Professor Kiarash Khosrotehrani

Professorial Research Fellow

The University of Queensland Diamantina Institute
Faculty of Medicine

Affiliate Associate Professor

Institute for Molecular Bioscience
k.khosrotehrani@uq.edu.au
+61 7 344 37088

Overview

Professor Khosrotehrani is a clinical scientist, dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Diamantina Institute within the Translational Research Institute in Brisbane, Australia. He is also the deputy director of the Australian Skin and Skin Cancer Research Centre in Brisbane. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.

During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). He is currently a fellow of the NHMRC of Australia. The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.

Research Interests

  • Tissue regeneration
    Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
  • Skin cancer
    Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation

Qualifications

  • Doctor's Diploma (Specialist), University of Paris
  • Specialised Study Diploma (Dermatology& Venereolog, University of Paris
  • National Medical Doctor's Diploma

Publications

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Supervision

View all Supervision

Publications

Featured Publications

Book Chapter

  • Patel, Jatin and Khosrotehrani, Kiarash (2018). Fetal endothelial progenitors and mesenchymal stem cells from the human term placenta. Perinatal stem cells. (pp. 131-140) edited by Anthony Atala, Kyle Cetrulo, Rouzbeh Taghizadeh, Curtis Cetrulo and Sean Murphy. Cambridge, MA United States: Academic Press. doi: 10.1016/B978-0-12-812015-6.00009-1

  • Roy, Edwige and Khosrotehrani, Kiarash (2018). Whole-mount immunofluorescent staining coupled to multicolor lineage tracing model for analyzing the spatiotemporal organization of epidermal stem cells. Skin stem cells: methods protocols. (pp. 111-118) edited by Kursad Turksen. New York, NY, United States: Humana Press. doi: 10.1007/7651_2018_165

  • Muerza-Cascante, M.L., Khosrotehrani, K., Haylock, D., Hutmacher, D. W. and Loessner, D. (2017). 5.11 Engineering the haematopoietic stem cell niche in vitro. Comprehensive Biomaterials II. (pp. 187-199) Amsterdam: Elsevier. doi: 10.1016/b978-0-12-803581-8.10129-8

  • Shafiee, Abbas and Khosrotehrani, Kiarash (2016). Perinatal tissue-derived endothelial progenitor cells. Perinatal tissue-derived stem cells: alternative sources of fetal stem cells. (pp. 65-80) edited by Babak Arjmand. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-46410-7_4

  • Seppanen, Elke, Fisk, Nicholas M and Khosrotehrani, Kiarash (2013). Pregnancy-acquired fetal progenitors as natural cell therapy. Perinatal stem cells. (pp. 221-234) edited by Kyle J Cetrulo, Curtis L Cetrulo and Rouzbeh R Taghizadeh. Hoboken, NJ, United States: John Wiley & Sons, Inc.. doi: 10.1002/9781118497883.ch15

  • Leduc, Michele, Aractingi, Selim and Khosrotehrani, Kiarash (2009). Fetal cell microchimerism: a low-grade naturally occurring cell therapy. Perinatal Stem Cells. (pp. 203-208) edited by Curtis L. Cetrulo, Kyle J. Cetrulo and Curtis L. Jr. Cetrulo. Hoboken NJ: John Wiley. doi: 10.1002/9780470480151.ch13

  • Khosrotehrani, Kiarash (2009). Life threatening dermatoses during gestation. Life-threatening dermatoses and emergencies in dermatology. (pp. 175-180) edited by Jean Revuz. Berlin: Springer. doi: 10.1007/978-3-540-79339-7_18

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision