The University of Queensland

Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma

Cruz, Jazmina L. and Wells, James W. (2016). Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma. Horizons in cancer research. (pp. 119-145) edited by Hiroto S. Watanabe. New York, United States: Nova Science Publishers.

Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?

Wells, James W. (2015). Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?. Actinic keratosis. (pp. 36-41) edited by H. Peter Soyer, Tarl W. Prow and Gregor B. E. Jemec. Basel, Switzerland: Karger AG. doi: 10.1159/000366533

Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts

Veitch, Margaret, Beaumont, Kimberly, Pouwer, Rebecca, Chew, Hui Yi, Frazer, Ian H, Soyer, H Peter, Campbell, Scott, Dymock, Brian W, Harvey, Andrew, Cock, Terrie-Anne and Wells, James W (2023). Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts. Journal for ImmunoTherapy of Cancer, 11 (9), e006783. doi: 10.1136/jitc-2023-006783

Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer

Firdaus, Farrhana Z., Bartlett, Stacey, Hussein, Waleed M., Lu, Lantian, Wright, Quentin, Huang, Wenbin, Nahar, Ummey J., Yang, Jieru, Khongkow, Mattaka, Veitch, Margaret, Koirala, Prashamsa, Ruktanonchai, Uracha R., Monteiro, Michael J., Gonzalez Cruz, Jazmina L., Stephenson, Rachel J., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2023). Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer. Pharmaceutics, 15 (2) 602, 1-15. doi: 10.3390/pharmaceutics15020602

Cytokine/Chemokine assessment as a complementary diagnostic tool for inflammatory skin diseases

Liu, Timothy J., Lin, Lynlee L., McMeniman, Erin, Wu, Jason, Kao, Yung-Ching, Kumari, Snehlata, Boyle, Glen M., Wells, James W., Soyer, H. Peter and Gonzalez-Cruz, Jazmina L. (2022). Cytokine/Chemokine assessment as a complementary diagnostic tool for inflammatory skin diseases. Frontiers in Immunology, 13 1028435, 1-8. doi: 10.3389/fimmu.2022.1028435

Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability

Veitch, Margaret, Layt, Craig, Raymond, Emma, Croaker, Andrew and Wells, James (2022). Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability. Archives of Medical Science, 18 (6), 1683-1688. doi: 10.5114/aoms/155183

Prevalence of AAV2.5 neutralizing antibodies in synovial fluid and serum of patients with osteoarthritis

Abdul, Temilola Y., Hawse, Gresin P., Smith, Jay, Sellon, Jacob L., Abdel, Matthew P., Wells, James W., Coenen, Michael J., Evans, Christopher H. and De La Vega, Rodolfo E. (2022). Prevalence of AAV2.5 neutralizing antibodies in synovial fluid and serum of patients with osteoarthritis. Gene Therapy, 30 (7-8), 1-5. doi: 10.1038/s41434-022-00326-5

Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial

Depelsenaire, Alexandra C. I., Witham, Katey, Veitch, Margaret, Wells, James W., Anderson, Christopher D., Lickliter, Jason D., Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian, Fernando, Germain J. P. and Forster, Angus H. (2021). Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial. PLoS One, 16 (7) e0255282, e0255282. doi: 10.1371/journal.pone.0255282

Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression

Proctor, Martina, Gonzalez Cruz, Jazmina L., Daignault-Mill, Sheena M., Veitch, Margaret, Zeng, Bijun, Ehmann, Anna, Sabdia, Muhammed, Snell, Cameron, Keane, Colm, Dolcetti, Riccardo, Haass, Nikolas K., Wells, James W. and Gabrielli, Brian (2021). Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression. Cancers, 13 (15) 3733, 1-19. doi: 10.3390/cancers13153733

PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapy

Wright, Quentin, Gonzalez Cruz, Jazmina L., Wells, James W. and Leggatt, Graham R. (2021). PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapy. Cancers, 13 (13) 3310, 3310. doi: 10.3390/cancers13133310

Evolution of cancer vaccines—challenges, achievements and future directions

Tay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535

IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression

Zeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131

Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1

Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22

Investigating T cell immunity in cancer: achievements and prospects

Zeng, Zhen, Chew, Hui Yi, Cruz, Jazmina G., Leggatt, Graham R. and Wells, James W. (2021). Investigating T cell immunity in cancer: achievements and prospects. International Journal of Molecular Sciences, 22 (6) 2907, 1-17. doi: 10.3390/ijms22062907

Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy

Chandra, Janin, Teoh, Siok Min, Kuo, Paula, Tolley, Lynn, Bashaw, Abate Assefa, Tuong, Zewen Kelvin, Liu, Yang, Chen, Zibin, Wells, James W., Yu, Chengzhong, Frazer, Ian H. and Yu, Meihua (2021). Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy. The Journal of Immunology, 206 (5), ji2000355-998. doi: 10.4049/jimmunol.2000355

Peripheral tolerance checkpoints imposed by ubiquitous antigen expression limit antigen-specific B cell responses under strongly immunogenic conditions

Brooks, Jeremy F., Murphy, Peter R., Barber, James E. M., Wells, James W. and Steptoe, Raymond J. (2020). Peripheral tolerance checkpoints imposed by ubiquitous antigen expression limit antigen-specific B cell responses under strongly immunogenic conditions. The Journal of Immunology, 205 (5), ji2000377-1247. doi: 10.4049/jimmunol.2000377

Safety, tolerability and immunogenicity of influenza vaccination with a high-density microarray patch: results from a randomized, controlled phase I clinical trial

Forster, Angus H, Witham, Katey, Depelsenaire, Alexandra C.I., Veitch, Margaret, Wells, James W., Wheatley, Adam, Pryor, Melinda, Lickliter, Jason, Francis, Barbara, Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian and Fernando, Germain J.P. (2020). Safety, tolerability and immunogenicity of influenza vaccination with a high-density microarray patch: results from a randomized, controlled phase I clinical trial. PLoS Medicine, 17 (3) e1003024, e1003024. doi: 10.1371/journal.pmed.1003024

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285

Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production

Brooks, Jeremy F., Barber, James E.M., Davies, Janet M., Wells, James W. and Steptoe, Raymond J. (2020). Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production. Cytotherapy, 22 (8), 436-444. doi: 10.1016/j.jcyt.2020.04.041

Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage

Tuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0

Editorial: Insights into biomarkers, cytokines, and chemokines in skin cancer

Barrett, Lucy W., Gray, Elin S., Wells, James W. and Waithman, Jason (2019). Editorial: Insights into biomarkers, cytokines, and chemokines in skin cancer. Frontiers in Medicine, 6 199, 199. doi: 10.3389/fmed.2019.00199

Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma

Crawford, Theo, Fletcher, Nicholas, Veitch, Margaret, Gonzalez Cruz, Jazmina L., Pett, Nicola, Brereton, Ian, Wells, James W., Mobli, Mehdi and Tesiram, Yasvir (2019). Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 6 (FEB) 22, 22. doi: 10.3389/fmed.2019.00022

Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer

Khongkow, Mattaka, Liu, Tzu-yu, Bartlett, Stacey, Hussein, Waleed M., Nevagi, Reshma, Jia, Zhongfan, Monteiro, Michael J., Wells, James, Ruktanonchai, Uracha Rungsardthong, Skwarczynski, Mariusz and Toth, Istvan (2018). Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Precision Nanomedicine, 1 (3), 183-193. doi: 10.33218/prnano1(3).181003.1

Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer

Bridge, Jennifer A., Lee, James C., Daud, Adil, Wells, James W. and Bluestone, Jeffrey A. (2018). Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer. Frontiers in Medicine, 5 (DEC) 351, 351. doi: 10.3389/fmed.2018.00351

The role of CXCR3 and its chemokine ligands in skin disease and cancer

Kuo, Paula T., Zeng, Zhen, Salim, Nazhifah, Mattarollo, Stephen, Wells, James W. and Leggatt, Graham R. (2018). The role of CXCR3 and its chemokine ligands in skin disease and cancer. Frontiers in Medicine, 5 (SEP) 271, 271. doi: 10.3389/fmed.2018.00271

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

Jung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018). Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology, 7 (9) e1479627, 1-16. doi: 10.1080/2162402X.2018.1479627

Tetramer-based identification of naïve antigen-specific B cells within a polyclonal repertoire

Brooks, Jeremy F., Liu, Xiao, Davies, Janet M., Wells, James W. and Steptoe, Raymond J. (2018). Tetramer-based identification of naïve antigen-specific B cells within a polyclonal repertoire. European Journal of Immunology, 48 (7), 1251-1254. doi: 10.1002/eji.201747447

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

He, Xuzhi, Cruz, Jazmina L., Joseph, Shannon, Pett, Nicola, Chew, Hui Yi, Tuong, Zewen K., Okano, Satomi, Kelly, Gabrielle, Veitch, Margaret, Simpson, Fiona and Wells, James W. (2018). Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Oncotarget, 9 (15), 12250-12260. doi: 10.18632/oncotarget.24242

Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy

Brooks, Jeremy F, Davies, Janet M, Wells, James W and Steptoe, Raymond J (2017). Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy. Journal of Molecular Medicine (Berlin, Germany), 96 (1), 21-30. doi: 10.1007/s00109-017-1611-8

CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin

Overgaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R

Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma

Keller, Hilary R., Zhang, Xin, Li, Li, Schaider, Helmut and Wells, James W. (2017). Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma. Oncotarget, 8 (43), 75675-75686. doi: 10.18632/oncotarget.18523

Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipients

Burke, Michael Thomas, Sambira Nahum, Lauren C., Isbel, Nicole M., Carroll, Robert P., Soyer, Hans Peter, Francis, Ross, Bridge, Jennifer Anne, Hawley, Carmel, Oliver, Kimberly, Staatz, Christine E. and Wells, James William (2017). Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipients. Transplantation Direct, 3 (7), e171. doi: 10.1097/TXD.0000000000000694

Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance

Bhatt, Kunal H., Rudraraju, Rajeev, Brooks, Jeremy F., Jung, Ji-Won, Galea, Ryan, Wells, James W. and Steptoe, Raymond J. (2017). Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance. Stem Cell Research and Therapy, 8 (1) 57, 57. doi: 10.1186/s13287-017-0508-3

DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection

Chandra, Janin, Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K., Yong, Michelle, Wells, James W., Leggatt, Graham R., Finlayson, Neil and Frazer, Ian H. (2017). DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection. Journal of Immunotherapy, 40 (2), 62-70. doi: 10.1097/CJI.0000000000000156

Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femur

Liu, Fangjun, Wells, James W., Porter, Ryan M., Glatt, Vaida, Shen, Zhenxin, Schinhan, Martina, Ivkovic, Alan, Vrahas, Mark S., Evans, Christopher H. and Ferreira, Elisabeth (2016). Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femur. Journal of Orthopaedic Research, 34 (12), 2137-2145. doi: 10.1002/jor.23255

Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow

Cruz, Jazmina L. and Wells, James W. (2016). Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow. Experimental Dermatology, 25 (7), 507-508. doi: 10.1111/exd.13041

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines

Hussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

Moyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049

Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle

Liu, F., Ferreira, E., Porter, R. M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M. A., Kirker-Head, C. A., Wehling, C., Vrahas, M. S., Evans, C. H. and Wells, J. W. (2015). Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle. European Cells and Materials, 30 (30), 118-131. doi: 10.22203/eCM.v030a09

Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?

Roufaiel, Marian Nassef Kadry Naguib, Wells, James W. and Steptoe, Raymond J. (2015). Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?. Frontiers in Immunology, 6 (JUN) 258, 258.1-258.10. doi: 10.3389/fimmu.2015.00258

A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells

Collin, Joseph F., Wells, James W., Czepulkowski, Barbara, Lyne, Linden, Duriez, Patrick J., Banham, Alison H., Mufti, Ghulam J. and Guinn, Barbara-ann (2015). A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells. Genes Chromosomes Cancer, 54 (5), 288-302. doi: 10.1002/gcc.22242

Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?

Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450

HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions

Bergot, Anne-Sophie, Monnet, Nastasia, Tran, Son Le, Mittal, Deepak, Al-Kouba, Jane, Steptoe, Raymond J., Grimbaldeston, Michele A., Frazer, Ian H. and Wells, James W. (2015). HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunology and Cell Biology, 93 (6), 540-547. doi: 10.1038/icb.2014.123

CD4+/CD8+ double positive T cells: more than just a developmental stage?

Overgaard, Nana H., Jung, Ji-Won, Steptoe, Raymond J. and Wells, James W. (2015). CD4+/CD8+ double positive T cells: more than just a developmental stage?. Journal of Leukocyte Biology, 97 (1), 31-38. doi: 10.1189/jlb.1RU0814-382

Genetics and nonmelanoma skin cancer in kidney transplant recipients

Burke, Michael T., Isbel, Nicole, Barraclough, Katherine A., Jung, Ji-Won, Wells, James W. and Staatz, Christine E. (2015). Genetics and nonmelanoma skin cancer in kidney transplant recipients. Pharmacogenomics, 16 (2), 161-172. doi: 10.2217/pgs.14.156

Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage

Freeman, Andrew, Bridge, Jennifer A., Maruthayanar, Pirashanthini, Overgaard, Nana H., Jung, Ji-Won, Simpson, Fiona, Prow, Tarl W., Soyer, H. Peter, Frazer, Ian H., Freeman, Michael and Wells, James W. (2014). Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage. PLoS One, 9 (10) e110928, e110928.1-e110928.9. doi: 10.1371/journal.pone.0110928

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

Bergot, Anne-Sophie, Ford, Neill, Leggatt, Graham R., Wells, James W., Frazer, Ian H. and Grimbaldeston, Michele A. (2014). HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells. PLoS Pathogens, 10 (10), 1-11. doi: 10.1371/journal.ppat.1004466

Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow

Ferreira, Elisabeth, Porter, Ryan M., Wehling, Nathalie, O'Sullivan, Regina P., Liu, Fangjun, Boskey, Adele, Estok, Daniel M., Harris, Mitchell B., Vrahas, Mark S., Evans, Christopher H. and Wells, James W. (2013). Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry, 288 (41), 29494-29505. doi: 10.1074/jbc.M113.471268

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100

Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation

Wells, James W., Evans, Christopher H., Scott, Milcah C., Ruetgen, Barbara C., O'Brien, Timothy D., Modiano, Jaime F., Cvetkovic, Goran and Tepic, Slobodan (2013). Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation. PLoS One, 8 (1) e54464, e54464.1-e54464.9. doi: 10.1371/journal.pone.0054464

EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing Sarcoma Family of Tumors

Evans, Christopher H., Liu, Fangjun, Porter, Ryan M., O'Sullivan, Regina P., Merghoub, Taha, Lunsford, Elaine P., Robichaud, Kyle, Van Valen, Frans, Lessnick, Stephen L., Gebhardt, Mark C. and Wells, James W. (2012). EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing Sarcoma Family of Tumors. Clinical Cancer Research, 18 (19), 5341-5351. doi: 10.1158/1078-0432.CCR-12-1985

Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.

Liu, Fangjun, Porter, Ryan M., Wells, James, Glatt, Vaida, Pilapil, Carmencita and Evans, Christopher H. (2011). Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.. Journal of Orthopaedic Research, 30 (7), 1095-1102. doi: 10.1002/jor.22038

Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage

Evans, C.H., Liu, F.-J., Glatt, V., Hoyland, J. A., Kirker-Head, C., Walsh, A., Betz, O., Wells, J. W., Betz, V., Porter, R. M., Saad, F. A., Gerstenfeld, L. C., Einhorn, T. A., Harris, M. B. and Vrahas, M. S. (2009). Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. European Cells and Materials, 18, 96-111.

Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways

Wehling, N., Palmer, G. D., Pilapil, C., Liu, F., Wells, J. W., Muller, P. E., Evans, C. H. and Porter, R. M. (2009). Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways. Arthritis and Rheumatism, 60 (3), 801-812. doi: 10.1002/art.24352

Suppression of airway inflammation by a natural acute infection of the intestinal epithelium

Gibbons, D. L., Haque, S. F. Y., Copestake, S. L., Wells, J. W. and Hayday, A. C. (2009). Suppression of airway inflammation by a natural acute infection of the intestinal epithelium. Mucosal Immunology, 2 (2), 144-155. doi: 10.1038/mi.2008.83

Anti-tumor immunity in a model of acute myeloid leukemia

Cheuk, Adam T. C., Wells, James W., Chan, Lucas, Westwood, Nigel B., Berger, Stuart A., Yagita, Hideo, Okumura, Ko, Farzaneh, Farzin, Mufti, Ghulam J. and Guinn, Barbara-Ann (2009). Anti-tumor immunity in a model of acute myeloid leukemia. Leukemia and Lymphoma, 50 (3), 447-454. doi: 10.1080/10428190802653776

Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine

Wells, J. W., Choy, K., Lloyd, C. M. and Noble, A. (2009). Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine. Mucosal Immunology, 2 (1), 54-62. doi: 10.1038/mi.2008.69

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization

Leggat, Jamie A., Gibbons, Deena L., Haque, Syeda F. Y., Smith, Adrian L., Wells, James W., Choy, Katherine, Lloyd, Clare M., Hayday, Adrian C. and Noble, Alistair (2008). Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization. Journal of Allergy and Clinical Immunology, 122 (5), 1014-1021. doi: 10.1016/j.jaci.2008.08.011

Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity

Wells, J. W., Cowled, C. J., Farzaneh, F. and Noble, A. (2008). Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. Journal of Immunology, 181 (5), 3422-3431. doi: 10.4049/jimmunol.181.5.3422

Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity

Wells, James W., Cowled, Chris J., Darling, David, Guinn, Barbara-Ann, Farzaneh, Farzin, Noble, Alistair and Galea-Lauri, Joanna (2007). Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity. Cancer Immunology Immunotherapy, 56 (12), 1861-1873. doi: 10.1007/s00262-007-0328-x

Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration

Wells, James W., Cowled, Christopher J., Giorgini, Angela, Kemeny, David M. and Noble, Alistair (2007). Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration. Journal of Allergy and Clinical Immunology, 119 (1), 226-234. doi: 10.1016/j.jaci.2006.09.004

Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia

Guinn, Barbara-ann, Bland, Elizabeth A., Lodi, Usman, Liggins, Amanda P., Tobal, Khalid, Petters, Sarah, Wells, James W., Banham, Alison H. and Mufti, Ghulam J. (2005). Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. Biochemical and Biophysical Research Communications, 335 (4), 1293-1304. doi: 10.1016/j.bbrc.2005.08.024

Influence of interleukin-4 on the phenotype and function of bone marrow-derived murine dendritic cells generated under serum-free conditions

Wells, J. W., Darling, D., Farzaneh, F. and Galea-Lauri, J. (2005). Influence of interleukin-4 on the phenotype and function of bone marrow-derived murine dendritic cells generated under serum-free conditions. Scandinavian Journal of Immunology, 61 (3), 251-259. doi: 10.1111/j.1365-3083.2005.01556.x

Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination

Galea-Lauri, Joanna, Wells, James W., Darling, David, Harrison, Phillip and Farzaneh, Farzin (2004). Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination. Cancer Immunology Immunotherapy, 53 (11), 963-977. doi: 10.1007/s00262-004-0542-8

Antigen-encoding bone marrow deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production

Steptoe, R. J., Brooks, J. F. and Wells, J. W. (2019). Antigen-encoding bone marrow deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production. ESGCT 27th Annual Congress in collaboration with SETGyc Meeting, Barcelona Spain, 22-25 October 2019 . New Rochelle, NY, United States: Mary Anne Liebert.

The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma

Zeng, Z., Cruz, J. G., Pett, N., Veitch, M., Frazer, I. H. and Wells, J. W. (2019). The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma. 17th International Congress of Immunology (IUIS), Beijing, Peoples R China, 19-23 October 2019. Weinheim, Germany: Wiley.

Dendritic cell-targeted self-antigen restrains autoreactive B cells by deletion and anergy

Brooks, J., Davies, J., Wells, J. and Steptoe, R. (2018). Dendritic cell-targeted self-antigen restrains autoreactive B cells by deletion and anergy. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018 . Weinheim, Germany: Wiley.

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

He, Xuzhi, Gonzalez Cruz, Jazmina , Simpson, Finoa and Wells, James (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia, 7-9 November 2016. Hoboken, NJ, United States: Wiley-Blackwell.

Effects of Immunosuppression and Sun Exposure on Immune Cell Populations in Skin and Blood of Kidney Transplant Recipients.

Burke, M., Nahum, L., Isbel, N., Carroll, R., Soyer, H., Francis, R., Bridge, J., Staatz, C. and Wells, J. (2016). Effects of Immunosuppression and Sun Exposure on Immune Cell Populations in Skin and Blood of Kidney Transplant Recipients.. American Transplant Congress, Boston Ma, Jun 11-15, 2016. HOBOKEN: WILEY-BLACKWELL.

Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions

Steptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancers

Bridge, Jennifer A., Overgaard, Nana H., Steptoe, Raymond J., Frazer, Ian H. and Wells, James W. (2016). Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancers. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, La, United States, Apr 16-20, 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3999

CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin

Cruz, Gonzalez J. L., Overgaard, N. H., Bridge, J. A., Jung, J. -W, He, J., Nel, H. J., Watson, K., Frazer, I. H., La Gruta, N. L., Steptoe, R. J. and Wells, J. W. (2016). CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?

