Drug development and delivery
Our group’s work concerns the development of novel drug candidates, especially neuroactive drugs. We study chemical techniques to improve the delivery of drugs across the GI tract and the Blood Brain Barrier.
Journal Article: Special Issue in Honor of Professor Mary Garson AM
Blanchfield, Joanne T., Nonato, Maribel G. and Clark, Richard J. (2023). Special Issue in Honor of Professor Mary Garson AM. Journal of Natural Products, 86 (3), 473-474. doi: 10.1021/acs.jnatprod.3c00088
Journal Article: Phytochemical composition of Denhamia obscura (A. Rich.) Meisn. Ex Walp. root bark, seeds and leaves
Jesus, Matheus Carpinelli De, Wapling, Johanna, Kiem, Eunice, Stockdale, Tegan, Whittaker, Jacob J., Clegg, Jack K., Leach, David, Church, Taylah, Collins, Raelene, Leach, Greg, Hewitt, David, De Voss, James J. and Blanchfield, Joanne T. (2022). Phytochemical composition of Denhamia obscura (A. Rich.) Meisn. Ex Walp. root bark, seeds and leaves. Arkivoc, 2022 (4), 123-142. doi: 10.24820/ark.5550190.p011.828
Journal Article: Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain
Kong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889
(2020–2022) Commonwealth Defence Science and Technology Group
(2015–2016) Technology-Enhanced Learning Grants
Bioproduction and bioavailability of steroidal saponins, bioactives in herbal medicines
(2014–2017) ARC Linkage Projects
Decontamination of fentanyl and fentanyl analogues
(2023) Doctor Philosophy
The construction of synthetic mimics of complex conformational epitopes of HIV
Doctor Philosophy
Phytochemical characterisation of Australian medicinal plants: Doctrina veteris et novi
(2021) Doctor Philosophy
Modification of peptides and other drugs using lipoamino acids and sugars
Blanchfield, J. T. and Toth, I. (2005). Modification of peptides and other drugs using lipoamino acids and sugars. Methods in Molecular Biology: Peptide Synthesis and Applications. (pp. 45-61) edited by John Howl. New Jersey: Humana Press. doi: 10.1385/1-59259-877-3:045
Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity
Toth, Istvan, McGeary, Ross, Blanchfield, Joanne, Rhee, Handoo, Alewood, Paul, Adams, David and Good, Michael (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity. Peptides: The Wave of the Future. (pp. 937-939) edited by Michal Lebl and Richard A. Houghten. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/978-94-010-0464-0_437
Special Issue in Honor of Professor Mary Garson AM
Blanchfield, Joanne T., Nonato, Maribel G. and Clark, Richard J. (2023). Special Issue in Honor of Professor Mary Garson AM. Journal of Natural Products, 86 (3), 473-474. doi: 10.1021/acs.jnatprod.3c00088
Phytochemical composition of Denhamia obscura (A. Rich.) Meisn. Ex Walp. root bark, seeds and leaves
Jesus, Matheus Carpinelli De, Wapling, Johanna, Kiem, Eunice, Stockdale, Tegan, Whittaker, Jacob J., Clegg, Jack K., Leach, David, Church, Taylah, Collins, Raelene, Leach, Greg, Hewitt, David, De Voss, James J. and Blanchfield, Joanne T. (2022). Phytochemical composition of Denhamia obscura (A. Rich.) Meisn. Ex Walp. root bark, seeds and leaves. Arkivoc, 2022 (4), 123-142. doi: 10.24820/ark.5550190.p011.828
Kong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889
Ayub, Muhammad Adnan, Hanif, Muhammad Asif, Blanchfield, Joanne, Zubair, Muhammad, Abid, Muhammad Amin and Saleh, Muhammad Tahir (2022). Chemical composition and antimicrobial activity of Boswellia serrata oleo-gum-resin essential oil extracted by superheated steam. Natural Product Research, 1-6. doi: 10.1080/14786419.2022.2044327
Smith, Matthew, Logan, Mike, Bazley, Mikaela, Blanchfield, Joanne, Stokes, Robert, Blanco, Ana and McGee, Rachel (2021). A Semi-quantitative method for the detection of fentanyl using surface-enhanced Raman scattering (SERS) with a handheld Raman instrument. Journal of Forensic Sciences, 66 (2), 505-519. doi: 10.1111/1556-4029.14610
Caco-2 cell permeability of flavonoids and saponins from Gynostemma pentaphyllum: the immortal herb
Ahmed, Iftekhar, Leach, David N., Wohlmuth, Hans, De Voss, James J. and Blanchfield, Joanne T. (2020). Caco-2 cell permeability of flavonoids and saponins from Gynostemma pentaphyllum: the immortal herb. ACS Omega, 5 (34) acsomega.0c02180, 21561-21569. doi: 10.1021/acsomega.0c02180
Fletcher, Mary T., Hungerford, Natasha L., Webber, Dennis, Carpinelli de Jesus, Matheus, Zhang, Jiali, Stone, Isobella S. J., Blanchfield, Joanne T. and Zawawi, Norhasnida (2020). Stingless bee honey, a novel source of trehalulose: a biologically active disaccharide with health benefits. Scientific Reports, 10 (1) 12128, 1-8. doi: 10.1038/s41598-020-68940-0
Bazley, Mikaela M., Logan, Michael, Baxter, Christina, Robertson, Avril A. B. and Blanchfield, Joanne T. (2020). Decontamination of fentanyl and fentanyl analogues in field and laboratory settings: a review of fentanyl degradation. Australian Journal of Chemistry, 73 (10), 868-879. doi: 10.1071/CH19669
Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance
Stone, M. Rhia L., Łapińska, Urszula, Pagliara, Stefano, Masi, Muriel, Blanchfield, Joanne T., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance. RSC Chemical Biology, 1 (5), 395-404. doi: 10.1039/d0cb00118j
Carpinelli de Jesus, Matheus, Hungerford, Natasha L., Carter, Steve J., Anuj, Shalona R., Blanchfield, Joanne T., De Voss, James Joseph and Fletcher, Mary T. (2019). Pyrrolizidine alkaloids of Blue Heliotrope (Heliotropium amplexicaule) and their presence in Australian honey. Journal of Agricultural and Food Chemistry, 67 (28) acs.jafc.9b02136, 7995-8006. doi: 10.1021/acs.jafc.9b02136
Stockdale, Tegan P., Challinor, Victoria L., Lehmann, Reginald P., De Voss, James J. and Blanchfield, Joanne T. (2019). Caco-2 monolayer permeability and stability of Chamaelirium luteum (false unicorn) open-chain steroidal saponins. ACS Omega, 4 (4), 7658-7666. doi: 10.1021/acsomega.9b00496
Dewi, Ariyanti S., Pierens, Gregory K., Cheney, Karen L., Blanchfield, Joanne T. and Garson, Mary J. (2018). Chromolactol, an Oxygenated Diterpene from the Indo-Pacific Nudibranch Goniobranchus coi: Spectroscopic and Computational Studies. Australian Journal of Chemistry, 71 (10), 798-803. doi: 10.1071/CH18243
Dewi, Ariyanti S., Cheney, Karen L., Urquhart, Holly H., Blanchfield, Joanne T. and Garson, Mary J. (2016). The sequestration of oxy-polybrominated diphenyl ethers in the nudibranchs Miamira magnifica and Miamira miamirana. Marine Drugs, 14 (11) 198, 198. doi: 10.3390/md14110198
White, Andrew M., Dewi, Ariyanti S., Cheney, Karen L., Winters, Anne E., Blanchfield, Joanne T. and Garson, Mary J. (2016). Oxygenated diterpenes from the Indo-Pacific nudibranchs Goniobranchus splendidus and Ardeadoris egretta. Natural Product Communications, 11 (7), 921-924. doi: 10.1177/1934578X1601100714
The synthesis and ring-opening metathesis polymerization of glycomonomers
Weaver, Lucy G., Singh, Yogendra, Burn, Paul L. and Blanchfield, Joanne T. (2016). The synthesis and ring-opening metathesis polymerization of glycomonomers. RSC Advances, 6 (37), 31256-31264. doi: 10.1039/c5ra25732h
Yong, Ken W. L., Mudianta, I. Wayan, Cheney, Karen L., Mollo, Ernesto, Blanchfield, Joanne T. and Garson, Mary J. (2015). Isolation of norsesterterpenes and spongian diterpenes from Dorisprismatica (= Glossodoris) atromarginata. Journal of Natural Products, 78 (3), 421-430. doi: 10.1021/np500797b
Namjoshi, Sarika, Toth, Istvan, Blanchfield, Joanne T., Trotter, Nicholas, Mancera, Ricardo L. and Benson, Heather A. E. (2014). Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights. Pharmaceutical Research, 31 (12), 3304-3312. doi: 10.1007/s11095-014-1420-5
Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway
Cros, Cécile D., Toth, Istvan and Blanchfield, Joanne T. (2014). Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway. Bioorganic and Medicinal Chemistry Letters, 24 (5), 1373-1375. doi: 10.1016/j.bmcl.2014.01.041
Mölzer, Christine, Huber, Hedwig, Steyrer, Andrea, Ziesel, Gesa V., Wallner, Marlies, Hong, Hung T., Blanchfield, Joanne T., Bulmer, Andrew C. and Wagner, Karl-Heinz (2014). Erratum: Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: A mechanism for antigenotoxic action against a model epoxide (J. Nat. Prod. (2013) 76 (1958-1965) DOI: 10.1021/np4005807). Journal of Natural Products, 77 (2), 436-436. doi: 10.1021/np500101y
Carbohydrate globules: molecular asterisk-cored dendrimers for carbohydrate presentation
Weaver, Lucy G., Singh, Yogendra, Vamvounis, George, Wyatt, Mark F., Burn, Paul L. and Blanchfield, Joanne T. (2014). Carbohydrate globules: molecular asterisk-cored dendrimers for carbohydrate presentation. Polymer Chemistry, 5 (4), 1173-1179. doi: 10.1039/c3py01123b
Acanthocyclamine A from the Indonesian marine sponge Acanthostrongylophora ingens
Dewi, Ariyanti S., Hadi, Tri A., Fajarningsih, Nurrahmi D., Blanchfield, Joanne T., Bernhardt, Paul V. and Garson, Mary J. (2014). Acanthocyclamine A from the Indonesian marine sponge Acanthostrongylophora ingens. Australian Journal of Chemistry, 67 (8-9), 1205-1210. doi: 10.1071/CH14107
Sharpe, Philip C. and Blanchfield, Joanne T. (2014). Chemistry for the masses. International Journal of Innovation in Science and Mathematics Education, 22 (4), 33-47.
Katavic, Peter L., Jumaryatno, Pinus, Hooper, John N. A., Blanchfield, Joanne T. and Garson, Mary J. (2013). Erratum: Oxygenated terpenoids from the Australian sponges Coscinoderma matthewsi and Dysidea sp., and the nudibranch Chromodoris albopunctata (Australian Journal of Chemistry (2012) 65:5 (531-538)). Australian Journal of Chemistry, 66 (11). doi: 10.1071/CH12010-CO
Mölzer, Christine, Huber, Hedwig, Steyrer, Andrea, Ziesel, Gesa V., Wallner, Marlies, Hong, Hung T., Blanchfield, Joanne T., Bulmer, Andrew C. and Wagner, Karl-Heinz (2013). Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide. Journal of Natural Products, 76 (10), 1958-1965. doi: 10.1021/np4005807
Katavic, Peter L., Yong, Ken W. L., Herring, Joel N., Deseo, Myrna A., Blanchfield, Joanne T., Ferro, Vito and Garson, Mary J. (2013). Structure and stereochemistry of an anti-inflammatory anhydrosugar from the Australian marine sponge Plakinastrella clathrata and the synthesis of two analogues. Tetrahedron, 69 (37), 8074-8079. doi: 10.1016/j.tet.2013.06.079
Endomorphin derivatives with improved pharmacological properties
Varamini, Pegah, Blanchfield, Joanne T. and Toth, Istvan (2013). Endomorphin derivatives with improved pharmacological properties. Current Medicinal Chemistry, 20 (22), 2741-2758. doi: 10.2174/0929867311320220002
Cyclic peroxides from a two-sponge association of Plakortis communis-Agelas mauritiana
Jumaryatn, Pinus, Lambert, Lynette K., Hooper, John N. A., Blanchfield, Joanne T. and Garson, Mary J. (2013). Cyclic peroxides from a two-sponge association of Plakortis communis-Agelas mauritiana. Natural Product Communications, 8 (6), 725-728. doi: 10.1177/1934578x1300800611
Identification of bacterial protein O-Oligosaccharyltransferases and their glycoprotein substrates
Schulz, Benjamin L., Jen, Freda E. C., Power, Peter M., Jones, Christopher E., Fox, Kate L., Ku, Shan C., Blanchfield, Joanne T. and Jennings, Michael P. (2013). Identification of bacterial protein O-Oligosaccharyltransferases and their glycoprotein substrates. PLoS One, 8 (5) e62768, e62768.1-e62768.11. doi: 10.1371/journal.pone.0062768
A simple iterative method for the synthesis of beta-(1 -> 6)-glucosamine oligosaccharides
Weaver, Lucy G., Singh, Yogendra, Blanchfield, Joanne T. and Burn, Paul L. (2013). A simple iterative method for the synthesis of beta-(1 -> 6)-glucosamine oligosaccharides. Carbohydrate Research, 371, 68-76. doi: 10.1016/j.carres.2013.01.008
Varamini, Pegah, Goh, Wei Huang, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2013). Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation. Bioorganic & Medicinal Chemistry, 21 (7), 1898-1904. doi: 10.1016/j.bmc.2013.01.044
Somerville, Michael J., Katavic, Peter L., Lambert, Lynette K., Pierens, Gregory K., Blanchfield, Joanne T., Cimino, Guido, Mollo, Ernesto, Gavagnin, Margherita, Banwell, Martin G. and Garson, Mary J. (2012). Isolation of thuridillins D−F, diterpene metabolites from the Australian sacoglossan mollusk Thuridilla splendens; relative configuration of the epoxylactone ring. Journal of Natural Products, 75 (9), 1618-1624. doi: 10.1021/np300442s
Varamini, Pegah, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2012). Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation. PLoS One, 7 (8 Article. No.e41909) e41909, e41909. doi: 10.1371/journal.pone.0041909
Synthesis and biological evaluation of an orally active glycosylated endomorphin-1
Varamini, Pegah, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2012). Synthesis and biological evaluation of an orally active glycosylated endomorphin-1. Journal of Medicinal Chemistry, 55 (12), 5859-5867. doi: 10.1021/jm300418d
Katavic, Peter L., Jumaryatno, Pinus, Hooper, John N. A., Blanchfield, Joanne T. and Garson, Mary J. (2012). Oxygenated terpenoids from the australian sponges Coscinoderma matthewsi and dysidea sp., and the nudibranch Chromodoris albopunctata. Australian Journal of Chemistry, 65 (5), 531-538. doi: 10.1071/CH12010
Steroidal saponins from the roots of Smilax sp.: Structure and bioactivity
Challinor, Victoria L., Parsons, Peter G., Chap, Sonet, White, Eve F., Blanchfield, Joanne T., Lehmann, Reginald P. and De Voss, James J. (2012). Steroidal saponins from the roots of Smilax sp.: Structure and bioactivity. Steroids, 77 (5), 504-511. doi: 10.1016/j.steroids.2012.01.009
Bulmer, A. C., Coombes, J. S., Blanchfield, J. T., Toth, I., Fassett, R. G. and Taylor, S. M. (2011). Bile pigment phamacokinetics and absorption in the rat: Therapeutic potential for enteral administration. British Journal of Pharmacology, 164 (7), 1857-1870. doi: 10.1111/j.1476-5381.2011.01413.x
A direct, heavy metal free synthesis of the β-1,6-linked GlcNAc disaccharide
Weaver, Lucy G., Foster, Melissa, Singh, Yogendra, Burn, Paul L. and Blanchfield, Joanne T. (2011). A direct, heavy metal free synthesis of the β-1,6-linked GlcNAc disaccharide. Australian Journal of Chemistry, 64 (5), 536-539. doi: 10.1071/CH11055
Cros, Cecile D., Toth, Istvan and Blanchfield, Joanne T. (2011). Lipophilic derivatives of leu-enkephalinamide: In vitro permeability, stability and in vivo nasal delivery. Bioorganic and Medicinal Chemistry, 19 (4), 1528-1534. doi: 10.1016/j.bmc.2010.12.042
A novel synthetic adjuvant enhances dendritic cell function
Phillipps, Karen S. M., Wykes, Michelle N., Liu, Xue Q., Brown, Melissa, Blanchfield, Joanne T. and Toth, Istvan (2009). A novel synthetic adjuvant enhances dendritic cell function. Immunology, 128 (1), e582-e588. doi: 10.1111/j.1365-2567.2008.03038.x
Phonchaiya, S., Panijpan, B., Rajviroongit, S., Wright, T. and Blanchfield, J. T. (2009). A facile solvent-free Cannizzaro reaction: An instructional model for introductory organic chemistry laboratory. Journal of Chemical Education, 86 (1), 85-86. doi: 10.1021/ed086p85
Bulmer, Andrew C., Blanchfield, Joanne T., Toth, Istvan, Fassett, Robert G. and Coombes, Jeff S. (2008). Improved resistance to serum oxidation in Gilbert's syndrome: A mechanism for cardiovascular protection. Atherosclerosis, 199 (2), 390-396. doi: 10.1016/j.atherosclerosis.2007.11.022
Del Borgo, Mark P., Blanchfield, Joanne T. and Toth, Istvan (2008). Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorganic & Medicinal Chemistry, 16 (8), 4341-4346. doi: 10.1016/j.bmc.2008.02.074
Rungprom, W., Siwu, E.R.O., Lambert, L.K., Dechsakulwatana, C., Barden, M.C., Kokpol, U., Blanchfield, J. T., Kita, M. and Garson, M. J. (2008). Cyclic tetrapeptides from marine bacteria associated with the seaweed Diginea sp.and the sponge Halisarca ectofibrosa. Tetrahedron, 64 (14), 3147-3152. doi: 10.1016/j.tet.2008.01.089
Bulmer, A.C., Blanchfield, J.T., Coombes, J.S. and Toth, I. (2008). In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdin. Bioorganic & Medicinal Chemistry, 16 (7), 3616-3625. doi: 10.1016/j.bmc.2008.02.008
Koda, Y., Liang, M., Blanchfield, J. T. and Toth, I. (2008). In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogue. International Journal of Pharmaceutics, 356 (1-2), 37-43. doi: 10.1016/j.ijpharm.2007.12.036
Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides
Koda, Y., Del Borgo, M., Wessling, S., Lazarus, L. H., Okada, Y., Toth, I. and Blanchfield, J. T. (2008). Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. Bioorganic & Medicinal Chemistry, 16 (11), 6286-6296. doi: 10.1016/j.bmc.2008.04.020
The anti-mutagenic properties of bile pigments
Bulmer, A., Ried, K., Blanchfield, J. and Wagner, K. (2008). The anti-mutagenic properties of bile pigments. Mutation Research, 658 (1-2), 28-41. doi: 10.1016/j.mrrev.2007.05.001
Jumaryatno, Pinus, Stapleton, Bronwin L., Hooper, John N. A., Brecknell, Douglas J., Blanchfield, Joanne T. and Garson, Mary J. (2007). A comparison of sesquiterpene scaffolds across different populations of the tropical marine sponge Acanthella cavernosa. Journal of Natural Products, 70 (11), 1725-1730. doi: 10.1021/np070156d
Isocyanates in marine sponges: Axisocyanate-3, a new sesquiterpene from Acanthella cavernosa
Jumaryatno, Pinus, Rands-Trevor, Karen, Blanchfield, Joanne T. and Garson, Mary J. (2007). Isocyanates in marine sponges: Axisocyanate-3, a new sesquiterpene from Acanthella cavernosa. ARKIVOC, 2007 (vii), 157-166. doi: 10.3998/ark.5550190.0008.713
Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue
Blanchfield, J., Gallagher, O., Cros, C., Lewis, R., Alewood, P. and Toth, I. (2007). Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochemical and Biophysical Research Communication, 361 (1), 97-102. doi: 10.1016/j.bbrc.2007.06.138
Wessling, Susanne T., Ross, Benjamin P., Koda, Yasuko, Blanchfield, Joanne T. and Toth, Istvan (2007). Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Bioorganic & Medicinal Chemistry, 15 (14), 4946-4950. doi: 10.1016/j.bmc.2007.04.042
The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test
Bulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008
Koda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051
Permeability studies of Kavalactones using a Caco-2 cell monolayer model
Matthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x
Kim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057
Caccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5
Wu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205
Particulate systems as adjuvants and carriers for peptide and protein antigens
Liang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029
Parekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029
Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery
Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977
Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069
Ross, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d
Boric acid catalyzed chemoselective esterification of alpha-hydroxycarboxylic acids
Houston, T. A., Wilkinson, B. L. and Blanchfield, J. T. (2004). Boric acid catalyzed chemoselective esterification of alpha-hydroxycarboxylic acids. Organic Letters, 6 (5), 679-681. doi: 10.1021/ol036123g
Blanchfield, Joanne T., Chow, Sharon, Bernhardt, Paul V., Kennard, Colin H. L. and Kitching, William (2004). Concerning the proposed structure of (+)-laurobtusol: Spectral discrepancies with synthetic, racemic Stereoisomers. Australian Journal of Chemistry, 57 (7), 673-676. doi: 10.1071/CH04047
Lipid, sugar and liposaccharide based delivery systems 2
Blanchfield, J. and Toth, I. (2004). Lipid, sugar and liposaccharide based delivery systems 2. Current Medicinal Chemistry, 11 (17), 2375-2382. doi: 10.2174/0929867043364621
Mucosal immunization: Adjuvants and delivery systems
Moyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588
Matthias, A., Blanchfield, J. T., Penman, K. G., Toth, I., Lang, C. S., De Voss, J. J. and Lehmann, R. P. (2004). Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy And Therapeutics, 29 (1), 7-13. doi: 10.1046/j.1365-2710.2003.00530.x
Back to (non)-Basics: Recent developments in neutral and charge-balanced glycosidase inhibitors
Houston, T. A. and Blanchfield, J. T. (2003). Back to (non)-Basics: Recent developments in neutral and charge-balanced glycosidase inhibitors. Mini Reviews in Medicinal Chemistry, 3 (7), 669-678. doi: 10.2174/1389557033487827
Stability of multielectron bubbles against single-electron split-off
Silvera, I. F., Blanchfield, J. and Tempere, J. (2003). Stability of multielectron bubbles against single-electron split-off. Physica Status Solidi (B) Basic Research, 237 (1), 274-279. doi: 10.1002/pssb.200301792
Blanchfield, J. T., Dutton, J. T., Hogg, R. C., Gallagher, O. P., Craik, D. J., Jones, A., Adams, D. J., Lewis, R. J., Alewood, P. F. and Toth, I. (2003). Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. Journal of Medicinal Chemistry, 46 (7), 1266-1272. doi: 10.1021/jm020426j
Characterisation of alkaloids from some Australian Stephania (Menispermaceae) species
Blanchfield, J. T., Sands, D. P. A., Kennard, C. H. L., Byriel, K. A. and Kitching, W. (2003). Characterisation of alkaloids from some Australian Stephania (Menispermaceae) species. Phytochemistry, 63 (6), 711-720. doi: 10.1016/S0031-9422(03)00240-1
The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII
Blanchfield, Joanne T., Dutton, Julie T., Hogg, R. C., Craik, D. J., Adams, D. J., Lewis, R. J., Alewood, P. and Toth, I. (2001). The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII. Letters in Peptide Science, 8 (3-5), 235-239. doi: 10.1023/A:1016577832311
Three unusal reactions mediate carbapenem and carbapenam biosynthesis
Rongfeng, L., Stapon, A., Blanchfield, J. T. and Townsend, C. A. (2000). Three unusal reactions mediate carbapenem and carbapenam biosynthesis. Journal of the American Chemical Society, 122 (38), 9296-9297. doi: 10.1021/ja0017231
Caloundrin-B and Funiculatin-A - New Polypropionates From Siphonariid Limpets
Blanchfield, JT, Brecknell, DJ, Brereton, IM, Garson, MJ and Jones, DD (1994). Caloundrin-B and Funiculatin-A - New Polypropionates From Siphonariid Limpets. Australian Journal of Chemistry, 47 (12), 2255-2269. doi: 10.1071/CH9942255
Alkaloids from some Australian Stephania (Menispermaceae) species
Blanchfield, Joanne T., Kitching, William, Sands, Donald P.A., Thong, Y. H., Kennard, Colin H.L. and Byriel, Karl A. (1993). Alkaloids from some Australian Stephania (Menispermaceae) species. Natural Product Letters, 3 (4), 305-312. doi: 10.1080/10575639308043881
Devoss, JJ, Jamie, JF, Blanchfield, JT, Fletcher, MT, Oshea, MG and Kitching, W (1991). Mercury(II)-mediated routes to some side-chain functionalised 1,7-dioxaspiro[5.5]undecanes. Applications of Luche-Barbier chemoselective addition to ketoaldehydes. Tetrahedron, 47 (10-11), 1985-1996. doi: 10.1016/S0040-4020(01)96110-1
Stingless bee honeys feature an unusual bioactive sugar, trehalulose
Hungerford, N. L., Zhang, J., Smith, T. J., Yates, H. S. A., Carpinelli de Jesus, M., Webber, D., Stone, I. S. J. , Blanchfield, J. T., Zawawi, N. and Fletcher, M. T. (2022). Stingless bee honeys feature an unusual bioactive sugar, trehalulose. 3rd Australian Native Bee Conference, Rosehill, NSW Australia, 11-12 June 2022.
Stingless bees produce honey rich in the beneficial disaccharide, trehalulose
Hungerford, Natasha L., Zhang, Jiali, Smith, Tobias J., Carpinelli de Jesus, Matheus, Yates, Hans S. A., Chowdhury, Sadia A., Carter, James F., Webber, Dennis, Stone, Isobella S. J., Blanchfield, Joanne T., Zawawi, Norhasnida, Schirra, Horst J., Tran, Trong D. and Fletcher, Mary T. (2021). Stingless bees produce honey rich in the beneficial disaccharide, trehalulose. Symposium of Research & Innovation for Food (SoRIF), Universiti Teknologi MARA, Malaysia via WebEX, 23-24 June 2021.
Stingless Bee Honey’s unique properties
Hungerford, Natasha L., Zhang, Jiali, Smith, Tobias J., Carpinelli de Jesus, Matheus, Yates, Hans S. A., Chowdhury, Sadia A., Carter, James F., Webber, Dennis, Stone, Isobella S. J., Blanchfield, Joanne T., Zawawi, Norhasnida and Fletcher, Mary T. (2021). Stingless Bee Honey’s unique properties. Australian Apitherapy Association Global Conference 2021, Online, 26-27 November 2021.
Stingless bee honey as a unique source of trehalulose
Hungerford, Natasha L., Zhang, Jiali, Carpinelli de Jesus, Matheus, Yates, Hans, Webber, Dennis, Stone Isolbella S. J., Blanchfield, Joanne T., Zawawi, Norhasnida and Fletcher, Mary T. (2020). Stingless bee honey as a unique source of trehalulose. 5th Queensland Annual Chemistry Symposium, QACS 2020, Brisbane, QLD Australia, 27 November 2020.
Matheus Carpinelli de Jesus, Natasha Hungerford, Steve Carter, Shalona Anuj, Joanne Blanchfield, James De Voss and Mary Fletcher (2018). Identifying the pyrrolizidine alkaloid LC-MS/MS profile of Blue heliotrope (Heliotropium amplexicaule). QMSS 2018 – 3rd Queensland Mass Spectrometry Symposium, QUT, Brisbane, 6-7 December 2018.
Pyrrolizidine alkaloids in Blue Heliotrope (Heliotropium amplexicaule) in Australia
Carpinelli de Jesus, M., Hungerford, N. L., Carter, S. J., Anuj, S. R., De Voss, J. J., Blanchfield, J. T. and Fletcher, M. T. (2018). Pyrrolizidine alkaloids in Blue Heliotrope (Heliotropium amplexicaule) in Australia. 10th International Symposium of Poisonous Plants (ISOPP10), St George, Utah, United States, 16-20 September 2018.
New bromotyrosine derivative from an Australian sponge
Jumaryatno, Pinus, Blanchfield, Joanne and Garson, Mary (2011). New bromotyrosine derivative from an Australian sponge. 27th International Symposium on the Chemistry of Natural Products and the 7th International Conference on Biodiversity, Brisbane, Australia, 10-15 July 2011. International Union of Pure and Applied Chemistry.
Development of a carbohydrate based synthetic vaccine to Staphylococcus aureus
Blanchfield, J. T., Burn, P., Colditz, I., Foster, M., Singh, Y., Weaver, L. and Vamvounis, G. (2010). Development of a carbohydrate based synthetic vaccine to Staphylococcus aureus. Pacifichem 2010, International Chemical Congress of Pacific Basin Societies, Honolulu, Hawai'i, 15-20 December 2010.
New chromodorolide metabolites from an Australian marine sponge
Jumaryatno, P., Blanchfield, J. T. and Garson, M. J. (2010). New chromodorolide metabolites from an Australian marine sponge. 6th Annual RHD Symposium of the School of Chemistry & Molecular Biosciences, Brisbane, Australia, 25 Nov 2010.
The CASPiE experience: Undergraduate research in the 1st year chemistry laboratory
Lawrie, Gwen, Adams, Denise, Blanchfield, Joanne and Gahan, Lawrence (2009). The CASPiE experience: Undergraduate research in the 1st year chemistry laboratory. UniServe Science Conference, Sydney, 2009. Sydney, Australia: University of Technology, Sydney.
The CASPiE experience: undergraduate research in the 1st year chemistry laboratory
Lawrie, Gwen, Adams, Denise, Blanchfield, Joanne and Gahan, Lawrence R. (2009). The CASPiE experience: undergraduate research in the 1st year chemistry laboratory. 2009 National UniServe Science Conference, Sydney, NSW, Australia, 30 September-2 October, 2009. Sydney, NSW, Australia: UniServe Science.
Absorption and pharmacokinetics of bilirubin and biliverdin administration in the rat
Bulmer, A.C., Coombes, J.S., Blanchfield, J.T., Toth, I. and Taylor, S.M. (2008). Absorption and pharmacokinetics of bilirubin and biliverdin administration in the rat. Australian Health and Medical Research Congress, Brisbane, 16 - 21 November, 2008.
Bulmer, A. C., Blanchfield, J. T., Toth, I., Fassett, R. G. and Coombes, J. S. (2008). Improved resistance to serum oxidation in Gilberts syndrome: a mechanism for cardiovascular protection. The 2008 meeting of the Society for Free Radical Research - Europe (SFRR-E, Berlin, Germany, 5th-9th July 2008. London: Gordon and Breach. doi: 10.1080/10715760802207914
Bulmer, A. C., Coombes, J. S., Blanchfield, J. T., Toth, I., Fassett, R. G. and Taylor, S. M. (2008). Intestinal and intraperitoneal absorption and bioavailability of the antioxidants unconjugated bilirubin, biliverdin and bilirubin ditaurate in the rat. SFRR-E Berlin, Berlin, Germany, 5-9 July, 2008. London: Gordon and Breach. doi: 10.1080/10715760802207914
Stereochemistry and medicinal natural products: Pitfalls and progress
Garson, M.J., Rudiyansyah, Rands-Trevor, K., Suciati, Suciati, Yong, K.W.L., Lambert, L.K., Ross, B.P. and Blanchfield, J.T. (2008). Stereochemistry and medicinal natural products: Pitfalls and progress. The Halpern Symposium, Wollongong, Australia, July, 2008.
