthew J., Yanagawa, Yuchio, Obata, Kunihiko, Bellingham, Mark C. and Noakes, Peter G. (2015). Genetic absence of the vesicular inhibitory amino acid transporter differentially regulates respiratory and locomotor motor neuron development. Brain Structure and Function, 220 (1), 525-540. doi: 10.1007/s00429-013-0673-9

Loss of β2-laminin alters calcium sensitivity and voltage gated calcium channel maturation of neurotransmission at the neuromuscular junction

Chand, Kirat K., Lee, Kah Meng, Schenning, Mitja P., Lavidis, Nickolas A. and Noakes, Peter G. (2015). Loss of β2-laminin alters calcium sensitivity and voltage gated calcium channel maturation of neurotransmission at the neuromuscular junction. Journal of Physiology, 593 (1), 245-265. doi: 10.1113/jphysiol.2014.284133

Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood

Mantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005

Role for terminal complement activation in amyotrophic lateral sclerosis disease progression

Woodruff, Trent M., Lee, John D. and Noakes, Peter G. (2014). Role for terminal complement activation in amyotrophic lateral sclerosis disease progression. Proceeding of the National Academy of Sciences of the United States of America, 111 (1), E3-E4. doi: 10.1073/pnas.1321248111

A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs

Fogarty, Matthew J., Hammond, Luke A., Kanjhan, Refik, Bellingham, Mark C. and Noakes, Peter G. (2013). A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs. Frontiers in Neural Circuits, 7 (OCT) 153, 1-18. doi: 10.3389/fncir.2013.00153

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain

Narayanan, Ramesh K., Mangelsdorf, Marie, Panwar, Ajay, Butler, Tim J., Noakes, Peter G. and Wallace, Robyn H. (2013). Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (4), 252-260. doi: 10.3109/21678421.2012.734520

Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development

Fogarty, Matthew J., Smallcombe, Karen L., Yanagawa, Yuchio, Obata, Kunihiko, Bellingham, Mark C. and Noakes, Peter G. (2013). Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development. PLoS One, 8 (2) e56257, e56257. doi: 10.1371/journal.pone.0056257

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation

Ngo, Shyuan T., Cole, Rebecca N., Sunn, Nana, Phillips, William D. and Noakes, Peter G. (2012). Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation. Journal of Cell Science, 125 (6), 1531-1543. doi: 10.1242/jcs.095109

Muscle Specific Kinase: Organiser of synaptic membrane domains

Ghazanfari, Nazanin, Fernandez, Kristine J., Murata, Yui, Morsch, Marco, Ngo, Shyuan T., Reddel, Stephen W., Noakes, Peter G. and Phillips, William D. (2011). Muscle Specific Kinase: Organiser of synaptic membrane domains. The International Journal of Biochemistry and Cell Biology, 43 (3), 295-298. doi: 10.1016/j.biocel.2010.10.008

The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges

Kanjhan, Refik, Pow, David V., Noakes, Peter G. and Bellingham, Mark C. (2010). The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges. Journal of Molecular Histology, 41 (6), 315-323. doi: 10.1007/s10735-010-9293-3

Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

Azhar, M, Wang, PY, Frugier, T, Koishi, K, Deng, CX, Noakes, PG and McLennan, IS (2010). Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract. International Journal of Biological Sciences, 6 (6), 546-555. doi: 10.7150/ijbs.6.546

The role of the complement system and the activation fragment C5a in the central nervous system

Woodruff, T. M., Ager, R. R., Tenner, A. J., Noakes, P. G. and Taylor, S. M. (2010). The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medecine, 12 (2), 179-192. doi: 10.1007/s12017-009-8085-y

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

Muttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h

In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2

Barclay, Johanna L., Kerr, Linda M., Arthur, Leela, Rowland, Jennifer E., Nelson, Caroline N., Ishikawa, Mayumi, d'Aniello, Elisabetta M., White, Mary, Noakes, Peter G. and Waters, Michael J. (2010). In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2. Molecular Endocrinology, 24 (1), 204-217. doi: 10.1210/me.2009-0233

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

Crane, James W., Baiquni, Gilang P., Sullivan, Robert K. P., Lee, John D, Sah, Pankaj, Taylor, Stephen M, Noakes, Peter G. and Woodruff, Trent (2009). The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres. Journal of Neuroinflammation, 6 (34) 34, 34.1-34.10. doi: 10.1186/1742-2094-6-34

The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis

Woodruff, Trent M., Costantini, Kerina J., Crane, James W., Atkin, Julie D., Monk, Peter N., Taylor, Stephen M. and Noakes, Peter G. (2008). The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis. Journal of Immunology, 181 (12), 8727-8734. doi: 10.4049/jimmunol.181.12.8727

Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors

Woodruff, Trent M., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors. Advances in Experimental Medicine and Biology, 632, 143-158.

Neural agrin increases postsynaptic ACh receptor packing by elevating rapsyn protein at the mouse neuromuscular synapse

Brockhausen, J., Cole, R. N., Gervasio, O. L., Ngo, S. T., Noakes, P. G. and Phillips, W. D. (2008). Neural agrin increases postsynaptic ACh receptor packing by elevating rapsyn protein at the mouse neuromuscular synapse. Developmental Neurobiology, 68 (9), 1153-1169. doi: 10.1002/dneu.20654

GABA-deficient mice produce regional alterations in motoneuron survival during neural development

Noakes, P. G., Smallcombe, K., Arata, A., Obata, A., Davies, J. and Bellingham, M. C. (2007). GABA-deficient mice produce regional alterations in motoneuron survival during neural development. The Society for Neuroscience Abstracts, 27 (33).

