The University of Queensland

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

Wells, Timothy J., Davison, John, Sheehan, Emma, Kanagasundaram, Suren, Spickett, Gavin, MacLennan, Calman A., Stockley, Robert A., Cunningham, Adam F., Henderson, Ian R. and De Soyza, Anthony (2017). The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies. American Journal of Respiratory and Critical Care Medicine, 195 (7), 955-958. doi: 10.1164/rccm.201603-0599LE

Type 1 and 5 secretion systems and associated toxins

Wells, Timothy J. and Henderson, Ian R. (2013). Type 1 and 5 secretion systems and associated toxins. Escherichia coli: pathotypes and principles of pathogenesis. (pp. 499-532) edited by Michael S. Donnenberg. Cambridge, MA, United States: Academic Press. doi: 10.1016/B978-0-12-397048-0.00016-4

Impact of CFTR Modulation on <i>Pseudomonas aeruginosa</i> Infection in People With Cystic Fibrosis

Ledger, Emma L, Smith, Daniel J, Teh, Jing Jie, Wood, Michelle E, Whibley, Page E, Morrison, Mark, Goldberg, Joanna B, Reid, David W and Wells, Timothy J (2024). Impact of CFTR Modulation on Pseudomonas aeruginosa Infection in People With Cystic Fibrosis. The Journal of Infectious Diseases. doi: 10.1093/infdis/jiae051

Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections

Hickson, Sarah M., Hoehensteiger, Johannes K., Mayer-Coverdale, Johanna, Torres, Von Vergel L., Feng, Wenkang, Monteith, Joshua N., Henderson, Ian R., McCarthy, Kate L. and Wells, Timothy J. (2024). Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections. The Journal of Infectious Diseases. doi: 10.1093/infdis/jiad457

Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades

Pham, Amy, Volmer, James G., Chambers, Daniel C., Smith, Daniel J., Reid, David W., Burr, Lucy and Wells, Timothy J. (2023). Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades. Frontiers in Microbiology, 14 1274280, 1-14. doi: 10.3389/fmicb.2023.1274280

Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2

McCulloch, Timothy R., Rossi, Gustavo Rodrigues, Lam, Allie, Wong, Joshua, Kane, Lawrence P, Herold, Marco, Wells, Timothy and Souza-Fonseca-Guimaraes, Fernando (2023). Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2. The Journal of Immunology, 210 (S1), 72.28-72.28. doi: 10.4049/jimmunol.210.supp.72.28

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection

McCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516

Genomic diversity and antimicrobial resistance of Prevotella species isolated from chronic lung disease airways

Webb, Kasey A., Olagoke, Olusola, Baird, Timothy, Neill, Jane, Pham, Amy, Wells, Timothy J., Ramsay, Kay A., Bell, Scott C., Sarovich, Derek S. and Price, Erin P. (2022). Genomic diversity and antimicrobial resistance of Prevotella species isolated from chronic lung disease airways. Microbial Genomics, 8 (2) 000754. doi: 10.1099/mgen.0.000754

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

Tran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166

Inferior outcomes in lung transplant recipients with serum Pseudomonas aeruginosa specific cloaking antibodies

Divithotawela, Chandima, Pham, Amy, Bell, Peter T., Ledger, Emma L., Tan, Maxine, Yerkovich, Stephanie, Grant, Michelle, Hopkins, Peter M., Wells, Timothy J. and Chambers, Daniel C. (2021). Inferior outcomes in lung transplant recipients with serum Pseudomonas aeruginosa specific cloaking antibodies. The Journal of Heart and Lung Transplantation, 40 (9), 951-959. doi: 10.1016/j.healun.2021.05.016

Anti-LPS IgA and IgG can inhibit serum killing of Pseudomonas aeruginosa in patients with cystic fibrosis

Pham, Amy, Ledger, Emma L., Coggon, Carrie F., Henderson, Ian R., Reid, David W., Bell, Scott C., Smith, Daniel J. and Wells, Timothy J. (2021). Anti-LPS IgA and IgG can inhibit serum killing of Pseudomonas aeruginosa in patients with cystic fibrosis. Infection and Immunity, 89 (12) e00412-21, e0041221. doi: 10.1128/iai.00412-21

Towards efficient immunotherapy for bacterial infection

McCulloch, Timothy R., Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2021). Towards efficient immunotherapy for bacterial infection. Trends in Microbiology, 30 (2), 158-169. doi: 10.1016/j.tim.2021.05.005

Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice

Romand, Xavier, Liu, Xiao, Rahman, M. Arifur, Bhuyan, Zaied Ahmed, Douillard, Claire, Arora Kedia, Reena, Stone, Nathan, Roest, Dominique, Chew, Zi Huai, Cameron, Amy J., Rehaume, Linda M., Bozon, Aurélie, Habib, Mohammed, Armitage, Charles W., Nguyen, Minh Vu Chuong, Favier, Bertrand, Beagley, Kenneth, Maurin, Max, Gaudin, Philippe, Thomas, Ranjeny, Wells, Timothy J. and Baillet, Athan (2021). Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice. Arthritis and Rheumatology, 73 (7) art.41653, 1200-1210. doi: 10.1002/art.41653

BamA and BamD are essential for the secretion of trimeric autotransporter adhesins

Rooke, Jessica L., Icke, Christopher, Wells, Timothy J, Rossiter, Amanda E., Browning, Douglas F., Morris, Faye C., Leo, Jack C., Schütz, Monika S., Autenrieth, Ingo B., Cunningham, Adam F., Linke, Dirk and Henderson, Ian R. (2021). BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Frontiers in Microbiology, 12 628879, 1-10. doi: 10.3389/fmicb.2021.628879

Antibody-dependent enhancement of bacterial disease: prevalence, mechanisms and treatment

Torres, Von Vergel L., Coggon, Carrie F. and Wells, Timothy J. (2021). Antibody-dependent enhancement of bacterial disease: prevalence, mechanisms and treatment. Infection and Immunity, 89 (4) e00054-21, 1-15. doi: 10.1128/IAI.00054-21

Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice

Moentadj, Rabia, Wang, Yiwen, Bowerman, Kate, Rehaume, Linda, Nel, Hendrik, O Cuiv, Paraic, Stephens, Juliette, Baharom, Amalina, Maradana, Muralidhara, Lakis, Vanessa, Morrison, Mark, Wells, Timothy, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2021). Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice. Annals of the Rheumatic Diseases, 80 (5) annrheumdis-2020-219009, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219009

Structure of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localization

Bryant, Jack Alfred, Morris, Faye C., Knowles, Timothy J., Maderbocus, Riyaz, Heinz, Eva, Boelter, Gabriela, Alodaini, Dema, Colyer, Adam, Wotherspoon, Peter J., Staunton, Kara A., Jeeves, Mark, Browning, Douglas F., Sevastsyanovich, Yanina R., Wells, Timothy J., Rossiter, Amanda E., Bavro, Vassiliy N., Sridhar, Pooja, Ward, Douglas G., Chong, Zhi-Soon, Goodall, Emily C. A., Icke, Christopher, Teo, Alvin, Chng, Shu-Sin, Roper, David I., Lithgow, Trevor, Cunningham, Adam F., Banzhaf, Manuel, Overduin, Michael and Henderson, Ian R. (2020). Structure of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localization. eLife, 9 e62614, 1-61. doi: 10.7554/elife.62614

Treatment of life-threatening Pseudomonas aeruginosa infection by pheresis of inhibitory antibodies

Divithotawela, Chandima, Pham, Amy, Ledger, Emma L., Hopkins, Peter, Wells, Timothy J. and Chambers, Daniel (2020). Treatment of life-threatening Pseudomonas aeruginosa infection by pheresis of inhibitory antibodies. Journal of Heart and Lung Transplantation, 39 (1), 87-89. doi: 10.1016/j.healun.2019.10.001

Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway

Benedikz, Elizabeth K., Bailey, Dalan, Cook, Charlotte N. L., Gonçalves-Carneiro, Daniel, Buckner, Michelle M. C., Blair, Jessica M. A., Wells, Timothy J., Fletcher, Nicola F., Goodall, Margaret, Flores-Langarica, Adriana, Kingsley, Robert A., Madsen, Jens, Teeling, Jessica, Johnston, Sebastian L., MacLennan, Calman A., Balfe, Peter, Henderson, Ian R., Piddock, Laura J. V., Cunningham, Adam F. and McKeating, Jane A. (2019). Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway. Scientific Reports, 9 (1) 7903. doi: 10.1038/s41598-019-44263-7

YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium

Morris, Faye C., Wells, Timothy J., Bryant, Jack A., Schager, Anna E., Sevastsyanovich, Yanina R., Squire, Derrick J. P., Marshall, Jennifer, Isom, Georgia L., Rooke, Jessica, Maderbocus, Riyaz, Knowles, Timothy J., Overduin, Michael, Rossiter, Amanda E., Cunningham, Adam F. and Henderson, Ian R. (2018). YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium. Infection and Immunity, 86 (11) e00829-17. doi: 10.1128/IAI.00829-17

A novel method of serum resistance by Escherichia coli that causes urosepsis

Coggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella

Hammarlof, Disa L., Kroger, Carsten, Owen, Sian V., Canals, Rocio, Lacharme-Lora, Lizeth, Wenner, Nicolas, Schager, Anna E., Wells, Timothy J., Henderson, Ian R., Wigley, Paul, Hokamp, Karsten, Feasey, Nicholas A., Gordon, Melita A. and Hinton, Jay C. D. (2018). Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. Proceedings of the National Academy of Sciences of the United States of America, 115 (11), E2614-E2623. doi: 10.1073/pnas.1714718115

Antigen localization influences the magnitude and kinetics of endogenous adaptive immune response to recombinant Salmonella vaccines

Sevastsyanovich, Yanina R., Withers, David R., Marriott, Claire L., Morris, Faye C., Wells, Timothy J., Browning, Douglas F., Beriotto, Irene, Ross, Ewan, Ali, Hossam Omar, Wardius, Catherine A., Cunningham, Adam F., Henderson, Ian R. and Rossiter, Amanda E. (2017). Antigen localization influences the magnitude and kinetics of endogenous adaptive immune response to recombinant Salmonella vaccines. Infection and Immunity, 85 (12) e00593-17, e00593-17. doi: 10.1128/iai.00593-17

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

Wells, Timothy J., Davison, John, Sheehan, Emma, Kanagasundaram, Suren, Spickett, Gavin, MacLennan, Calman A., Stockley, Robert A., Cunningham, Adam F., Henderson, Ian R. and De Soyza, Anthony (2017). The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies. American Journal of Respiratory and Critical Care Medicine, 195 (7), 955-958. doi: 10.1164/rccm.201603-0599LE

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion

Browning, Douglas F., Bavro, Vassiliy N., Mason, Jessica L., Sevastsyanovich, Yanina R., Rossiter, Amanda E., Jeeves, Mark, Wells, Timothy J., Knowles, Timothy J., Cunningham, Adam F., Donald, James W., Palmer, Tracy, Overduin, Michael and Henderson, Ian R. (2015). Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion. Molecular Microbiology, 97 (4), 646-659. doi: 10.1111/mmi.13052

Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing

Wells, Timothy J., Whitters, Deborah, Sevastsyanovich, Yanina R., Heath, Jennifer N., Pravin, John, Goodall, Margaret, Browning, Douglas F., O'Shea, Matthew K., Cranston, Amy, De Soyza, Anthony, Cunningham, Adam F., MacLennan, Calman A., Henderson, Ian R. and Stockley, Robert A. (2014). Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing. Journal of Experimental Medicine, 211 (9), 1893-1904. doi: 10.1084/jem.20132444

Mutational and topological analysis of the Escherichia coli BamA protein

Browning, Douglas F., Matthews, Sophie A., Rossiter, Amanda E., Sevastsyanovich, Yanina R., Jeeves, Mark, Mason, Jessica L., Wells, Timothy J., Wardius, Catherine A., Knowles, Timothy J., Cunningham, Adam F., Bavro, Vassiliy N., Overduin, Michael and Henderson, Ian R. (2013). Mutational and topological analysis of the Escherichia coli BamA protein. PLoS ONE, 8 (12) e84512, e84512. doi: 10.1371/journal.pone.0084512

Genotypic and phenotypic characterisation of enteroaggregative Escherichia coli from children in Rio de Janeiro, Brazil

Franca, Fernanda L. S., Wells, Timothy J., Browning, Douglas F., Nogueira, Raquel Tayar, Sarges, Felipe Silva, Pereira, Ana Claudia, Cunningham, Adam F., Lucheze, Kely, Paula Rosa, Ana Claudia, Henderson, Ian R. and de Luna, Maria das Gracas (2013). Genotypic and phenotypic characterisation of enteroaggregative Escherichia coli from children in Rio de Janeiro, Brazil. PLoS ONE, 8 (7) e69971, e69971. doi: 10.1371/journal.pone.0069971

Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis

Browning, Douglas F., Wells, Timothy J., Franca, Fernanda L. S., Morris, Faye C., Sevastsyanovich, Yanina R., Bryant, Jack A., Johnson, Matthew D., Lund, Peter A., Cunningham, Adam F., Hobman, Jon L., May, Robin C., Webber, Mark A. and Henderson, Ian R. (2013). Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis. Molecular Microbiology, 87 (5), 939-950. doi: 10.1111/mmi.12144

A generalised module for the selective extracellular accumulation of recombinant proteins

Sevastsyanovich, Yanina R., Leyton, Denisse L., Wells, Timothy J., Wardius, Catherine A., Tveen-Jensen, Karina, Morris, Faye C., Knowles, Timothy J., Cunningham, Adam F., Cole, Jeffrey A. and Henderson, Ian R. (2012). A generalised module for the selective extracellular accumulation of recombinant proteins. Microbial Cell Factories, 11 (69) 69. doi: 10.1186/1475-2859-11-69

Discovery of an archetypal protein transport system in bacterial outer membranes

Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261

Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli

Totsika, Makrina, Wells, Timothy J., Beloin, Christophe, Valle, Jaione, Allsopp, Luke P., King, Nathan P., Ghigo, Jean-Marc and Schembri, Mark A. (2012). Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli. Applied and Environmental Microbiology, 78 (7), 2179-2189. doi: 10.1128/AEM.06680-11

Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins

Leyton, Denisse L., Sevastsyanovich, Yanina R., Browning, Douglas F., Rossiter, Amanda E., Wells, Timothy J., Fitzpatrick, Rebecca E., Overduin, Michael, Cunningham, Adam F. and Henderson, Ian R. (2011). Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins. Journal of Biological Chemistry, 286 (49), 42283-42291. doi: 10.1074/jbc.M111.306118

SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection

Raghunathan, Dhaarini, Wells, Timothy J., Morris, Faye C., Shaw, Robert K., Bobat, Saeeda, Peters, Sarah E., Paterson, Gavin K., Jensen, Karina Tveen, Leyton, Denisse L., Blair, Jessica M. A., Browning, Douglas F., Pravin, John, Flores-Langarica, Adriana, Hitchcock, Jessica R., Moraes, Claudia T. P., Piazza, Roxane M. F., Maskell, Duncan J., Webber, Mark A., May, Robin C., MacLennan, Calman A., Piddock, Laura J., Cunningham, Adam F. and Henderson, Ian R. (2011). SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection. Infection and Immunity, 79 (11), 4342-4352. doi: 10.1128/IAI.05592-11

A commensal gone bad: Complete genome sequence of the prototypical enterotoxigenic escherichia coli strain H10407

Crossman, L. C., Chaudhuri, R. R., Beatson, S. A., Wells, T. J., Desvaux, M., Cunningham, A. F., Petty, N. K., Mahon, V., Brinkley, C., Hobman, J. L., Savarino, S. J., Turner, S. M., Pallen, M. J., Penn, C. W., Parkhill, J., Turner, A. K., Johnson, T. J., Thomson, N. R., Smith, S. G. J. and Henderson, I. R. (2010). A commensal gone bad: Complete genome sequence of the prototypical enterotoxigenic escherichia coli strain H10407. Journal of Bacteriology, 192 (21), 5822-5831. doi: 10.1128/JB.00710-10

Autotransporters of Escherichia coli: A sequence-based characterization

Wells, Timothy J., Totsika, Makrina and Schembri, Mark A. (2010). Autotransporters of Escherichia coli: A sequence-based characterization. Microbiology, 156 (8), 2459-2469. doi: 10.1099/mic.0.039024-0

Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium

Heras, B, Totsika, M, Jarrott, R, Shouldice, SR, Guncar, G, Achard, MES, Wells, TJ, Argente, MP, McEwan, AG and Schembri, MA (2010). Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. Journal of Biological Chemistry, 285 (24), 18423-18432. doi: 10.1074/jbc.M110.101360

UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073

Allsopp, Luke P., Totsika, Makrina, Tree, Jai J., Ulett, Glen C., Mabbett, Amanda N., Wells, Timothy J., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2010). UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073. Infection and Immunity, 78 (4), 1659-1669. doi: 10.1128/IAI.01010-09