Brooks, J., Al-Kouba, J., Davies, J., Wells, J. and Steptoe, R. (2016). Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Immunotherapy for persisting viral infection and associated cancer

Frazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers

Mattarollo, Stephen, Leggatt, Graham, Wells, James, Lambert, Paul and Frazer, Ian H. (2016). Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-A064

Novel regulators of CD8 T-cell functions in the skin

Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L. G., Veitch, Margaret, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2016). Novel regulators of CD8 T-cell functions in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular and Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia , November 7–9, 2016. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/wrr.12489

Novel regulators of CD8(+) T-cell functions in the skin

Bridge, J. A., Overgaard, N. H., Cruz, J. L. G., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Novel regulators of CD8(+) T-cell functions in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-16 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

He, X., Cruz, Gonzalez J., Simpson, F. and Wells, J. (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skin

Jung, Ji-Won, Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne Exhibition and Convention Centre, Melbourne, Australia, 7-9 November 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma

Jung, Ji-Won, Taylor, Paul J., Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-B055

Uncovering novel regulators of CD8(+) T-cell functions in the skin

Bridge, J. A., Overgaard, N. H., Cruz, J. L., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Uncovering novel regulators of CD8(+) T-cell functions in the skin. Asia-Pacific Combined Dermatology Research Conference, Noosa, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/ajd.12584

Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells

Ferreira, Elisabeth, Wells, James W. and Evans, Christopher H. (2010). Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells. 16th International Conference of the Inflammation-Research-Association, Chantilly Va, 2008. BIRKHAUSER VERLAG AG.

Immune Gene Therapy for Acute Myeloid Leukaemia

Farzaneh, Farzin, Chan, Lucas, Hardwick, Nicola, Ingram, Wendy, Mufti, Ghulam, Aloysius, Mark, Robins, Adrian, Habib, Nagy, Bhalla, Joti, Eremin, Oleg, Jun, Tye Gee, Oppenheim, David, Wells, James, Cowled, Christopher and Noble, Alistair (2010). Immune Gene Therapy for Acute Myeloid Leukaemia. 17th Annual Meeting of German-Society-for-Gene-Therapy (DG-GT e.V.), Munich, Germany, 7 - 9 October 2010. New Rochelle, NY United States: Mary Ann Liebert, Inc. Publishers.

Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator

Porter, R. M., Ivkovic, A., Wells, J., Glatt, V., Harris, M. B., Vrahas, M. S. and Evans, C. (2008). Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Expedited strategies for the restoration of bone

Evans, C. H., Glatt, V., Liu, F.-J., Wells, J. W., Ferreira, E., Vrahas, M. S., Harris, M. B., Ivkovic, A. and Porter, R. M. (2008). Expedited strategies for the restoration of bone. The Second International Symposium on Biotechnology in Musculoskeletal Repair, Lausanne, Switzerland, 2-4 October, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Improving the osteogenic behaviour of human mesenchymal stromal cells

Ivkovic, A., Porter, R. M., Wells, J. W. and Evans, C. H. (2008). Improving the osteogenic behaviour of human mesenchymal stromal cells. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways

Porter, R. M., Wehling, N., Palmer, G. D., Wells, J. W., Muller, P. E. and Evans, C. H. (2008). Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Local cross-presentation of allergen to CD8 cells by lung dendritic cells regulates allergic airways inflammation

Wells, JW, Cowled, CJ, Giorgini, A, Noble, A and Kemeny, DM (2005). Local cross-presentation of allergen to CD8 cells by lung dendritic cells regulates allergic airways inflammation. BLACKWELL PUBLISHING.

HCV core protein interferes with mhc class irestricted antigen processing/presentation by murine dendritic cells

O'Beirne, JP, Cross, T, Wells, J, Farzaneh, F and Harrison, PM (2005). HCV core protein interferes with mhc class irestricted antigen processing/presentation by murine dendritic cells. 40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Paris France, Apr 13-17, 2005. ELSEVIER SCIENCE BV.

Effect of HCV core protein on the ability of murine dendritic cells to generate a MHC class I-restricted antigen-specific immune response, in vitro.

O'Beirne, JP, Mitchell, J, Wells, J, Farzaneh, F and Harrison, PM (2004). Effect of HCV core protein on the ability of murine dendritic cells to generate a MHC class I-restricted antigen-specific immune response, in vitro.. 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Oct 29-Nov 02, 2004. JOHN WILEY & SONS INC.

Compound for prevention or treatment of a skin cancer or skin precancer

Wells, James, Dymock, Brian William, Harvey, Andrew, Cock, Terrie-Anne, Pouwer, Rebecca and Beaumont, Kimberley (2021). Compound for prevention or treatment of a skin cancer or skin precancer. WO2021248189.

Composition comprising a cytotoxic t-cell - inducing adjuvant

Wells, James William and Noble, Alistair (2008). Composition comprising a cytotoxic t-cell - inducing adjuvant. WO2007122392-A8.