IGF-I and insulin activate mitogen-activated protein kinase via the type 1 IGF receptor in mouse embryonic stem cells

Nguyen, T. T., Sheppard, A. M., Kaye, P. L. and Noakes, P. G. (2007). IGF-I and insulin activate mitogen-activated protein kinase via the type 1 IGF receptor in mouse embryonic stem cells. Reproduction, 134 (1), 41-49. doi: 10.1530/REP-06-0087

Neural agrin: A synaptic stabiliser

Ngo, Shyuan T., Noakes, Peter G. and Phillips, William D. (2007). Neural agrin: A synaptic stabiliser. International Journal of Biochemistry & Cell Biology, 39 (5), 863-867. doi: 10.1016/j.biocel.2006.10.012

Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain

Barclay, M, Noakes, PG, Ryan, AF, Julien, JP and Housley, GD (2007). Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain. Histochemistry And Cell Biology, 128 (6), 541-550. doi: 10.1007/s00418-007-0340-4

Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction

Chen, F, Qian, L, Yang, ZH, Huang, Y, Ngo, ST, Ruan, NJ, Wang, J, Schneider, C, Noakes, PG, Ding, YQ, Mei, L and Luo, ZG (2007). Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction. Neuron, 55 (2), 247-260. doi: 10.1016/j.neuron.2007.06.031

Targeting of the ETS factor Gabp alpha disrupts neuromuscular junction synaptic function

O'Leary, Debra A., Noakes, Peter G., Lavidis, Nick A., Kola, Ismail, Hertzog, Paul J. and Ristevski, Sika (2007). Targeting of the ETS factor Gabp alpha disrupts neuromuscular junction synaptic function. Molecular and Cellular Biology, 27 (9), 3470-3480. doi: 10.1128/MCB.00659-06

Developmental regulation of the neuromotor circuit: peripheral and central synaptic influences in motoneuron numbers and innervation of muscle

Noakes, P. G., Smallcombe, K. L., Kanjhan, R., Arata, A., Banks, G., Obata, K., Betz, H. and Bellingham, M. C. (2006). Developmental regulation of the neuromotor circuit: peripheral and central synaptic influences in motoneuron numbers and innervation of muscle. Proceedings of the Australian Society for Biochemistry and Molecular Biology, 38, SYM-57-03-SYM-57-03.

Erratum: Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation

Banks, Glen B., Kanjhan, Refik, Wiese, Stefan, Kneussel, Matthias, Wong, Loke M., O'Sullivan, Gregory, Sendtner, Michael, Bellingham, Mark C., Betz, Heinrich and Noakes, Peter G. (2005). Erratum: Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. Journal of Neuroscience, 25 (11), 3018-3021.

In vivo analysis of growth hormone receptor signaling domains and their associated transcripts

Rowland, Jennifer E., Lichanska, Agnieszka M., Kerr, Linda M., White, Mary, d'Aniello, Elisabetta M., Maher, Sheryl L., Brown, Richard, Teasdale, Rohan D., Noakes, Peter G. and Waters, Michael J. (2005). In vivo analysis of growth hormone receptor signaling domains and their associated transcripts. Molecular and Cellular Biology, 25 (5), 2072-2072. doi: 10.1128/MCB.25.5.2072.2005

Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation

Banks, GB, Kanjhan, R, Wiese, S, Kneussel, M, Wong, LM, O'Sullivan, G, Sendtner, M, Bellingham, MC, Betz, H and Noakes, PG (2005). Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. Journal of Neuroscience, 25 (5), 1249-1259. doi: 10.1523/JNEUROSCI.1786-04.2005

Heterozygote effects in mice with partial truncations in the growth hormone receptor cytoplasmic domain: Assessment of growth parameters and phenotype

Rowland, J. E., Kerr, Linda M., White, Mary, Noakes, Peter G. and Waters, Michael J. (2005). Heterozygote effects in mice with partial truncations in the growth hormone receptor cytoplasmic domain: Assessment of growth parameters and phenotype. Endocrinology, 146 (12), 5278-5286. doi: 10.1210/en.2005-0939

In vivo analysis of growth hormone receptor signaling domains and their associated transcripts

Rowland, Jennifer E., Lichanska, Agnieszka M., Kerr, Linda M., White, Mary, d'Aniello, Elisabetta M., Maher, Sheryl L., Brown, Richard, Teasdale, Rohan D., Noakes, Peter G. and Waters, Michael J. (2005). In vivo analysis of growth hormone receptor signaling domains and their associated transcripts. Molecular And Cellular Biology, 25 (5), 66-77. doi: 10.1128/MCB.25.1.66-77.2005

Postnatal changes in TASK-1 and TREK-1 expression in rat brain stem and cerebellum

Kanjhan, Refik, Anselme, Amy, Noakes, Peter and Bellingham, Mark (2004). Postnatal changes in TASK-1 and TREK-1 expression in rat brain stem and cerebellum. Neuroreport, 15 (8), 1321-1324. doi: 10.1097/01.wnr.0000127462.15985.dc

Developmental expression of two-pore domain K+ channels, TASK-1 and TREK-1, in the rat cochlea

Kanjhan, Refik, Balke, Caroline, Housley, Gary, Bellingham, Mark and Noakes, Peter (2004). Developmental expression of two-pore domain K+ channels, TASK-1 and TREK-1, in the rat cochlea. Neuroreport, 15 (3), 437-441. doi: 10.1097/01.wnr.0000114978.66165.39

Neuregulin potentiates agrin-induced acetylcholine receptor clustering in myotubes

Ngo, S. T., Balke, C., Phillips, W. D. and Noakes, P. G. (2004). Neuregulin potentiates agrin-induced acetylcholine receptor clustering in myotubes. Neuroreport, 15 (16), 2501-2505. doi: 10.1097/00001756-200411150-00014

P2x(7)-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms

Ireland, M. F., Noakes, P. G. and Bellingham, M. C. (2004). P2x(7)-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms. Neuroscience, 128 (2), 269-280. doi: 10.1016/j.neuroscience.2004.06.014

Genetic disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse

Parsons, Sean A., Banks, Glen B., Rowland, Jenny A., Coschigano, Karen T., Kopchick, John J., Waters, Michael J. and Noakes, Peter G. (2003). Genetic disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse. International Journal of Developmental Biology, 47 (1), 41-49. doi: 10.1387/15

Functional analysis of neurotransmission at β2-laminin deficient terminals

Knight, D., Tolley, L. K., Kim, D. K., Lavidis, N. A. and Noakes, P. G. (2003). Functional analysis of neurotransmission at β2-laminin deficient terminals. The Journal of Physiology, 546 (3), 789-800. doi: 10.1113/jphysiol.2002.030924

Neuromuscular synapses mediate motor axon branching and motoneuron survival during the embryonic period of programmed cell death

Banks, G. B., Choy, P. T., Lavidis, N. A. and Noakes, P. G. (2003). Neuromuscular synapses mediate motor axon branching and motoneuron survival during the embryonic period of programmed cell death. Developmental Biology, 257 (1), 71-84. doi: 10.1016/S0012-1606(03)00056-3

Elucidating the molecular mechanisms that underlie the target control of motoneuron death

Banks, Glen B. and Noakes, Peter G. (2002). Elucidating the molecular mechanisms that underlie the target control of motoneuron death. International Journal of Developmental Biology, 46 (4), 551-558.

Erratum: Alterations in ciliary neurotrophic factor signalling in rapsyn deficient mice (Journal of Neuroscience Research (64) 6 (575-581))

Bartlett, S. E., Banks, G., Reynolds, A. J., Waters, M. J., Hendry, I. A. and Noakes, P. G. (2001). Erratum: Alterations in ciliary neurotrophic factor signalling in rapsyn deficient mice (Journal of Neuroscience Research (64) 6 (575-581)). Journal of Neuroscience Research, 66 (4), 731-732. doi: 10.1002/jnr.10070

Alterations in ciliary neurotrophic factor signaling in rapsyn deficient mice

Bartlett, Selena E., Banks, Glen B., Reynolds, Anna J., Waters, Mike J., Hendry, Ian A. and Noakes, Peter G. (2001). Alterations in ciliary neurotrophic factor signaling in rapsyn deficient mice. Journal of Neuroscience Research, 64 (6), 575-581. doi: 10.1002/jnr.1109

Promotion of motoneuron survival and branching in rapsyn-deficient mice

Banks, G. B., Chau, T. N. P., Bartlett, S. E. and Noakes, P. G. (2001). Promotion of motoneuron survival and branching in rapsyn-deficient mice. Journal of Comparative Neurology, 429 (1), 156-165. doi: 10.1002/1096-9861(20000101)429:1<156::AID-CNE12>3.0.CO;2-3

Transport of endosomal early antigen I in the rat sciatic nerve and location in cultured neurons

Bartlett, S. E., Reynolds, A. J., Weible, M., Noakes, P. G. and Hendry, I. A. (2001). Transport of endosomal early antigen I in the rat sciatic nerve and location in cultured neurons. Neuroreport, 12 (2), 281-284. doi: 10.1097/00001756-200102120-00020

Alterations in ciliary neurotrophic factor signaling in rapsyn deficient mice

Bartlett, S. E., Banks, G. B. and Noakes P. G. (2000). Alterations in ciliary neurotrophic factor signaling in rapsyn deficient mice. Journal of Neuroscience Research, 64 (6), 575-581.

Over expression of rapsyn inhibits agrin-induced acetylcholine receptor clustering in muscle cells

Han, Hong, Noakes, Peter G. and Phillips, William D. (1999). Over expression of rapsyn inhibits agrin-induced acetylcholine receptor clustering in muscle cells. Journal of neurocytology, 28 (9), 763-775. doi: 10.1023/A:1007098406748

Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation

Noakes, P. G., Chin, D., Kim, S. S., Liang, S. and Phillips, W. D. (1999). Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. Journal of Comparative Neurology, 410 (4), 531-540. doi: 10.1002/(SICI)1096-9861(19990809)410:4<531::AID-CNE2>3.0.CO;2-C

Role of rapsyn in agrin-mediated acetylcholine receptor clustering

Han, H, Noakes, PG and Phillips, WD (1998). Role of rapsyn in agrin-mediated acetylcholine receptor clustering. Journal of Neurochemistry, 70, S36-S36.

Rapsyn and agrin slow the metabolic degradation of the acetylcholine receptor

Phillips, William D., Vladeta, Daniel, Han, Hong and Noakes, Peter G. (1997). Rapsyn and agrin slow the metabolic degradation of the acetylcholine receptor. Molecular and Cellular Neuroscience, 10 (1-2), 16-26. doi: 10.1006/mcne.1997.0634

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

Gautam, M., Noakes, P.G., Moscoso, L., Rupp, F., Scheller, R.H., Merlie, J.P. and Sanes, (1996). Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell, 85 (4), 525-535. doi: 10.1016/S0092-8674(00)81253-2

Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle

Moscoso, Lisa M., Chu, Gerald C., Gautam, Medha, Noakes, Peter G., Merlie, John P. and Sanes, Joashua R. (1995). Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle. Developmental Biology, 172 (1), 158-169. doi: 10.1006/dbio.1995.0012

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

Gautam, Medha, Noakes, Peter G., Mudd, Jacqueline, Nichol, Mia, Chu, Gerald C., Sanes, Joshua R. and Merlie John P. (1995). Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice. Nature, 377 (6546), 232-236. doi: 10.1038/377232a0

The renal glomerulus of mice lacking s–laminin/laminin β2: nephrosis despite molecular compensation by laminin β1

Noakes, Peter G. , Miner, Jeffrey H. , Gautam, Medha , Cunningham, Jeanette M. , Sanes, Joshua R. and Merlie, John P. (1995). The renal glomerulus of mice lacking s–laminin/laminin β2: nephrosis despite molecular compensation by laminin β1. Nature Genetics, 10 (4), 400-406. doi: 10.1038/ng0895-400

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2

Noakes, Peter G., Gautam, Medha, Mudd, Jacqueline, Sanes, Joshua R. and Merlie, John P. (1995). Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2. Nature, 374 (6519), 258-262. doi: 10.1038/374258a0

Expanding roles for α4 integrin and its ligands in development

Sheppard, Allan M., Onken, Michael D., Rosen, Clknn D., Noakes, Peter G. and Dean, Douglas C. (1994). Expanding roles for α4 integrin and its ligands in development. Cell Adhesion and Communication, 2 (1), 27-43. doi: 10.3109/15419069409014200

Clustering and immobilization of acetylcholine receptors by the 43-kD protein: a possible role for dystrophin-related protein

Phillips, W. D., Noakes, P. G., Roberds, S. L., Campbell, K. P. and Merlie, J. P. (1993). Clustering and immobilization of acetylcholine receptors by the 43-kD protein: a possible role for dystrophin-related protein. Journal of Cell Biology, 123 (3), 729-740. doi: 10.1083/jcb.123.3.729

43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo

Noakes, Peter G., Phillips, William D., Hanley, Theresa A., Sanes, Joshua R. and Merlie, John P. (1993). 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Developmental Biology, 155 (1), 275-280. doi: 10.1006/dbio.1993.1025

The relationship between migrating neural crest cells and growing limb nerves in the developing chick forelimb

Noakes, Peter G., Hornbusch, Amarta and Wolpert, Lewis (1993). The relationship between migrating neural crest cells and growing limb nerves in the developing chick forelimb. Progress in Clinical and Biological Research, 383A ISBN 0-471-5994-5, 381-390.

Migration of schwann cells and axons into developing chick forelimb muscles following removal of either the neural tube or the neural crest

Noakes, Peter G., Bennett, Max R. and Stratford, Jacqueline (1988). Migration of schwann cells and axons into developing chick forelimb muscles following removal of either the neural tube or the neural crest. The Journal of Comparative Neurology, 277 (2), 214-233. doi: 10.1002/cne.902770205

Growth of axons into developing muscles of the chick forelimb is preceded by cells that stain with Schwann cell antibodies

Noakes, Peter G. and Bennett, Max R. (1987). Growth of axons into developing muscles of the chick forelimb is preceded by cells that stain with Schwann cell antibodies. The Journal of Comparative Neurology, 259 (3), 330-347. doi: 10.1002/cne.902590303

The growth of muscle nerves in relation to the formation of primary myotubes in the developing chick forelimb

Noakes, Peter G., Everett, Alan W. and Bennett, Max R. (1986). The growth of muscle nerves in relation to the formation of primary myotubes in the developing chick forelimb. The Journal of Comparative Neurology, 248 (2), 245-256. doi: 10.1002/cne.902480207

Growth of segmental nerves to the developing rat diaphragm: absence of pioneer axons

Noakes, P. G., Bennett, M. R. and Davey, D. F. (1983). Growth of segmental nerves to the developing rat diaphragm: absence of pioneer axons. The Journal of Comparative Neurology, 218 (4), 365-377. doi: 10.1002/cne.902180402

IVT-14 Layer V pyramidal neurons showing synaptic hyper-excitability has altered TrkB receptor signaling in SOD1G3A mouse model of ALS

Pradhan, Jonu, Noakes, Peter G. and Bellingham, Mark C. (2018). IVT-14 Layer V pyramidal neurons showing synaptic hyper-excitability has altered TrkB receptor signaling in SOD1G3A mouse model of ALS. 29th International Symposium on ALS/MND, Glasgow, Scotland, 7-9 December 2018. Abingdon, Oxfordshire, United Kingdom: Taylor & Francis. doi: 10.1080/21678421.2018.1510569

Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia

Quek, H., Luff, J., Cheung, K., Kozlov, S., Gatei, M., Lee, C. S., Bellingham, M., Noakes, P., Lim, Y. C., Barnett, N., Dingwall, S., Wolvetang, E., Mashimo, T., Roberts, T. and Lavin, M. (2016). Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200

Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration

Kumar, Vinod, Lee, John, Noakes, Peter and Woodruff, Trent (2015). Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration. 8th International Conference on Complement Therapeutics, Chania, Crete, Greece, 1-6 January 2015.

Peripheral immune complement activation in neurodegenerative disease

Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188

A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment

Fogarty, M. J., Hammond, L. A., Kanjhan, R., Bellingham, M. C. and Noakes, P. G. (2013). A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment. Neuroscience 2013: 43rd Annual Meeting of the Society for Neuroscience, San Diago, CA, United States, 9-13 November, 2012.