The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle

Wells, Timothy J., McNeilly, Tom N., Totsika, Makrina, Mahajan, Arvind, Gally, David L. and Schembri, Mark A. (2009). The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle. Environmental Microbiology, 11 (7), 1803-1814. doi: 10.1111/j.1462-2920.2009.01905.x

EhaA is a novel autotransporter protein of enterohemorrhagic Escherichia coli O157:H7 that contributes to adhesion and biofilm formation

Wells, T.J., Sherlock, O., Rivas, L., Mahajan, A., Beatson, S.A., Torpdahl, M., Webb, R.I., Allsopp, L., Gobius, K., Gally, D.L. and Schembri, M.A. (2008). EhaA is a novel autotransporter protein of enterohemorrhagic Escherichia coli O157:H7 that contributes to adhesion and biofilm formation. Environmental Microbiology, 10 (3), 589-604. doi: 10.1111/j.1462-2920.2007.01479.x

Autotransporter proteins: novel targets at the bacterial cell surface

Wells, T. J., Tree, J. J., Ulett, G. C. and Schembri, M. A. (2007). Autotransporter proteins: novel targets at the bacterial cell surface. Fems Microbiology Letters, 274 (2), 163-172. doi: 10.1111/j.1574-6968.2007.00833.x

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, A., Giri, R., Begun, J., Wells, T., Bergot, A. S. and Thomas, R. (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. EULAR 2023 European Congress of Rheumatology, Milan, Italy, 31 May-3 June 2023. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2023-eular.1346

TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy

Souza-Fonseca-Guimaraes, Fernando, Rossi, Gustavo Rodrigues, Wells, Timothy and McCulloch, Timothy Ryan (2023). TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy. IMMUNOLOGY2023™ Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: The American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.64.14

A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation

Divithotawela, C., Pham, A., Ledger, E. L., Hopkins, P., Tan, M., Yerkovich, S., Wells, T. J. and Chambers, D. C. (2020). A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation. International Society for Heart and Lung Transplantation 40th Annual Meeting and Scientific Sessions, Online, 22 - 25 April 2020. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2020.01.1265

A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation

Divithotawela, C., Pham, A., Ledger, E. L., Hopkins, P., Tan, M., Yerkovich, S., Wells, T. J. and Chambers, D. C. (2020). A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation. 40th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), Montreal, Canada, 22-25 April 2020. New York, NY United States: Elsevier.

Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis

Baillet, Athan, Bhuyan, Zaied Ahmed, Douillard, Claire, Bozon, Aurelie, Armitage, Charles, Romand, Xavier, Minh Vu Chuong Nguyen,, Favier, Bertrand, Wells, Timothy, Beagley, Kenneth and Thomas, Ranjeny (2017). Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Functional genomics of the regulation of nodule number in legumes

Gresshoff, PM, Gualtieri, G, Laniya, T, Indrasumunar, A, Miyahara, A, Nontachaiyapoom, S, Wells, T, Biswas, B, Chan, PK, Scott, P, Kinkema, M, Djordjevic, M, Hoffmann, D, Pregelj, L, Buzas, DM, Li, DX, Men, A, Jiang, Q, Hwang, CH and Carroll, BJ (2005). Functional genomics of the regulation of nodule number in legumes. 14th International Nitrogen Fixation Congress, Beijing, China, 27 October - 1 November 2004. The Netherlands: Springer. doi: 10.1007/1-4020-3570-5

Functional genomic analysis of nodule development in soybean and Lotus Japonicus

Gresshoff, P. M., Carroll, B. J., Gualtieri Gonzalez, G. S., Vickers, C., Kuen, P., Huang, C., Scott, P. T., Kinkema, M. D., Men, A., Stiller, J., Jiang, Q., Laniya, T.S., Buzas, D. M., Miyahara, A., Indrasumunar, A., Nontachaiyapoom, S., Hoffmann, D., Biswas, B., Wells, T. J., So, H., Pregelj, L. and Dong, X. (2004). Functional genomic analysis of nodule development in soybean and Lotus Japonicus. Com Bio 2004, Intercontinental Burswood Resort, Perth, Australia, 26-30 September, 2004.

Identification and characterisation of novel autotransporters of enterohaemorrhagic escherichia coli O157:H7

Wells, Timothy (2008). Identification and characterisation of novel autotransporters of enterohaemorrhagic escherichia coli O157:H7. PhD Thesis, School of Chemistry and Molecular Bioscience, The University of Queensland. doi: 10.14264/178070