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Breast cancer is the commonest cancer in women in many countries including Australia, the USA and… CT-X antigen expression in human breast cancer… The role of DEP-1 as a tumour suppressor in breast cancer… , he was Professor of Breast Pathology at The Institute of Cancer Research and The Royal Marsden… Mammographic screening programs were introduced to improve outcomes for women with breast cancer by…
Sunil Lakhani is Executive Director Research and Senior Staff Specialist, Pathology Queensland, and Head of the Molecular Breast Group at the University of Queensland Centre for Clinical Research (UQCCR) at the Royal Brisbane and Women’s Hospital.
Prior to his move to Australia in 2004, he was Prof …
The recognition that ADH is biologically very similar to DCIS has led to a policy of excising all ADH lesions diagnosed on core biopsies at breast screening assessment
The demonstration that LCIS is a clonal neoplastic proliferation with the same molecular phenotype as invasive lobular carcinoma, a …
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skin cancer. Understanding the relationship that genes such as MC1R and the NR4As have to skin… propensity to freckle have been identified as genetic risk factors for skin cancer when combined with… The melanocortin-1 receptor gene polymorphism and association with human skin cancer… Molecular and cellular analysis of MC1R polymorphisms associated with skin cancer risk phenotypes… Skin, hair, eye colour and cancer � MC1R/OCA2, the genetic links… physical trait and the associated genotypic risk for skin cancer. The genes that determine an… respects these cell lines resemble those established from small cell lung cancer (SCLC) and it is…
Our work on human pigmentation genetics has allowed understanding of normal variation in this physical trait and the associated genotypic risk for skin cancer. The genes that determine an individual's skin phototype and the cellular mechanisms that result in the tanning response of melanocytes after …
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. Survivin and XIAP have emerged as attractive targets for cancer therapeutics. This project will… Vincristine pharmacodynamics and pharmacogenetics in children with cancer: A limited-sampling, population modelling approach… Life and health after childhood cancer: a national data linkage cohort study (Cancer Australia grant led by The University of Sydney)… Blood Cancers… local, national and international collaborative research across all childhood cancer types. A/Prof… attractive small molecule targets for cancer therapeutics, with several inhibitors currently in…
Associate Professor Andy Moore is a Paediatric Oncologist and Director of Research at Children's Health Queensland Hospital & Health Service (CHQ). He is also Director of the Queensland Children's Tumour Bank, which is part of UQ's Child Health Research Centre. The Queensland Children's Tumour Bank …
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Breast cancer is the commonest cancer in women in many countries including Australia, the USA and… Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types… The molecular basis of breast cancer in young women… in the UK. His first postdoctoral research position was at the Breakthrough Breast Cancer Research… Our knowledge of the biology underlying the development of brainmetastases (BM) frombreast cancer…
Peter holds a BSc Honours degree and a PhD in Molecular Biology from the University of Liverpool in the UK. His first postdoctoral research position was at the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research, London UK. He moved to Australia in 2005 and helped Professo …
Cancer is a very heterogeneous disease, making morphological classification and management of patients a significant challenge. Despite great advances it remains difficult to predict which patients are at risk of their disease returning (recurrence), spreading (metastasis) or which patients will gai …
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The outcomes and patterns of treatment failure after surgery for locally recurrent rectal cancer… Locally advanced and recurrent rectal cancer… rectal cancer, local recurrence still occurs. For appropriately selected patients, pelvic…
Colorectal Surgeon Brisbane
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development of skin cancers, including melanomas. Over the past 10 years a genetic factors have also been… Histone Deacetylase Inhibition as a Treatment of TRAIL-Resistant Cancers… Preclinical development of combinations with CHK1 inhibitors in melanoma and lung cancer… Targeting defective cell cycle checkpoints in cancers, particularly melanoma… , particularly progression into mitosis. These mechanisms are often mutated in cancers and are likely to… levels of H3K9 modification and HP1 binding in human cancer cells and found only minor effects on H3K9…
Professor Gabrielli completed his undergraduate education at James Cook University in Townsville and PhD at La Trobe University in Melbourne. After two postdoctoral positions in the USA in the emerging field of cell cycle regulation, he was recruited to establish his own independent research at the …
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Can computers conceive the complexity of cancer to cure it? Using artificial intelligence technology in cancer modelling and drug discovery… Advancing Targeted Therapies for Metastatic Breast and Gynaecologic Cancers using RNA-based Therapeutics with Lipid Nanoparticle (LNP) Delivery System… BACKGROUND Cancer ranks as the second leading cause of death globally and Breast cancer (BC… Cancer Biology and Therapeutics… addressing cancer molecular mechanisms with the goal of developing novel cancer therapeutics and… , further complicated in the context of cancer research by the inherent heterogeneity and complexity of…
I am a Principal Investigator (PI) and a senior research officer (SRO) at Mater research – UQ with excellent clinical and research laboratory skills and expertise in conducting and analyzing laboratory assays and resolving complex research and clinical laboratory problems. I can describe myself as …
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The Role of Type XI and Type XVII Collagen in Breast Cancer Progression… Prospective study of breast cancer progression by content analysis of circulating exosomes in serially collected blood samples… Breast Cancer… postdoctoral work focused on understanding the genetic basis of colorectal cancer using… cancer (CRC). In this study, we sought to clarify the expression and role of CD133 in CRC…
Assoc Prof McCart Reed holds an honours degree and a PhD in molecular biology from UQ. Her early postdoctoral work focused on understanding the genetic basis of colorectal cancer using experimental disease models, as part of a Cancer Research UK-funded colorectal cancer program led by Professors Ian …
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The science behind the 7th edition Tumour, Node, Metastasis staging system for lung cancer… Lung cancer screening… ACRF Lung Cancer Screening CENTRE OF EXCELLENCE (LUSCE)… Multiple clinical trials of lung cancer screening… Lung cancer screening… Queensland Thoracic Research Centre. Dr Marshall's research interests are in lung cancer screening/early… Background Lung cancer is the leading cause of cancer-related mortality in Australia. Screening…
Dr Henry Marshall is a Thoracic Physician at The Prince Charles Hospital and University of Queensland Thoracic Research Centre. Dr Marshall's research interests are in lung cancer screening/early detection and smoking cessation. His PhD (UQ 2015) was based on the first trial of lung cancer screening …
Lung cancer is the leading cause of cancer mortality in Australia and the world. Lung cancer screening can reduce mortality by detecting tumours early. Helping people quit smoking reduces future risk of cancer. The team at The Prince Charles Hospital and University of Queensland Thoracic Research Ce …
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Head and neck cancers (HNC) are the 7th most common cancer and account for 2,500 new cases in… Applications in lung, skin, and head and neck cancers.… Transformation or progression from adenocarcinoma to small cell lung cancer detected by serially tracking mutations in the blood… From Pixels to Prognosis: Harnessing single-cell spatial analysis to predict and improve immunotherapy response in lung cancer… approaches in the Asia-Pacific region, contributing to world-first studies for lung cancer, head… cancers (HNCs). Whilst the prognostic and predictive value of single CTCs have been well documented…
Dr Arutha Kulasinghe is a Senior Research Fellow and leads the Clinical-oMx Lab at the University of Queensland. Dr Kulasinghe has pioneered spatial transcriptomics using digital spatial profiling approaches in the Asia-Pacific region, contributing to world-first studies for lung cancer, head and ne …