Dysregulation of the complement system in neurodegenerative disease

Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.215

Neuregulin Modulates Acetylcholine Receptor Clustering via Non-transcriptional Mechanisms

Shyuan, N., Cole, R. N., Sunn, N., Phillips, W. D. and Noakes, P. G. (2009). Neuregulin Modulates Acetylcholine Receptor Clustering via Non-transcriptional Mechanisms. ANS 29th Annual meeting 2009, Canberra, ACT, 27 - 30 January, 2009. Online: Australian Neuroscience Society.

Neuregulin Modulates Agrin-Induced Acetylcholine Receptor Clustering via MuSK Phosphorylation.

Ngo, Shyuan T., Cole, R. N., Sunn, Nana, Phillips, W. D. and Noakes, Peter G. (2009). Neuregulin Modulates Agrin-Induced Acetylcholine Receptor Clustering via MuSK Phosphorylation.. Neuroscience 2009, SfN's 39th annual meeting, Chicago, IL, U.S., 17-21 October 2009.

Neuregulin potentiates agrin-induced acetylcholine receptor clustering via a non-transcriptional mechanism in skeletal muscles

Ngo, S.T., Cole, R.N., Sunn, N., Phillips, W.D. and Noakes, P.G. (2009). Neuregulin potentiates agrin-induced acetylcholine receptor clustering via a non-transcriptional mechanism in skeletal muscles. 9th Hunter Valley Cellular Biology Meeting, Hunter Valley, NSW, Australia, 23-25 September 2009.

Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis

Woodruff, Trent, Denny, Kerina, Crane, James, Atkin, Julie, Taylor, Steve and Noakes, Peter (2008). Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September-02 October 2008. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2008.08.202

Molecular mechanisms underlying the regulation of the clustering and dispersal of acetylcholine receptors in skeletal muscle

Ngo, S. T., Cole, R. N., Phillips, W. D. and Noakes, Peter G. (2008). Molecular mechanisms underlying the regulation of the clustering and dispersal of acetylcholine receptors in skeletal muscle. ComBio 2008, Canberra, Australia, 21-25 September, 2008. Kent Town, South Australia: Australian Society for Biochemistry and Molecular Biology.

Nerve to Muscle Signalling in Myasthenia Gravis

Ngo, S. T., Cole, R. N., Phillips, W. D. and Noakes, P. G. (2008). Nerve to Muscle Signalling in Myasthenia Gravis. Australian Society for Medical Research, PA Hospital, Brisbane, Australia, May 2008.

Role of complement in motor neuron disease: Animal models and therapeutic potential of complement inhibitors

Woodruff, Trent R., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: Animal models and therapeutic potential of complement inhibitors. 4th Aegean Workshop on Complement Associated Diseases, Animal Models and Therapeutics, Porto Heli, Greece, 10-17 June 2007. New York, United States: Springer New York LLC. doi: 10.1007/978-0-387-78952-1_11

Selenocysteine in peptide drug design

Adams, D. J., Alewood, P. F., Choy, P. T., Craik, D. J., Daly, N. L., Grishin, A. A., Hu, S-H., Martin, J. L., Muttenthaler, M., Nevin, S. T., Ngo, S. T. and Noakes, P. G. (2008). Selenocysteine in peptide drug design. Royal Australian Chemical Institute (RACI) Annual Scientific Meeting: Drug Discovery and Development, Couran Cove Island Resort, Queensland, Australia, 13 - 17 July 2008.

Selenocysteine in peptide folding and drug design

Muttenthaler, M., Nevin, S. T., Grishin, A. A., Ngo, S. T., Choy, P. T., Daly, N. L., Hu, S-H., Martin, J. L., Noakes, P. G., Craik, D. J., Adams, D. J. and Alewood, P. F. (2008). Selenocysteine in peptide folding and drug design. XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Vienna, Austria, 31 August - 4 September 2008.

Neuregulin modulates postsynaptic acetylcholine receptors at the neuromuscular synapse

Ngo, S. T., Phillips, W. D. and Noakes, P. G. (2007). Neuregulin modulates postsynaptic acetylcholine receptors at the neuromuscular synapse. ComBio 2007, Sydney , Australia, September 22-26 2007.

Regulatory Role of Neuregulin in Acetylcholine Receptor Clustering at the Neuromuscular Synapse

Ngo, S.T., Phillips, W.D. and Noakes, P.G. (2007). Regulatory Role of Neuregulin in Acetylcholine Receptor Clustering at the Neuromuscular Synapse. Annual Meeting of the Society for Neuroscience 2007, San Diego, CA, U.S.A., 3-7 November, 2007.

Signaling underlying postsynaptic differentiation at the neuro-muscular junction

Chen, Fei, Qian, Lei, Yang, Zhi-hua, Huang, Ying, Ngo, Shyuan T., Ruan, Nan-jie, Wang, Jia, Schneider, Claudio, Noakes, Peter G., Ding, Yu-qiang, Mei, Lin and Luo, Zhen-ge (2007). Signaling underlying postsynaptic differentiation at the neuro-muscular junction. The 19th Federation of Asian and Oceanian Biochemists and Molecular Biologists Inc. (FAOBMB) Meeting, Seoul, Korea, 27-31 May, 2007.

A lack of GABA produces regional alterations in motoneuron activity, motoneuron survival and innervation of mice during neural development

Noakes, Peter G., Smallcombe, Karen, Davis, Jonathan and Bellingham, Mark C. (2006). A lack of GABA produces regional alterations in motoneuron activity, motoneuron survival and innervation of mice during neural development. ComBio 2006, Brisbane, Australia, 24-28 September, 2006. Online:

Altered expression of MLF1 and Zyxin in response to genetic and physical disruption of neuromuscular synapses

Caudron, A. J., Lichanska, A.M., Cooper, H. M., Kato, N. Y. and Noakes, P. G. (2006). Altered expression of MLF1 and Zyxin in response to genetic and physical disruption of neuromuscular synapses. Australian Neuroscience Society, Sydney, NSW Australia, 2006.

