Associate Professor Kristofer Thurecht

NHMRC Career Development Fellow

Centre for Advanced Imaging

Affiliate PRF & Group Leader

Australian Institute for Bioengineering and Nanotechnology
k.thurecht@uq.edu.au
+61 7 334 60344

Overview

Associate Professor Kris Thurecht is a National Health and Medical Research Council (NHMRC) Career Development Fellow (step 2) with appointments at AIBN and UQ’s Centre for Advanced Imaging. Associate Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Associate Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on three patents. He is also CI on two major ARC Centres: The ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader.​ He is co-inventor on three patents.

Research Impacts

Research

Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, A/Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Publications

  • Ratnayake, G., Bain, A. L., Fletcher, N., Howard, C. B., Khanna, K. K. and Thurecht, K. J. (2018) RNA interference to enhance radiation therapy: targeting the DNA damage response. Cancer Letters, 439 14-23. doi:10.1016/j.canlet.2018.09.011

  • Bennett, Thomas M., Chambers, Lewis C., Thurecht, Kristofer J., Jack, Kevin S. and Blakey, Idriss (2018) Dependence of Block Copolymer Domain Spacing and Morphology on the Cation Structure of Ionic Liquid Additives. Macromolecules, . doi:10.1021/acs.macromol.8b01953

  • Faria, Matthew, Björnmalm, Mattias, Thurecht, Kristofer J., Kent, Stephen J., Parton, Robert G., Kavallaris, Maria, Johnston, Angus P. R., Gooding, J. Justin, Corrie, Simon R., Boyd, Ben J., Thordarson, Pall, Whittaker, Andrew K., Stevens, Molly M., Prestidge, Clive A., Porter, Christopher J. H., Parak, Wolfgang J., Davis, Thomas P., Crampin, Edmund J. and Caruso, Frank (2018) Minimum information reporting in bio–nano experimental literature. Nature Nanotechnology, 13 9: 777-785. doi:10.1038/s41565-018-0246-4

View all Publications

Supervision

  • (2018) Doctor Philosophy

  • Master Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2018). Hyperbranched polymers as nanocarriers. In Encyclopedia of polymer science and technology (pp. 1-27) Hoboken, NJ USA: John Wiley & Sons. doi:10.1002/0471440264.pst159.pub2

  • Fletcher, Nicholas and Thurecht, Kristofer (2016). Molecular imaging utilizing Aptamer-targeted probes. In Rakesh N. Veedu (Ed.), Aptamers Tools for Nanotherapy and Molecular Imaging (pp. 287-318) Boca Raton, United States: CRC Press.

  • Barner-Kowollik, Christopher, Blinco, James P., Destarac, Mathias, Thurecht, Kristofer J. and Perrier, Sébastien (2012). Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications. In Chryssostomos Chatgilialoglu and Armido Studer (Ed.), Encyclopedia of radicals in chemistry, biology and materials (pp. 1895-1929) Chichester, West Sussex, U.K.: John Wiley & Sons. doi:10.1002/9781119953678.rad058

  • Peng, Hui, Thurecht, Kristofer, Hsu, Steven, Blakey, Idriss, Squires, Oliver, Kurniawan, Nyoman, Rose, Stephen and Whittaker, Andrew (2011). Effect of molecular architecture on the performance of (19)F NMR imaging agents. In H. N. Cheng, Tetsuo Asakur and Alan D. English (Ed.), NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules (pp. 459-472) Washington, DC, United States: American Chemical Society. doi:10.1021/bk-2011-1077.ch028

  • Thurecht, Kristofer James and Villarroya, Silvia (2010). Biocatalytic Polymerization in Exotic Solvents. In Katja Loos (Ed.), Biocatalysis in Polymer Chemistry (pp. 323-348) Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi:10.1002/9783527632534

Journal Article

Conference Publication

  • Thurecht, Kristofer, Zhou, Yongmei, Fletcher, Nicholas and Houston, Zachary (2018). Development of polymer theranostics to probe the behaviour of nanomaterials in biology. In: 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, (). 18-22 March 2018.

  • Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. In: 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, (). 18-22 March 2018.

  • Carrington, Benjamin, Al-Ejeh, Fares, Lim, Yi Chieh, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Fuchs, Adrian, Thurecht, Kristofer, Stringer, Brett, Boyd, Andrew and Day, Bryan (2016). EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma. In: 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale Az United States, (153-154). Nov 17-20, 2016.

  • Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. In: 10th World Biomaterials Congress, Montréal, Canada, (). 17 May - 22 May 2016. doi:10.3389/conf.FBIOE.2016.01.02237

  • Sabanathan, Dhanusha, Gurney, Howard, Gillatt, David, Trifunovic, Marko, Magnussen, John, Poursoultan, Pirooz, Shon, Kevin H. O., Walsh, Bradley J., Mazure, Hubert, Velonas, Vicki, Thurecht, Kris, Quach Truong, Wissmueller, Sandra and Campbell, Douglas (2016). MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer. In: 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, (14-15). August 31 - September 3 2016.

  • Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. In: 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, (26-26). August 31-September 3 2016.

  • Bennett, Thomas, Blakey, Idriss, Thurecht, Kristofer and Jack, Kevin (2015). Mapping the lyotropic phase behavior of diblock copolymer iongels. In: Abstracts of Papers of the American Chemical Society. American Chemical Society Meeting, , (). .

  • Tse, Brian W-C, Fuchs, Adrian V., Huang, Steve S., Heston, Warren D. W., Yeh, Mei-Chun, Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2015). Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer. In: 2nd Prostate Cancer World Congress (PCWC), Cairns, Australia, (34-34). 17-21 August 2015.

  • Zhang, Cheng , Wang, Kewei , Peng, Hui , Puttick, Simon , Thurecht, Kris and Whittaker, Andrew (2015). Polymeric MRI agents for disease detection: advances and challenges. In: 2015 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, United States, (). 15-20 December 2015.

  • Zhang, Cheng, Wang, Kewei, Thurecht, Kris, Puttick, Simon, Peng, Hui and Whittaker, Andrew (2015). Solution properties of EOGMA-containing macromolecules. In: 4th Federation of Asian Polymer Societies – International Polymer Congress, Kuala Lumpur, Malaysia, (). 5-8 October 2015.

  • Puttick, Simon, Stringer, Brett W., Day, Bryan W., Mardon, Karine, Cowin, Gary J., Fay, Michael, Thurecht, Kristofer J., Whittaker, Andrew K., Boyd, Andrew W. and Rose, Stephen (2014). EphA2 as a diagnostic imaging target in glioblastoma: A PET/MRI study. In: Proceedings: AACR Annual Meeting 2014. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, (). 05-09 April 2014. doi:10.1158/1538-7445.AM2014-LB-12

  • Bennett, Thomas, Pei, Kevin, Cheng, Han-Hao, Thurecht, Kristofe J., Jack, Kevin S. and Blakey, Idriss (2014). Extending the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self assembly. In: Douglas J. Resnick and Christopher Bencher, Proceedings of SPIE: Alternative Lithographic Technologies VI. Alternative Lithographic Technologies VI, San Jose, United States, (). 24-27 February 2014. doi:10.1117/12.2046296

  • Fuchs, Adrian V., Pearce, Amanda K., Tse, Brian W. C., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2014). Multimodal hyperbranched polymers for simultaneous imaging and drug delivery for targeted prostate cancer theranostics. In: ACS 2014: 247th American Chemical Society National Meeting & Exposition, Dallas, TX, USA, (). 16-20 March, 2014.

  • Dey, Priyanka, Olds, William, Blakey, Idriss, Thurecht, Kristofer J., Izake, Emad L. and Fredericks, Peter M. (2014). SERS-barcoded colloidal gold NP assemblies as imaging agents for use in biodiagnostics. In: Anita Mahadevan-Jansen and Wolfgang Petrich, Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry. Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry, San Francisco, CA United States, (). 1-2 February 2014. doi:10.1117/12.2037159

  • Whittaker, Andrew K., Thurecht, Kristofer J., Blakey, Idriss and Peng, Hui (2013). Biologically-responsive polymeric F-19 MRI agents. In: Abstracts of Papers of the American Chemical Society. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, (459-+). 07-11 April 2013.

  • Thurecht, Kristofer J., Whittaker, Andrew K., Russell, Pamela J. and Pearce, Amanda (2013). Hyperbranched polymers in theranostics: Development of advanced delivery probes for cancer therapy. In: Abstracts of Papers of the American Chemical Society. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, (). 07-11 April 2013.

  • Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. In: American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., (). 22 -26 March 2009.

  • Whittaker, AK, Blakey, I, Thurecht, KJ, Squires, O and Varcoe, K (2008). POLY 624-High pressure NMR of polymeric materials. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 235th American-Chemical-Society National Meeting, New Orleans LA, (). APR 06-10, 2008.

  • Rintoul, L., Thurecht, K., Chen, L., Goh, K., Hill, D. J. T. and Whittaker, A. K. (2003). Application of Raman Spectroscopic Mapping for the Characterisation of High Performance Polymers. In: Proceedings of the 5th Australian Conference on Vibrational Spectroscopy (ACOVS). 5th Australian Conference on Vibrational Spectroscopy, Melbourne, (594-595). 29 Sep - 2 Oct 2003.

  • Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Aspects of the radiation chemistry of poly(chlorotrifluoroethylene). In: 25th Australasian Polymer Symposium, Armidale, ((Abstract)). 10-13 February, 2002.

  • Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Radiation chemistry of poly(chlorotrifluoroethylene) for biomedical purposes. In: Qld Polymer Group Satellite Symposium, Brisbane, ((Abstract)). 6-8 February, 2002.

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

Completed Supervision