Structural and biosynthetic studies on marine terpene metabolites
Garson, M.J., Rands-Trevor, K., Yong, K.W.L. and Blanchfield, J.T. (2008). Structural and biosynthetic studies on marine terpene metabolites. 26th International Symposium on the Chemistry of Natural Products & 6th International Conference on Biodiversity, Charlottetown, Canada, July, 2008.
Rands-Trevor, K., Blanchfield, J.T. and Garson, M.J. (2008). The synthesis of [14C]-labelled axisonitrile-3 and its biotransformation in the marine sponge Acantheall cavernosa. Natural Product Group NSW Branch RACI Annual One-Day Meeting, Lismore, Australia, October 2008.
Rands-Trevor, K.L., Blanchfield, J.T. and Garson, M.J. (2008). The synthesis of [14C]-labelled axisonitrile-3 and its biotransformation in the marine sponge Acantheall cavernosa. SMMS Research Higher Degree Symposium, Brisbane, Australia, 25 Nov, 2008. Brisbane:
Myatt, Paula, Farrand, Kirsten, Wegener, Margaret and Blanchfield, Joanne (2008). Undergraduate research experiences: Bridging the gap between teaching and research in a research intensive university. 31st Annual HERDSA Conference 2008, Rotorua, New Zealand, 1-4 July, 2008. Higher Education Research and Development Society of Australasia.
Chemical variation in the sponge Acanthella cavernosa from South East Queensland
Jumaryatno, P., Blanchfield, J. T. and Garson, M. J. (2007). Chemical variation in the sponge Acanthella cavernosa from South East Queensland. 12th Asian Chemical Congress (12ACC) 2007, Kuala Lumpur, 23 - 25 August, 2007.
Rungprom, W., Lambert, L.K., Dechsakulwatana, C., Barden, M.C., Blanchfield, J.T. and Garson, M.J. (2007). Cyclic tetrapeptides from a marine bacterium Pseudoalteromonas sp. associated with the Thai sponge Halisarca ectofibrosa. Workshop and seminar on Chemistry, biological activities and biodiversity of marine organisms, Chonburi, Thailand, 6-8 November, 2007.
Blanchfield, J., McGraw, E., Bulmer, M., Thier, R., Byers, H., Myatt, P., Hamilton, S. and Evans, R. (2007). The Advanced Study Program in Science: challenging, motivating and inspiring our best science students. Assessment in Science Teaching and Learning Symposium, The University of Sydney, September 28 & 29, 2007. University of Sydney: UniServe Science.
Rands-Trevor, K., Blanchfield, J.T. and Garson, M.J. (2007). The synthesis of [14C]-labelled axisonitrile-3 and its biotransformation in the marine sponge Acanthella cavernoa: Axisocyanate-3 and the formation of dimeric ureas. BBOCS symposium, The University of Queensland, Brisbane, Australia, 3 December, 2007.
Rands-Trevor, K., Blanchfield, J. T. and Garson, M. J. (2007). Towards the synthesis of [14C]-labelled axisonitrile-3 and its biosynthetic transformations in the marine sponge A. cavernosa. The 22nd Royal Australian Chemical Institute Inc. Organic Conference (22RACIOC), Adelaide, South Australia, 28 January - 2 February 2007.
Caccetta, Rima, Blanchfield, Joanne T., Harrison, Jessica, Toth, Istvan and Benson, Heather A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide. doi: 10.1007/s10989-006-9024-5
Wessling, S., Ross, B P, Blanchfield, J T and Toth, I (2006). Caco-2 cell permeability and stability assays of two d-glycopyranuronanamide conjugates of thyrotropic releasing hormone. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.
Drug development of endomorphin-1
Del Borgo, M, Koda, Y., Blanchfield, J T, Toth, I and Okada, Y. (2006). Drug development of endomorphin-1. 29th European Peptide Symposium, Gdansk, 3-8 Sept, 2006. CHICHESTER: JOHN WILEY & SONS LTD.
New sesquiterpenes from the sponge Acanthella cavernosa
Jumaryatno, P., Blanchfield, J. T. and Garson, M. J. (2006). New sesquiterpenes from the sponge Acanthella cavernosa. 12th Asian Symposium on Medicinal Plants, Spices and Other Nas, Padang, 13 - 18 November 2006.
Novel imidazole alkaloids from Leucetta-like Indonesian sponges
Swasono, R., Blanchfield, J T and Garson, M J (2006). Novel imidazole alkaloids from Leucetta-like Indonesian sponges. 12th Asian Symp on Medicinal Plants, Spices etc, Padang, November, 2006.
Synthesis and characterisation of Trp modified Leu-Enkephalin analogues
Del Borgo, M, Wang, R., Toth, I and Blanchfield, J T (2006). Synthesis and characterisation of Trp modified Leu-Enkephalin analogues. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.
The chemo-enzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery
Johnstone, Ken D., Dieckelmann, Manuela, Jennings, Michael P., Blanchfield, Joanne T. and Toth, Istvan (2006). The chemo-enzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, NY, United States: Springer. doi: 10.1007/978-0-387-26575-9_221
The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery
Johnstone, K.D., Dieckelmann, M., Jennings, M.P., Blanchfield, J.T. and Toth, I. (2005). The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. Hoboken, NJ, United States: John Wiley & Sons .
A novel liposaccharide system for the delivery of Endormorphin 1
Koda, Y., Blanchfield, J. T., Okada, Y. and Toth, I. (2004). A novel liposaccharide system for the delivery of Endormorphin 1. PSWC 2004, Kyoto, 29 May- 3 June, 2004.
Lipid and carbohydrate based macromolecules in drug and vaccine delivery
Toth, I., Horvath, A., Blanchfield, J. T., Olive, C., Good, M. F., Wimmer, N. and Rakoczy, E.P. (2004). Lipid and carbohydrate based macromolecules in drug and vaccine delivery. 18th American Peptide Symposium, Boston, 19-23 July, 2004.
Lipids and sugars in drug and gene delivery
Blanchfield, J. T. (2004). Lipids and sugars in drug and gene delivery. GPEN 2004, Kyoto, 26-28 May, 2004.