Change in the sensitivity of transmitter release to calcium at beta 2 laminin deficient nerve terminals

Scheening, M., Noakes, P. G. and Lavidis, N. A. (2006). Change in the sensitivity of transmitter release to calcium at beta 2 laminin deficient nerve terminals. ComBio 2006, Brisbane, 24-28 September, 2006. Kent Town, SA: Australian Society for Biochemistry and Molecular Biology.

Decrease in spontaneous activity and cell death of the brachial motoneurons in GAD67-deficient mouse embryo

Arata, A., Obata, K., Davies, J., Bellingham, M. and Noakes, P. G. (2006). Decrease in spontaneous activity and cell death of the brachial motoneurons in GAD67-deficient mouse embryo. 29th Annual Meeting of the Japan Neuroscience Society, Kyoto, Japan, 19-21 July 2006. Clare: Elsevier Ireland Ltd. doi: 10.1016/j.neures.2006.04.004

Differential localization and expression of complement in a rat model of motor neuron disease

Denny, K. J., Crane, J. W., Taylor, S. M. and Noakes, P. G. (2006). Differential localization and expression of complement in a rat model of motor neuron disease. ComBio2006, Brisbane Convention & Exhibition Centre, Brisbane, Qld, Aust, 24-28 September 2006.

Neuregulin as a Regulator of Acetylcholine Receptor Clusters at the Neuromuscular Synapse

Ngo S. T., Phillips, W. D. and Noakes, P. G . (2006). Neuregulin as a Regulator of Acetylcholine Receptor Clusters at the Neuromuscular Synapse. 4th Congress of Federation of Asian-Oceanian Neuroscience Societies, Hong Kong, November 30 - December 2.

Neuregulin is a regulator of acetylcholine receptor clusters at the neuromuscular synapse

Ngo, S. T., Noakes, P. G. and Phillips, W. D. (2006). Neuregulin is a regulator of acetylcholine receptor clusters at the neuromuscular synapse. Kent Town, South Australia, 2006.

Neuregulin-1 Modulates Agrin-induced Acetylcholine Receptor Clustering

Shyuan, Ngo, Phillips, W. D. and Noakes, Peter G. (2006). Neuregulin-1 Modulates Agrin-induced Acetylcholine Receptor Clustering. The 26th annual meeting of the Australian Neuroscience Society, Sydney, Australia, 31 Jan - 3 Feb 2006. Amsterdam: Elsevier/North-Holland.

Role of central and peripheral synaptic connections in regulating developmental motoneuron cell death

Noakes, Peter G. (2006). Role of central and peripheral synaptic connections in regulating developmental motoneuron cell death. 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), Hong Kong, 30 November - 2 December, 2006.

Differential Expression of MRNA in MuSK-Deficient Mice

Caudron, A. J., Lichanska, A. M., Ngo, S. T., Cooper, H. M. and Noakes, P. G. (2005). Differential Expression of MRNA in MuSK-Deficient Mice. ComBio 2005, Adelaide, SA Australia, 25 - 29 September 2005.

Expression of TAU-GFP and UPRT in mammalian cells permits labelling and selective ablation

Barclay, M., Hoya, N., Huang, L-C., Greenwood, D., Noakes, P. G., Ryan, A. F. and Housley, G. D. (2005). Expression of TAU-GFP and UPRT in mammalian cells permits labelling and selective ablation. Proceedings of the Australian Neuroscience Society, xx, xx.

Neuregulin modulates agrin-induced acetylcholine receptor clustering in myotubes

Ngo, S. T., Phillips, W. D., Lavidis, N. A. and Noakes, P. G. (2005). Neuregulin modulates agrin-induced acetylcholine receptor clustering in myotubes. ComBio 2005, Adelaide, 25-29 September, 2005. Canberra, ACT: The Society for Biochemisty and Molecular Biology.

Regulation of Acetylcholine Receptor Clustering and Dispersal

Ngo, S.T., Noakes, P.G. and Phillips, W.D (2005). Regulation of Acetylcholine Receptor Clustering and Dispersal. 6th Hunter Valley Cellular Biology Meeting, The Sebel-Kirkton Park, Pokolbin, NSW, Australia, 6-8 April, 2005.

A new marker for the meningeo-glial network: a two pore domain K channel TASK1

Kanjhan, R., Pow, D.V., Birt, J.B., Noakes, P.G. and Bellingham, M.C. (2004). A new marker for the meningeo-glial network: a two pore domain K channel TASK1. Australian Neuroscience Society - 24th Annual Meeting, Melbourne, Australia, 27-30 January, 2004. Amsterdam: Elsevier/North-Holland.

Agrin and Heregulin induction of acetylcholine receptor clustering in C2C12 myotubes

Ngo, S. T., Nguyen T. T., Phillips, W. D. and Noakes, P. G. (2004). Agrin and Heregulin induction of acetylcholine receptor clustering in C2C12 myotubes. Proceedings of the Australian Neuroscience Society, Melbourne, 2004.

Expression of two pore domain K channels TASK1 and TREK1, in the rat cochlea: implications for Tinnitus

Noakes, Peter G., Kanjhan, Refik, Balke, Caroline L., Nguyen, Thanh T., Housley, G. and Bellingham, Mark C. (2004). Expression of two pore domain K channels TASK1 and TREK1, in the rat cochlea: implications for Tinnitus. Australian Neuroscience Society Meeting 24th Annual Meeting, Melbourne, 27-30 January, 2004. Melbourne: Australian Neuroscience Society.

HRG-Beta1 Treatment Myotubes Induces Genes Needed for Post-Synaptic and Muscle Development

Balke, C. L. and Noakes, Peter G. (2004). HRG-Beta1 Treatment Myotubes Induces Genes Needed for Post-Synaptic and Muscle Development. Proceedings of Australian Neuroscience Society, Melbourne, 2004.

Hypoglossal and spinal motor neural activity in gephyrin-deficient versus wild-type mice

Wong, L. M., Kanjhan, R., Bellingham, M. C. and Noakes, P. G. (2004). Hypoglossal and spinal motor neural activity in gephyrin-deficient versus wild-type mice. Australian Neuroscience Society, 24th Annual Meeeting, Melbourne, Australia, 27-30 January, 2004. Australia: Australian Neuroscience Society.

Locaization of TASK1 and TREK1 Two Pore Domain K Channels and P2Y2 and P2Y4 Receptors in Rat Hypoglossal Motoneurons

Bellingham, M. C., Kanjhan, R., Huang, L. C., Housley, G. D., Lipski, J., Funk, G. D. and Noakes, P. G. (2004). Locaization of TASK1 and TREK1 Two Pore Domain K Channels and P2Y2 and P2Y4 Receptors in Rat Hypoglossal Motoneurons. 24th Annual Meeting of the Australian Neuroscience Society, Melbourne, Australia, 27-30 January, 2004. Melbourne: Australian Neuroscience Inc.

Motoneuron survival in the absence of GABA and glycine neurotransmission during embryonic development

Banks, G., Bellingham, M., Kneussel, M., Sullivan, M., Betz, H. and Noakes, P. (2003). Motoneuron survival in the absence of GABA and glycine neurotransmission during embryonic development. Australian Neuroscience Society 23rd Annual Meeting, Adelaide, 28-31 January, 2003. Australia: Australian Neuroscience Sociey.

P2X7 receptors enhance excitatory central synaptic transmission

Birt, J., Ireland, M., Knight, D., Noakes, P. G. and Bellingham, M. (2003). P2X7 receptors enhance excitatory central synaptic transmission. Australian Neuroscience Society 23rd Annual Meeting, Adelaide, 28-31 January, 2003. Australia: Australian Neuroscience Sociey Inc..

The Use of Cell Type Specific Knockout Mice to Study the Roles of Synaptic Signalling Molecules in the Nervous System

Noakes, P. G., Koshi, K., Frugier, T., White, M., Bellingham, M. and Mclennan I. (2003). The Use of Cell Type Specific Knockout Mice to Study the Roles of Synaptic Signalling Molecules in the Nervous System. Australian Neurological Society Annual Conference, Adelaide, 2003.

Disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse

Parsons, S. A., Banks, G. B., Coschigano, K.T., Kopchick J. J., Waters, M. and Noakes, P. G. (2002). Disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse. ANS Annual Conference, Sydney, Australia, 2002. Kent Town SA: Australian Neuroscience Society.

Muscle activity controls the rate of motoneuron death and spatial restriction of neurite branching in agrin and rapsyn-deficient mice

Banks, G. and Noakes, P. (2002). Muscle activity controls the rate of motoneuron death and spatial restriction of neurite branching in agrin and rapsyn-deficient mice. Proceedings of the Australian Neuroscience Society 2001, Brisbane, 2001. Hackney, S.A.: The Australian Neuroscience Society.

Restriction of intramuscular neurite branching and extension is lost in agrin and rapsyn-deficient mice

Banks, G. and Noakes, P. G. (2002). Restriction of intramuscular neurite branching and extension is lost in agrin and rapsyn-deficient mice. 14th Biennial Meeting of the International Society for Developmental Neuroscience, Sydney, 31 January-4February 2002. doi: 10.1016/S0736-5748(01)00060-0

Role of P2X7 receptors in transmitter release in mice

Knight, D., Ireland, M. F., Bellingham, M. C. and Noakes, P. G. (2002). Role of P2X7 receptors in transmitter release in mice. Society for Neuroscience Annual Meeting 2002, Orlando, Florida, 2-7 November, 2002. Washington , DC: Society for Neuroscience.

The motor neurite terminal determines where neuromuscular synapses form in the absence of agrin

Banks, G. B. and Noakes, P. G. (2002). The motor neurite terminal determines where neuromuscular synapses form in the absence of agrin. 14th Biennial Meeting of the International Society for Developmental Neuroscienc, Sydney, 31 January-4 February 2002. Oxford: Pergamon Press. doi: 10.1016/S0736-5748(01)00059-4

Increased motoneuron survival in gephyrin-deficient mice

Banks, G. B., Kneussel, M., Betz, H. and Noakes, P. G. (2001). Increased motoneuron survival in gephyrin-deficient mice. 31st Annual Meeting of the Society for Neuroscience, San Diego, 10-15 November 2001. United States of America: Society for Neuroscience.

Location of the synaptic site in muscle is determined by the innervating motoneuron

Banks, G. B. and Noakes, P. G. (2001). Location of the synaptic site in muscle is determined by the innervating motoneuron. ComBio 2001, National Convention Centre, Canberra, 30 September-4 October 2001. Kent Town, S.A.: Australian Soc. for Biochemistry & Molecular Biology Inc.

Motoneuron cell death, branching and muscle activity in agrin-deficient mice

Noakes, P. G., Banks, G., Choy, P. T., Lavidis, N. A. and Bellingham, M. C. (2001). Motoneuron cell death, branching and muscle activity in agrin-deficient mice. 31st Annual Meeting of the Society for Neuroscience, San Diego, 10-15 November 2001. USA: Society for Neuroscience.

Motoneuron survival is unchanged in b2-laminin deficient mice

Ireland, M. F., Banks, G. B. and Noakes, P. G. (2001). Motoneuron survival is unchanged in b2-laminin deficient mice. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane, 28-31 January 2001. Sydney: Australian Neuroscience Society.

Promotion of motoneuron survival and intramuscular axonal branching in agrin-deficient mice

Banks, G. B. and Noakes, P. G. (2001). Promotion of motoneuron survival and intramuscular axonal branching in agrin-deficient mice. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane, 28-31 January 2001. Sydney: Australian Neuroscience Society.

Suppressor of cytokine signalling-3 is decreased in rapsyn deficient mice

Bartlett, S., Banks, G. B. and Noakes, P. G. (2001). Suppressor of cytokine signalling-3 is decreased in rapsyn deficient mice. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane, 28-31 January 2001. Sydney: Ausrralian Neuroscience Society.

The development of synaptic connections: Genetic analysis in mice

Noakes, P. G. (2001). The development of synaptic connections: Genetic analysis in mice. ComBio 2001, National Convenetion Centre, Canberra, 30 September-4 October 2001. Kent Town, SA: Australian Society for Biochemistry & Molecular Biology.

Agrin is needed to build an organised basal lamina over developing skeletal muscle

Roberston, L. and Noakes, P. G. (2000). Agrin is needed to build an organised basal lamina over developing skeletal muscle. 20th Annual Meeting of the Australian Neuroscience Society, Melbourne, Australia, Jan 30 - Feb 2, 2000.

Altered motoneuron death in rapsyn deficient mice

Banks, G., Bartlett, S. E. and Noakes, P.G. (2000). Altered motoneuron death in rapsyn deficient mice. 20th Annual meeting: Australian Neuroscience Society Annual Conference, Melbourne, Australia, 30 Jan 30 - 2 Feb, 2000. Australian Neuroscience Society.

Functional analysis of beta 2-laminin deficient synapses

Noakes, P. G., Kim, D., Knight, D. and Lavidis, N. A. (2000). Functional analysis of beta 2-laminin deficient synapses. 20th Annual Meeting of the Australian Neuroscience Society, Melbourne, Australia, 30 Jan - 2 Feb, 2000. Australia: Australian Neuroscience Society.

Promotion of motoneuron survival and branching in rapsyn mutant mice

Banks, G., Bartlett, S.E. and Noakes P.G. (2000). Promotion of motoneuron survival and branching in rapsyn mutant mice. Annual Meeting of the Society for Neuroscience, New Orleans, Louisiana, United States, 4-9 November, 2000. Washington, D.C., United States: Society for Neuroscience (SfN).

The regulatory role of neuregulin in acetylcholine receptor clustering at the neuromuscular synapse

Ngo, S. T., Phillips, W. D. and Noakes P. G. (2000). The regulatory role of neuregulin in acetylcholine receptor clustering at the neuromuscular synapse. Society for Neuroscience Annual Meeting 2000, New Orleans, Louisiana, 4-9 November, 2000. Online: Society for Neuroscience.

Altered motor neuron programmed cell death in Rapsyn deficient mice: A role of neurotrophic factors

Banks, G., Bartlett, S. and Noakes, P. G. (1999). Altered motor neuron programmed cell death in Rapsyn deficient mice: A role of neurotrophic factors. ComBio 99, Conrad Jupiters, Gold Coast, Qld., 27-30 September 1999. Kent Town, S.A.: Australian Society for Biochemistry and Molecular Biology.

Analysis of skeletal muscle basal lamina in wild-type and agrin-deficient mice

Robertson, L. N. and Noakes, P. G. (1999). Analysis of skeletal muscle basal lamina in wild-type and agrin-deficient mice. ComBio 99, Conrad Jupiters, Gold Coast, Qld., 27 - 30 September, 1999. Kent Town, S.A.: Australian Society for Biochemistry and Molecular Biology.

Molecular and function changes at the developing beta-2 laminin mutant neuromuscular synapse

Noakes P. G., Bartlett, S. E., Kim, D., Knight, D. and Lavidis, N. A. (1999). Molecular and function changes at the developing beta-2 laminin mutant neuromuscular synapse. Annual Meeting of the Society for Neuroscience, Miami Beach, Florida, USA, 23-28 October, 1999. Bethesda, MD: Society for Neuroscience.

The Role of Neurotrophins at Developing Synapses of b2-Laminin Mutant Mice

Bartlett, S. and Noakes, P. G. (1999). The Role of Neurotrophins at Developing Synapses of b2-Laminin Mutant Mice. 17th Biennial Meeting of the International Society for Neurochemists, Berlin, Germany, 8 -14 Aug1999. USA: Lippiniott Williams & Wilkins.

Development of the neuromuscular junction: Genetic analysis in mice

Sanes, Joshua R., Apel, Elizabeth D., Burgess, Robert W., Emerson, Ronald B., Feng, Guoping, Gautam, Medha, Glass, David, Grady, R. Mark, Krejci, Eric, Lichtman, Jeff W., Lu, Jonathan T., Massoulié, Jean, Miner, Jeffrey H., Moscoso, Lisa M., Nguyen, Quyen, Nichol, Mia, Noakes, Peter G., Patton, Bruce L., Son, Young-Jin, Yancopoulos, George D. and Zhou, Heather (1998). Development of the neuromuscular junction: Genetic analysis in mice. Elsevier Masson SAS. doi: 10.1016/S0928-4257(98)80004-1