Liposaccharide delivery system: Application to Conotoxin MII and Endomorphin 1
Blanchfield, J. T., Koda, Y., Gallagher, O. P. and Toth, I. (2004). Liposaccharide delivery system: Application to Conotoxin MII and Endomorphin 1. 20th RACI Organic Chemistry Conference, Cairns, 4-8 July, 2004.
Liposaccharide delivery system: application to conotoxin MII and endomorphin I
Blanchfield, J. T., Koda, Y., Gallagher, O. P. and Toth, I. (2004). Liposaccharide delivery system: application to conotoxin MII and endomorphin I. PSWC 2004, Kyoto, 29 May - 3 June, 2004.
Liposaccharides in peptide drug delivery
Blanchfield, J. T., Gallagher, O. P., Koda, Y., Alewood, P.F., Lewis, R. J. and Toth, I. (2004). Liposaccharides in peptide drug delivery. 18th American Peptide Symposium, Boston, 19-23 July, 2003. WASHINGTON: AMER CHEMICAL SOC.
Lipid and carbohydrate based macromolecules in drug and vaccine delivery
Toth, I., Horvath, A., Blanchfield, J. T., Olive, C., Good, M. F., Wimmer, N. and Rakoczy, E. P. (2003). Lipid and carbohydrate based macromolecules in drug and vaccine delivery. Brisbane Biological and Organic Chemistry Symposium, Gold Coast, 28 November, 2003.
Liposaccharide delivery system: Application for peptide IT-100, LHRH and conotoxin MII
Blanchfield, J. T., Chan, Y., Rhee, H., Alewood, P.F., Adams, D. J. and Toth, I. (2003). Liposaccharide delivery system: Application for peptide IT-100, LHRH and conotoxin MII. 18th American Peptide Symposium, Boston, USA, 19-23 July, 2003. HOBOKEN: JOHN WILEY & SONS INC.
Liposacchride delivery system: Application to peptides conotoxin MII and endomorphin I
Blanchfield, J. T., Gallagher, O. P., Koda, Y. and Toth, I. (2003). Liposacchride delivery system: Application to peptides conotoxin MII and endomorphin I. Brisbane Biological and Organic Chemistry Symposium, Gold Coast, 28 Nov, 2003.
Study on polyisoprenylated benzophenones from fruit of Garcinia pichrorhiza
Swasono, R., Utami, S., Kosela, S., Blanchfield, J. T. and Garson, M. J. (2003). Study on polyisoprenylated benzophenones from fruit of Garcinia pichrorhiza. Brisbane Biological and Organic Chemistry Symposium, Gold Coast, 28 Sept - 3 Oct, 2003.
Liposaccharides in drug delivery
Toth, I., Blanchfield, J. T., McGeary, R. P., Ross, B. P. and Chan, Y. (2002). Liposaccharides in drug delivery. XX1st International Carbohydrate Symposium, Cairns, 7-12 July 2002.
Blanchfield, J. T. and Toth, I. (2002). Modify the bioactive to increase the availability and potency of a drug: Lipids and sugars in drug delivery and vaccine development. 8th International Pacific Rim Biotechnology Conference, Auckland, NZ, 17-20 Nov. 2002.
Toth, I., Mcgeary, R. P. and Blanchfield, J. T. (2001). Applications of lipoamino acids and liposaccharides for peptide delivery and enhancing immunogenicity. 2nd International Peptide Symposium, 17th American Peptide Symposium, San Diego, USA, 9-15 June 2001. San Diego, USA: American Peptide Society.
Enhancing peptide delivery using lipoamino acids and liposaccharides.
Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Toth, I. (2001). Enhancing peptide delivery using lipoamino acids and liposaccharides.. 7th International Symposium on Solid Phase Synthesis & Combinatorial Chemical Libraries, Southampton, UK, 18-22 Sept 2001. UK: European Peptide Society & BS/RSC Protein & Peptide Group, UK.
Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Good, M. F. (2001). Lipids and sugars: Application for peptide delivery and for enhancing synthetic peptide immunogenicity. 4th Australian Peptide Conference, Lindeman Is., Queensland, 7-12 Oct 2001.
Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P. F., Adams, D. J. and Good, M. F. (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity.. 2nd International & 17th American Peptide Symposium, San Diego, California, US, 9-14 June, 2001. San Diego, CA: American Peptide Society.
Novel liposaccharide based system for delivering LHRH orally.
Rhee, H., Blanchfield, J. T. and Toth, I. (2001). Novel liposaccharide based system for delivering LHRH orally.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.
Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.
Blanchfield, J. T., Dutton, J. L., Craik, D. J., Alewood, P.F., Lewis, R. J., Adams, D. J. and Toth, I. (2001). Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.. APSA Annual Conference 2001, Melbourne, Australia, 9-12 December, 2001. Melbourne, Australia: Australasian Pharmaceutical Science Association.
Synthesis of lipo- and liposacchride a-conotoxin MII conjugates
Blanchfield, J. T., Alewood, P.F., Lewis, R. J., Dutton, J. L., Craik, D. J. and Toth, I. (2001). Synthesis of lipo- and liposacchride a-conotoxin MII conjugates. World Chemistry Congress, Brisbane, Australia, 1-6 July, 2001. Royal Australian Chemical Institute.
The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.
Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.
The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.
Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. Brisbane Biological & Organic Chemistry Symposium 2001, University of Queensland, Brisbane, 30 Nov 2001. Brisbane:
A novel liposaccharide based system for peptide drug delivery
Blanchfield, J. T., Adams, D. J., Alewood, P. F., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The APSA 2000 Annual Conference, Newcastle, 6th - 8th December, 2000. Australia: APSA.
A novel liposaccharide based system for peptide drug delivery
Adams, D. J., Alewood, P. F., Blanchfield, J. T., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November. 2000.
The development of methodologies for C11 hydroxylation of all of the major classes of gibberellins
Blanchfield, J. T., Liu, J. and Mander, L. N. (2000). The development of methodologies for C11 hydroxylation of all of the major classes of gibberellins. The 11th Royal Australian Chemical Institute Convention, Canberra, ACT, Australia, 6-11 February 2000. Canberra, A.C.T., Australia: ANU.
Isolation, characterisation and synthesis of terrestrial and marine natural products
Blanchfield, Joanne Therese (1995). Isolation, characterisation and synthesis of terrestrial and marine natural products. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland.
(2020–2022) Commonwealth Defence Science and Technology Group
(2015–2016) Technology-Enhanced Learning Grants
Bioproduction and bioavailability of steroidal saponins, bioactives in herbal medicines
(2014–2017) ARC Linkage Projects
(2014–2015) UniQuest Pty Ltd
Assessing the oral bioavailability of components of herbal extracts using Caco-2 cell monolayers
(2010–2011) UQ FirstLink Scheme
(2009–2013) University of Vienna
(2008–2010) NHMRC Development Grant
Analytical and preparative enantioselective chromatography
(2008–2009) ARC Linkage Infrastructure, Equipment and Facilities
Next Generation Polymer Nanostructures
(2006–2008) ARC Discovery Projects
(2006) ARC Linkage Infrastructure, Equipment and Facilities
Synthesis Of Glycopeptide CNS Drug Candidates Applying Chemical And Chemo-Enzymatic Methods
(2004–2006) University of Queensland Research Development Grants Scheme
(2004–2005) NHMRC Development Grant
A combinatorial approach to creation of new epitopes with biological activity
(2003–2006) ARC Linkage Projects
A novel liposaccharide system for the delivery of opioid peptides across the blood brain barrier
(2003–2004) UQ New Staff Research Start-Up Fund
The construction of synthetic mimics of complex conformational epitopes of HIV
Doctor Philosophy — Principal Advisor
Other advisors:
Investigating natural products from herbal extracts
Doctor Philosophy — Principal Advisor
Other advisors:
Conotoxins - advanced probes for studying pain pathways
Doctor Philosophy — Associate Advisor
Other advisors:
Synthesis of peptide building blocks for production of glycopeptide antibiotics.
Doctor Philosophy — Associate Advisor
Other advisors:
Bioactive Phytochemicals from Australian Native Plants used as Ingienous medicines
Doctor Philosophy — Associate Advisor
Other advisors:
Decontamination of fentanyl and fentanyl analogues
(2023) Doctor Philosophy — Principal Advisor
Other advisors:
Phytochemical characterisation of Australian medicinal plants: Doctrina veteris et novi
(2021) Doctor Philosophy — Principal Advisor
Other advisors:
Physical and chemical interactions between bile pigments and polyaromatic mutagens
(2016) Doctor Philosophy — Principal Advisor
Other advisors:
(2013) Doctor Philosophy — Principal Advisor
Other advisors:
Targeting central nervous system active peptides to the brain via nasal delivery
(2009) Doctor Philosophy — Principal Advisor
Other advisors:
A NOVEL LIPOSACCHARIDE SYSTEM FOR THE DELIVERY OF ENDOMORPHIN1 ACROSS THE BLOOD-BRAIN BARRIER
(2007) Doctor Philosophy — Principal Advisor
Other advisors:
Cage Hydrocarbon Scaffolds for Viral Inhibition and Microlithography
(2022) Doctor Philosophy — Associate Advisor
Other advisors:
Biosynthesis of Steroidal Saponins
(2021) Doctor Philosophy — Associate Advisor
Other advisors:
(2021) Doctor Philosophy — Associate Advisor
Other advisors:
Synthesis of Mechanistic Probes for Cytochrome P450 Catalysed Desaturation
(2020) Doctor Philosophy — Associate Advisor
Other advisors:
Tagged Antibiotics for Examination of Bacterial Resistance and Infection
(2020) Doctor Philosophy — Associate Advisor
Other advisors:
Discovery of novel natural products from the Australian arid and semi-arid zones
(2019) Doctor Philosophy — Associate Advisor
Other advisors:
Phytochemistry of Gynostemma pentaphyllum (Thunb.) Makino
(2019) Doctor Philosophy — Associate Advisor
Other advisors:
SYNTHESIS OF STEROID CONJUGATES FOR TARGETED LIPOSOMAL DELIVERY OF RNA-BASED THERAPIES
(2019) Master Philosophy — Associate Advisor
Other advisors:
When East Meets West: The Chemistry of Indonesian Sponges and Australian Nudibranchs
(2017) Doctor Philosophy — Associate Advisor
Unusual cytochrome P450-catalysed reactions: synthesis of small molecule probes
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
CYP710C1: Mechanism and Design of Inhibitors
(2014) Doctor Philosophy — Associate Advisor
Other advisors:
Isolation and structure elucidation of bioactive secondary metabolites from Balinese marine sponges
(2014) Doctor Philosophy — Associate Advisor
Steroidal Saponins from Medicinal Herbs
(2013) Doctor Philosophy — Associate Advisor
Other advisors:
Chemical Studies of Marine Sponges from South-East Queensland
(2012) Doctor Philosophy — Associate Advisor
Cytochrome P450-catalysed oxidations: Biosynthetic and mechanistic studies
(2012) Doctor Philosophy — Associate Advisor
Other advisors:
Evidence of Enantiomeric Turnover in the Marine Sponge Acanthella cavernosa
(2012) Doctor Philosophy — Associate Advisor
Synthesis and Pharmacological Characterization of Endomorphin-1 Analogues
(2012) Doctor Philosophy — Associate Advisor
Other advisors:
Marine Natural Products from South-East Queensland: Secondary Metabolites from Sponges and Nudibranchs
(2011) Doctor Philosophy — Associate Advisor
Synthesis of Complex Polymer Topologies and Their Self-Assembly in Water
(2011) Doctor Philosophy — Associate Advisor
Other advisors:
(2008) Doctor Philosophy — Associate Advisor
Other advisors:
The efficacy of bile pigment supplementation: In vitro and in vivo considerations
(2008) Doctor Philosophy — Associate Advisor
Other advisors:
TOTAL SYNTHESIS OF PROPOSED ACTIVE CONSTITUENTS IN ECHINACEA. SP. AND CHAMALERIUM LEUTEUM
(2007) Doctor Philosophy — Associate Advisor
Other advisors:
BIOACTIVE SECONDARY METABOLITES FROM AUSTRALIAN INVERTEBRATES, INDONESIA MARINE SPONGES, AND AN INDONESIAN TERRESTRIAL PLANT
(2006) Master Philosophy — Associate Advisor
VACCINE-ADJUVANT-CARRIER DESIGN AGAINST GROUP A STREPTOCOCCUSI AND HUMAN PAPILLOMAVIRUS TYPE-16 INFECTION
(2006) Doctor Philosophy — Associate Advisor
Other advisors:
LIPOAMINO ACID- AND CARBOHYDRATE-BASED PENETRATION ENHANCERS FOR USE IN ORAL DRUG DELIVERY
(2004) Doctor Philosophy — Associate Advisor
Other advisors: